Role of Inflammation and Immunity in Hypertension: Recent Epidemiological, Laboratory, and Clinical Evidence

Differentiation of human innate lymphoid cells (ILCs)

(2016) Kerstin Juelke et al.   CURRENT OPINION IN IMMUNOLOGY

Deficiency of T-regulatory cells exaggerates angiotensin II-induced microvascular injury by enhancing immune responses

(2016) Muhammad Oneeb Rehman Mian et al.   JOURNAL OF HYPERTENSION

Blood Neutrophil to Lymphocyte Ratio as a Predictor of Hypertension

(2015) Xing Liu et al.   AMERICAN JOURNAL OF HYPERTENSION

Oxidative Stress and Human Hypertension: Vascular Mechanisms, Biomarkers, and Novel Therapies

(2015) Augusto C. Montezano et al.   CANADIAN JOURNAL OF CARDIOLOGY

Renal Denervation Prevents Immune Cell Activation and Renal Inflammation in Angiotensin II–Induced HypertensionNovelty and Significance

(2015) Liang Xiao et al.   CIRCULATION RESEARCH

Inflammation, Immunity, and Hypertensive End-Organ Damage

(2015) W. G. McMaster et al.   CIRCULATION RESEARCH

Myeloid Suppressor Cells Accumulate and Regulate Blood Pressure in HypertensionNovelty and Significance

(2015) Kandarp H. Shah et al.   CIRCULATION RESEARCH

Dose-Dependent Bidirectional Effect of Angiotensin IV on Abdominal Aortic Aneurysm via Variable Angiotensin Receptor StimulationNovelty and Significance

(2015) Jing Kong et al.   HYPERTENSION

Renal Transporter Activation During Angiotensin-II Hypertension is Blunted in Interferon-γ−/−and Interleukin-17A−/−MiceNovelty and Significance

(2015) Nikhil V. Kamat et al.   HYPERTENSION

Obligatory Role for B Cells in the Development of Angiotensin II–Dependent HypertensionNovelty and Significance

(2015) Christopher T. Chan et al.   HYPERTENSION

FcγRIIB and autoimmunity

(2015) Marion Espéli et al.   IMMUNOLOGICAL REVIEWS

Lymphocyte adaptor protein LNK deficiency exacerbates hypertension and end-organ inflammation

(2015) Mohamed A. Saleh et al.   JOURNAL OF CLINICAL INVESTIGATION

Immune activation caused by vascular oxidation promotes fibrosis and hypertension

(2015) Jing Wu et al.   JOURNAL OF CLINICAL INVESTIGATION

The burgeoning family of unconventional T cells

(2015) Dale I Godfrey et al.   NATURE IMMUNOLOGY

Immunity in arterial hypertension: associations or causalities?

(2015) Hans-Joachim Anders et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Plasma Inflammatory Markers and the Risk of Developing Hypertension in Men

(2015) Howard D. Sesso et al.   Journal of the American Heart Association

γδT Cells: First Line of Defense and Beyond

(2014) Yueh-hsiu Chien et al.   Annual Review of Immunology

Treatment with telmisartan/rosuvastatin combination has a beneficial synergistic effect on ameliorating Th17/Treg functional imbalance in hypertensive patients with carotid atherosclerosis

(2014) Zhendong Liu et al.   ATHEROSCLEROSIS

Is atherosclerosis an autoimmune disease?

(2014) Eiji Matsuura et al.   BMC Medicine

B Cells and Humoral Immunity in Atherosclerosis

(2014) Dimitrios Tsiantoulas et al.   CIRCULATION RESEARCH

Innate Immunity in Hypertension

(2014) Muhammad Oneeb Rehman Mian et al.   CURRENT HYPERTENSION REPORTS

Dual opposing roles of adaptive immunity in hypertension

(2014) N. Idris-Khodja et al.   EUROPEAN HEART JOURNAL

Macrophage Activation and Polarization: Nomenclature and Experimental Guidelines

(2014) Peter J. Murray et al.   IMMUNITY

The Angiogenic Factor PlGF Mediates a Neuroimmune Interaction in the Spleen to Allow the Onset of Hypertension

(2014) Daniela Carnevale et al.   IMMUNITY

DC isoketal-modified proteins activate T cells and promote hypertension

(2014) Annet Kirabo et al.   JOURNAL OF CLINICAL INVESTIGATION

Adalimumab monotherapy versus combination therapy with immunomodulators in patients with Crohn's disease: A systematic review and meta-analysis

(2014) Uri Kopylov et al.   Journal of Crohns & Colitis

An imbalance in serum concentrations of inflammatory and anti-inflammatory cytokines in hypertension

(2014) Seyed Reza Mirhafez et al.   Journal of the American Society of Hypertension

Brodalumab, an Anti-IL17RA Monoclonal Antibody, in Psoriatic Arthritis

(2014) Philip J. Mease et al.   NEW ENGLAND JOURNAL OF MEDICINE

Secukinumab in Plaque Psoriasis — Results of Two Phase 3 Trials

(2014) Richard G. Langley et al.   NEW ENGLAND JOURNAL OF MEDICINE

Angiotensin II–Induced Vascular Dysfunction Depends on Interferon-γ–Driven Immune Cell Recruitment and Mutual Activation of Monocytes and NK-Cells

(2013) Sabine Kossmann et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Inflammation and Mechanical Stretch Promote Aortic Stiffening in Hypertension Through Activation of p38 Mitogen-Activated Protein Kinase

(2013) Jing Wu et al.   CIRCULATION RESEARCH

Immunosenescent CD8 + T Cells and C-X-C Chemokine Receptor Type 3 Chemokines Are Increased in Human Hypertension

(2013) Jong-Chan Youn et al.   HYPERTENSION

Deficiency of the Interleukin 17/23 Axis Accelerates Renal Injury in Mice With Deoxycorticosterone Acetate+Angiotensin II–Induced Hypertension

(2013) Christian F. Krebs et al.   HYPERTENSION

Autoimmune effector memory T cells: the bad and the good

(2013) Priyadharshini Devarajan et al.   IMMUNOLOGIC RESEARCH

Markers of Inflammation, Endothelial Activation, and Arterial Stiffness in Hypertensive Heart Disease and the Effects of Treatment

(2013) Andreas Jekell et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY

B7 family checkpoint regulators in immune regulation and disease

(2013) Sabrina Ceeraz et al.   TRENDS IN IMMUNOLOGY

The Immune System: Role in Hypertension

(2012) Ernesto L. Schiffrin   CANADIAN JOURNAL OF CARDIOLOGY

Interleukin-17 causes Rho-kinase-mediated endothelial dysfunction and hypertension

(2012) Hoanglan Nguyen et al.   CARDIOVASCULAR RESEARCH

Interferon-γ Signaling Inhibition Ameliorates Angiotensin II–Induced Cardiac Damage

(2012) Lajos Markó et al.   HYPERTENSION

Induction of Endothelial Nitric Oxide Synthase Expression by IL-17 in Human Vascular Endothelial Cells: Implications for Vascular Remodeling in Transplant Vasculopathy

(2012) A. C. Liu et al.   JOURNAL OF IMMUNOLOGY

A comparative risk assessment of burden of disease and injury attributable to 67 risk factors and risk factor clusters in 21 regions, 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010

(2012) Stephen S Lim et al.   LANCET

Adult-Onset Immunodeficiency in Thailand and Taiwan

(2012) Sarah K. Browne et al.   NEW ENGLAND JOURNAL OF MEDICINE

Immune Mechanisms in Hypertension

(2011) Avshalom Leibowitz et al.   CURRENT HYPERTENSION REPORTS

T Regulatory Lymphocytes Prevent Angiotensin II–Induced Hypertension and Vascular Injury

(2011) Tlili Barhoumi et al.   HYPERTENSION

Vascular Remodeling in Hypertension

(2011) Ernesto L. Schiffrin   HYPERTENSION

T Regulatory Lymphocytes Prevent Aldosterone-Induced Vascular Injury

(2011) Daniel A. Kasal et al.   HYPERTENSION

Relationship of IgG and IgM autoantibodies and immune complexes to oxidized LDL with markers of oxidation and inflammation and cardiovascular events: results from the EPIC-Norfolk Study

(2011) Amir Ravandi et al.   JOURNAL OF LIPID RESEARCH

Mechanisms Underlying Lineage Commitment and Plasticity of Helper CD4+ T Cells

(2010) J. J. O'Shea et al.   SCIENCE

Interleukin-17 and Interferon-γ Are Produced Concomitantly by Human Coronary Artery–Infiltrating T Cells and Act Synergistically on Vascular Smooth Muscle Cells

(2009) Raymond E. Eid et al.   CIRCULATION

Interleukin 17 Promotes Angiotensin II–Induced Hypertension and Vascular Dysfunction

(2009) Meena S. Madhur et al.   HYPERTENSION

Interleukin-17-Producing γδ T Cells Selectively Expand in Response to Pathogen Products and Environmental Signals

(2009) Bruno Martin et al.   IMMUNITY

Interleukin-1 and IL-23 Induce Innate IL-17 Production from γδ T Cells, Amplifying Th17 Responses and Autoimmunity

(2009) Caroline E. Sutton et al.   IMMUNITY

CD27 is a thymic determinant of the balance between interferon-γ- and interleukin 17–producing γδ T cell subsets

(2009) Julie C Ribot et al.   NATURE IMMUNOLOGY