The C. elegans PAQR-2 and IGLR-2 membrane homeostasis proteins are uniquely essential for tolerating dietary saturated fats

Extensive transcription mis-regulation and membrane defects in AdipoR2-deficient cells challenged with saturated fatty acids

(2021) Mario Ruiz et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Regulation of lipid saturation without sensing membrane fluidity

(2020) Stephanie Ballweg et al.   Nature Communications

Genetic Screen for Cell Fitness in High or Low Oxygen Highlights Mitochondrial and Lipid Metabolism

(2020) Isha H. Jain et al.   CELL

Lipidomic and biophysical homeostasis of mammalian membranes counteracts dietary lipid perturbations to maintain cellular fitness

(2020) Kandice R. Levental et al.   Nature Communications

Leveraging a gain-of-function allele of Caenorhabditis elegans paqr-1 to elucidate membrane homeostasis by PAQR proteins

(2020) Kiran Busayavalasa et al.   PLoS Genetics

CHP1 Regulates Compartmentalized Glycerolipid Synthesis by Activating GPAT4

(2019) Xiphias Ge Zhu et al.   MOLECULAR CELL

Probing the Global Cellular Responses to Lipotoxicity Caused by Saturated Fatty Acids

(2019) Manuele Piccolis et al.   MOLECULAR CELL

AdipoR1 and AdipoR2 Maintain Membrane Fluidity in Most Human Cell Types and Independently of Adiponectin

(2019) Mario Ruiz et al.   JOURNAL OF LIPID RESEARCH

Dietary fats and cardiometabolic disease: mechanisms and effects on risk factors and outcomes

(2019) Jason H. Y. Wu et al.   Nature Reviews Cardiology

Control of membrane lipid homeostasis by lipid-bilayer associated sensors: A mechanism conserved from bacteria to humans

(2019) Diego de Mendoza et al.   PROGRESS IN LIPID RESEARCH

Evolutionarily conserved long-chain Acyl-CoA synthetases regulate membrane composition and fluidity

(2019) Mario Ruiz et al.   eLife

Membrane Fluidity Is Regulated Cell Non-autonomously byCaenorhabditiselegansPAQR-2 and Its Mammalian Homolog AdipoR2

(2018) Rakesh Bodhicharla et al.   GENETICS

Membrane Fluidity Is Regulated Cell Non-autonomously byCaenorhabditiselegansPAQR-2 and Its Mammalian Homolog AdipoR2

(2018) Rakesh Bodhicharla et al.   GENETICS

Membrane fluidity is regulated by the C. elegans transmembrane protein FLD-1 and its human homologs TLCD1/2

(2018) Mario Ruiz et al.   eLife

Structural insights into adiponectin receptors suggest ceramidase activity

(2017) Ieva Vasiliauskaité-Brooks et al.   NATURE

SREBP-regulated lipid metabolism: convergent physiology — divergent pathophysiology

(2017) Hitoshi Shimano et al.   Nature Reviews Endocrinology

Sphingolipids and their metabolism in physiology and disease

(2017) Yusuf A. Hannun et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The adiponectin receptor AdipoR2 and its Caenorhabditis elegans homolog PAQR-2 prevent membrane rigidification by exogenous saturated fatty acids

(2017) Ranjan Devkota et al.   PLoS Genetics

Palmitic Acid: Physiological Role, Metabolism and Nutritional Implications

(2017) Gianfranca Carta et al.   Frontiers in Physiology

The BUME method: a new rapid and simple chloroform-free method for total lipid extraction of animal tissue

(2016) Lars Löfgren et al.   Scientific Reports

Activation of the bacterial thermosensor DesK involves a serine zipper dimerization motif that is modulated by bilayer thickness

(2015) Larisa Estefanía Cybulski et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

From zero to six double bonds: phospholipid unsaturation and organelle function

(2015) Bruno Antonny et al.   TRENDS IN CELL BIOLOGY

13C- and 15N-Labeling Strategies Combined with Mass Spectrometry Comprehensively Quantify Phospholipid Dynamics in C. elegans

(2015) Blair C. R. Dancy et al.   PLoS One

Regulation of lipid droplet size and phospholipid composition by stearoyl-CoA desaturase

(2013) Xun Shi et al.   JOURNAL OF LIPID RESEARCH

PAQR-2 Regulates Fatty Acid Desaturation during Cold Adaptation in C. elegans

(2013) Emma Svensk et al.   PLoS Genetics

Fatty acid composition of membrane bilayers: Importance of diet polyunsaturated fat balance

(2012) Sarah K. Abbott et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

NIH Image to ImageJ: 25 years of image analysis

(2012) Caroline A Schneider et al.   NATURE METHODS

High throughput quantitative molecular lipidomics

(2011) Hye R. Jung et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

CREST - a large and diverse superfamily of putative transmembrane hydrolases

(2011) Jimin Pei et al.   Biology Direct

The Adiponectin Receptor Homologs in C. elegans Promote Energy Utilization and Homeostasis

(2011) Emma Svensson et al.   PLoS One

Receptor-mediated activation of ceramidase activity initiates the pleiotropic actions of adiponectin

(2010) William L Holland et al.   NATURE MEDICINE

Antagonism of Human Adiponectin Receptors and Their Membrane Progesterone Receptor Paralogs by TNFα and a Ceramidase Inhibitor

(2009) Brian R. Kupchak et al.   BIOCHEMISTRY

The Influence of Bacterial Diet on Fat Storage in C. elegans

(2009) Kyleann K. Brooks et al.   PLoS One

Global analysis of the yeast lipidome by quantitative shotgun mass spectrometry

(2009) C. S. Ejsing et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A 13C Isotope Labeling Strategy Reveals the Influence of Insulin Signaling on Lipogenesis in C. elegans

(2008) Carissa L. Perez et al.   Cell Metabolism