4.7 Article

Nebulosa recovers single-cell gene expression signals by kernel density estimation

期刊

BIOINFORMATICS
卷 37, 期 16, 页码 2485-2487

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OXFORD UNIV PRESS
DOI: 10.1093/bioinformatics/btab003

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资金

  1. University of Queensland
  2. National Health and Medical Research Council [1175781, APP1143163]
  3. Australian Research Council [DP180101405]
  4. National Health and Medical Research Council of Australia [1175781] Funding Source: NHMRC

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Nebulosa is an R package that utilizes weighted kernel density estimation to recover lost signals caused by data sparsity in single-cell experiments, improving the accurate assessment of gene expression.
Data sparsity in single-cell experiments prevents an accurate assessment of gene expression when visualized in a low-dimensional space. Here, we introduce Nebulosa, an R package that uses weighted kernel density estimation to recover signals lost through drop-out or low expression.

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