Next-Generation Pertussis Vaccines Based on the Induction of Protective T Cells in the Respiratory Tract

Live attenuated pertussis vaccine BPZE1 induces a broad antibody response in humans

(2020) Ang Lin et al.   JOURNAL OF CLINICAL INVESTIGATION

Intranasal immunization with outer membrane vesicle pertussis vaccine confers broad protection through mucosal IgA and Th17 responses

(2020) René H. M. Raeven et al.   Scientific Reports

Influenza infection fortifies local lymph nodes to promote lung-resident heterosubtypic immunity

(2020) Daniel H. Paik et al.   JOURNAL OF EXPERIMENTAL MEDICINE

SARS-CoV-2 vaccines in development

(2020) Florian Krammer   NATURE

Immunization with whole cell but not acellular pertussis vaccines primes CD4 TRM cells that sustain protective immunity against nasal colonization with Bordetella pertussis

(2019) Mieszko M. Wilk et al.   Emerging Microbes & Infections

The Role of Mucosal Immunity in Pertussis

(2019) Luis Solans et al.   Frontiers in Immunology

Neonatal Immunity to Bordetella pertussis Infection and Current Prevention Strategies

(2019) Carolina Argondizo-Correia et al.   Journal of Immunology Research

Pertactin-deficient Bordetella pertussis isolates: evidence of increased circulation in Europe, 1998 to 2015

(2019) Alex-Mikael Barkoff et al.   Eurosurveillance

A Pertussis Outer Membrane Vesicle-Based Vaccine Induces Lung-Resident Memory CD4 T Cells and Protection Against Bordetella pertussis, Including Pertactin Deficient Strains

(2019) María Eugenia Zurita et al.   Frontiers in Cellular and Infection Microbiology

Mucosal vaccines and technology

(2019) A. Miquel‐Clopés et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Novel approaches for the design, delivery and administration of vaccine technologies

(2019) J. Wallis et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Pertussis vaccines and protective immunity

(2019) Parul Kapil et al.   CURRENT OPINION IN IMMUNOLOGY

Early Protection against Pertussis Induced by Live Attenuated Bordetella pertussis BPZE1 Depends on TLR4

(2019) Anne-Sophie Debrie et al.   JOURNAL OF IMMUNOLOGY

Bystander Activation of Pulmonary Trm Cells Attenuates the Severity of Bacterial Pneumonia by Enhancing Neutrophil Recruitment

(2019) Chenghao Ge et al.   Cell Reports

More Than Just Attractive: How CCL2 Influences Myeloid Cell Behavior Beyond Chemotaxis

(2019) Martha Gschwandtner et al.   Frontiers in Immunology

The vaccine adjuvant alum promotes IL-10 production that suppresses Th1 responses

(2018) Ewa Oleszycka et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Evaluation of adenylate cyclase toxoid antigen in acellular pertussis vaccines using a Bordetella pertussis challenge model in mice.

(2018) Dylan T. Boehm et al.   INFECTION AND IMMUNITY

Investigation of the Cellular Immune Response to Recombinant Fragments of Filamentous Hemagglutinin and Pertactin of Bordetella pertussis in BALB/c Mice

(2018) Peyman Bakhshaei et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

Prevention of tuberculosis in rhesus macaques by a cytomegalovirus-based vaccine

(2018) Scott G Hansen et al.   NATURE MEDICINE

STING-Activating Adjuvants Elicit a Th17 Immune Response and Protect against Mycobacterium tuberculosis Infection

(2018) Erik Van Dis et al.   Cell Reports

Whole-Cell or Acellular Pertussis Primary Immunizations in Infancy Determines Adolescent Cellular Immune Profiles

(2018) Saskia van der Lee et al.   Frontiers in Immunology

T Cells Primed by Live Mycobacteria Versus a Tuberculosis Subunit Vaccine Exhibit Distinct Functional Properties

(2018) Thomas Lindenstrøm et al.   EBioMedicine

Th1/Th17 polarization persists following whole-cell pertussis vaccination despite repeated acellular boosters

(2018) Ricardo da Silva Antunes et al.   JOURNAL OF CLINICAL INVESTIGATION

IL-17-dependent SIgA-mediated protection against nasal Bordetella pertussis infection by live attenuated BPZE1 vaccine

(2018) Luis Solans et al.   Mucosal Immunology

Sustained protective immunity against Bordetella pertussis nasal colonization by intranasal immunization with a vaccine-adjuvant combination that induces IL-17-secreting TRM cells

(2018) Aideen C. Allen et al.   Mucosal Immunology

Induction and maintenance of a phenotypically heterogeneous lung tissue-resident CD4+ T cell population following BCG immunisation

(2018) Naomi C. Bull et al.   VACCINE

CD4 TRM Cells Following Infection and Immunization: Implications for More Effective Vaccine Design

(2018) Mieszko M. Wilk et al.   Frontiers in Immunology

PERISCOPE: road towards effective control of pertussis

(2018) Dimitri A. Diavatopoulos et al.   LANCET INFECTIOUS DISEASES

Enhanced protection conferred by mucosal BCG vaccination associates with presence of antigen-specific lung tissue-resident PD-1+ KLRG1− CD4+ T cells

(2018) N. C. Bull et al.   Mucosal Immunology

Lung CD4 Tissue-Resident Memory T Cells Mediate Adaptive Immunity Induced by Previous Infection of Mice withBordetella pertussis

(2017) Mieszko M. Wilk et al.   JOURNAL OF IMMUNOLOGY

Live Attenuated Pertussis Vaccine BPZE1 Protects Baboons Against Bordetella pertussis Disease and Infection

(2017) Camille Locht et al.   JOURNAL OF INFECTIOUS DISEASES

Bordetella Pertussis virulence factors in the continuing evolution of whooping cough vaccines for improved performance

(2017) Dorji Dorji et al.   MEDICAL MICROBIOLOGY AND IMMUNOLOGY

Outer Membrane Vesicles (OMV)-based and Proteomics-driven Antigen Selection Identifies Novel Factors Contributing toBordetella pertussisAdhesion to Epithelial Cells

(2017) Gianmarco Gasperini et al.   MOLECULAR & CELLULAR PROTEOMICS

Regionally compartmentalized resident memory T cells mediate naturally acquired protection against pneumococcal pneumonia

(2017) N MS Smith et al.   Mucosal Immunology

Airway T cells protect against RSV infection in the absence of antibody

(2017) E Kinnear et al.   Mucosal Immunology

Molecular and cellular signatures underlying superior immunity against Bordetella pertussis upon pulmonary vaccination

(2017) R HM Raeven et al.   Mucosal Immunology

Addition of a TLR7 agonist to an acellular pertussis vaccine enhances Th1 and Th17 responses and protective immunity in a mouse model

(2017) Alicja Misiak et al.   VACCINE

Country-level predictors of vaccination coverage and inequalities in Gavi-supported countries

(2017) Catherine Arsenault et al.   VACCINE

What Is Wrong with Pertussis Vaccine Immunity?

(2017) Nicolas Burdin et al.   Cold Spring Harbor Perspectives in Biology

Human Tissue-Resident Memory T Cells Are Defined by Core Transcriptional and Functional Signatures in Lymphoid and Mucosal Sites

(2017) Brahma V. Kumar et al.   Cell Reports

Follicular Helper T Cells

(2016) Carola G. Vinuesa et al.   Annual Review of Immunology

Investigating the pertussis resurgence in England and Wales, and options for future control

(2016) Yoon Hong Choi et al.   BMC Medicine

Th1 versus Th2 T cell polarization by whole-cell and acellular childhood pertussis vaccines persists upon re-immunization in adolescence and adulthood

(2016) Tara Bancroft et al.   CELLULAR IMMUNOLOGY

Assessing the Evidence for Maternal Pertussis Immunization: A Report From the Bill & Melinda Gates Foundation Symposium on Pertussis Infant Disease Burden in Low- and Lower-Middle-Income Countries

(2016) Ajoke Sobanjo-ter Meulen et al.   CLINICAL INFECTIOUS DISEASES

Airway Memory CD4 + T Cells Mediate Protective Immunity against Emerging Respiratory Coronaviruses

(2016) Jincun Zhao et al.   IMMUNITY

Bordetella pertussis epidemiology and evolution in the light of pertussis resurgence

(2016) Katie L. Sealey et al.   INFECTION GENETICS AND EVOLUTION

IL-17–Producing Innate and Pathogen-Specific Tissue Resident Memory γδ T Cells Expand in the Lungs ofBordetella pertussis–Infected Mice

(2016) Alicja Misiak et al.   JOURNAL OF IMMUNOLOGY

Vaccine-induced Th17 cells are established as resident memory cells in the lung and promote local IgA responses

(2016) D Christensen et al.   Mucosal Immunology

Subunit vaccine H56/CAF01 induces a population of circulating CD4 T cells that traffic into the Mycobacterium tuberculosis-infected lung

(2016) J S Woodworth et al.   Mucosal Immunology

Waning Tdap Effectiveness in Adolescents

(2016) Nicola P. Klein et al.   PEDIATRICS

Characterization of the immune response induced by pertussis OMVs-based vaccine

(2016) D. Bottero et al.   VACCINE

Pertussis vaccines: WHO position paper, August 2015—Recommendations

(2016)   VACCINE

Mucosal BCG Vaccination Induces Protective Lung-Resident Memory T Cell Populations against Tuberculosis

(2016) Carolina Perdomo et al.   mBio

One Dose of Staphylococcus aureus 4C-Staph Vaccine Formulated with a Novel TLR7-Dependent Adjuvant Rapidly Protects Mice through Antibodies, Effector CD4+ T Cells, and IL-17A

(2016) Francesca Mancini et al.   PLoS One

Transcriptome signature for dampened Th2 dominance in acellular pertussis vaccine-induced CD4+ T cell responses through TLR4 ligation

(2016) Jolanda Brummelman et al.   Scientific Reports

Novel adjuvant Alum-TLR7 significantly potentiates immune response to glycoconjugate vaccines

(2016) Cecilia Buonsanti et al.   Scientific Reports

Bordetella pertussis outer membrane vesicle vaccine confers equal efficacy in mice with milder inflammatory responses compared to a whole-cell vaccine

(2016) René H. M. Raeven et al.   Scientific Reports

Asymptomatic transmission and the resurgence of Bordetella pertussis

(2015) Benjamin M. Althouse et al.   BMC Medicine

Comparison of Three Whole-Cell Pertussis Vaccines in the Baboon Model of Pertussis

(2015) Jason M. Warfel et al.   Clinical and Vaccine Immunology

TLR9 and STING agonists synergistically induce innate and adaptive type-II IFN

(2015) Burcu Temizoz et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Airway-Resident Memory CD8 T Cells Provide Antigen-Specific Protection against Respiratory Virus Challenge through Rapid IFN-γ Production

(2015) Sean R. McMaster et al.   JOURNAL OF IMMUNOLOGY

Cutting Edge: CD69 Interference with Sphingosine-1-Phosphate Receptor Function Regulates Peripheral T Cell Retention

(2015) Laura K. Mackay et al.   JOURNAL OF IMMUNOLOGY

Immunoproteomic Profiling of Bordetella pertussis Outer Membrane Vesicle Vaccine Reveals Broad and Balanced Humoral Immunogenicity

(2015) René H. M. Raeven et al.   JOURNAL OF PROTEOME RESEARCH

Divergent behavior of mucosal memory T cells

(2015) O H Pham et al.   Mucosal Immunology

Outer-membrane vesicles from Gram-negative bacteria: biogenesis and functions

(2015) Carmen Schwechheimer et al.   NATURE REVIEWS MICROBIOLOGY

Vaccine composition formulated with a novel TLR7-dependent adjuvant induces high and broad protection againstStaphylococcus aureus

(2015) Fabio Bagnoli et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Pertactin negative Bordetella pertussis demonstrates higher fitness under vaccine selection pressure in a mixed infection model

(2015) Azadeh Safarchi et al.   VACCINE

Modulation of the CD4+ T cell response after acellular pertussis vaccination in the presence of TLR4 ligation

(2015) Jolanda Brummelman et al.   VACCINE

Vaccine Adjuvant Systems containing monophosphoryl lipid A and QS-21 induce strong humoral and cellular immune responses against hepatitis B surface antigen which persist for at least 4 years after vaccination

(2015) Geert Leroux-Roels et al.   VACCINE

A Change in Vaccine Efficacy and Duration of Protection Explains Recent Rises in Pertussis Incidence in the United States

(2015) Manoj Gambhir et al.   PLoS Computational Biology

Roads to the development of improved pertussis vaccines paved by immunology

(2015) Jolanda Brummelman et al.   Pathogens and Disease

Pulmonary Mycobacterium bovis BCG Vaccination Confers Dose-Dependent Superior Protection Compared to That of Subcutaneous Vaccination

(2014) Nacho Aguilo et al.   Clinical and Vaccine Immunology

Pertactin-Negative Bordetella pertussis Strains: Evidence for a Possible Selective Advantage

(2014) S. W. Martin et al.   CLINICAL INFECTIOUS DISEASES

Bordetella pertussisfimbriae (Fim): relevance for vaccines

(2014) Andrew R Gorringe et al.   Expert Review of Vaccines

TheBordetellaAdenylate Cyclase Repeat-in-Toxin (RTX) Domain Is Immunodominant and Elicits Neutralizing Antibodies

(2014) Xianzhe Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Adenylate Cyclase Toxin Subverts Phagocyte Function by RhoA Inhibition and Unproductive Ruffling

(2014) J. Kamanova et al.   JOURNAL OF IMMUNOLOGY

Cutting Edge: Inflammasome Activation by Alum and Alum's Adjuvant Effect Are Mediated by NLRP3

(2014) H. Li et al.   JOURNAL OF IMMUNOLOGY

CD4+ T Cells from Human Neonates and Infants Are Poised Spontaneously To Run a Nonclassical IL-4 Program

(2014) K. Hebel et al.   JOURNAL OF IMMUNOLOGY

Pertussis Pathogenesis--What We Know and What We Don't Know

(2014) E. L. Hewlett et al.   JOURNAL OF INFECTIOUS DISEASES

Pertussis Vaccine Trials in the 1990s

(2014) L. C. Lambert   JOURNAL OF INFECTIOUS DISEASES

A major population of mucosal memory CD4+ T cells, coexpressing IL-18Rα and DR3, display innate lymphocyte functionality

(2014) P Holmkvist et al.   Mucosal Immunology

A critical role for the TLR signaling adapter Mal in alveolar macrophage-mediated protection against Bordetella pertussis

(2014) N J Bernard et al.   Mucosal Immunology

A novel TLR2 agonist from Bordetella pertussis is a potent adjuvant that promotes protective immunity with an acellular pertussis vaccine

(2014) A Dunne et al.   Mucosal Immunology

A Phase I Clinical Study of a Live Attenuated Bordetella pertussis Vaccine - BPZE1; A Single Centre, Double-Blind, Placebo-Controlled, Dose-Escalating Study of BPZE1 Given Intranasally to Healthy Adult Male Volunteers

(2014) Rigmor Thorstensson et al.   PLoS One

Molecular Signatures of the Evolving Immune Response in Mice following a Bordetella pertussis Infection

(2014) René H. M. Raeven et al.   PLoS One

c-di-GMP Enhances Protective Innate Immunity in a Murine Model of Pertussis

(2014) Shokrollah Elahi et al.   PLoS One

Unraveling the challenges of pertussis

(2014) K. M. Edwards   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Resident memory CD8 T cells trigger protective innate and adaptive immune responses

(2014) J. M. Schenkel et al.   SCIENCE

A local macrophage chemokine network sustains protective tissue-resident memory CD4 T cells

(2014) N. Iijima et al.   SCIENCE

Rational design of small molecules as vaccine adjuvants

(2014) T. Y.- H. Wu et al.   Science Translational Medicine

Acellular pertussis vaccine based on outer membrane vesicles capable of conferring both long-lasting immunity and protection against different strain genotypes

(2014) María Emilia Gaillard et al.   VACCINE

IgG Subclasses and Allotypes: From Structure to Effector Functions

(2014) Gestur Vidarsson et al.   Frontiers in Immunology

Prevalence and Molecular Characterization of Pertactin-Deficient Bordetella pertussis in the United States

(2013) L. C. Pawloski et al.   Clinical and Vaccine Immunology

Adjuvants containing natural and synthetic Toll-like receptor 4 ligands

(2013) Gregory C Ireton et al.   Expert Review of Vaccines

Toll-like receptor 4 orchestrates neutrophil recruitment into airways during the first hours of Bordetella pertussis infection

(2013) Griselda Moreno et al.   MICROBES AND INFECTION

The cGAS-STING Pathway for DNA Sensing

(2013) T. Sam Xiao et al.   MOLECULAR CELL

Sensing and alarm function of resident memory CD8+ T cells

(2013) Jason M Schenkel et al.   NATURE IMMUNOLOGY

Comparative Effectiveness of Acellular Versus Whole-Cell Pertussis Vaccines in Teenagers

(2013) N. P. Klein et al.   PEDIATRICS

Genetic Analysis of Bordetella pertussis Isolates from the 2008–2010 Pertussis Epidemic in Japan

(2013) Yusuke Miyaji et al.   PLoS One

Acellular pertussis vaccines protect against disease but fail to prevent infection and transmission in a nonhuman primate model

(2013) J. M. Warfel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A CpG-containing oligodeoxynucleotide adjuvant for acellular pertussis vaccine improves the protective response againstBordetella pertussis

(2013) Catpagavalli Asokanathan et al.   Human Vaccines & Immunotherapeutics

Relative Contribution of Th1 and Th17 Cells in Adaptive Immunity to Bordetella pertussis: Towards the Rational Design of an Improved Acellular Pertussis Vaccine

(2013) Pádraig J. Ross et al.   PLoS Pathogens

BothCD4+andCD8+Lymphocytes Participate in the IFN-γ Response to Filamentous Hemagglutinin fromBordetella pertussisin Infants, Children, and Adults

(2012) Violette Dirix et al.   Clinical & Developmental Immunology

The vaccine adjuvant alum inhibits IL-12 by promoting PI3 kinase signaling while chitosan does not inhibit IL-12 and enhances Th1 and Th17 responses

(2012) Andres Mori et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Number and Order of Whole Cell Pertussis Vaccines in Infancy and Disease Protection

(2012) Sarah L. Sheridan et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

California Pertussis Epidemic, 2010

(2012) Kathleen Winter et al.   JOURNAL OF PEDIATRICS

The Bordetella pertussis model of exquisite gene control by the global transcription factor BvgA

(2012) K. B. Decker et al.   MICROBIOLOGY-SGM

Bordetella pertussis infection induces a mucosal IL-17 response and long-lived Th17 and Th1 immune memory cells in nonhuman primates

(2012) J M Warfel et al.   Mucosal Immunology

Immunity to the respiratory pathogen Bordetella pertussis

(2012) R Higgs et al.   Mucosal Immunology

STING and the innate immune response to nucleic acids in the cytosol

(2012) Dara L Burdette et al.   NATURE IMMUNOLOGY

Waning Protection after Fifth Dose of Acellular Pertussis Vaccine in Children

(2012) Nicola P. Klein et al.   NEW ENGLAND JOURNAL OF MEDICINE

STING Specifies IRF3 Phosphorylation by TBK1 in the Cytosolic DNA Signaling Pathway

(2012) Y. Tanaka et al.   Science Signaling

Development of an AS04-Adjuvanted HPV Vaccine with the Adjuvant System Approach

(2011) Nathalie Garçon et al.   BIODRUGS

CpG DNA as a vaccine adjuvant

(2011) Christian Bode et al.   Expert Review of Vaccines

Cutting Edge: Tissue-Retentive Lung Memory CD4 T Cells Mediate Optimal Protection to Respiratory Virus Infection

(2011) J. R. Teijaro et al.   JOURNAL OF IMMUNOLOGY

Attenuated Bordetella pertussis Vaccine Candidate BPZE1 Promotes Human Dendritic Cell CCL21-Induced Migration and Drives a Th1/Th17 Response

(2011) G. Fedele et al.   JOURNAL OF IMMUNOLOGY

Possible allelic structure of IgG2a and IgG2c in mice

(2011) Zhiping Zhang et al.   MOLECULAR IMMUNOLOGY

STING is a direct innate immune sensor of cyclic di-GMP

(2011) Dara L. Burdette et al.   NATURE

Outer membrane vesicles obtained from Bordetella pertussis Tohama expressing the lipid A deacylase PagL as a novel acellular vaccine candidate

(2011) Cristian J.A. Asensio et al.   VACCINE

Different IgG-subclass distributions after whole-cell and acellular pertussis infant primary vaccinations in healthy and pertussis infected children

(2011) Lotte H. Hendrikx et al.   VACCINE

Immune mechanisms of protection: can adjuvants rise to the challenge?

(2010) Amy S McKee et al.   BMC BIOLOGY

A Live, AttenuatedBordetella pertussisVaccine Provides Long-Term Protection against Virulent Challenge in a Murine Model

(2010) Ciaran M. Skerry et al.   Clinical and Vaccine Immunology

Antibody Response Patterns to Bordetella pertussis Antigens in Vaccinated (Primed) and Unvaccinated (Unprimed) Young Children with Pertussis

(2010) J. D. Cherry et al.   Clinical and Vaccine Immunology

Correlates of Protection Induced by Vaccination

(2010) S. A. Plotkin   Clinical and Vaccine Immunology

The role of Th17 cytokines in primary mucosal immunity

(2010) Jay K. Kolls et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Vaccine Adjuvants: Putting Innate Immunity to Work

(2010) Robert L. Coffman et al.   IMMUNITY

Dynamic T cell migration program provides resident memory within intestinal epithelium

(2010) David Masopust et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Inflammasome Activation by Adenylate Cyclase Toxin Directs Th17 Responses and Protection against Bordetella pertussis

(2010) A. Dunne et al.   JOURNAL OF IMMUNOLOGY

Insight into Evolution of Bordetella pertussis from Comparative Genomic Analysis: Evidence of Vaccine-Driven Selection

(2010) Sophie Octavia et al.   MOLECULAR BIOLOGY AND EVOLUTION

T- and B-Cell-Mediated Protection Induced by Novel, Live Attenuated Pertussis Vaccine in Mice. Cross Protection against Parapertussis

(2010) Pascal Feunou Feunou et al.   PLoS One

Long-term immunity against pertussis induced by a single nasal administration of live attenuated B. pertussis BPZE1

(2010) Pascal Feunou Feunou et al.   VACCINE

Immunotherapeutic applications of CpG oligodeoxynucleotide TLR9 agonists

(2009) Jörg Vollmer et al.   ADVANCED DRUG DELIVERY REVIEWS

Interleukin-10: new perspectives on an old cytokine

(2009) David M. Mosser et al.   IMMUNOLOGICAL REVIEWS

Bordetellaevades the host immune system by inducing IL-10 through a type III effector, BopN

(2009) Kanna Nagamatsu et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Cutting Edge: Lung Mucosal Th17-Mediated Responses Induce Polymeric Ig Receptor Expression by the Airway Epithelium and Elevate Secretory IgA Levels

(2009) Z. Jaffar et al.   JOURNAL OF IMMUNOLOGY

CD11c+CD8 + Dendritic Cells Promote Protective Immunity to Respiratory Infection with Bordetella pertussis

(2009) P. J. Dunne et al.   JOURNAL OF IMMUNOLOGY

Memory T cells in nonlymphoid tissue that provide enhanced local immunity during infection with herpes simplex virus

(2009) Thomas Gebhardt et al.   NATURE IMMUNOLOGY

First report and detailed characterization of B. pertussis isolates not expressing pertussis toxin or pertactin

(2009) V. Bouchez et al.   VACCINE

The role of Toll-like receptor-4 in pertussis vaccine-induced immunity

(2008) Sander Banus et al.   BMC IMMUNOLOGY

Induction, function and regulation of IL-17-producing T cells

(2008) Kingston H. G. Mills   EUROPEAN JOURNAL OF IMMUNOLOGY

The Nlrp3 inflammasome is critical for aluminium hydroxide-mediated IL-1β secretion but dispensable for adjuvant activity

(2008) Luigi Franchi et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Role of Neutrophils in Response to Bordetella pertussis Infection in Mice

(2008) C. Andreasen et al.   INFECTION AND IMMUNITY

Pertussis Toxin Inhibits Early Chemokine Production To Delay Neutrophil Recruitment in Response to Bordetella pertussis Respiratory Tract Infection in Mice

(2008) C. Andreasen et al.   INFECTION AND IMMUNITY

STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling

(2008) Hiroki Ishikawa et al.   NATURE

Protective activity of the Bordetella pertussis BrkA autotransporter in the murine lung colonization model

(2008) Nico Marr et al.   VACCINE

Outer membrane vesicles as acellular vaccine against pertussis

(2008) Roy Roberts et al.   VACCINE