Correction
Multidisciplinary Sciences
Ying X. Gue, Maria Tennyson, Jovia Gao, Shuhui Ren, Rahim Kanji, Diana A. Gorog
Summary: A revised version of this paper has been published and can be accessed through the link at the top of the paper.
SCIENTIFIC REPORTS
(2021)
Article
Medicine, General & Internal
Hsin-Pei Chung, Yen-Hsiang Tang, Chun-Yen Chen, Chao-Hsien Chen, Wen-Kuei Chang, Kuan-Chih Kuo, Yen-Ting Chen, Jou-Chun Wu, Chang-Yi Lin, Chieh-Jen Wang
Summary: The aim of this study was to externally validate the predictive capability of five developed COVID-19-specific prognostic tools. The SEIMC score and Shang COVID severity score showed good performance in predicting 30-day mortality, while the COVID-IRS-NLR and VICE scores performed well in predicting invasive mechanical ventilation.
FRONTIERS IN MEDICINE
(2023)
Article
Medicine, General & Internal
Yu-Feng Xiao, Jia-Lin He, Yu Xu, Xi Liu, Hui Lin, Qi Li, Zhi Xu, Ming-Dong Hu, Xiao-Bao Ren, Cheng Zhang, Wen-Jing Zhang, Wei Duan, Yong-Feng Tian, Ping Li, Hao Wu, Cai-Ping Song, En Liu, Shi-Ming Yang
Summary: Diabetes is a risk factor for poor prognosis in COVID-19 patients. The severity of disease and mortality in diabetic COVID-19 patients is closely associated with factors like dyspnea, cardiovascular diseases, neutrophil count, PLT count, and CKMB levels. A risk score model based on these factors can predict the severity of disease in diabetic COVID-19 patients.
FRONTIERS IN MEDICINE
(2021)
Article
Health Care Sciences & Services
Stavroula Zanelli, Agamemnon Bakakos, Zoi Sotiropoulou, Andriana I. Papaioannou, Evangelia Koukaki, Efstathia Potamianou, Anna Kyriakoudi, Evangelos Kaniaris, Petros Bakakos, Evangelos J. Giamarellos-Bourboulis, Antonia Koutsoukou, Nikoletta Rovina
Summary: This study assessed the modified Severe COvid Prediction Estimate score (mSCOPE) as a predictor of mortality in ICU-admitted severe COVID-19 pneumonia patients. The results showed that patients with higher mSCOPE scores had a higher mortality rate and were correlated with disease severity, comorbidity severity, days on mechanical ventilation, and days of ICU stay. The mSCOPE score can be a useful tool for risk stratification in patients with severe COVID-19.
JOURNAL OF PERSONALIZED MEDICINE
(2023)
Article
Multidisciplinary Sciences
Chen-Yang Su, Sirui Zhou, Edgar Gonzalez-Kozlova, Guillaume Butler-Laporte, Elsa Brunet-Ratnasingham, Tomoko Nakanishi, Wonseok R. Jeon, David Morrison, Laetitia Laurent, Jonathan Afilalo, Marc Afilalo, Danielle Henry, Yiheng Chen, Julia Carrasco-Zanini, Yossi Farjoun, Maik Pietzner, Nofar Kimchi, Zaman Afrasiabi, Nardin Rezk, Meriem Bouab, Louis Petitjean, Charlotte Guzman, Xiaoqing Xue, Chris Tselios, Branka Vulesevic, Olumide Adeleye, Tala Abdullah, Noor Almamlouk, Yara Moussa, Chantal DeLuca, Naomi Duggan, Erwin Schurr, Nathalie Brassard, Madeleine Durand, Diane Marie Del Valle, Ryan A. Thompson, Mario Cedillo, Eric Schadt, Kai W. Nie, Nicole Simons, Konstantinos Mouskas, Nicolas Zaki, Manishkumar Patel, Hui Xie, Jocelyn Harris, Robert Marvin, Esther Cheng, Kevin Tuballes, Kimberly Argueta, Ieisha Scott, Celia M. T. Greenwood, Clare A. Paterson, Michael Hinterberg, Claudia Langenberg, Vincenzo Forgetta, Joelle Pineau, Vincent Mooser, Thomas D. Marron, Noam Beckmann, Seunghee W. Kim-schulze, Alexander Charney, Sacha E. Gnjatic, Daniel Kaufmann, Miriam Merad, J. Brent Richards
Summary: Measuring the abundance of 4701 proteins in the blood can help predict COVID-19 severity and guide clinical treatment.
SCIENTIFIC REPORTS
(2023)
Article
Pharmacology & Pharmacy
C. Karacaer, S. Yaylaci, K. Issever, H. Sert, K. O. Suner, E. Cokluk, A. Nalbant, T. Demirci, C. Varim, T. Kaya
Summary: The study aimed to investigate the role of neopterin levels in predicting the need for intensive care and mortality in COVID-19 patients. The results showed that there was no significant association between neopterin and COVID-19 mortality in this study, highlighting the need for more comprehensive, prospective, randomized controlled studies with larger sample sizes.
EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES
(2022)
Article
Infectious Diseases
Mohamed El-Kassas, Maha El Gaafary, Mohamed Elbadry, Mohamed Ahmed Medhat, Hany Dabbous, Essam Ali Hassan, Ahmed Abdelmoaty, Haidi Karam-Allah, Hamdy Sayed, Amr Abdalazeem, Ahmed Fouad Sherief, Eman Fares, Maha Alsadik, Ehab Moustafa, Wagida Anwar, Hossam Abdelghaffar, Khaled Abdelghaffar
Summary: This study evaluated the clinical and laboratory features of hospitalized COVID-19 patients and developed a scoring system that accurately predicts the severity and mortality of COVID-19.
JOURNAL OF INFECTION IN DEVELOPING COUNTRIES
(2022)
Article
Endocrinology & Metabolism
Aisha R. Saand, Monica Flores, Tariq Kewan, Sura Alqaisi, Mahmoud Alwakeel, Lori Griffiths, Xiaofeng Wang, Xiaozhen Han, Robert Burton, Mohammed J. Al-Jaghbeer, Francois Abi Fadel
Summary: The study shows that hyperglycemia in COVID-19 patients is significantly associated with prolonged ICU stay, higher need of mechanical ventilation, and increased risk of mortality. Old age and hyperglycemia are the main predictors of in-hospital mortality.
JOURNAL OF DIABETES
(2021)
Article
Biochemistry & Molecular Biology
Laure Abensur Vuillaume, Francois Lefebvre, Axel Benhamed, Amandine Schnee, Mathieu Hoffmann, Fernanda Godoy Falcao, Nathan Haber, Jonathan Sabah, Charles-Eric Lavoignet, Pierrick Le Borgne
Summary: This study investigates the prognostic value of the LCR ratio as a marker for severity and mortality in COVID-19 infection. A retrospective cohort study was conducted on 1035 COVID-19 patients in six major hospitals in northeast France. The results suggest that the LCR could serve as a predictive marker for severe forms of COVID-19 at the initial stage in the Emergency Department.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Biochemistry & Molecular Biology
Mickael Gette, Sara Fernandes, Marion Marlinge, Marine Duranjou, Wijayanto Adi, Maelle Dambo, Pierre Simeone, Pierre Michelet, Nicolas Bruder, Regis Guieu, Julien Fromonot
Summary: The study developed a PREDICT score to predict the need for intensive care of COVID-19 patients already hospitalized in standard medical units. The score includes clinical and biological parameters and can accurately identify most patients who require intensive care, particularly for those at significant risk after at least one day of hospitalization.
Review
Public, Environmental & Occupational Health
Chepkoech Buttia, Erand Llanaj, Hamidreza Raeisi-Dehkordi, Lum Kastrati, Mojgan Amiri, Renald Mecani, Petek Eylul Taneri, Sergio Alejandro Gomez Ochoa, Peter Francis Raguindin, Faina Wehrli, Farnaz Khatami, Octavio Pano Espinola, Lyda Z. Rojas, Aurelie Pahud de Mortanges, Eric Francis Macharia-Nimietz, Fadi Alijla, Beatrice Minder, Alexander B. Leichtle, Nora Luethi, Simone Ehrhard, Yok-Ai Que, Laurenz Kopp Fernandes, Wolf Hautz, Taulant Muka
Summary: Current evidence on COVID-19 prognostic models is inconsistent and controversial. A systematic review of 314 eligible articles from over 40 countries was performed, which identified and assessed 353 prognostic models predicting adverse outcomes in COVID-19 patients. These models were found to have limitations in generalizability and methodological concerns. Future well-designed prospective studies are needed to address remaining uncertainties.
EUROPEAN JOURNAL OF EPIDEMIOLOGY
(2023)
Article
Biochemistry & Molecular Biology
Wilfredo F. Garcia-Beltran, Evan C. Lam, Michael G. Astudillo, Diane Yang, Tyler E. Miller, Jared Feldman, Blake M. Hauser, Timothy M. Caradonna, Kiera L. Clayton, Adam D. Nitido, Mandakolathur R. Murali, Galit Alter, Richelle C. Charles, Anand Dighe, John A. Branda, Jochen K. Lennerz, Daniel Lingwood, Aaron G. Schmidt, A. John Iafrate, Alejandro B. Balazs
Summary: Severe cases of COVID-19 show increased inflammatory markers, lymphopenia, pro-inflammatory cytokines, and high antibody levels. High neutralization potency is a predictor of survival. Patient sera can neutralize different strains, indicating cross-protection from reinfection.
Article
Multidisciplinary Sciences
Shunsuke Amagasa, Masahiro Kashiura, Hideto Yasuda, Mineji Hayakawa, Kazuma Yamakawa, Akira Endo, Takayuki Ogura, Atsushi Hirayama, Hideo Yasunaga, Takashi Tagami
Summary: This study aimed to evaluate the association between ICU patient volume prior to COVID-19 pandemic and outcomes of ventilated COVID-19 patients. The results showed that institutional intensive care patient volume was not significantly associated with in-hospital death in ventilated COVID-19 patients.
SCIENTIFIC REPORTS
(2022)
Article
Medicine, General & Internal
Athina Nasoufidou, Marianthi Kavelidou, Theodora Griva, Eleni Melikidou, Charalampos Maskalidis, Konstantina Machaira, Barbara Nikolaidou
Summary: This study aimed to assess the possible correlation between length of hospitalization (LOS) and clinical laboratory data of COVID-19 patients upon admission, including the total severity score (TSS) from chest computed tomography (CT). The results showed that LOS was associated with age and TSS, and the early identification of disease severity using TSS and patients' age could be useful for allocating inpatient resources and maintaining vigilance for those requiring long-term hospitalizations.
FRONTIERS IN MEDICINE
(2023)
Article
Emergency Medicine
Daniel Martin Simadibrata, Julius Calvin, Alya Darin Wijaya, Naufal Arkan Abiyyu Ibrahim
Summary: High neutrophil-to-lymphocyte ratio (NLR) levels upon admission were associated with severe COVID-19 and mortality. Further studies are needed to determine the optimal cut-off value for NLR before clinical use.
AMERICAN JOURNAL OF EMERGENCY MEDICINE
(2021)
Article
Clinical Neurology
Rafael De la Garza Ramos, Jong Hyun Choi, Ishan Naidu, Joshua A. Benton, Murray Echt, Vijay Yanamadala, Peter G. Passias, John H. Shin, David J. Altschul, C. Rory Goodwin, Daniel M. Sciubba, Reza Yassari
Summary: This retrospective cohort study aimed to investigate the impact of race on complications following spinal tumor surgery. The results showed that Black patients who underwent metastatic spinal tumor surgery were at a significantly higher risk of minor complications compared to non-Hispanic Whites. However, there was no significant difference in major complications between the two racial groups.
GLOBAL SPINE JOURNAL
(2023)
Article
Clinical Neurology
Adisson Fortunel, Kainaat Javed, Ryan Holland, Samuel Ahmad, Neil Haranhalli, David Altschul
Summary: This study aims to identify risk factors associated with incomplete occlusion of aneurysms treated with the Woven EndoBridge device at short-term follow up. Larger aneurysm diameter was found to be an independent risk factor for incomplete occlusion.
INTERVENTIONAL NEURORADIOLOGY
(2023)
Article
Clinical Neurology
Juan Vivanco-Suarez, Alan Mendez-Ruiz, Mudassir Farooqui, Kimon Bekelis, Justin A. Singer, Kainaat Javed, David J. Altschul, Johanna T. Fifi, Stavros Matsoukas, Jared Cooper, Fawaz Al-Mufti, Bradley Gross, Brian Jankowitz, Peter T. Kan, Muhammad Hafeez, Emanuele Orru, Andres Dajles, Milagros Galecio-Castillo, Cynthia B. Zevallos, Ajay K. Wakhloo, Santiago Ortega-Gutierrez
Summary: This retrospective multicenter study examined the safety and efficacy of the Surpass Streamline flow diverter in a large United States cohort of patients with intracranial aneurysms. The results demonstrated that the Surpass Streamline had a favorable safety and efficacy profile for treating both large and wide-necked small and medium-sized intracranial aneurysms.
INTERVENTIONAL NEURORADIOLOGY
(2023)
Editorial Material
Clinical Neurology
David J. Altschul
INTERVENTIONAL NEURORADIOLOGY
(2023)
Article
Clinical Neurology
Kainaat Javed, Adisson Fortunel, Ryan Holland, Deepak Khatri, Samuel Ahmad, Neil Haranhalli, David Altschul
Summary: This study retrospectively analyzed 42 patients treated with WEB and found that patients with underlying arrhythmias, a larger angle in the true neck view, and a longer procedure length were more likely to experience thromboembolic complications. However, these risk factors did not reach statistical significance in logistic regression modeling.
INTERVENTIONAL NEURORADIOLOGY
(2023)
Article
Clinical Neurology
Edwin McCray, Romaric Waguia, Rafael de la Garza Ramos, Meghan J. Price, Theresa Williamson, Tara Dalton, Daniel M. Sciubba, Reza Yassari, Andrea N. Goodwin, Peter Fecci, Margaret O. Johnson, Kaisorn Chaichana, C. Rory Goodwin
Summary: This study assessed the impact of race on short-term patient outcomes in the brain metastasis population. It found that minority patients experienced disparities in treatment, in-hospital complications, and mortality rates compared to White patients.
NEURO-ONCOLOGY PRACTICE
(2023)
Article
Orthopedics
Rafael De la Garza Ramos, Kainaat Javed, Jessica Ryvlin, Yaroslav Gelfand, Saikiran Murthy, Reza Yassari
Summary: This study investigated whether social factors are associated with postoperative ambulation and overall survival in patients undergoing metastatic spinal tumor surgery. The results showed no association between race, Social Vulnerability Index (SVI) score, insurance status, and postoperative ambulation or overall survival.
CLINICAL ORTHOPAEDICS AND RELATED RESEARCH
(2023)
Review
Clinical Neurology
Murray Echt, Rafael De la Garza Ramos, Eric Geng, Ula Isleem, Julia Schwarz, Steven Girdler, Andrew Platt, Adewale A. Bakare, Richard G. Fessler, Samuel K. Cho
Summary: Surgical decompression alone for patients with neurogenic leg pain in the setting of degenerative lumbar scoliosis (DLS) and stenosis is commonly performed. However, there is limited evidence summarizing the outcomes. Current literature suggests that selective patients with DLS who undergo decompression alone had minimal progression of Cobb angle, relatively low reoperation rate, and favorable patient-reported outcomes.
GLOBAL SPINE JOURNAL
(2023)
Article
Clinical Neurology
Rafael De La Garza Ramos, Jessica Ryvlin, Mousa K. K. Hamad, Benjamin Wang, Yaroslav Gelfand, Saikiran Murthy, Reza Yassari
Summary: The utility of low muscle mass (LMM) in predicting 90-day and 12-month mortality after spinal tumor surgery was assessed in this study. The results showed that patients with LMM had higher rates of 90-day and 12-month mortality, but this was not independent of other factors such as performance status, hypoalbuminemia, or primary cancer type.
EUROPEAN SPINE JOURNAL
(2023)
Article
Clinical Neurology
J. C. Ku, A. A. Dmytriw, M. A. Essibayi, M. A. Banihashemi, J. E. Vranic, S. Ghozy, D. Altschul, R. W. Regenhardt, C. J. Stapleton, V. X. D. Yang, A. B. Patel
Summary: Middle meningeal artery embolization is a safe and effective treatment for chronic subdural hematomas, with lower rates of recurrence and complications compared to traditional surgical methods.
AMERICAN JOURNAL OF NEURORADIOLOGY
(2023)
Review
Clinical Neurology
Kainaat Javed, Sertac Kirnaz, Richard Zampolin, Deepak Khatri, Rose Fluss, Adisson Fortunel, Ryan Holland, Mousa K. Hamad, Julio Fidel Ko Inocencio, Ariel Stock, Aleka Scoco, Rafael De La Garza Ramos, Samuel Ahmad, Neil Haranhalli, David Altschul
Summary: This article presents the experience of treating craniocervical junction dural arteriovenous fistulas (DAVF) and a systematic review of the literature. The authors found that the venous drainage pattern of CCJ DAVF can be classified into inferior, superior, and mixed types, and treatment choices depend on the drainage pattern. They also developed a classification system to describe the drainage pattern, treatment choices, and outcomes.
JOURNAL OF CLINICAL NEUROSCIENCE
(2023)
Article
Clinical Neurology
Mitchell S. Fourman, Layla Siraj, Julia Duvall, Duncan C. Ramsey, Rafael De La Garza Ramos, Muhamed Hadzipasic, Ian Connolly, Theresa Williamson, Ganesh M. Shankar, Andrew Schoenfeld, Reza Yassari, Elie Massaad, John H. Shin
Summary: This study aimed to group patients with metastatic breast cancer to the spine who required open surgery based on functional level and disease characteristics, in order to identify factors that lead to poor outcomes. A retrospective analysis of patients managed at two tertiary referral centers from 2008 to 2020 was conducted. Five patient clusters were identified based on function at presentation, preoperative spine radiation, structural instability, epidural spinal cord compression (ESCC), neural deficits, and tumor location/hormone status. The results can assist in managing expectations and identifying at-risk patients following surgical intervention.
WORLD NEUROSURGERY
(2023)
Article
Clinical Neurology
Rafael de la Garza Ramos, Jessica Ryvlin, Mousa K. Hamad, Mitchell S. Fourman, Ananth Eleswarapu, Yaroslav Gelfand, Saikiran G. Murthy, John H. Shin, Reza Yassari
Summary: The prognostic nutritional index (PNI) is independently associated with 90-day and 12-month mortality after spinal metastasis surgery, regardless of factors such as tumor size and primary tumor site.
EUROPEAN SPINE JOURNAL
(2023)
Letter
Clinical Neurology
Muhammed Amir Essibayi, David J. Altschul