Article
Biotechnology & Applied Microbiology
Xianlin He, Bo Liu, Yali Xu, Ze Chen, Hao Li
Summary: The presence of Lactobacillus plantarum can increase the ethanol tolerance of Saccharomyces cerevisiae by promoting or inhibiting various metabolic processes in the yeast cells, and the maintenance of this tolerance depends on the coexistence of both organisms. The study also suggested a complex relationship between yeast and contaminating LAB, which may play a beneficial role in fermentation by promoting the ethanol tolerance of yeast.
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
(2021)
Article
Multidisciplinary Sciences
Neelja Singhal, Nambram Somendro Singh, Shilpa Mohanty, Manish Kumar, Jugsharan Singh Virdi
Summary: The study reported the isolation and evaluation of probiotic capabilities of Lactiplantibacillus plantarum strains from rhizospheric soil, which showed strong hypocholesterolemic potential and resistance to various environmental stresses, as well as exhibited resistance to acidic environment and multiple antibiotics. Further investigation is recommended for its potential as a potent probiotic with hypocholesterolemic biotherapeutic benefits, and the potential of exploring rhizosphere as a niche for isolating microorganisms with probiotic potential.
SCIENTIFIC REPORTS
(2021)
Article
Agriculture, Multidisciplinary
Xue Luo, Mo Li, Henan Zhang, Danli Yan, Shuaiqi Ji, Rina Wu, Yongfu Chen
Summary: Proteomics and bioinformatics analysis of three strains of Lactobacillus plantarum under salt stress revealed differential expression of proteins related to protein biosynthesis, nucleotide metabolism, and sugar metabolism. Specific differentially expressed proteins were found between the strains in response to high salt conditions.
JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE
(2021)
Article
Biochemistry & Molecular Biology
Rong Xu, Tong Wang, Fei-Fei Ding, Nan-Nan Zhou, Fang Qiao, Li-Qiao Chen, Zhen-Yu Du, Mei-Ling Zhang
Summary: In this study, it was found that Lactobacillus plantarum MR1, a probiotic strain, can modulate gut microbiota, increase intestinal acetate content, and subsequently increase circulating uridine levels, thereby ameliorating high-carbohydrate diet-induced hepatic lipid accumulation and oxidative stress. This suggests that gut microbiota can regulate nucleotide metabolism to maintain host physiological homeostasis.
Article
Biochemistry & Molecular Biology
Yanhua Cui, Meihong Wang, Yankun Zheng, Kai Miao, Xiaojun Qu
Summary: Lactiplantibacillus plantarum possesses a strong ability in carbohydrate utilization, with a rich set of carbohydrate metabolism genes and a higher number of two-component systems (TCSs) compared to other lactic acid bacteria, showing strain specificity. Analysis of regulatory and sugar metabolism gene expressions suggests that certain TCSs may play a role in regulating sugar metabolism.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Biochemistry & Molecular Biology
Jong-Yeon Kim, Eun-Jung Park, Hae-Jeung Lee
Summary: L. plantarum HAC01 lysate can inhibit adipogenesis and regulate the expression of genes involved in lipid metabolism. It can also affect the phosphorylation levels of important energy metabolism regulators. These findings suggest that L. plantarum HAC01 lysate may be a useful agent for the treatment of obesity.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Nutrition & Dietetics
Zhiwei Yan, Zhuangzhuang Liu, Yong Ma, Zhao Yang, Gang Liu, Jun Fang
Summary: This study explores the alleviating effects of L. plantarum H-6 on antibiotic-associated diarrhea, revealing that it can regulate colonic microbial composition, improve serum metabolic process, and reduce the symptoms of antibiotic-associated diarrhea.
Article
Nutrition & Dietetics
Jin-Peng Hu, Ting-Ting Zheng, Bin-Fen Zeng, Man-Ling Wu, Rui Shi, Ye Zhang, Li-Jiao Chen, Wen-Jian Cheng, Peng Liang
Summary: The supplementation of LPLJ fermented with Lactobacillus plantarum FZU3013 was found to have positive effects on modulating lipid metabolism, reducing hyperlipidaemia, and adjusting biochemical indicators in rats fed a high-fat diet. Overall, this study suggests that LPLJ may be a functional food that can help prevent hyperlipidaemia by impacting various metabolic pathways.
FRONTIERS IN NUTRITION
(2021)
Article
Food Science & Technology
Guangqiang Wang, Huaning Yu, Xin Feng, Hongyu Tang, Zhiqiang Xiong, Yongjun Xia, Lianzhong Ai, Xin Song
Summary: This study explored the importance of different bsh genes in the bile salt resistance of L. plantarum AR113, revealing that bsh 1 and bsh 3 genes are critical for BSH activity and preferentially degrade glycine-conjugated bile salts. The results suggest that bsh 1 and bsh 3 are closely related to bile salt resistance, providing valuable insights for selecting strains with high tolerance to bile salts in a rational, high-throughput manner.
LWT-FOOD SCIENCE AND TECHNOLOGY
(2021)
Article
Biochemistry & Molecular Biology
Jingheng Liang, Yan Zhou, Guihua Tang, Ruixue Wu, Huancai Lin
Summary: This study found that the cell-free supernatant of Lactobacillus plantarum has a strong antibiofilm effect on Streptococcus mutans, and the main antibiofilm substance is a mixture of lactic acid and valine.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Chemistry, Applied
Guoyan Liu, Meng Chu, Piao Xu, Shiying Nie, Xin Xu, Jiaoyan Ren
Summary: The study found that Ilisha elongata protein is beneficial for the proliferation and adhesion of probiotics in the intestines, and can be used as an active protein beneficial to intestinal health.
Article
Agriculture, Multidisciplinary
Li Zeng, Zerong Liu, Luxin Zhou, Meng Chen, Xuewei Zheng, Pengfei Yang, Xinrui Zhao, Zhongmin Tian
Summary: The study found that protein-rich almond supplementation can prevent salt-induced hypertension by regulating amino acid metabolism, increasing nitric oxide content, and alleviating oxidative stress.
JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE
(2022)
Article
Food Science & Technology
Mengwei Wang, Yang Li, Jie Yang, Rui Shi, Liu Xiong, Qingjie Sun
Summary: This study investigated the adsorption amounts and antibacterial effects of inorganic nanoparticles on probiotic bacteria. Results showed that food-grade NPs have bactericidal effects on L. plantarum and L. fermentum.
LWT-FOOD SCIENCE AND TECHNOLOGY
(2021)
Article
Nutrition & Dietetics
Dongting Yang, Wentao Lyu, Ziyi Hu, Jiting Gao, Zhiyao Zheng, Weijun Wang, Jenni Firrman, Daxi Ren
Summary: The study evaluated the probiotic effects of Lactobacillus fermentum ZJUIDS06 and Lactobacillus plantarum ZY08 on hyperlipidemic golden hamsters, demonstrating that Lactobacillus fermentum ZJUIDS06 increased colon SCFA levels, reduced serum LDL, total cholesterol, and triglycerides, and altered the cecum microbiota. Particularly, Lactobacillus fermentum ZJUIDS06 increased the abundance of Parabacteroides, indicating its potential in lowering cholesterol levels.
FRONTIERS IN NUTRITION
(2021)
Article
Food Science & Technology
Xin Kang, Zihan Gao, Lingjie Zheng, Xiaoru Zhang, Hao Li
Summary: Co-cultivation of Lactobacillus plantarum with Saccharomyces cerevisiae can reduce intracellular reactive oxygen species levels in yeast cells, increase oxidative tolerance, and promote ATP production.
LWT-FOOD SCIENCE AND TECHNOLOGY
(2021)
Article
Endocrinology & Metabolism
Wanglong Gou, Liang Yue, Xin-yi Tang, Yan-yan Wu, Xue Cai, Menglei Shuai, Zelei Miao, Yuanqing Fu, Hao Chen, Zengliang Jiang, Jiali Wang, Yunyi Tian, Congmei Xiao, Nan Xiang, Zhen Wu, Yu-ming Chen, Tiannan Guo, Ju-Sheng Zheng
Summary: This study identified proteomic biomarkers for incident T2D among Chinese populations and found seven proteins associated with T2D. The research also indicated a potential synergistic interaction between dietary factors such as red meat intake and these biomarkers in exaggerating the risk of T2D.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2022)
Article
Food Science & Technology
Jingjing Shi, Chaoran Xia, Qiyuan Tian, Xiaoqun Zeng, Zhen Wu, Yuxing Guo, Daodong Pan
Summary: In this study, Limosilactobacillus fermentum RC4 was cultured and found to have effective nitrite degradation ability. During the process of nitrite degradation, significant metabolic changes occurred, mainly involving amino acid and purine metabolism. Additionally, energy supply was enhanced, antioxidant capacity was reduced, and cell growth was inhibited.
LWT-FOOD SCIENCE AND TECHNOLOGY
(2022)
Article
Biochemistry & Molecular Biology
Hai Xu, Lifeng Lao, Chunyu Ji, Qianqian Lu, Yuxing Guo, Daodong Pan, Zhen Wu
Summary: In this study, the LPxTG-motif protein derived from L.reuteri was found to enhance the adhesion characteristics and intestinal survival rate of L.reuteri, as well as promote the signaling molecule production in Lactobacillus strains. Additionally, the LPxTG-motif protein exhibited anti-inflammatory activity by inhibiting the expressions of inflammatory cytokines TNF-alpha and IL-1 beta through MAPK signaling cascades. These findings provide insights into the multifunctional role of LPxTG-motif surface protein derived from L.reuteri in the gastrointestinal tract environment.
MOLECULAR IMMUNOLOGY
(2022)
Article
Food Science & Technology
Qiang Xia, Changyu Zhou, Zhen Wu, Daodong Pan, Jinxuan Cao
Summary: Processomics is a method that combines chemical fingerprinting and kinetic modeling for quality evaluation in food processing and preservation. Currently, it mainly focuses on volatile compounds, resulting in biases. This study proposes the integration of other omics technology platforms to provide a comprehensive analysis of variations in chemical fingerprinting, and the establishment of kinetic mechanistic models to indicate quality-related reactions. Additionally, sensomics can be introduced as a special dimension for quality assessment.
CURRENT OPINION IN FOOD SCIENCE
(2022)
Article
Microbiology
Jianzhu Wen, Yixing Yu, Mengqi Chen, Lei Cui, Qiang Xia, Xiaoqun Zeng, Yuxing Guo, Daodong Pan, Zhen Wu
Summary: This study investigated the tolerance, adhesion ability, and biofilm formation of a Lactobacillus strain in a coculture system using various methods. The results showed that the coculture system promoted the release of signal molecules and protected the viability of Lactobacillus acidophilus in the gastrointestinal environment. Additionally, an amino acid-derived metabolite was found to enhance cell communication and increase the tolerance ability of L. acidophilus.
MICROBIOLOGY SPECTRUM
(2022)
Article
Food Science & Technology
Qianqian Lu, Yingqi Guo, Guo Yang, Lei Cui, Zhen Wu, Xiaoqun Zeng, Daodong Pan, Zhendong Cai
Summary: LTA molecules derived from different Lactobacillus strains exhibit heterogeneity and contribute to the distinguishable adhesion properties of Lactobacillus strains. These LTAs can alleviate inflammatory responses and block certain inflammatory pathways, making them potential alternative therapeutics for ulcerative colitis treatment.
Article
Nutrition & Dietetics
Zhendong Cai, Guowei Zhong, Qianqian Liu, Xingqiao Yang, Xiaoxia Zhang, Song Zhou, Xiaoqun Zeng, Zhen Wu, Daodong Pan
Summary: This study constructed a two-tube hexaplex PCR method for accurate molecular authentication of twelve meat species. The method showed specificity, sensitivity, and reproducibility, and was suitable for food inspection. It was successfully applied to detect meat frauds in commercial meat products.
FRONTIERS IN NUTRITION
(2022)
Article
Food Science & Technology
Fengxuan Lang, Jianzhu Wen, Zhen Wu, Daodong Pan, Linjun Wang
Summary: Lactic acid bacteria fermentation is a simple and safe method of food preservation. Using probiotics in yoghurt can improve the flavor, texture, and health benefits of dairy products. This study found that the mixed culture condition enhanced the texture properties of yoghurt, and L. plantarum A3 fermented yoghurt accumulated additional components that led to significant sensory differences. These results suggest that L. plantarum A3 is a potential probiotic strain that enhances the sensory and nutritional properties of fermented milk.
FOOD SCIENCE AND HUMAN WELLNESS
(2022)
Article
Microbiology
Zihang Shi, Xiefei Li, Xiankang Fan, Jue Xu, Qing Liu, Zhen Wu, Daodong Pan
Summary: The number of viable lactic acid bacteria (LAB) is crucial for evaluating the quality of fermented milk. This study used the PMA-qPCR method to rapidly and quantitatively detect the number of viable bacteria of each LAB species in fermented milk. By analyzing the pheS gene, it was found that pheS gene resolved species identities better and was thus selected to design specific primers and probes. The results showed that PMA-qPCR detected significantly lower numbers of viable bacteria compared to qPCR, indicating the effectiveness of PMA in inhibiting amplification of DNA from dead cells.
FRONTIERS IN MICROBIOLOGY
(2022)
Review
Food Science & Technology
Xiankang Fan, Xiefei Li, Lihui Du, Jianhao Li, Jue Xu, Zihang Shi, Chunwei Li, Maoling Tu, Xiaoqun Zeng, Zhen Wu, Daodong Pan
Summary: This paper reviews the effects, mechanisms, and research methods of using natural plant-based homogenates (NPBH) as additives to improve the quality of yogurt. NPBH promotes the growth of lactic acid bacteria, affects the texture and flavor of yogurt, and enhances its nutritional value. Future research could focus on adding Chinese herbs with various health benefits to yogurt, and investigating the clinical implications of NPBH yogurt.
Article
Nutrition & Dietetics
Yan Cheng, Sha Wang, Shilong Ju, Song Zhou, Xiaoqun Zeng, Zhen Wu, Daodong Pan, Guowei Zhong, Zhendong Cai
Summary: A multiplex PCR method has been developed for the molecular authentication of seven different species of meat. The method is highly accurate and reproducible, making it suitable for various meat samples. This technology is of great significance for addressing the issue of meat adulteration.
Article
Nutrition & Dietetics
Jue Xu, Yingyan Chen, Xiankang Fan, Zihang Shi, Mingzhen Liu, Xiaoqun Zeng, Zhen Wu, Daodong Pan
Summary: This study screened LAB with antioxidant capacity, prepared corn fermented milk with antioxidant capacity, and extracted two new peptides with antioxidant capacity. The research provides new ideas and basis for the development of functional dairy products.
FRONTIERS IN NUTRITION
(2022)
Article
Food Science & Technology
Xiaofeng Ji, Tao Deng, Yingping Xiao, Canghong Jin, Wentao Lyu, Zhen Wu, Wen Wang, Xiaoli Wang, Qinfang He, Hua Yang
Summary: Emerging Alternaria and Fusarium mycotoxins in tomatoes and derived tomato products pose potential health risks to humans. This study developed a method for simultaneous quantification of these mycotoxins in tomatoes and their products. The results showed that mycotoxins were detected in various tomato products, with the highest contamination levels found in tomato powders. Children may have higher dietary exposure to these mycotoxins compared to adults. The presence of these mycotoxins in derived tomato products may be a health concern, especially for children and those consuming a high amount of these products.
Article
Agriculture, Multidisciplinary
Weimei Kong, Junai Gan, Mi Su, Binyi Xiong, Xiaoxiao Jiang, Tao Zhang, Xiaoqun Zeng, Zhen Wu, Yangying Sun, Daodong Pan, Qing Liu, Nan Ling, Yuxing Guo
Summary: This study investigated the functional domains of the S-layer protein in Lactobacillus acidophilus CICC 6074, identifying the C-terminal domain as the binding region and the cell wall-anchored receptor as teichoic acid. N-terminal truncations of the protein were found to self-assemble into liposomes and were responsible for cell adhesion.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
(2022)
Article
Food Science & Technology
Lingyu Kong, Yuze Huang, Xiaoqun Zeng, Congyan Ye, Zhen Wu, Yuxing Guo, Daodong Pan
Summary: Galactosyltransferase (GalT) is an important enzyme in EPS synthesis, improving freeze-drying resistance in lactic acid bacteria. The study shows that GalT regulates membrane transport system, sugar metabolism, and quorum sensing to enhance EPS biosynthesis.
FOOD CHEMISTRY: MOLECULAR SCIENCES
(2022)