Acellular Pertussis Vaccines Induce Anti-pertactin Bactericidal Antibodies Which Drives the Emergence of Pertactin-Negative Strains

Neutralization of pertussis toxin by a single antibody prevents clinical pertussis in neonatal baboons

(2020) Annalee W. Nguyen et al.   Science Advances

Development and Standardization of a High-Throughput Bordetella pertussis Growth-Inhibition Assay

(2020) Anaïs Thiriard et al.   Frontiers in Microbiology

Immunization with whole cell but not acellular pertussis vaccines primes CD4 TRM cells that sustain protective immunity against nasal colonization with Bordetella pertussis

(2019) Mieszko M. Wilk et al.   Emerging Microbes & Infections

A review of complement sources used in serum bactericidal assays for evaluating immune responses to meningococcal ACWY conjugate vaccines

(2019) Jamie Findlow et al.   Human Vaccines & Immunotherapeutics

Pertactin-deficient Bordetella pertussis isolates: evidence of increased circulation in Europe, 1998 to 2015

(2019) Alex-Mikael Barkoff et al.   Eurosurveillance

Pertussis Prevention: Reasons for Resurgence, and Differences in the Current Acellular Pertussis Vaccines

(2019) Susanna Esposito et al.   Frontiers in Immunology

Updates on immunologic correlates of vaccine-induced protection

(2019) Stanley A. Plotkin   VACCINE

Surfaceome analysis of Australian epidemic Bordetella pertussis reveals potential vaccine antigens

(2019) Laurence Don Wai Luu et al.   VACCINE

Screening and Genomic Characterization of Filamentous Hemagglutinin-Deficient Bordetella pertussis

(2018) Michael R. Weigand et al.   INFECTION AND IMMUNITY

Characterization of Individual Human Antibodies That Bind Pertussis Toxin Stimulated by Acellular Immunization

(2018) Edith Acquaye-Seedah et al.   INFECTION AND IMMUNITY

Maternal Vaccination With a Monocomponent Pertussis Toxoid Vaccine Is Sufficient to Protect Infants in a Baboon Model of Whooping Cough

(2018) Parul Kapil et al.   JOURNAL OF INFECTIOUS DISEASES

Bordetella pertussis isolates vary in their interactions with human complement components

(2018) Charlotte Brookes et al.   Emerging Microbes & Infections

Whole-Cell or Acellular Pertussis Primary Immunizations in Infancy Determines Adolescent Cellular Immune Profiles

(2018) Saskia van der Lee et al.   Frontiers in Immunology

Th1/Th17 polarization persists following whole-cell pertussis vaccination despite repeated acellular boosters

(2018) Ricardo da Silva Antunes et al.   JOURNAL OF CLINICAL INVESTIGATION

Detection of opsonizing antibodies directed against a recently circulating Bordetella pertussis strain in paired plasma samples from symptomatic and recovered pertussis patients

(2018) Elise S. Hovingh et al.   Scientific Reports

PERISCOPE: road towards effective control of pertussis

(2018) Dimitri A. Diavatopoulos et al.   LANCET INFECTIOUS DISEASES

Pertussis disease and transmission and host responses: insights from the baboon model of pertussis

(2017) Marta V. Pinto et al.   JOURNAL OF INFECTION

An update of the global burden of pertussis in children younger than 5 years: a modelling study

(2017) Karene Hoi Ting Yeung et al.   LANCET INFECTIOUS DISEASES

Acquisition of C1 inhibitor by Bordetella pertussis virulence associated gene 8 results in C2 and C4 consumption away from the bacterial surface

(2017) Elise S. Hovingh et al.   PLoS Pathogens

Impact of age and vaccination history on long-term serological responses after symptomatic B. pertussis infection, a high dimensional data analysis

(2017) Inonge van Twillert et al.   Scientific Reports

Waning Tdap Effectiveness in Adolescents

(2016) Nicola P. Klein et al.   PEDIATRICS

Asymptomatic transmission and the resurgence of Bordetella pertussis

(2015) Benjamin M. Althouse et al.   BMC Medicine

Antibody Responses After Primary Immunization in Infants Born to Women Receiving a Pertussis-containing Vaccine During Pregnancy: Single Arm Observational Study With a Historical Comparator

(2015) Shamez N. Ladhani et al.   CLINICAL INFECTIOUS DISEASES

Confocal Imaging–Guided Laser Ablation of Basal Cell Carcinomas: An Ex Vivo Study

(2015) Heidy Sierra et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Complement evasion by Bordetella pertussis: implications for improving current vaccines

(2015) Ilse Jongerius et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Structural and functional studies of BapC protein of Bordetella pertussis

(2015) Muhammad Rizwan Riaz et al.   MICROBIOLOGICAL RESEARCH

Pertactin negative Bordetella pertussis demonstrates higher fitness under vaccine selection pressure in a mixed infection model

(2015) Azadeh Safarchi et al.   VACCINE

Whole-genome sequencing reveals the effect of vaccination on the evolution of Bordetella pertussis

(2015) Yinghua Xu et al.   Scientific Reports

Bordetella pertussisevolution in the (functional) genomics era

(2015) Thomas Belcher et al.   Pathogens and Disease

Seroprevalence studies of pertussis: what have we learned from different immunized populations

(2015) Alex-Mikael Barkoff et al.   Pathogens and Disease

TheBordetella pertussis Bps polysaccharide enhances lung colonization by conferring protection from complement-mediated killing

(2014) Tridib Ganguly et al.   CELLULAR MICROBIOLOGY

Pertactin-Negative Bordetella pertussis Strains: Evidence for a Possible Selective Advantage

(2014) S. W. Martin et al.   CLINICAL INFECTIOUS DISEASES

Importance of (antibody-dependent) complement-mediated serum killing in protection againstBordetella pertussis

(2014) Jeroen Geurtsen et al.   Expert Review of Vaccines

Adenylate cyclase toxin-hemolysin relevance for pertussis vaccines

(2014) Peter Sebo et al.   Expert Review of Vaccines

TheBordetellaAdenylate Cyclase Repeat-in-Toxin (RTX) Domain Is Immunodominant and Elicits Neutralizing Antibodies

(2014) Xianzhe Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Proteomics-Identified Bvg-Activated Autotransporters Protect against Bordetella pertussis in a Mouse Model

(2014) Daan de Gouw et al.   PLoS One

Pertactin deficient Bordetella pertussis present a better fitness in mice immunized with an acellular pertussis vaccine

(2014) N. Hegerle et al.   VACCINE

Global Population Structure and Evolution of Bordetella pertussis and Their Relationship with Vaccination

(2014) M. J. Bart et al.   mBio

Reduced Risk of Pertussis Among Persons Ever Vaccinated With Whole Cell Pertussis Vaccine Compared to Recipients of Acellular Pertussis Vaccines in a Large US Cohort

(2013) Maxwell A. Witt et al.   CLINICAL INFECTIOUS DISEASES

Development of a large scale human complement source for use in bacterial immunoassays

(2013) Charlotte Brookes et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Acellular pertussis vaccines protect against disease but fail to prevent infection and transmission in a nonhuman primate model

(2013) J. M. Warfel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Experience with monocomponent acellular pertussis combination vaccines for infants, children, adolescents and adults—A review of safety, immunogenicity, efficacy and effectiveness studies and 15 years of field experience

(2013) Birgit Thierry-Carstensen et al.   VACCINE

Relative Contribution of Th1 and Th17 Cells in Adaptive Immunity to Bordetella pertussis: Towards the Rational Design of an Improved Acellular Pertussis Vaccine

(2013) Pádraig J. Ross et al.   PLoS Pathogens

Immunity to the respiratory pathogen Bordetella pertussis

(2012) R Higgs et al.   Mucosal Immunology

Epigenetic Modifications

(2011) Diane E. Handy et al.   CIRCULATION

BapC autotransporter protein is a virulence determinant of Bordetella pertussis

(2011) Mojtaba Noofeli et al.   MICROBIAL PATHOGENESIS

Bordetella pertussis Autotransporter Vag8 Binds Human C1 Esterase Inhibitor and Confers Serum Resistance

(2011) Nico Marr et al.   PLoS One

Oligosaccharide conjugates of Bordetella pertussis and bronchiseptica induce bactericidal antibodies, an addition to pertussis vaccine

(2011) J. Kubler-Kielb et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A comprehensive analysis of Bordetella pertussis surface proteome and identification of new immunogenic proteins

(2011) Burcu E. Tefon et al.   VACCINE

Interactions between Bordetella pertussis and the complement inhibitor factor H

(2010) Hanne Amdahl et al.   MOLECULAR IMMUNOLOGY

Gene-expression-based quality scores indicate optimal harvest point inBordetella pertussiscultivation for vaccine production

(2009) Bas van de Waterbeemd et al.   BIOTECHNOLOGY AND BIOENGINEERING

Protective activity of the Bordetella pertussis BrkA autotransporter in the murine lung colonization model

(2008) Nico Marr et al.   VACCINE