标题
Aging and Neurodegenerative Disease: Is the Adaptive Immune System a Friend or Foe?
作者
关键词
-
出版物
Frontiers in Aging Neuroscience
Volume 12, Issue -, Pages -
出版商
Frontiers Media SA
发表日期
2020-09-23
DOI
10.3389/fnagi.2020.572090
参考文献
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注意：仅列出部分参考文献，下载原文获取全部文献信息。- Parkinson's disease, aging and adult neurogenesis: Wnt/β‐catenin signalling as the key to unlock the mystery of endogenous brain repair
- (2020) Bianca Marchetti et al. AGING CELL
- Clonally expanded CD8 T cells patrol the cerebrospinal fluid in Alzheimer’s disease
- (2020) David Gate et al. NATURE
- Depletion of CD4 T cells provides therapeutic benefits in aged mice after ischemic stroke
- (2020) Nia M. Harris et al. EXPERIMENTAL NEUROLOGY
- α-Synuclein-specific T cell reactivity is associated with preclinical and early Parkinson’s disease
- (2020) Cecilia S. Lindestam Arlehamn et al. Nature Communications
- Peripheral proinflammatory Th1/Th17 immune cell shift is linked to disease severity in amyotrophic lateral sclerosis
- (2020) Mengmeng Jin et al. Scientific Reports
- Traumatic Spinal Cord Injury: An Overview of Pathophysiology, Models and Acute Injury Mechanisms
- (2019) Arsalan Alizadeh et al. Frontiers in Neurology
- Cytotoxic CD8+T lymphocytes expressing ALS-causing SOD1 mutant selectively trigger death of spinal motoneurons
- (2019) Emmanuelle Coque et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Glial activation and inflammation along the Alzheimer’s disease continuum
- (2019) Kaja Nordengen et al. Journal of Neuroinflammation
- Low-Dose Maraviroc, an Antiretroviral Drug, Attenuates the Infiltration of T Cells into the Central Nervous System and Protects the Nigrostriatum in Hemiparkinsonian Monkeys
- (2019) Susanta Mondal et al. JOURNAL OF IMMUNOLOGY
- Th17 Lymphocytes Induce Neuronal Cell Death in a Human iPSC-Based Model of Parkinson’s Disease
- (2019) Annika Sommer et al. Cell Stem Cell
- Single-cell analysis reveals T cell infiltration in old neurogenic niches
- (2019) Ben W. Dulken et al. NATURE
- The Characterization of Regulatory T-Cell Profiles in Alzheimer’s Disease and Multiple Sclerosis
- (2019) Fausta Ciccocioppo et al. Scientific Reports
- Autoimmunity After Ischemic Stroke and Brain Injury
- (2019) Ehsan Javidi et al. Frontiers in Immunology
- Alzheimer Disease Pathogenesis: Insights From Molecular and Cellular Biology Studies of Oligomeric Aβ and Tau Species
- (2019) Xu-Qiao Chen et al. Frontiers in Neuroscience
- Metformin Restores CNS Remyelination Capacity by Rejuvenating Aged Stem Cells
- (2019) Björn Neumann et al. Cell Stem Cell
- B cells in autoimmune and neurodegenerative central nervous system diseases
- (2019) Joseph J. Sabatino et al. NATURE REVIEWS NEUROSCIENCE
- Ischaemic stroke
- (2019) Bruce C. V. Campbell et al. Nature Reviews Disease Primers
- Aging alters the immunological response to ischemic stroke
- (2018) Rodney M. Ritzel et al. ACTA NEUROPATHOLOGICA
- Single-Cell Chromatin Modification Profiling Reveals Increased Epigenetic Variations with Aging
- (2018) Peggie Cheung et al. CELL
- Disease-Associated Microglia: A Universal Immune Sensor of Neurodegeneration
- (2018) Aleksandra Deczkowska et al. CELL
- Senescent B cells in aging and age-related diseases: Their role in the regulation of antibody responses
- (2018) Daniela Frasca EXPERIMENTAL GERONTOLOGY
- Inflammation in CNS neurodegenerative diseases
- (2018) Jodie Stephenson et al. IMMUNOLOGY
- Evaluation of regulatory T lymphocytes and IL2Ra and FOXP3 gene expression in peripheral mononuclear cells from patients with amyotrophic lateral sclerosis
- (2018) Sara Rashid Chehreh Bargh et al. IRISH JOURNAL OF MEDICAL SCIENCE
- Measurements of auto-antibodies to α-synuclein in the serum and cerebral spinal fluids of patients with Parkinson's disease
- (2018) Rizwan S. Akhtar et al. JOURNAL OF NEUROCHEMISTRY
- Tolerogenic bone marrow-derived dendritic cells induce neuroprotective regulatory T cells in a model of Parkinson’s disease
- (2018) Charles R. Schutt et al. Molecular Neurodegeneration
- Extravascular CD3+ T Cells in Brains of Alzheimer Disease Patients Correlate with Tau but Not with Amyloid Pathology: An Immunohistochemical Study
- (2018) Mario Merlini et al. Neurodegenerative Diseases
- A disconnect between precursor frequency, expansion potential, and site-specific CD4+ T cell responses in aged mice
- (2018) Neha R. Deshpande et al. PLoS One
- Defective cholesterol clearance limits remyelination in the aged central nervous system
- (2018) Ludovico Cantuti-Castelvetri et al. SCIENCE
- Brain Ischemia Induces Diversified Neuroantigen-Specific T-Cell Responses That Exacerbate Brain Injury
- (2018) Wei-Na Jin et al. STROKE
- Multiple Sclerosis Pathology
- (2018) Hans Lassmann Cold Spring Harbor Perspectives in Medicine
- Unbiased transcriptomic analyses reveal distinct effects of immune deficiency in CNS function with and without injury
- (2018) Dandan Luo et al. Protein & Cell
- Association of Regulatory T-Cell Expansion With Progression of Amyotrophic Lateral Sclerosis
- (2018) Rebecca K. Sheean et al. JAMA Neurology
- Reconsideration of Amyloid Hypothesis and Tau Hypothesis in Alzheimer's Disease
- (2018) Fuyuki Kametani et al. Frontiers in Neuroscience
- Imbalance of Circulating Th17 and Regulatory T Cells in Alzheimer’s Disease: A Case Control Study
- (2018) Timo Jan Oberstein et al. Frontiers in Immunology
- STROKE34 Study Protocol: A Randomized Controlled Phase IIa Trial of Intra-Arterial CD34+ Cells in Acute Ischemic Stroke
- (2018) João Sargento-Freitas et al. Frontiers in Neurology
- Counteracting roles of MHCI and CD8+ T cells in the peripheral and central nervous system of ALS SOD1G93A mice
- (2018) Giovanni Nardo et al. Molecular Neurodegeneration
- Functional aspects of meningeal lymphatics in ageing and Alzheimer’s disease
- (2018) Sandro Da Mesquita et al. NATURE
- Peripheral immune system in aging and Alzheimer’s disease
- (2018) Wei Cao et al. Molecular Neurodegeneration
- Brain regulatory T cells suppress astrogliosis and potentiate neurological recovery
- (2018) Minako Ito et al. NATURE
- Microglia in Neurological Diseases: A Road Map to Brain-Disease Dependent-Inflammatory Response
- (2018) Sara Bachiller et al. Frontiers in Cellular Neuroscience
- Tissue-resident memory T cells populate the human brain
- (2018) Joost Smolders et al. Nature Communications
- Human peripheral late/exhausted memory B cells express a senescent-associated secretory phenotype and preferentially utilize metabolic signaling pathways
- (2017) Daniela Frasca et al. EXPERIMENTAL GERONTOLOGY
- The chromatin accessibility signature of human immune aging stems from CD8+T cells
- (2017) Duygu Ucar et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Natural IgM antibodies that bind neoepitopes exposed as a result of spinal cord injury , drive secondary injury by activating complement
- (2017) Aarti Narang et al. Journal of Neuroinflammation
- Safety and efficacy of natalizumab in patients with acute ischaemic stroke (ACTION): a randomised, placebo-controlled, double-blind phase 2 trial
- (2017) Jacob Elkins et al. LANCET NEUROLOGY
- T cells from patients with Parkinson’s disease recognize α-synuclein peptides
- (2017) David Sulzer et al. NATURE
- Regulatory T cells promote myelin regeneration in the central nervous system
- (2017) Yvonne Dombrowski et al. NATURE NEUROSCIENCE
- Regenerating CNS myelin — from mechanisms to experimental medicines
- (2017) Robin J. M. Franklin et al. NATURE REVIEWS NEUROSCIENCE
- Ocrelizumab versus Interferon Beta-1a in Relapsing Multiple Sclerosis
- (2017) Stephen L. Hauser et al. NEW ENGLAND JOURNAL OF MEDICINE
- Pathology of Neurodegenerative Diseases
- (2017) Brittany N. Dugger et al. Cold Spring Harbor Perspectives in Biology
- Signs and symptoms preceding the diagnosis of Alzheimer’s disease: a systematic scoping review of literature from 1937 to 2016
- (2017) Fidelia Bature et al. BMJ Open
- Elevated Serum α-Synuclein Autoantibodies in Patients with Parkinson’s Disease Relative to Alzheimer’s Disease and Controls
- (2017) Ali Shalash et al. Frontiers in Neurology
- Amyotrophic lateral sclerosis
- (2017) Orla Hardiman et al. Nature Reviews Disease Primers
- Impaired toll like receptor-7 and 9 induced immune activation in chronic spinal cord injured patients contributes to immune dysfunction
- (2017) Gozde Gucluler et al. PLoS One
- Hippocampal T cell infiltration promotes neuroinflammation and cognitive decline in a mouse model of tauopathy
- (2016) Cyril Laurent et al. BRAIN
- Regulatory T cells delay disease progression in Alzheimer-like pathology
- (2016) Cira Dansokho et al. BRAIN
- Pathogenesis of amyotrophic lateral sclerosis
- (2016) Sarah Morgan et al. BRITISH MEDICAL BULLETIN
- Aging of the immune system: Focus on inflammation and vaccination
- (2016) Marcello Pinti et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Treatment of traumatic brain injury with anti-inflammatory drugs
- (2016) Peter J. Bergold EXPERIMENTAL NEUROLOGY
- Epigenetic changes in T-cell and monocyte signatures and production of neurotoxic cytokines in ALS patients
- (2016) Larry Lam et al. FASEB JOURNAL
- Ageing and recurrent episodes of neuroinflammation promote progressive experimental autoimmune encephalomyelitis in Biozzi ABH mice
- (2016) Laura A. N. Peferoen et al. IMMUNOLOGY
- Age-Associated Resident Memory CD8 T Cells in the Central Nervous System Are Primed To Potentiate Inflammation after Ischemic Brain Injury
- (2016) Rodney M. Ritzel et al. JOURNAL OF IMMUNOLOGY
- Inhibition of the JAK/STAT Pathway Protects Against α-Synuclein-Induced Neuroinflammation and Dopaminergic Neurodegeneration
- (2016) Hongwei Qin et al. JOURNAL OF NEUROSCIENCE
- Down-regulation of B cell-related genes in peripheral blood leukocytes of Parkinson's disease patients with and without GBA mutations
- (2016) Hila Kobo et al. MOLECULAR GENETICS AND METABOLISM
- Ageing, neurodegeneration and brain rejuvenation
- (2016) Tony Wyss-Coray NATURE
- Human memory T cells with a naive phenotype accumulate with aging and respond to persistent viruses
- (2016) Vesna Pulko et al. NATURE IMMUNOLOGY
- PD-1 immune checkpoint blockade reduces pathology and improves memory in mouse models of Alzheimer's disease
- (2016) Kuti Baruch et al. NATURE MEDICINE
- Age at onset and Parkinson disease phenotype
- (2016) Gennaro Pagano et al. NEUROLOGY
- B-Cell Depletion with CD20 Antibodies as New Approach in the Treatment of Inflammatory and Immunological Events Associated with Spinal Cord Injury
- (2016) Giovanna Casili et al. Neurotherapeutics
- The adaptive immune system restrains Alzheimer’s disease pathogenesis by modulating microglial function
- (2016) Samuel E. Marsh et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Inflammatory neuroprotection following traumatic brain injury
- (2016) M. V. Russo et al. SCIENCE
- Understanding the Role of T Cells in CNS Homeostasis
- (2016) Erik Ellwardt et al. TRENDS IN IMMUNOLOGY
- Friend or foe: the dichotomous impact of T cells on neuro-de/re-generation during aging
- (2016) Brandon Coder et al. Oncotarget
- Do human B-lymphocytes avoid aging until 60 years?
- (2016) Andrea Knight et al. Oncotarget
- Neuroprotective effects of CD4+CD25+Foxp3+ regulatory T cells in a 3xTg-AD Alzheimer’s disease model
- (2016) Hyunjung Baek et al. Oncotarget
- Brain-derived neurotrophic factor protects against tau-related neurodegeneration of Alzheimer’s disease
- (2016) S-S Jiao et al. Translational Psychiatry
- Aging affects B-cell antigen receptor repertoire diversity in primary and secondary lymphoid tissues
- (2015) Hilla Tabibian-Keissar et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Development of stage-dependent glycans on the Fc domains of IgG antibodies of ALS animals
- (2015) Meital Edri-Brami et al. EXPERIMENTAL NEUROLOGY
- MHCII-independent CD4+ T cells protect injured CNS neurons via IL-4
- (2015) James T. Walsh et al. JOURNAL OF CLINICAL INVESTIGATION
- Thymic Involution Perturbs Negative Selection Leading to Autoreactive T Cells That Induce Chronic Inflammation
- (2015) Brandon D. Coder et al. JOURNAL OF IMMUNOLOGY
- Age-related changes in spleen of Dark Agouti rats immunized for experimental autoimmune encephalomyelitis
- (2015) Jasmina Djikić et al. JOURNAL OF NEUROIMMUNOLOGY
- Experimental autoimmune encephalomyelitis and age-related correlations of NADPH oxidase, MMP-9, and cell adhesion molecules: The increased disease severity and blood–brain barrier permeability in middle-aged mice
- (2015) Ji-Eun Seo et al. JOURNAL OF NEUROIMMUNOLOGY
- Transfer of Myelin-Reactive Th17 Cells Impairs Endogenous Remyelination in the Central Nervous System of Cuprizone-Fed Mice
- (2015) E. G. Baxi et al. JOURNAL OF NEUROSCIENCE
- B-Lymphocyte-Mediated Delayed Cognitive Impairment following Stroke
- (2015) K. P. Doyle et al. JOURNAL OF NEUROSCIENCE
- Clinical correlation of peripheral CD4+-cell sub-sets, their imbalance and Parkinson's disease
- (2015) YUHUA CHEN et al. Molecular Medicine Reports
- β2-microglobulin is a systemic pro-aging factor that impairs cognitive function and neurogenesis
- (2015) Lucas K Smith et al. NATURE MEDICINE
- Breaking immune tolerance by targeting Foxp3+ regulatory T cells mitigates Alzheimer’s disease pathology
- (2015) Kuti Baruch et al. Nature Communications
- Aging diminishes the resistance of AO rats to EAE: putative role of enhanced generation of GM-CSF Expressing CD4+ T cells in aged rats
- (2015) Zorica Stojić-Vukanić et al. Immunity & Ageing
- Aging impairs peritoneal but not bone marrow-derived macrophage phagocytosis
- (2014) Eimear Linehan et al. AGING CELL
- Modest familial risks for multiple sclerosis: a registry-based study of the population of Sweden
- (2014) Helga Westerlind et al. BRAIN
- High TNF-α levels in resting B cells negatively correlate with their response
- (2014) Daniela Frasca et al. EXPERIMENTAL GERONTOLOGY
- The paradox of chronic neuroinflammation, systemic immune suppression, autoimmunity after traumatic chronic spinal cord injury
- (2014) Jan M. Schwab et al. EXPERIMENTAL NEUROLOGY
- T cell–derived interleukin (IL)-21 promotes brain injury following stroke in mice
- (2014) Benjamin D.S. Clarkson et al. JOURNAL OF EXPERIMENTAL MEDICINE
- FTY720 does not protect from traumatic brain injury in mice despite reducing posttraumatic inflammation
- (2014) Stine Mencl et al. JOURNAL OF NEUROIMMUNOLOGY
- Antigen Dependently Activated Cluster of Differentiation 8-Positive T Cells Cause Perforin-Mediated Neurotoxicity in Experimental Stroke
- (2014) E. Mracsko et al. JOURNAL OF NEUROSCIENCE
- Evidence for peripheral immune activation in amyotrophic lateral sclerosis
- (2014) Xueping Chen et al. JOURNAL OF THE NEUROLOGICAL SCIENCES
- The prevalence of Parkinson's disease: A systematic review and meta-analysis
- (2014) Tamara Pringsheim et al. MOVEMENT DISORDERS
- Risk of relapse phenotype recurrence in multiple sclerosis
- (2014) Tomas Kalincik et al. Multiple Sclerosis Journal
- Comparing clinical features of young onset, middle onset and late onset Parkinson's disease
- (2014) Raja Mehanna et al. PARKINSONISM & RELATED DISORDERS
- Aging-induced type I interferon response at the choroid plexus negatively affects brain function
- (2014) K. Baruch et al. SCIENCE
- Interleukin-17 inhibits Adult Hippocampal Neurogenesis
- (2014) Qiang Liu et al. Scientific Reports
- Traumatic brain injury causes selective, CD74-dependent peripheral lymphocyte activation that exacerbates neurodegeneration
- (2014) Richard P Tobin et al. Acta Neuropathologica Communications
- Characteristics of differentiated CD8+ and CD4+ T cells present in the human brain
- (2013) Joost Smolders et al. ACTA NEUROPATHOLOGICA
- Aging aggravates ischemic stroke-induced brain damage in mice with chronic peripheral infection
- (2013) Hiramani Dhungana et al. AGING CELL
- In senescence, age-associated B cells secrete TNFα and inhibit survival of B-cell precursors*
- (2013) Michelle Ratliff et al. AGING CELL
- Inflammation and white matter degeneration persist for years after a single traumatic brain injury
- (2013) Victoria E. Johnson et al. BRAIN
- Brain antigen-reactive CD4+ T cells are sufficient to support learning behavior in mice with limited T cell repertoire
- (2013) Ali Radjavi et al. BRAIN BEHAVIOR AND IMMUNITY
- T helper-17 activation dominates the immunologic milieu of both amyotrophic lateral sclerosis and progressive multiple sclerosis
- (2013) Marina Saresella et al. CLINICAL IMMUNOLOGY
- Differential effects of aging and sex on stroke induced inflammation across the lifespan
- (2013) Bharti Manwani et al. EXPERIMENTAL NEUROLOGY
- Impaired inhibitory function of circulating CD4+CD25+ regulatory T cells in alopecia areata
- (2013) Bong Seok Shin et al. JOURNAL OF DERMATOLOGICAL SCIENCE
- Dopamine Receptor D3 Expressed on CD4+ T Cells Favors Neurodegeneration of Dopaminergic Neurons during Parkinson's Disease
- (2013) H. Gonzalez et al. JOURNAL OF IMMUNOLOGY
- Cutting Edge: Central Memory CD8 T Cells in Aged Mice Are Virtual Memory Cells
- (2013) B.-C. Chiu et al. JOURNAL OF IMMUNOLOGY
- IFN- Production by Amyloid -Specific Th1 Cells Promotes Microglial Activation and Increases Plaque Burden in a Mouse Model of Alzheimer's Disease
- (2013) T. C. Browne et al. JOURNAL OF IMMUNOLOGY
- GM-CSF induces neuroprotective and anti-inflammatory responses in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine intoxicated mice
- (2013) Lisa M. Kosloski et al. JOURNAL OF NEUROIMMUNOLOGY
- Autonomic Dysreflexia Causes Chronic Immune Suppression after Spinal Cord Injury
- (2013) Y. Zhang et al. JOURNAL OF NEUROSCIENCE
- The influence of age and gender on motor and non-motor features of early Parkinson's disease: Initial findings from the Oxford Parkinson Disease Center (OPDC) discovery cohort
- (2013) Konrad Szewczyk-Krolikowski et al. PARKINSONISM & RELATED DISORDERS
- Th17 Cell-Mediated Neuroinflammation Is Involved in Neurodegeneration of Aβ1-42-Induced Alzheimer’s Disease Model Rats
- (2013) Jun Zhang et al. PLoS One
- CNS-specific immunity at the choroid plexus shifts toward destructive Th2 inflammation in brain aging
- (2013) K. Baruch et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Inflammation and Adaptive Immunity in Parkinson's Disease
- (2013) R. L. Mosley et al. Cold Spring Harbor Perspectives in Medicine
- The Genetics of Alzheimer Disease
- (2013) R. E. Tanzi Cold Spring Harbor Perspectives in Medicine
- A single administration of human umbilical cord blood T cells produces long-lasting effects in the aging hippocampus
- (2012) Md Shahaduzzaman et al. AGE
- Evidence of Intrathecal Immunoglobulin Synthesis in Stroke
- (2012) Harald Prüss et al. ARCHIVES OF NEUROLOGY
- Brain-Immune Interactions and Ischemic Stroke
- (2012) Costantino Iadecola ARCHIVES OF NEUROLOGY
- Neutralization of the IL-17 axis diminishes neutrophil invasion and protects from ischemic stroke
- (2012) M. Gelderblom et al. BLOOD
- Regulatory T-lymphocytes mediate amyotrophic lateral sclerosis progression and survival
- (2012) Jenny S. Henkel et al. EMBO Molecular Medicine
- Improved regeneration after spinal cord injury in mice lacking functional T- and B-lymphocytes
- (2012) Bin Wu et al. EXPERIMENTAL NEUROLOGY
- CD4+ Regulatory and Effector/Memory T Cell Subsets Profile Motor Dysfunction in Parkinson’s Disease
- (2012) Jessica A. Hutter Saunders et al. Journal of Neuroimmune Pharmacology
- Reduced T helper and B lymphocytes in Parkinson's disease
- (2012) Claire H. Stevens et al. JOURNAL OF NEUROIMMUNOLOGY
- Tumor necrosis factor-α synthesis inhibitor 3,6′-dithiothalidomide attenuates markers of inflammation, Alzheimer pathology and behavioral deficits in animal models of neuroinflammation and Alzheimer’s disease
- (2012) David Tweedie et al. Journal of Neuroinflammation
- Challenging the Role of Adaptive Immunity in Neurotrauma: Rag1−/− Mice Lacking Mature B and T Cells Do Not Show Neuroprotection after Closed Head Injury
- (2012) Sebastian Weckbach et al. JOURNAL OF NEUROTRAUMA
- Multiple Sclerosis Risk Variant HLA-DRB1*1501 Associates with High Expression of DRB1 Gene in Different Human Populations
- (2012) Antonio Alcina et al. PLoS One
- Glycans in Sera of Amyotrophic Lateral Sclerosis Patients and Their Role in Killing Neuronal Cells
- (2012) Meital Edri-Brami et al. PLoS One
- Adoptive transfer of Th1-conditioned lymphocytes promotes axonal remodeling and functional recovery after spinal cord injury
- (2012) H Ishii et al. Cell Death & Disease
- A B-cell subset uniquely responsive to innate stimuli accumulates in aged mice
- (2011) Y. Hao et al. BLOOD
- Inhibition of lymphocyte trafficking shields the brain against deleterious neuroinflammation after stroke
- (2011) Arthur Liesz et al. BRAIN
- Endogenous regulatory T lymphocytes ameliorate amyotrophic lateral sclerosis in mice and correlate with disease progression in patients with amyotrophic lateral sclerosis
- (2011) David R. Beers et al. BRAIN
- Functional recovery in aging mice after experimental stroke
- (2011) Bharti Manwani et al. BRAIN BEHAVIOR AND IMMUNITY
- Non-Resolving Aspects of Acute Inflammation after Spinal Cord Injury (SCI): Indices and Resolution Plateau
- (2011) Harald Prüss et al. BRAIN PATHOLOGY
- Experimental autoimmune encephalomyelitis (EAE) as a model for multiple sclerosis (MS)
- (2011) Cris S Constantinescu et al. BRITISH JOURNAL OF PHARMACOLOGY
- FTD and ALS: A Tale of Two Diseases
- (2011) R. Ferrari et al. Current Alzheimer Research
- A comprehensive assessment of the SOD1G93A low-copy transgenic mouse, which models human amyotrophic lateral sclerosis
- (2011) A. Acevedo-Arozena et al. Disease Models & Mechanisms
- Increased apoptosis, curtailed expansion and incomplete differentiation of CD8+ T cells combine to decrease clearance of L. monocytogenes in old mice
- (2011) Megan J. Smithey et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Effects of aging on blood brain barrier and matrix metalloproteases following controlled cortical impact in mice
- (2011) Phil Lee et al. EXPERIMENTAL NEUROLOGY
- Effects of peripheral lymphocyte subpopulations and the clinical correlation with Parkinson's disease
- (2011) Fumitoshi Niwa et al. Geriatrics & Gerontology International
- An Alzheimer's disease-relevant presenilin-1 mutation augments amyloid-beta-induced oligodendrocyte dysfunction
- (2011) Maya K. Desai et al. GLIA
- The syndrome of cognitive impairment in amyotrophic lateral sclerosis: a population-based study
- (2011) Julie Phukan et al. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
- Neurite outgrowth is differentially impacted by distinct immune cell subsets
- (2011) Madeline Pool et al. MOLECULAR AND CELLULAR NEUROSCIENCE
- Age at onset as a determinant of presenting phenotype and initial relapse recovery in multiple sclerosis
- (2011) M Cossburn et al. Multiple Sclerosis Journal
- The ageing systemic milieu negatively regulates neurogenesis and cognitive function
- (2011) Saul A. Villeda et al. NATURE
- Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis
- (2011) Stephen Sawcer et al. NATURE
- The age-related deficit in LTP is associated with changes in perfusion and blood-brain barrier permeability
- (2011) Christoph W. Blau et al. NEUROBIOLOGY OF AGING
- Nonrandom attrition of the naive CD8+ T-cell pool with aging governed by T-cell receptor:pMHC interactions
- (2011) B. D. Rudd et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Autoimmune Responses to the Brain After Stroke Are Associated With Worse Outcome
- (2011) Kyra J. Becker et al. STROKE
- Mouse Model of Middle Cerebral Artery Occlusion
- (2011) Terrance Chiang et al. Jove-Journal of Visualized Experiments
- Parkinson's disease and immunological abnormalities: increase of HLA-DR expression on monocytes in cerebrospinal fluid and of CD45RO+ T cells in peripheral blood
- (2010) U. Fiszer et al. ACTA NEUROLOGICA SCANDINAVICA
- Early detrimental T-cell effects in experimental cerebral ischemia are neither related to adaptive immunity nor thrombus formation
- (2010) C. Kleinschnitz et al. BLOOD
- Relationships between age and late progression of Parkinson's disease: a clinico-pathological study
- (2010) P. A. Kempster et al. BRAIN
- Activation of mixed glia by Aβ-specific Th1 and Th17 cells and its regulation by Th2 cells
- (2010) K. McQuillan et al. BRAIN BEHAVIOR AND IMMUNITY
- Myelin antigen reactive T cells in cerebrovascular diseases
- (2010) W. Z. WANG et al. CLINICAL AND EXPERIMENTAL IMMUNOLOGY
- Inflammation in neurodegenerative diseases
- (2010) Sandra Amor et al. IMMUNOLOGY
- Overview of the immune response
- (2010) David D. Chaplin JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Regulation of learning and memory by meningeal immunity: a key role for IL-4
- (2010) Noël C. Derecki et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Regulatory T Cells Attenuate Th17 Cell-Mediated Nigrostriatal Dopaminergic Neurodegeneration in a Model of Parkinson’s Disease
- (2010) Ashley D. Reynolds et al. JOURNAL OF IMMUNOLOGY
- A Placebo-Controlled Trial of Oral Cladribine for Relapsing Multiple Sclerosis
- (2010) Gavin Giovannoni et al. NEW ENGLAND JOURNAL OF MEDICINE
- A Placebo-Controlled Trial of Oral Fingolimod in Relapsing Multiple Sclerosis
- (2010) Ludwig Kappos et al. NEW ENGLAND JOURNAL OF MEDICINE
- Functional and Pathogenic Differences of Th1 and Th17 Cells in Experimental Autoimmune Encephalomyelitis
- (2010) Helena S. Domingues et al. PLoS One
- Regulation of cytokine signaling and T-cell recruitment in the aging mouse brain in response to central inflammatory challenge
- (2009) Yuan-Zhong Xu et al. BRAIN BEHAVIOR AND IMMUNITY
- Brain dendritic cells in ischemic stroke: Time course, activation state, and origin
- (2009) Jennifer C. Felger et al. BRAIN BEHAVIOR AND IMMUNITY
- Incidence and lifetime risk of motor neuron disease in the United Kingdom: a population-based study
- (2009) A. Alonso et al. EUROPEAN JOURNAL OF NEUROLOGY
- Adaptive peripheral immune response increases proliferation of neural precursor cells in the adult hippocampus
- (2009) Susanne A. Wolf et al. FASEB JOURNAL
- B cells produce pathogenic antibodies and impair recovery after spinal cord injury in mice
- (2009) Daniel P. Ankeny et al. JOURNAL OF CLINICAL INVESTIGATION
- Th1, Th17, and Th9 Effector Cells Induce Experimental Autoimmune Encephalomyelitis with Different Pathological Phenotypes
- (2009) A. Jager et al. JOURNAL OF IMMUNOLOGY
- Nitrated -Synuclein-Induced Alterations in Microglial Immunity Are Regulated by CD4+ T Cell Subsets
- (2009) A. D. Reynolds et al. JOURNAL OF IMMUNOLOGY
- CD4-Positive T Lymphocytes Provide a Neuroimmunological Link in the Control of Adult Hippocampal Neurogenesis
- (2009) S. A. Wolf et al. JOURNAL OF IMMUNOLOGY
- Development of ALS-like disease in SOD-1 mice deficient of B lymphocytes
- (2009) Shulamit Naor et al. JOURNAL OF NEUROLOGY
- Chronic Traumatic Encephalopathy in Athletes: Progressive Tauopathy After Repetitive Head Injury
- (2009) Ann C. McKee et al. JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY
- Reproductive age-related changes in the blood brain barrier: Expression of IgG and tight junction proteins
- (2009) Shameena Bake et al. MICROVASCULAR RESEARCH
- Pivotal role of cerebral interleukin-17–producing γδT cells in the delayed phase of ischemic brain injury
- (2009) Takashi Shichita et al. NATURE MEDICINE
- Regulatory T cells are key cerebroprotective immunomodulators in acute experimental stroke
- (2009) Arthur Liesz et al. NATURE MEDICINE
- Aβ-specific Th2 cells provide cognitive and pathological benefits to Alzheimer's mice without infiltrating the CNS
- (2009) Chuanhai Cao et al. NEUROBIOLOGY OF DISEASE
- B-cell diversity decreases in old age and is correlated with poor health status
- (2008) Kate L. Gibson et al. AGING CELL
- Amyloid Plaque and Neurofibrillary Tangle Pathology in a Regulatable Mouse Model of Alzheimer's Disease
- (2008) Jennifer B. Paulson et al. AMERICAN JOURNAL OF PATHOLOGY
- Adaptive immunity affects learning behavior in mice
- (2008) Anna Brynskikh et al. BRAIN BEHAVIOR AND IMMUNITY
- Infiltration of CD4+ lymphocytes into the brain contributes to neurodegeneration in a mouse model of Parkinson disease
- (2008) Vanessa Brochard et al. JOURNAL OF CLINICAL INVESTIGATION
- Alemtuzumab vs. Interferon Beta-1a in Early Multiple Sclerosis
- (2008) NEW ENGLAND JOURNAL OF MEDICINE
- Nitrated α–Synuclein Immunity Accelerates Degeneration of Nigral Dopaminergic Neurons
- (2008) Eric J. Benner et al. PLoS One
- Adaptive Immune Neuroprotection in G93A-SOD1 Amyotrophic Lateral Sclerosis Mice
- (2008) Rebecca Banerjee et al. PLoS One
- CD4+ T cells support glial neuroprotection, slow disease progression, and modify glial morphology in an animal model of inherited ALS
- (2008) D. R. Beers et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- T lymphocytes potentiate endogenous neuroprotective inflammation in a mouse model of ALS
- (2008) I. M. Chiu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Stroke Outcome in Those Over 80
- (2008) Gustavo Saposnik et al. STROKE
- Genetic epidemiology: the use of old and new tools for multiple sclerosis
- (2008) Sreeram V. Ramagopalan et al. TRENDS IN NEUROSCIENCES
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