Analysis of brain region-specific co-expression networks reveals clustering of established and novel genes associated with Alzheimer disease

Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing

(2019) Brian W. Kunkle et al.   NATURE GENETICS

Regional Heterogeneity in Gene Expression, Regulation, and Coherence in the Frontal Cortex and Hippocampus across Development and Schizophrenia

(2019) Leonardo Collado-Torres et al.   NEURON

Genetic architecture of subcortical brain structures in 38,851 individuals

(2019) Claudia L. Satizabal et al.   NATURE GENETICS

The cholinergic system in the pathophysiology and treatment of Alzheimer’s disease

(2018) Harald Hampel et al.   BRAIN

A molecular network of the aging human brain provides insights into the pathology and cognitive decline of Alzheimer’s disease

(2018) Sara Mostafavi et al.   NATURE NEUROSCIENCE

Genome-wide pleiotropy analysis of neuropathological traits related to Alzheimer’s disease

(2018) Jaeyoon Chung et al.   Alzheimers Research & Therapy

One for all and all for One: Improving replication of genetic studies through network diffusion

(2018) Daniel Lancour et al.   PLoS Genetics

Resting-state connectivity in neurodegenerative disorders: Is there potential for an imaging biomarker?

(2018) Christian Hohenfeld et al.   NeuroImage-Clinical

Heat Shock Proteins in Alzheimer’s Disease: Role and Targeting

(2018) Claudia Campanella et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Loss of HDAC5 Impairs Memory Function: Implications for Alzheimer's Disease

(2018) Roberto Carlos Agis-Balboa et al.   JOURNAL OF ALZHEIMERS DISEASE

Inhibition of HDAC3 reverses Alzheimer’s disease-related pathologies in vitro and in the 3xTg-AD mouse model

(2018) Karolina J. Janczura et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Network propagation: a universal amplifier of genetic associations

(2017) Lenore Cowen et al.   NATURE REVIEWS GENETICS

Conditional deletion of Eps8 reduces hippocampal synaptic plasticity and impairs cognitive function

(2017) Yu-Ting Wang et al.   NEUROPHARMACOLOGY

The development prospection of HDAC inhibitors as a potential therapeutic direction in Alzheimer’s disease

(2017) Shuang-shuang Yang et al.   Translational Neurodegeneration

Epidemiology of Parkinson's disease

(2016) A. Elbaz et al.   REVUE NEUROLOGIQUE

Integrative network analysis of nineteen brain regions identifies molecular signatures and networks underlying selective regional vulnerability to Alzheimer’s disease

(2016) Minghui Wang et al.   Genome Medicine

RCAN1 overexpression promotes age-dependent mitochondrial dysregulation related to neurodegeneration in Alzheimer’s disease

(2015) Helen Wong et al.   ACTA NEUROPATHOLOGICA

The Genotype-Tissue Expression (GTEx) Project

(2015) Latarsha J. Carithers et al.   BIOPRESERVATION AND BIOBANKING

The Genotype-Tissue Expression (GTEx) Project

(2015) Latarsha J. Carithers et al.   Biopreservation and Biobanking

Sharing and Specificity of Co-expression Networks across 35 Human Tissues

(2015) Emma Pierson et al.   PLoS Computational Biology

Aberrant Expression of RCAN1 in Alzheimer’s Pathogenesis: A New Molecular Mechanism and a Novel Drug Target

(2014) Yili Wu et al.   MOLECULAR NEUROBIOLOGY

Exome Sequencing Links Corticospinal Motor Neuron Disease to Common Neurodegenerative Disorders

(2014) G. Novarino et al.   SCIENCE

Integrated Systems Approach Identifies Genetic Nodes and Networks in Late-Onset Alzheimer’s Disease

(2013) Bin Zhang et al.   CELL

Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease

(2013) Jean-Charles Lambert et al.   NATURE GENETICS

An integrative approach to ortholog prediction for disease-focused and other functional studies

(2011) Yanhui Hu et al.   BMC BIOINFORMATICS

Stages of the Pathologic Process in Alzheimer Disease: Age Categories From 1 to 100 Years

(2011) Heiko Braak et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Adult hippocampal neurogenesis and its role in Alzheimer's disease

(2011) Yangling Mu et al.   Molecular Neurodegeneration

The pathological process underlying Alzheimer’s disease in individuals under thirty

(2010) Heiko Braak et al.   ACTA NEUROPATHOLOGICA

Bioinformatics challenges for genome-wide association studies

(2010) J. H. Moore et al.   BIOINFORMATICS

METAL: fast and efficient meta-analysis of genomewide association scans

(2010) C. J. Willer et al.   BIOINFORMATICS

Inhibitors of Catalase-Amyloid Interactions Protect Cells from β-Amyloid-Induced Oxidative Stress and Toxicity

(2010) Lila K. Habib et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Whole genome association study of brain-wide imaging phenotypes for identifying quantitative trait loci in MCI and AD: A study of the ADNI cohort

(2010) Li Shen et al.   NEUROIMAGE

Associating Genes and Protein Complexes with Disease via Network Propagation

(2010) Oron Vanunu et al.   PLoS Computational Biology

Common Inherited Variation in Mitochondrial Genes Is Not Enriched for Associations with Type 2 Diabetes or Related Glycemic Traits

(2010) Ayellet V. Segrè et al.   PLoS Genetics

Inhibitors of Class 1 Histone Deacetylases Reverse Contextual Memory Deficits in a Mouse Model of Alzheimer's Disease

(2009) Mark Kilgore et al.   NEUROPSYCHOPHARMACOLOGY

Regional homogeneity in depression and its relationship with separate depressive symptom clusters: A resting-state fMRI study

(2008) Zhijian Yao et al.   JOURNAL OF AFFECTIVE DISORDERS