The genetic architecture of appendicular lean mass characterized by association analysis in the UK Biobank study

Genome-wide association analyses of chronotype in 697,828 individuals provides insights into circadian rhythms

(2019) Samuel E. Jones et al.   Nature Communications

Genome-wide Associations Reveal Human-Mouse Genetic Convergence and Modifiers of Myogenesis, CPNE1 and STC2

(2019) Ana I. Hernandez Cordero et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Heritability enrichment of specifically expressed genes identifies disease-relevant tissues and cell types

(2018) Hilary K. Finucane et al.   NATURE GENETICS

Causal associations between risk factors and common diseases inferred from GWAS summary data

(2018) Zhihong Zhu et al.   Nature Communications

OUP accepted manuscript

(2018)   AGE AND AGEING

Meta-analysis of genome-wide association studies for height and body mass index in ∼700000 individuals of European ancestry

(2018) Loic Yengo et al.   HUMAN MOLECULAR GENETICS

Genomic atlas of the human plasma proteome

(2018) Benjamin B. Sun et al.   NATURE

Rare and low-frequency coding variants alter human adult height

(2017) Eirini Marouli et al.   NATURE

Large meta-analysis of genome-wide association studies identifies five loci for lean body mass

(2017) M. Carola Zillikens et al.   Nature Communications

Bivariate genome-wide association meta-analysis of pediatric musculoskeletal traits reveals pleiotropic effects at the SREBF1/TOM1L2 locus

(2017) Carolina Medina-Gomez et al.   Nature Communications

Gene-based genome-wide association study identified 19p13.3 for lean body mass

(2017) Shu Ran et al.   Scientific Reports

Effects of Exercise and Aging on Skeletal Muscle

(2017) Giovanna Distefano et al.   Cold Spring Harbor Perspectives in Medicine

A simple yet accurate correction for winner's curse can predict signals discovered in much larger genome scans

(2016) T. Bernard Bigdeli et al.   BIOINFORMATICS

Contribution of Heritability and Epigenetic Factors to Skeletal Muscle Mass Variation in United Kingdom Twins

(2016) Gregory Livshits et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Genetic Variant in ACVR2B Is Associated with Lean Mass

(2016) YANN C. KLIMENTIDIS et al.   MEDICINE AND SCIENCE IN SPORTS AND EXERCISE

Integration of summary data from GWAS and eQTL studies predicts complex trait gene targets

(2016) Zhihong Zhu et al.   NATURE GENETICS

Modeling Linkage Disequilibrium Increases Accuracy of Polygenic Risk Scores

(2015) Bjarni J. Vilhjálmsson et al.   AMERICAN JOURNAL OF HUMAN GENETICS

New genetic loci link adipose and insulin biology to body fat distribution

(2015) Dmitry Shungin et al.   NATURE

Contrasting genetic architectures of schizophrenia and other complex diseases using fast variance-components analysis

(2015) Po-Ru Loh et al.   NATURE GENETICS

Partitioning heritability by functional annotation using genome-wide association summary statistics

(2015) Hilary K Finucane et al.   NATURE GENETICS

Gene expression analysis identifies global gene dosage sensitivity in cancer

(2015) Rudolf S N Fehrmann et al.   NATURE GENETICS

LD Score regression distinguishes confounding from polygenicity in genome-wide association studies

(2015) Brendan K Bulik-Sullivan et al.   NATURE GENETICS

Efficient Bayesian mixed-model analysis increases association power in large cohorts

(2015) Po-Ru Loh et al.   NATURE GENETICS

Muscle loss and obesity: the health implications of sarcopenia and sarcopenic obesity

(2015) S. Goya Wannamethee et al.   PROCEEDINGS OF THE NUTRITION SOCIETY

The Genotype-Tissue Expression (GTEx) pilot analysis: Multitissue gene regulation in humans

(2015) et al.   SCIENCE

Biological interpretation of genome-wide association studies using predicted gene functions

(2015) Tune H. Pers et al.   Nature Communications

MAGMA: Generalized Gene-Set Analysis of GWAS Data

(2015) Christiaan A. de Leeuw et al.   PLoS Computational Biology

Second-generation PLINK: rising to the challenge of larger and richer datasets

(2015) Christopher C Chang et al.   GigaScience

Large-scale analysis reveals a functional single-nucleotide polymorphism in the 5′-flanking region ofPRDM16gene associated with lean body mass

(2014) Tomohiko Urano et al.   AGING CELL

Defining the role of common variation in the genomic and biological architecture of adult human height

(2014) Andrew R Wood et al.   NATURE GENETICS

dbNSFP v2.0: A Database of Human Non-synonymous SNVs and Their Functional Predictions and Annotations

(2013) Xiaoming Liu et al.   HUMAN MUTATION

Prevalence of sarcopenia in Japanese women with osteopenia and osteoporosis

(2013) Naohisa Miyakoshi et al.   JOURNAL OF BONE AND MINERAL METABOLISM

Systematic identification of trans eQTLs as putative drivers of known disease associations

(2013) Harm-Jan Westra et al.   NATURE GENETICS

What’s in a name revisited: should osteoporosis and sarcopenia be considered components of “dysmobility syndrome?”

(2013) N. Binkley et al.   OSTEOPOROSIS INTERNATIONAL

Predicting the Functional, Molecular, and Phenotypic Consequences of Amino Acid Substitutions using Hidden Markov Models

(2012) Hashem A. Shihab et al.   HUMAN MUTATION

Predicting the Functional Effect of Amino Acid Substitutions and Indels

(2012) Yongwook Choi et al.   PLoS One

The mystery of missing heritability: Genetic interactions create phantom heritability

(2012) O. Zuk et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Bivariate genome-wide association study suggests that the DARC gene influences lean body mass and age at menarche

(2012) Rong Hai et al.   Science China-Life Sciences

GCTA: A Tool for Genome-wide Complex Trait Analysis

(2010) Jian Yang et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Robust relationship inference in genome-wide association studies

(2010) Ani Manichaikul et al.   BIOINFORMATICS

METAL: fast and efficient meta-analysis of genomewide association scans

(2010) C. J. Willer et al.   BIOINFORMATICS

A method and server for predicting damaging missense mutations

(2010) Ivan A Adzhubei et al.   NATURE METHODS

Genome-wide Association and Replication Studies Identified TRHR as an Important Gene for Lean Body Mass

(2009) Xiao-Gang Liu et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Finding the missing heritability of complex diseases

(2009) Teri A. Manolio et al.   NATURE

Predicting the effects of coding non-synonymous variants on protein function using the SIFT algorithm

(2009) Prateek Kumar et al.   Nature Protocols

Association of body composition with disability in rheumatoid arthritis: Impact of appendicular fat and lean tissue mass

(2008) Jon T. Giles et al.   ARTHRITIS AND RHEUMATISM

Cachexia: A new definition

(2008) William J. Evans et al.   CLINICAL NUTRITION

Genetics of the Musculoskeletal System: A Pleiotropic Approach

(2008) David Karasik et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Genome-wide association analysis of metabolic traits in a birth cohort from a founder population

(2008) Chiara Sabatti et al.   NATURE GENETICS