Impact of investigational microbiota therapeutic RBX2660 on the gut microbiome and resistome revealed by a placebo-controlled clinical trial
出版年份 2020 全文链接
标题
Impact of investigational microbiota therapeutic RBX2660 on the gut microbiome and resistome revealed by a placebo-controlled clinical trial
作者
关键词
-
出版物
Microbiome
Volume 8, Issue 1, Pages -
出版商
Springer Science and Business Media LLC
发表日期
2020-08-31
DOI
10.1186/s40168-020-00907-9
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Restoration of Bacterial Microbiome Composition and Diversity Among Treatment Responders in a Phase 2 Trial of Rbx2660—An Investigational Microbiome Restoration Therapeutic
- (2019) Ken F Blount et al. Open Forum Infectious Diseases
- The incremental cost of infections associated with multidrug-resistant organisms in the inpatient hospital setting-A national estimate
- (2019) Kenton J. Johnston et al. HEALTH SERVICES RESEARCH
- Interactive Tree Of Life (iTOL) v4: recent updates and new developments
- (2019) Ivica Letunic et al. NUCLEIC ACIDS RESEARCH
- Meta-omics analysis of elite athletes identifies a performance-enhancing microbe that functions via lactate metabolism
- (2019) Jonathan Scheiman et al. NATURE MEDICINE
- Fecal Microbial Transplantation and Its Potential Application in Cardiometabolic Syndrome
- (2019) Avner Leshem et al. Frontiers in Immunology
- Drug-Resistant E. coli Bacteremia Transmitted by Fecal Microbiota Transplant
- (2019) Zachariah DeFilipp et al. NEW ENGLAND JOURNAL OF MEDICINE
- Neuroinflammation and the Gut Microbiota: Possible Alternative Therapeutic Targets to Counteract Alzheimer’s Disease?
- (2019) Milica Cerovic et al. Frontiers in Aging Neuroscience
- Corrigendum: The Role of Fecal Microbiota Transplantation in Reducing Intestinal Colonization With Antibiotic-Resistant Organisms: The Current Landscape and Future Directions
- (2019) Michael H Woodworth et al. Open Forum Infectious Diseases
- Tapering Courses of Oral Vancomycin Induce Persistent Disruption of the Microbiota That Provide Colonization Resistance to Clostridium difficile and Vancomycin-Resistant Enterococci in Mice
- (2018) Myreen E. Tomas et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Results From a Randomized, Placebo-Controlled Clinical Trial of a RBX2660—A Microbiota-Based Drug for the Prevention of Recurrent Clostridium difficile Infection
- (2018) Erik R Dubberke et al. CLINICAL INFECTIOUS DISEASES
- Safety and efficacy of encapsulated fecal microbiota transplantation for recurrent Clostridium difficile infection
- (2018) Umair Iqbal et al. EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY
- Clinical Application and Potential of Fecal Microbiota Transplantation
- (2018) R.E. Ooijevaar et al. Annual Review of Medicine
- Genus-Wide Assessment of Antibiotic Resistance in Lactobacillus spp.
- (2018) Ilenia Campedelli et al. APPLIED AND ENVIRONMENTAL MICROBIOLOGY
- Recurrent Clostridium difficile Infection: Risk Factors, Treatment, and Prevention
- (2018) Jung Hoon Song et al. Gut and Liver
- Fecal microbiota transplantation shortens the colonization period and allows the re-entry of patients carrying carbapenamase-producing bacteria into medical care facilities
- (2018) Nadia SAÏDANI et al. INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS
- Species-level functional profiling of metagenomes and metatranscriptomes
- (2018) Eric A. Franzosa et al. NATURE METHODS
- Effect of Fidaxomicin versus Vancomycin on Susceptibility to Intestinal Colonization with Vancomycin-Resistant Enterococci and Klebsiella pneumoniae in Mice
- (2016) Abhishek Deshpande et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- A two-part mixed-effects model for analyzing longitudinal microbiome compositional data
- (2016) Eric Z. Chen et al. BIOINFORMATICS
- Faecal carriage of antibiotic resistant Escherichia coli in asymptomatic children and associations with primary care antibiotic prescribing: a systematic review and meta-analysis
- (2016) Ashley Bryce et al. BMC INFECTIOUS DISEASES
- Fecal Microbial Transplants Reduce Antibiotic-resistant Genes in Patients With RecurrentClostridium difficileInfection
- (2016) Braden Millan et al. CLINICAL INFECTIOUS DISEASES
- Does the donor matter? Donor vs patient effects in the outcome of a next-generation microbiota-based drug trial for recurrent Clostridium difficile infection
- (2016) Arnab Ray et al. Future Microbiology
- Short- and long-term effects of oral vancomycin on the human intestinal microbiota
- (2016) Sandrine Isaac et al. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
- Interconnected microbiomes and resistomes in low-income human habitats
- (2016) Erica C. Pehrsson et al. NATURE
- CARD 2017: expansion and model-centric curation of the comprehensive antibiotic resistance database
- (2016) Baofeng Jia et al. NUCLEIC ACIDS RESEARCH
- Clinical epidemiology of vancomycin-resistant Enterococcus gallinarum and Enterococcus casseliflavus bloodstream infections
- (2016) Nicholas S. Britt et al. Journal of Global Antimicrobial Resistance
- Fecal Microbiota Transplantation and Its Usage in Neuropsychiatric Disorders
- (2016) Alper Evrensel et al. Clinical Psychopharmacology and Neuroscience
- Clostridium difficile infection
- (2016) Wiep Klaas Smits et al. Nature Reviews Disease Primers
- Roary: rapid large-scale prokaryote pan genome analysis
- (2015) Andrew J. Page et al. BIOINFORMATICS
- Safety and Durability of RBX2660 (Microbiota Suspension) for RecurrentClostridium difficileInfection: Results of the PUNCH CD Study
- (2015) Robert Orenstein et al. CLINICAL INFECTIOUS DISEASES
- Assessment of Reproducibility of Matrix-Assisted Laser Desorption Ionization–Time of Flight Mass Spectrometry for Bacterial and Yeast Identification
- (2015) Lars F. Westblade et al. JOURNAL OF CLINICAL MICROBIOLOGY
- High-Specificity Targeted Functional Profiling in Microbial Communities with ShortBRED
- (2015) James Kaminski et al. PLoS Computational Biology
- Inexpensive Multiplexed Library Preparation for Megabase-Sized Genomes
- (2015) Michael Baym et al. PLoS One
- Prokka: rapid prokaryotic genome annotation
- (2014) T. Seemann BIOINFORMATICS
- Trimmomatic: a flexible trimmer for Illumina sequence data
- (2014) Anthony M. Bolger et al. BIOINFORMATICS
- Fecal Microbiota Transplant for Relapsing Clostridium difficile Infection Using a Frozen Inoculum From Unrelated Donors: A Randomized, Open-Label, Controlled Pilot Study
- (2014) Ilan Youngster et al. CLINICAL INFECTIOUS DISEASES
- Evaluation of the Bruker Biotyper and VITEK MS MALDI-TOF MS systems for the identification of unusual and/or difficult-to-identify microorganisms isolated from clinical specimens
- (2014) E. McElvania TeKippe et al. EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES
- Improved annotation of antibiotic resistance determinants reveals microbial resistomes cluster by ecology
- (2014) Molly K Gibson et al. ISME Journal
- Fecal microbiota transplantation as therapy for inflammatory bowel disease: A systematic review and meta-analysis
- (2014) Ruben J. Colman et al. Journal of Crohns & Colitis
- Is fecal microbiota transplantation (FMT) an effective treatment for patients with functional gastrointestinal disorders (FGID)?
- (2014) D. M. Pinn et al. NEUROGASTROENTEROLOGY AND MOTILITY
- The Comprehensive Antibiotic Resistance Database
- (2013) Andrew G. McArthur et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- QUAST: quality assessment tool for genome assemblies
- (2013) Alexey Gurevich et al. BIOINFORMATICS
- Intestinal Microbiota Containing Barnesiella Species Cures Vancomycin-Resistant Enterococcus faecium Colonization
- (2013) Carles Ubeda et al. INFECTION AND IMMUNITY
- Impact of oral vancomycin on gut microbiota, bile acid metabolism, and insulin sensitivity
- (2013) Anne Vrieze et al. JOURNAL OF HEPATOLOGY
- SPAdes: A New Genome Assembly Algorithm and Its Applications to Single-Cell Sequencing
- (2012) Anton Bankevich et al. JOURNAL OF COMPUTATIONAL BIOLOGY
- Diversity, stability and resilience of the human gut microbiota
- (2012) Catherine A. Lozupone et al. NATURE
- Metagenomic microbial community profiling using unique clade-specific marker genes
- (2012) Nicola Segata et al. NATURE METHODS
- Fast gapped-read alignment with Bowtie 2
- (2012) Ben Langmead et al. NATURE METHODS
- Fast Identification and Removal of Sequence Contamination from Genomic and Metagenomic Datasets
- (2011) Robert Schmieder et al. PLoS One
- Metagenomic biomarker discovery and explanation
- (2011) Nicola Segata et al. GENOME BIOLOGY
- Commensal Escherichia coli of healthy humans: a reservoir for antibiotic-resistance determinants
- (2010) J. K. Bailey et al. JOURNAL OF MEDICAL MICROBIOLOGY
- A human gut microbial gene catalogue established by metagenomic sequencing
- (2010) Junjie Qin et al. NATURE
- FastTree 2 – Approximately Maximum-Likelihood Trees for Large Alignments
- (2010) Morgan N. Price et al. PLoS One
- The Sequence Alignment/Map format and SAMtools
- (2009) H. Li et al. BIOINFORMATICS
- Interspecies Signaling between Veillonella atypica and Streptococcus gordonii Requires the Transcription Factor CcpA
- (2009) B. P. Johnson et al. JOURNAL OF BACTERIOLOGY
- Both Oral Metronidazole and Oral Vancomycin Promote Persistent Overgrowth of Vancomycin-Resistant Enterococci during Treatment of Clostridium difficile-Associated Disease
- (2008) W. N. Al-Nassir et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started