Transglutaminase 2: a novel therapeutic target for idiopathic pulmonary fibrosis using selective small molecule inhibitors

Incidence, Prevalence, and Survival of Patients with Idiopathic Pulmonary Fibrosis in the UK

(2018) Helen Strongman et al.   ADVANCES IN THERAPY

Extracellular Matrix Cross-Linking Enhances Fibroblast Growth and Protects against Matrix Proteolysis in Lung Fibrosis

(2018) Christopher J. Philp et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Cardiac fibrosis can be attenuated by blocking the activity of transglutaminase 2 using a selective small-molecule inhibitor

(2018) Zhuo Wang et al.   Cell Death & Disease

Emerging therapies for idiopathic pulmonary fibrosis, a progressive age-related disease

(2017) Ana L. Mora et al.   NATURE REVIEWS DRUG DISCOVERY

The functional relationship between transglutaminase 2 and transforming growth factor β1 in the regulation of angiogenesis and endothelial–mesenchymal transition

(2017) Zhuo Wang et al.   Cell Death & Disease

Tissue transglutaminase induces Epithelial-Mesenchymal-Transition and the acquisition of stem cell like characteristics in colorectal cancer cells

(2017) Oluseyi Ayinde et al.   Oncotarget

A novel regulatory role for tissue transglutaminase in epithelial-mesenchymal transition in cystic fibrosis

(2016) Samuel Nyabam et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Development of Potent and Selective Tissue Transglutaminase Inhibitors: Their Effect on TG2 Function and Application in Pathological Conditions

(2015) Eduard Badarau et al.   CHEMISTRY & BIOLOGY

Matrix Metalloproteinase Mediated Type I Collagen Degradation — An Independent Risk Factor for Mortality in Women

(2015) K. Dragsbæk et al.   EBioMedicine

Diagnosis and classification of idiopathic pulmonary fibrosis

(2014) Alana Kekevian et al.   AUTOIMMUNITY REVIEWS

Inhibition of Transglutaminase 2, a Novel Target for Pulmonary Fibrosis, by Two Small Electrophilic Molecules

(2013) Keith C. Olsen et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Induction of chondrogenic differentiation in mesenchymal stem cells by TGF-beta cross-linked to collagen-PLLA [poly(l-lactic acid)] scaffold by transglutaminase 2

(2013) Corinne Niger et al.   BIOTECHNOLOGY LETTERS

Imidazolium-based warheads strongly influence activity of water-soluble peptidic transglutaminase inhibitors

(2013) Eduard Badarau et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

The Role of TG2 in Regulating S100A4-Mediated Mammary Tumour Cell Migration

(2013) Zhuo Wang et al.   PLoS One

Thioredoxin Is Involved in Endothelial Cell Extracellular Transglutaminase 2 Activation Mediated by Celiac Disease Patient IgA

(2013) Cristina Antonella Nadalutti et al.   PLoS One

A novel extracellular role for tissue transglutaminase in matrix-bound VEGF-mediated angiogenesis

(2013) Z Wang et al.   Cell Death & Disease

The role of TG2 in ECV304-related vasculogenic mimicry

(2012) Richard A. Jones et al.   AMINO ACIDS

Characterization of Heparin-binding Site of Tissue Transglutaminase

(2012) Zhuo Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Transglutaminase 2 and Its Role in Pulmonary Fibrosis

(2011) Keith C. Olsen et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

TG2, a novel extracellular protein with multiple functions

(2011) Zhuo Wang et al.   AMINO ACIDS

Epithelial transglutaminase 2 is needed for T cell interleukin-17 production and subsequent pulmonary inflammation and fibrosis in bleomycin-treated mice

(2011) Keunhee Oh et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The role of tissue transglutaminase (TG2) in regulating the tumour progression of the mouse colon carcinoma CT26

(2010) Panayiotis Kotsakis et al.   AMINO ACIDS

Importance of syndecan-4 and syndecan -2 in osteoblast cell adhesion and survival mediated by a tissue transglutaminase−fibronectin complex

(2010) Z. Wang et al.   EXPERIMENTAL CELL RESEARCH

RGD-independent Cell Adhesion via a Tissue Transglutaminase-Fibronectin Matrix Promotes Fibronectin Fibril Deposition and Requires Syndecan-4/2 and α5β1 Integrin Co-signaling

(2010) Zhuo Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Transglutaminase 2 cross-linking of matrix proteins: biological significance and medical applications

(2008) R. J. Collighan et al.   AMINO ACIDS