RCAN1 overexpression promotes age-dependent mitochondrial dysregulation related to neurodegeneration in Alzheimer’s disease
出版年份 2015 全文链接
标题
RCAN1 overexpression promotes age-dependent mitochondrial dysregulation related to neurodegeneration in Alzheimer’s disease
作者
关键词
RCAN1, DRP1, Mitochondria, Fission, Calcineurin, Aging
出版物
ACTA NEUROPATHOLOGICA
Volume 130, Issue 6, Pages 829-843
出版商
Springer Nature
发表日期
2015-10-25
DOI
10.1007/s00401-015-1499-8
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- RCAN1 Regulates Mitochondrial Function and Increases Susceptibility to Oxidative Stress in Mammalian Cells
- (2014) Heshan Peiris et al. Oxidative Medicine and Cellular Longevity
- Regulator of Calcineurin 1 Modulates Expression of Innate Anxiety and Anxiogenic Responses to Selective Serotonin Reuptake Inhibitor Treatment
- (2013) Charles A. Hoeffer et al. JOURNAL OF NEUROSCIENCE
- Overexpression of RCAN1 isoform 4 in mouse neurons leads to a moderate behavioral impairment
- (2013) Devang L Bhoiwala et al. NEUROLOGICAL RESEARCH
- Alzheimer disease in the United States (2010-2050) estimated using the 2010 census
- (2013) L. E. Hebert et al. NEUROLOGY
- Unraveling the complexity of neurodegeneration in brains of subjects with Down syndrome: Insights from proteomics
- (2013) Marzia Perluigi et al. Proteomics Clinical Applications
- Tau pathology induces loss of GABAergic interneurons leading to altered synaptic plasticity and behavioral impairments
- (2013) Josien Levenga et al. Acta Neuropathologica Communications
- Regulation of RCAN1 translation and its role in oxidative stress-induced apoptosis
- (2012) Yili Wu et al. FASEB JOURNAL
- Over-expression of RCAN1 causes Down syndrome-like hippocampal deficits that alter learning and memory
- (2012) Katherine R. Martin et al. HUMAN MOLECULAR GENETICS
- Abnormal interaction between the mitochondrial fission protein Drp1 and hyperphosphorylated tau in Alzheimer's disease neurons: implications for mitochondrial dysfunction and neuronal damage
- (2012) M. Manczak et al. HUMAN MOLECULAR GENETICS
- Chronic Expression of RCAN1-1L Protein Induces Mitochondrial Autophagy and Metabolic Shift from Oxidative Phosphorylation to Glycolysis in Neuronal Cells
- (2012) Gennady Ermak et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Correlation of Alzheimer Disease Neuropathologic Changes With Cognitive Status: A Review of the Literature
- (2012) Peter T. Nelson et al. JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY
- Creation and characterization of BAC-transgenic mice with physiological overexpression of epitope-tagged RCAN1 (DSCR1)
- (2012) Luzhou Xing et al. MAMMALIAN GENOME
- Mitochondrial Dysfunction—A Pharmacological Target in Alzheimer's Disease
- (2012) Gunter P. Eckert et al. MOLECULAR NEUROBIOLOGY
- Abnormal mitochondrial dynamics and synaptic degeneration as early events in Alzheimer's disease: Implications to mitochondria-targeted antioxidant therapeutics
- (2011) P. Hemachandra Reddy et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Mild Cognitive Impairment (MCI) - The Novel Trend of Targeting Alzheimers Disease in Its Early Stages - Methodological Considerations
- (2011) C. Pater Current Alzheimer Research
- Do RCAN1 proteins link chronic stress with neurodegeneration?
- (2011) Gennady Ermak et al. FASEB JOURNAL
- Impaired mitochondrial dynamics and abnormal interaction of amyloid beta with mitochondrial protein Drp1 in neurons from patients with Alzheimer's disease: implications for neuronal damage
- (2011) Maria Manczak et al. HUMAN MOLECULAR GENETICS
- Regulator of Calcineurin 1 (RCAN1) Facilitates Neuronal Apoptosis through Caspase-3 Activation
- (2011) Xiulian Sun et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Amyloid -Induced Impairments in Hippocampal Synaptic Plasticity Are Rescued by Decreasing Mitochondrial Superoxide
- (2011) T. Ma et al. JOURNAL OF NEUROSCIENCE
- Delayed ischemic postconditioning protects hippocampal CA1 neurons by preserving mitochondrial integrity via Akt/GSK3β signaling
- (2011) Caifeng Zhou et al. NEUROCHEMISTRY INTERNATIONAL
- Behavioral Characterization of a Mouse Model Overexpressing DSCR1/ RCAN1
- (2011) Mara Dierssen et al. PLoS One
- Animal and human studies with the mitochondria-targeted antioxidant MitoQ
- (2010) Robin A.J. Smith et al. Annals of the New York Academy of Sciences
- Neural mechanisms of ageing and cognitive decline
- (2010) Nicholas A. Bishop et al. NATURE
- Can Alzheimer disease be prevented by amyloid-β immunotherapy?
- (2010) Cynthia A. Lemere et al. Nature Reviews Neurology
- The role of abnormal mitochondrial dynamics in the pathogenesis of Alzheimer’s disease
- (2009) Xinglong Wang et al. JOURNAL OF NEUROCHEMISTRY
- Role of Calcineurin Signaling in Membrane Potential-Regulated Maturation of Cerebellar Granule Cells
- (2009) M. Okazawa et al. JOURNAL OF NEUROSCIENCE
- Impaired Balance of Mitochondrial Fission and Fusion in Alzheimer's Disease
- (2009) X. Wang et al. JOURNAL OF NEUROSCIENCE
- Interaction between TAK1–TAB1–TAB2 and RCAN1–calcineurin defines a signalling nodal control point
- (2009) Qinghang Liu et al. NATURE CELL BIOLOGY
- The RCAN carboxyl end mediates calcineurin docking-dependent inhibition via a site that dictates binding to substrates and regulators
- (2009) S. Martinez-Martinez et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Removal of FKBP12 Enhances mTOR-Raptor Interactions, LTP, Memory, and Perseverative/Repetitive Behavior
- (2008) Charles A. Hoeffer et al. NEURON
- Dephosphorylation by calcineurin regulates translocation of Drp1 to mitochondria
- (2008) G. M. Cereghetti et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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