Mitochondrial Targeting of the Enteropathogenic Escherichia coli Map Triggers Calcium Mobilization, ADAM10-MAP Kinase Signaling, and Host Cell Apoptosis

The bacterial metalloprotease NleD selectively cleaves mitogen-activated protein kinases that have high flexibility in their activation loop

(2020) Lihi Gur-Arie et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Enteropathogenic Escherichia coli remodels host endosomes to promote endocytic turnover and breakdown of surface polarity

(2019) Ephrem G. Kassa et al.   PLoS Pathogens

EspH suppresses Erk by spatial segregation from CD81 tetraspanin microdomains

(2018) Rachana Pattani Ramachandran et al.   INFECTION AND IMMUNITY

Host Cell Targeting by Enteropathogenic Bacteria T3SS Effectors

(2018) Laurie Pinaud et al.   TRENDS IN MICROBIOLOGY

Colonocyte metabolism shapes the gut microbiota

(2018) Yael Litvak et al.   SCIENCE

Control of cell death and mitochondrial fission by ERK1/2 MAP kinase signalling

(2017) Simon J. Cook et al.   FEBS Journal

Pseudomonas aeruginosa ExlA and Serratia marcescens ShlA trigger cadherin cleavage by promoting calcium influx and ADAM10 activation

(2017) Emeline Reboud et al.   PLoS Pathogens

Dissecting the role of ADAM10 as a mediator of Staphylococcus aureus  -toxin action

(2016) G. von Hoven et al.   BIOCHEMICAL JOURNAL

Type Three Secretion System in Attaching and Effacing Pathogens

(2016) Meztlli O. Gaytán et al.   Frontiers in Cellular and Infection Microbiology

Enteropathogenic Escherichia coli: foe or innocent bystander?

(2015) J. Hu et al.   CLINICAL MICROBIOLOGY AND INFECTION

The Cytoplasmic Domain of A Disintegrin and Metalloproteinase 10 (ADAM10) Regulates Its Constitutive Activity but Is Dispensable for Stimulated ADAM10-dependent Shedding

(2015) Thorsten Maretzky et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Expression of Enteropathogenic Escherichia coli Map Is Significantly Different than That of Other Type III Secreted EffectorsIn Vivo

(2014) Mai Nguyen et al.   INFECTION AND IMMUNITY

Functional Roles of p38 Mitogen-Activated Protein Kinase in Macrophage-Mediated Inflammatory Responses

(2014) Yanyan Yang et al.   MEDIATORS OF INFLAMMATION

The Salmonella Kinase SteC Targets the MAP Kinase MEK to Regulate the Host Actin Cytoskeleton

(2012) Charlotte Odendall et al.   Cell Host & Microbe

The enteropathogenic E. coli effector EspH promotes actin pedestal formation and elongation via WASP-interacting protein (WIP)

(2012) Alexander R. C. Wong et al.   CELLULAR MICROBIOLOGY

The Enteropathogenic Escherichia coli-Secreted Protein EspZ Inhibits Host Cell Apoptosis

(2012) Jennifer Lising Roxas et al.   INFECTION AND IMMUNITY

NIH Image to ImageJ: 25 years of image analysis

(2012) Caroline A Schneider et al.   NATURE METHODS

The Interplay between the Escherichia coli Rho Guanine Nucleotide Exchange Factor Effectors and the Mammalian RhoGEF Inhibitor EspH

(2012) A. R. C. Wong et al.   mBio

Cell death and infection: A double-edged sword for host and pathogen survival

(2011) Hiroshi Ashida et al.   JOURNAL OF CELL BIOLOGY

The MAPK cascades: Signaling components, nuclear roles and mechanisms of nuclear translocation

(2010) Alexander Plotnikov et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

How ERK1/2 activation controls cell proliferation and cell death: Is subcellular localization the answer?

(2010) Yohannes Mebratu et al.   CELL CYCLE

A bacterial effector targets host DH-PH domain RhoGEFs and antagonizes macrophage phagocytosis

(2010) Na Dong et al.   EMBO JOURNAL

N-Terminal Type III Secretion Signal of Enteropathogenic Escherichia coli Translocator Proteins

(2010) D. Munera et al.   JOURNAL OF BACTERIOLOGY

The effector repertoire of enteropathogenic E. coli: ganging up on the host cell

(2009) Paul Dean et al.   CURRENT OPINION IN MICROBIOLOGY

ERK and cell death: Mechanisms of ERK-induced cell death - apoptosis, autophagy and senescence

(2009) Sebastien Cagnol et al.   FEBS Journal

Structural insights into host GTPase isoform selection by a family of bacterial GEF mimics

(2009) Zhiwei Huang et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The mechanisms used by enteropathogenicEscherichia colito control filopodia dynamics

(2008) Cedric N. Berger et al.   CELLULAR MICROBIOLOGY

Ca2+ Signaling, Mitochondria and Cell Death

(2008) Paolo Pinton et al.   CURRENT MOLECULAR MEDICINE

Characterization of Ser338Phosphorylation for Raf-1 Activation

(2008) Mengwei Zang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Calcium and apoptosis: ER-mitochondria Ca2+ transfer in the control of apoptosis

(2008) P Pinton et al.   ONCOGENE

Mitochondria: The Hub of Cellular Ca2+ Signaling

(2008) György Szabadkai et al.   PHYSIOLOGY