Clinicopathological characterization of chronic lymphocytic leukemia with MYD88 mutations: L265P and non-L265P mutations are associated with different features

Routine sequencing in CLL has prognostic implications and provides new insight into pathogenesis and targeted treatments

(2019) Boyu Hu et al.   BRITISH JOURNAL OF HAEMATOLOGY

Immunohistochemistry Innovations for Diagnosis and Tissue-Based Biomarker Detection

(2019) Narittee Sukswai et al.   Current Hematologic Malignancy Reports

Chronic lymphocytic leukemia with proliferation centers in bone marrow is associated with younger age at initial presentation, complex karyotype and TP53 disruption

(2018) Sofia Garces et al.   HUMAN PATHOLOGY

Clinical utility of recently identified diagnostic, prognostic, and predictive molecular biomarkers in mature B-cell neoplasms

(2017) Arantza Onaindia et al.   MODERN PATHOLOGY

MYD88 mutations predict unfavorable prognosis in Chronic Lymphocytic Leukemia patients with mutated IGHV gene

(2017) Shu-Chao Qin et al.   Blood Cancer Journal

Clinical impact of MYD88 mutations in chronic lymphocytic leukemia

(2016) A. Martinez-Trillos et al.   BLOOD

Should IGHV status and FISH testing be performed in all CLL patients at diagnosis? A systematic review and meta-analysis

(2016) S. A. Parikh et al.   BLOOD

Biological and Clinical Relevance of Associated Genomic Alterations in MYD88 L265P and non-L265P–Mutated Diffuse Large B-Cell Lymphoma: Analysis of 361 Cases

(2016) Sydney Dubois et al.   CLINICAL CANCER RESEARCH

MYD88 L265P Mutations, But No Other Variants, Identify a Subpopulation of DLBCL Patients of Activated B-cell Origin, Extranodal Involvement, and Poor Outcome

(2016) J. Rovira et al.   CLINICAL CANCER RESEARCH

Genetic characterization of MYD88-mutated lymphoplasmacytic lymphoma in comparison with MYD88-mutated chronic lymphocytic leukemia

(2016) C Baer et al.   LEUKEMIA

Prognostic relevance of MYD88 mutations in CLL: the jury is still out

(2015) P. Baliakas et al.   BLOOD

Non-coding recurrent mutations in chronic lymphocytic leukaemia

(2015) Xose S. Puente et al.   NATURE

Mutations driving CLL and their evolution in progression and relapse

(2015) Dan A. Landau et al.   NATURE

Frequencies of SF3B1, NOTCH1, MYD88, BIRC3 and IGHV mutations and TP53 disruptions in Chinese with chronic lymphocytic leukemia: disparities with Europeans

(2015) Yi Xia et al.   Oncotarget

Somatic mutations in MYD88 and CXCR4 are determinants of clinical presentation and overall survival in Waldenstrom macroglobulinemia

(2014) S. P. Treon et al.   BLOOD

Mutations in TLR/MYD88 pathway identify a subset of young chronic lymphocytic leukemia patients with favorable outcome

(2014) A. Martinez-Trillos et al.   BLOOD

The genomic landscape of Waldenstrom macroglobulinemia is characterized by highly recurring MYD88 and WHIM-like CXCR4 mutations, and small somatic deletions associated with B-cell lymphomagenesis

(2013) Z. R. Hunter et al.   BLOOD

Evolution and Impact of Subclonal Mutations in Chronic Lymphocytic Leukemia

(2013) Dan A. Landau et al.   CELL

SF3B1 mutations correlated to cytogenetics and mutations in NOTCH1, FBXW7, MYD88, XPO1 and TP53 in 1160 untreated CLL patients

(2013) S Jeromin et al.   LEUKEMIA

Preservation of lower incidence of chronic lymphocytic leukemia in Chinese residents in British Columbia: a 26-year survey from 1983 to 2008

(2013) Vivien Mak et al.   LEUKEMIA & LYMPHOMA

Integrated mutational and cytogenetic analysis identifies new prognostic subgroups in chronic lymphocytic leukemia

(2012) D. Rossi et al.   BLOOD

MYD88 L265P Somatic Mutation in Waldenström's Macroglobulinemia

(2012) Steven P. Treon et al.   NEW ENGLAND JOURNAL OF MEDICINE

Whole-genome sequencing identifies recurrent mutations in chronic lymphocytic leukaemia

(2011) Xose S. Puente et al.   NATURE

SF3B1and Other Novel Cancer Genes in Chronic Lymphocytic Leukemia

(2011) Lili Wang et al.   NEW ENGLAND JOURNAL OF MEDICINE

Oncogenically active MYD88 mutations in human lymphoma

(2010) Vu N. Ngo et al.   NATURE

Helical assembly in the MyD88–IRAK4–IRAK2 complex in TLR/IL-1R signalling

(2010) Su-Chang Lin et al.   NATURE

Chemoimmunotherapy of chronic lymphocytic leukemia

(2010) Constantine S. Tam et al.   Nature Reviews Clinical Oncology

Prognostic factors in chronic lymphocytic leukemia—what do we need to know?

(2010) Paula Cramer et al.   Nature Reviews Clinical Oncology

Guidelines for the diagnosis and treatment of chronic lymphocytic leukemia: a report from the International Workshop on Chronic Lymphocytic Leukemia updating the National Cancer Institute-Working Group 1996 guidelines

(2008) M. Hallek et al.   BLOOD