MiRNAs directly targeting the key intermediates of biological pathways in pancreatic cancer
出版年份 2020 全文链接
标题
MiRNAs directly targeting the key intermediates of biological pathways in pancreatic cancer
作者
关键词
MicroRNAs, Onco-targets, Clinical applications, Natural compounds
出版物
BIOCHEMICAL PHARMACOLOGY
Volume -, Issue -, Pages 114357
出版商
Elsevier BV
发表日期
2020-12-04
DOI
10.1016/j.bcp.2020.114357
参考文献
相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。- Cancer statistics, 2020
- (2020) Rebecca L. Siegel et al. CA-A CANCER JOURNAL FOR CLINICIANS
- Long non-coding RNA OIP5-AS1 promotes pancreatic cancer cell growth through sponging miR-342-3p via AKT/ERK signaling pathway
- (2020) Xiangpeng Meng et al. JOURNAL OF PHYSIOLOGY AND BIOCHEMISTRY
- Blocking Parkin/PINK1-mediated mitophagy sensitizes hepatocellular carcinoma cells to sanguinarine-induced mitochondrial apoptosis
- (2020) Qi Su et al. TOXICOLOGY IN VITRO
- Small Molecule KRAS Agonist for Mutant KRAS Cancer Therapy
- (2019) Ke Xu et al. Molecular Cancer
- Long noncoding RNA LINC00473 drives the progression of pancreatic cancer via upregulating programmed death-ligand 1 by sponging microRNA-195-5p
- (2019) Wen-Yang Zhou et al. JOURNAL OF CELLULAR PHYSIOLOGY
- WNT Signaling in Disease
- (2019) Ng et al. Cells
- MicroRNAs in Pancreatic Cancer: biomarkers, prognostic, and therapeutic modulators
- (2019) Afra Z. Daoud et al. BMC CANCER
- Homoharringtonine suppresses LoVo cell growth by inhibiting EphB4 and the PI3K/AKT and MAPK/EKR1/2 signaling pathways
- (2019) Xianpeng Shi et al. FOOD AND CHEMICAL TOXICOLOGY
- Insulin-like growth factor 2 mRNA-binding protein 1 promotes cell proliferation via activation of AKT and is directly targeted by microRNA-494 in pancreatic cancer
- (2019) Bai-Shun Wan et al. WORLD JOURNAL OF GASTROENTEROLOGY
- New avenues in pancreatic cancer: exploiting microRNAs as predictive biomarkers and new approaches to target aberrant metabolism
- (2019) Mjriam Capula et al. Expert Review of Clinical Pharmacology
- Autophagy in cancer: moving from understanding mechanism to improving therapy responses in patients
- (2019) Jean M. Mulcahy Levy et al. CELL DEATH AND DIFFERENTIATION
- Glycogen synthase kinases: Moonlighting proteins with theranostic potential in cancer
- (2018) Siddavaram Nagini et al. SEMINARS IN CANCER BIOLOGY
- LncRNA SNHG7 sponges miR-216b to promote proliferation and liver metastasis of colorectal cancer through upregulating GALNT1
- (2018) Yujia Shan et al. Cell Death & Disease
- Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries
- (2018) Freddie Bray et al. CA-A CANCER JOURNAL FOR CLINICIANS
- Regulation of MicroRNAs by Natural Products and Bioactive Compounds Obtained From Common Medicinal Plants: Novel Strategy in Cancer Therapy
- (2017) Sevgi Gezici et al. Indian Journal of Pharmaceutical Education and Research
- miR-92b-3p acts as a tumor suppressor by targeting Gabra3 in pancreatic cancer
- (2017) Manmei Long et al. Molecular Cancer
- MicroRNA-296 targets AKT2 in pancreatic cancer and functions as a potential tumor suppressor
- (2017) Hailing Li et al. Molecular Medicine Reports
- MicroRNA-448 suppresses metastasis of pancreatic ductal adenocarcinoma through targeting JAK1/STAT3 pathway
- (2017) Dan-Li Yu et al. ONCOLOGY REPORTS
- MicroRNA regulation of K-Ras in pancreatic cancer and opportunities for therapeutic intervention
- (2017) Saswati Karmakar et al. SEMINARS IN CANCER BIOLOGY
- Targeting miRNAs by polyphenols: Novel therapeutic strategy for cancer
- (2017) Kasi Pandima Devi et al. SEMINARS IN CANCER BIOLOGY
- Curcumin induces apoptotic cell death in human pancreatic cancer cells via the miR-340/XIAP signaling pathway
- (2017) Deying Yang et al. Oncology Letters
- KRAS: The Critical Driver and Therapeutic Target for Pancreatic Cancer
- (2017) Andrew M. Waters et al. Cold Spring Harbor Perspectives in Medicine
- The TGF-β/Smad4 Signaling Pathway in Pancreatic Carcinogenesis and Its Clinical Significance
- (2017) Sunjida Ahmed et al. Journal of Clinical Medicine
- Over-expression of microRNA-940 promotes cell proliferation by targeting GSK3β and sFRP1 in human pancreatic carcinoma
- (2016) Hong-wei Yang et al. BIOMEDICINE & PHARMACOTHERAPY
- Transcriptional Regulation of miR-31 by Oncogenic KRAS Mediates Metastatic Phenotypes by Repressing RASA1
- (2016) O. A. Kent et al. MOLECULAR CANCER RESEARCH
- Prognostic Value of SMAD4 in Pancreatic Cancer: A Meta-Analysis
- (2016) Xing Shugang et al. Translational Oncology
- Hypoxia-induced lncRNA-NUTF2P3-001 contributes to tumorigenesis of pancreatic cancer by derepressing the miR-3923/KRAS pathway
- (2016) Xiang Li et al. Oncotarget
- Targeting microRNAs: a new action mechanism of natural compounds
- (2016) Qian Lin et al. Oncotarget
- Emerging Role and Therapeutic Implication of Wnt Signaling Pathways in Autoimmune Diseases
- (2016) Juan Shi et al. Journal of Immunology Research
- Aryl amide small-molecule inhibitors of microRNA miR-21 function
- (2015) Yuta Naro et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Akt inhibitors in cancer treatment: The long journey from drug discovery to clinical use (Review)
- (2015) GEORGE MIHAI NITULESCU et al. INTERNATIONAL JOURNAL OF ONCOLOGY
- MiR-744 increases tumorigenicity of pancreatic cancer by activating Wnt/β-catenin pathway
- (2015) Wei Zhou et al. Oncotarget
- MicroRNA-301a-3p promotes pancreatic cancer progression via negative regulation of SMAD4
- (2015) Xiang Xia et al. Oncotarget
- Micro-RNA-155 is induced by K-Ras oncogenic signal and promotes ROS stress in pancreatic cancer
- (2015) Peng Wang et al. Oncotarget
- Redox regulation of FoxO transcription factors
- (2015) Lars-Oliver Klotz et al. Redox Biology
- MiRNA-615-5p Functions as a Tumor Suppressor in Pancreatic Ductal Adenocarcinoma by Targeting AKT2
- (2015) Yang Sun et al. PLoS One
- Oncogenic KRAS signalling in pancreatic cancer
- (2014) S Eser et al. BRITISH JOURNAL OF CANCER
- Projecting Cancer Incidence and Deaths to 2030: The Unexpected Burden of Thyroid, Liver, and Pancreas Cancers in the United States
- (2014) L. Rahib et al. CANCER RESEARCH
- MicroRNA-375 targets PDK1 in pancreatic carcinoma and suppresses cell growth through the Akt signaling pathway
- (2014) JIAN ZHOU et al. INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE
- miRNAs for the Detection of MultiDrug Resistance: Overview and Perspectives
- (2014) Andreas Gisel et al. MOLECULES
- MicroRNA-206 functions as a pleiotropic modulator of cell proliferation, invasion and lymphangiogenesis in pancreatic adenocarcinoma by targeting ANXA2 and KRAS genes
- (2014) I Keklikoglou et al. ONCOGENE
- MicroRNA-216a inhibits pancreatic cancer by directly targeting Janus kinase 2
- (2014) SILIANG WANG et al. ONCOLOGY REPORTS
- Curcumin inhibits cell growth and invasion through up-regulation of miR-7 in pancreatic cancer cells
- (2014) Jia Ma et al. TOXICOLOGY LETTERS
- MicroRNA expression profiling of diagnostic needle aspirates from surgical pancreatic cancer specimens
- (2014) Tae Ho Hong et al. Annals of Surgical Treatment and Research
- Peroxisome Proliferator-Activated Receptor γ Coactivator 1α and FoxO3A Mediate Chondroprotection by AMP-Activated Protein Kinase
- (2014) Xianling Zhao et al. Arthritis & Rheumatology
- Chronic Inflammation and Cytokines in the Tumor Microenvironment
- (2014) Glauben Landskron et al. Journal of Immunology Research
- MicroRNA Array Analysis Finds Elevated Serum miR-1290 Accurately Distinguishes Patients with Low-Stage Pancreatic Cancer from Healthy and Disease Controls
- (2013) A. Li et al. CLINICAL CANCER RESEARCH
- Genistein Down-Regulates miR-223 Expression in Pancreatic Cancer Cells
- (2013) Jia Ma et al. CURRENT DRUG TARGETS
- Dynamic Methylation of Numb by Set8 Regulates Its Binding to p53 and Apoptosis
- (2013) Gurpreet Kaur Dhami et al. MOLECULAR CELL
- MiR-130b Is a Prognostic Marker and Inhibits Cell Proliferation and Invasion in Pancreatic Cancer through Targeting STAT3
- (2013) Gang Zhao et al. PLoS One
- Direct interaction between STAT3 and EIF2AK2 controls fatty acid-induced autophagy
- (2012) Mireia Niso-Santano et al. Autophagy
- Genistein Inhibits Cell Growth and Induces Apoptosis Through Up-regulation of miR-34a in Pancreatic Cancer Cells
- (2012) Jun Xia et al. CURRENT DRUG TARGETS
- Diagnostic, prognostic, and predictive biomarkers in pancreatic cancer
- (2012) Jordan M. Winter et al. JOURNAL OF SURGICAL ONCOLOGY
- Cytoplasmic STAT3 Represses Autophagy by Inhibiting PKR Activity
- (2012) Shensi Shen et al. MOLECULAR CELL
- JAK/STAT signaling in hematological malignancies
- (2012) W Vainchenker et al. ONCOGENE
- Wnt Signaling in Cancer
- (2012) P. Polakis Cold Spring Harbor Perspectives in Biology
- MicroRNA 421 suppresses DPC4/Smad4 in pancreatic cancer
- (2011) Jun Hao et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- miR-132 and miR-212 are increased in pancreatic cancer and target the retinoblastoma tumor suppressor
- (2011) Jong-Kook Park et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Stat3/Socs3 Activation by IL-6 Transsignaling Promotes Progression of Pancreatic Intraepithelial Neoplasia and Development of Pancreatic Cancer
- (2011) Marina Lesina et al. CANCER CELL
- Loss of Nuclear Localized and Tyrosine Phosphorylated Stat5 in Breast Cancer Predicts Poor Clinical Outcome and Increased Risk of Antiestrogen Therapy Failure
- (2011) Amy R. Peck et al. JOURNAL OF CLINICAL ONCOLOGY
- Curcumin: A review of anti-cancer properties and therapeutic activity in head and neck squamous cell carcinoma
- (2011) Reason Wilken et al. Molecular Cancer
- Regulation and function of miRNA-21 in health and disease
- (2011) Regalla Kumarswamy et al. RNA Biology
- miRNA-96 Suppresses KRAS and Functions as a Tumor Suppressor Gene in Pancreatic Cancer
- (2010) S. Yu et al. CANCER RESEARCH
- MicroRNA 483-3p suppresses the expression of DPC4/Smad4 in pancreatic cancer
- (2010) Jun Hao et al. FEBS LETTERS
- Death pathways triggered by activated Ras in cancer cells
- (2010) Jean et al. Frontiers in Bioscience-Landmark
- Repression of the miR-143/145 cluster by oncogenic Ras initiates a tumor-promoting feed-forward pathway
- (2010) O. A. Kent et al. GENES & DEVELOPMENT
- MicroRNA-20a Overexpression Inhibited Proliferation and Metastasis of Pancreatic Carcinoma Cells
- (2010) Haijiao Yan et al. HUMAN GENE THERAPY
- Up-regulation of miR-200 and let-7 by Natural Agents Leads to the Reversal of Epithelial-to-Mesenchymal Transition in Gemcitabine-Resistant Pancreatic Cancer Cells
- (2009) Y. Li et al. CANCER RESEARCH
- Retinoic Acid Receptor Antagonists Inhibit miR-10a Expression and Block Metastatic Behavior of Pancreatic Cancer
- (2009) Frank Ulrich Weiss et al. GASTROENTEROLOGY
- Role of miR-143 targeting KRAS in colorectal tumorigenesis
- (2009) X Chen et al. ONCOGENE
- Antisense Inhibition of microRNA-21 or -221 Arrests Cell Cycle, Induces Apoptosis, and Sensitizes the Effects of Gemcitabine in Pancreatic Adenocarcinoma
- (2009) Jong-Kook Park et al. PANCREAS
- p53 represses c-Myc through induction of the tumor suppressor miR-145
- (2009) M. Sachdeva et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Small-Molecule Inhibitors of MicroRNA miR-21 Function
- (2008) Kiranmai Gumireddy et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Pancreatic Cancer
- (2008) Anirban Maitra et al. Annual Review of Pathology-Mechanisms of Disease
- Multi-targeted therapy of cancer by genistein
- (2008) Sanjeev Banerjee et al. CANCER LETTERS
- The impact of microRNAs on protein output
- (2008) Daehyun Baek et al. NATURE
- Pancreatic Carcinogenesis
- (2008) Jan-Bart M. Koorstra et al. PANCREATOLOGY
- Profiling of 95 MicroRNAs in Pancreatic Cancer Cell Lines and Surgical Specimens by Real-Time PCR Analysis
- (2008) Yuqing Zhang et al. WORLD JOURNAL OF SURGERY
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started