Review
Nutrition & Dietetics
Sharlize Pedroza Matute, Sasitaran Iyavoo
Summary: The gut microbiota is closely related to the health and disease state of the human body, and can be influenced by factors such as diet, exercise, and mental health. Understanding the impact of lifestyle on the gut microbiota can lead to personalized advice for preventing and improving dysbiosis. However, providing effective advice relies on accurate research and assessment methods.
FRONTIERS IN NUTRITION
(2023)
Article
Gastroenterology & Hepatology
Barbara Olendzki, Vanni Bucci, Caitlin Cawley, Rene Maserati, Margaret McManus, Effie Olednzki, Camilla Madziar, David Chiang, Doyle Ward, Randall Pellish, Christine Foley, Shakti Bhattarai, Beth A. McCormick, Ana Maldonado-Contreras
Summary: This study aims to investigate the impact of specific foods on the intestinal microbiome in patients with IBD and explore the interactions between diet and immunity to provide personalized nutrition guidance for IBD patients with dysbiosis-related conditions.
Review
Nutrition & Dietetics
Eleuterio A. Sanchez Romero, Erika Melendez Oliva, Jose Luis Alonso Perez, Sebastian Martin Perez, Silvia Turroni, Lorenzo Marchese, Jorge Hugo Villafane
Summary: This study aimed to review the association between gut microbiome and pain in OA patients and found only three out of 2084 studies supported a relationship, but the results were not conclusive. It also highlighted the lack of high-quality studies and significant technique disparities, making it impossible to draw firm conclusions on the topic.
Review
Gastroenterology & Hepatology
Blaine Caslin, Kailey Mohler, Shreya Thiagarajan, Esther Melamed
Summary: Alcohol may have complex effects on autoimmune diseases, with potential pro-inflammatory and anti-inflammatory properties. These effects may be related to factors such as the dose, duration, type, cultural background, and sex of alcohol consumption.
Article
Microbiology
Bassam Abomoelak, Veronica Pemberton, Chirajyoti Deb, Stephani Campion, Michelle Vinson, Jennifer Mauck, Joseph Manipadam, Sailendharan Sudakaran, Samit Patel, Miguel Saps, Hesham A. El Enshasy, Theodoros Varzakas, Devendra Mehta
Summary: This prospective longitudinal study revealed distinct differences in gut microbiome between pediatric patients with functional abdominal pain disorders (FAPDs) and healthy controls, with variations observed not only in bacterial populations but also in diversity levels. The severity of symptoms in patients was found to be correlated with the gut microbiome, highlighting a potential relationship between the two. Additionally, the Faecalibacterium/Bacteroides ratio may serve as a promising diagnostic biomarker for FAPDs.
Review
Nutrition & Dietetics
Ryan Leung, Mihai Covasa
Summary: This article reviews the role of gut bacteria in taste perception and functions, and discusses how intestinal dysbiosis can alter taste preference and food consumption.
Review
Microbiology
Benjamin H. Levine, Jessica M. Hoffman
Summary: The human gut contains trillions of microbes that play a crucial role in various health functions, but they are also associated with numerous diseases. Microbiome transplants offer a potential solution to mitigate these health issues caused by the gut microbiome. This article provides an overview of the gut's functional relationships, highlights the diseases directly affected, and explores the history and applications of microbiome transplants in various diseases.
Review
Biochemistry & Molecular Biology
Laura Bozomitu, Ingrith Miron, Anca Adam Raileanu, Ancuta Lupu, Gabriela Paduraru, Florin Mihai Marcu, Ana Maria Laura Buga, Daniela Carmen Rusu, Felicia Dragan, Vasile Valeriu Lupu
Summary: This article reviews the composition and function of the human gastrointestinal microbiome in healthy individuals, as well as its role in the pathogenesis of different digestive disorders. It also highlights the potential of manipulating the gut microbiota as a therapeutic option for treating gastrointestinal diseases.
Review
Biochemistry & Molecular Biology
Kunika, Norbert Y. Frey, Ashraf Rangrez
Summary: Recent technological advancements have increased our understanding of the human microbiome, which plays a role in both health and disease progression, including cancer and heart disease. The microbiome may potentially be targeted in cancer therapy to improve treatment effectiveness. Additionally, the altered microbiome composition caused by cancer treatment is linked to long-term effects and can lead to gastrointestinal toxicity. The relationship between the microbiome and cardiac diseases in cancer patients following therapy is poorly understood.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Biochemistry & Molecular Biology
Zehavit Nitzan, Elsebeth Staun-Ram, Anat Volkowich, Ariel Miller, Serge Nataf
Summary: Microbiome dysbiosis is implicated in immune-mediated disorders, including multiple sclerosis. This study characterizes the MS-associated gut microbiome in Israeli populations and identifies associations with demographic, dietary, and clinical features. The findings suggest that alterations in the microbiota composition are related to disease progression, gender differences, and vitamin D-mediated immunological effects recognized in MS.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Review
Gastroenterology & Hepatology
Mi Young Lim, Young-Do Nam
Summary: As the proportion of older people in the population increases, it is important to find ways to support healthy aging. The gut microbiome has been identified as a potential factor in aging-related diseases and is a target for improving health in older individuals. In this article, the relationship between the gut microbiome and chronological age in adults is discussed, as well as the features of the gut microbiome associated with unhealthy aging. The effects of microbiome-targeted interventions, such as dietary patterns and consumption of probiotics, prebiotics, and synbiotics, on modulating the gut microbiome composition and promoting healthy aging are also described. Further research is needed to understand the mechanisms of gut microbiome-induced aging complications and develop personalized microbiome-based strategies for reducing frailty severity or preventing frailty in older adults.
Review
Medicine, Research & Experimental
Kunal Dixit, Diptaraj Chaudhari, Dhiraj Dhotre, Yogesh Shouche, Sunil Saroj
Summary: The human microbiome is a complex and dynamic ecosystem, with dysbiosis leading to various pathological conditions. The gut microbiome starts to develop before birth, influenced by factors such as birth mode, lifestyle, dietary practices, and medications. Restoring the dysbiotic microbiome has shown promise as a therapeutic approach.
Review
Biotechnology & Applied Microbiology
Shaodong Wei, Martin Iain Bahl, Simon Mark Dahl Baunwall, Christian Lodberg Hvas, Tine Rask Licht
Summary: This paper lists various types of dysbiosis indexes identified in the literature, introduces their methodology, categorizes them, and discusses their potential descriptive and clinical applications as well as their limitations. The focus is on the methodological approaches available to determine and quantify the dysbiosis condition, rather than on the implications of dysbiosis for disease.
APPLIED AND ENVIRONMENTAL MICROBIOLOGY
(2021)
Review
Immunology
Walaa K. Mousa, Fadia Chehadeh, Shannon Husband
Summary: The interaction between gut microbes and the immune system plays a crucial role in the development and treatment of systemic autoimmune diseases. Understanding how gut microbes can trigger or protect from these diseases can help us tackle them through dietary and lifestyle changes, microbiome-based therapies, identification of diagnostic biomarkers, and intervention with microbial population changes. Considering the microbiome signature as a key player in systemic autoimmune diseases holds promise in transforming these untreatable diseases into manageable or preventable ones.
FRONTIERS IN IMMUNOLOGY
(2022)
Article
Infectious Diseases
Yoowon Kwon, Young-Sun Cho, Yoo-Mi Lee, Seok-jin Kim, Jaewoong Bae, Su-Jin Jeong
Summary: This study evaluated the gut microbiome state in infants following systemic antibiotic treatment. The results showed that the composition of the gut microbiome in the antibiotic treatment group was altered, with increased relative abundance of Escherichia/Shigella and Bifidobacterium, and decreased relative abundance of Bacteroides. Additionally, the antibiotic treatment group had lower microbiome diversity. Long-term studies are needed to further understand the impact of antibiotics on the gut microbiome.
Article
Biotechnology & Applied Microbiology
Carolina Paduro, David A. Montero, Nayaret Chamorro, Leandro J. Carreno, Maricel Vidal, Roberto Vidal
Review
Nutrition & Dietetics
Fabien Magne, Martin Gotteland, Lea Gauthier, Alejandra Zazueta, Susana Pesoa, Paola Navarrete, Ramadass Balamurugan
Article
Immunology
David A. Montero, Felipe Del Canto, Juan C. Salazar, Sandra Cespedes, Leandro Cadiz, Mauricio Arenas-Salinas, Jose Reyes, Angel Onate, Roberto M. Vidal
Article
Microbiology
Alexia N. Torres, Nayaret Chamorro-Veloso, Priscila Costa, Leandro Cadiz, Felipe Del Canto, Sebastian A. Venegas, Mercedes Lopez Nitsche, Roberto F. Coloma-Rivero, David A. Montero, Roberto M. Vidal
Article
Multidisciplinary Sciences
Vicente Perez-Brocal, Fabien Magne, Susana Ruiz-Ruiz, Carolina A. Ponce, Rebeca Bustamante, Viviana San Martin, Mireya Gutierrez, Gianna Gatti, Sergio L. Vargas, Andres Moya
SCIENTIFIC REPORTS
(2020)
Review
Nutrition & Dietetics
Martin Gotteland, Karla Riveros, Naschla Gasaly, Constanza Carcamo, Fabien Magne, Gianella Liabeuf, Alejandra Beattie, Sebastian Rosenfeld
FRONTIERS IN NUTRITION
(2020)
Article
Medicine, General & Internal
Cecilia V. Tapia, Campos Marcia, Mora Ivone, Pozas Nadia, Morales Lesly, Guzman Camila, Aguilera Valentina, Ibarra Paula, Magne Fabien
Summary: A study compared saliva, nasal mid-turbinate swab, and nasopharyngeal swab samples in 112 ambulatory patients suspected of COVID-19, finding that while saliva samples had lower sensitivity for SARS-CoV-2 detection compared to NP swabs, they could be an interesting alternative sampling method when NP swabs cannot be collected.
FRONTIERS IN MEDICINE
(2021)
Article
Nutrition & Dietetics
Boopalan Ramasamy, Fabien Magne, Sujit Kumar Tripathy, Giriprasad Venugopal, Diptasree Mukherjee, Ramadass Balamurugan
Summary: In this study, specific bacterial species were found in vitamin D deficient patients, with or without KOA, indicating a potential association between gut microbiome composition, vitamin D, and knee osteoarthritis.
Article
Multidisciplinary Sciences
Susana A. Pesoa, Nestor Portela, Eduardo Fernandez, Osvaldo Elbarcha, Martin Gotteland, Fabien Magne
Summary: Accumulated evidence shows that genetic and environmental factors contribute to obesity, with gut microbiota playing a critical role in metabolism regulation and the development of chronic diseases. The study used high throughput sequencing to identify microbial differences in obese individuals from Argentina, US, and UK, revealing distinct microbiotypes and metabolic pathway signatures. This indicates that personalized strategies for managing obesity based on microbiome configuration could be promising.
SCIENTIFIC REPORTS
(2021)
Article
Immunology
Juliana Gonzalez, Jimena Soledad Cadona, Claudio Marcelo Zotta, Silvina Lavayen, Roberto Vidal, Nora Lia Padola, Andrea Mariel Sanso, Ana Victoria Bustamante
Summary: This study aimed to compare the genetic diversity of VTEC O157:H7 strains isolated from human disease cases in Argentina and Chile. The results showed that these strains mainly belonged to lineage I/II, associated with hypervirulent strains, and were categorized into the phylogroup E. Additionally, genetic diversity was observed among Argentinean and Chilean strains, particularly in relation to putative virulence determinants and nle profiles.
MICROBES AND INFECTION
(2022)
Article
Microbiology
Susana Ruiz-Ruiz, Carolina A. Ponce, Nicole Pesantes, Rebeca Bustamante, Gianna Gatti, Viviana San Martin, Mireya Gutierrez, Pamela Borquez, Sergio L. Vargas, Fabien Magne, Enrique J. Calderon, Vicente Perez-Brocal, Andres Moya
Summary: A new real-time PCR assay using SYBR Green has been developed for the detection of low levels of Pneumocystis jirovecii with higher sensitivity. This assay targets two regions simultaneously using two primer sets, and it has been found to be more rapid and simpler compared to the current nested-PCR methods. The new assay was able to detect P. jirovecii in samples that were negative for both rounds of nested-PCR, demonstrating its ability to detect low levels of the pathogen.
FRONTIERS IN MICROBIOLOGY
(2022)
Article
Microbiology
Dinka Ivulic, Ramon Rossello-Mora, Tomeu Viver, David A. Montero, Sonia Vidal, Francisco Aspee, Hector Hidalgo, Roberto Vidal
Summary: This study investigated the relationship between airborne and respiratory tract-associated bacterial diversity in broiler production systems. Results showed a decrease in coliforms in the air over time, but an increase was observed in week 3 due to litter management practices. There were distinct microbial communities in the air primarily associated with the Bacilli class, and the tracheal microbiome shifted from Escherichia coli/Shigella to Gallibacterium over the production cycle.
Article
Microbiology
Saurav Sarkar, Fabien Magne, Giriprasad Venugopal, Suvendu Purkait, Naresh V. R. Mutha, Rituparna Maiti, Prity Sharma, Balamurugan Ramadass
Summary: The study found that using manuka honey as a prebiotic treatment can improve clinical symptoms and nasal microbiome composition in patients with atrophic rhinitis. After treatment with manuka honey, endoscopic scores and clinical symptoms improved, with decreased inflammation, restoration of mucus glands, and increased expression of GPR43 in the nasal cavities.
Article
Biochemistry & Molecular Biology
Roberto M. Vidal, David A. Montero, Felipe Del Canto, Juan C. Salazar, Carolina Arellano, Alhejandra Alvarez, Nora L. Padola, Hernan Moscuzza, Analia Etcheverria, Daniel Fernandez, Victoria Velez, Mauro Garcia, Rocio Colello, Marcelo Sanz, Angel Onate
Summary: In this study, the safety and immunogenicity of a vaccine candidate against Shiga toxin-producing Escherichia coli (STEC) was evaluated. The vaccine, formulated with two chimeric proteins, was administered to pregnant cows in their third trimester of gestation. The results demonstrated that the vaccine is safe and immunogenic, suggesting the feasibility of vaccinating cows with it during late pregnancy.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Microbiology
Diego Zamorano, Dinka Ivulic, Tomeu Viver, Felipe Morales, Francisco Lopez-Kostner, Roberto M. Vidal
Summary: Anastomotic leakage (AL) is a common complication after colorectal surgery and the underlying mechanism is still not well understood. This study aimed to investigate the association between gut microbiota and colorectal AL development. Through analyzing tissue-associated microbiota using 16S rRNA sequencing, lower microbial diversity was observed in the AL group compared to non-leak anastomosis (NLA) group. The facultative anaerobic bacterium Gemella palaticanis showed high abundance and may be a potential marker for AL.