Ex vivo Improvement of a von Willebrand Disease Type 2A Phenotype Using an Allele-Specific Small-Interfering RNA

The heparin binding domain of von Willebrand factor binds to growth factors and promotes angiogenesis in wound healing

(2019) Jun Ishihara et al.   BLOOD

Evolution of replacement therapy for von Willebrand dicsease: From plasma fraction to recombinant von Willebrand factor

(2019) Flora Peyvandi et al.   BLOOD REVIEWS

Effect of Sugar 2′,4′-Modifications on Gene Silencing Activity of Small Interfering RNA Duplexes

(2019) Elise Malek-Adamian et al.   Nucleic Acid Therapeutics

Variability of von Willebrand factor‐related parameters in endothelial colony forming cells

(2019) Annika Jong et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

How I manage severe von Willebrand disease

(2019) Frank W. G. Leebeek et al.   BRITISH JOURNAL OF HAEMATOLOGY

How I treat type 2B von Willebrand disease

(2018) Rebecca Kruse-Jarres et al.   BLOOD

Correction of a dominant-negative von Willebrand factor multimerization defect by small interfering RNA-mediated allele-specific inhibition of mutant von Willebrand factor

(2018) A. de Jong et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Patisiran, an RNAi Therapeutic, for Hereditary Transthyretin Amyloidosis

(2018) David Adams et al.   NEW ENGLAND JOURNAL OF MEDICINE

von Willebrand factor and inflammation

(2017) C. Kawecki et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Targeting of Antithrombin in Hemophilia A or B with RNAi Therapy

(2017) K. John Pasi et al.   NEW ENGLAND JOURNAL OF MEDICINE

Inclisiran in Patients at High Cardiovascular Risk with Elevated LDL Cholesterol

(2017) Kausik K. Ray et al.   NEW ENGLAND JOURNAL OF MEDICINE

Angiodysplasia in von Willebrand Disease: Understanding the Clinical and Basic Science

(2017) Soundarya Selvam et al.   SEMINARS IN THROMBOSIS AND HEMOSTASIS

Endothelial Progenitors: A Consensus Statement on Nomenclature

(2017) Reinhold J. Medina et al.   Stem Cells Translational Medicine

Von Willebrand’s Disease

(2016) Frank W.G. Leebeek et al.   NEW ENGLAND JOURNAL OF MEDICINE

Von Willebrand factor (Vonvendi®): the first recombinant product licensed for the treatment of von Willebrand disease

(2016) Massimo Franchini et al.   Expert Review of Hematology

von Willebrand factor is dimerized by protein disulfide isomerase

(2015) Svenja Lippok et al.   BLOOD

A global reference for human genetic variation

(2015) Richard A. Gibbs et al.   NATURE

von Willebrand factor, Jedi knight of the bloodstream

(2014) T. A. Springer   BLOOD

A Two-Tier Golgi-Based Control of Organelle Size Underpins the Functional Plasticity of Endothelial Cells

(2014) Francesco Ferraro et al.   DEVELOPMENTAL CELL

Delivery of Therapeutic siRNA to the Lung Endothelium via Novel Lipoplex Formulation DACC

(2014) V Fehring et al.   MOLECULAR THERAPY

In vivo endothelial siRNA delivery using polymeric nanoparticles with low molecular weight

(2014) James E. Dahlman et al.   Nature Nanotechnology

Gastrointestinal angiodysplasia and bleeding in von Willebrand disease

(2014) Massimo Franchini et al.   THROMBOSIS AND HAEMOSTASIS

Collagen Binding Provides a Sensitive Screen for Variant von Willebrand Disease

(2013) V. H. Flood et al.   CLINICAL CHEMISTRY

Establishment of outgrowth endothelial cells from peripheral blood

(2012) Javier Martin-Ramirez et al.   Nature Protocols

Determinants of bleeding phenotype in adult patients with moderate or severe von Willebrand disease

(2012) Eva M. de Wee et al.   THROMBOSIS AND HAEMOSTASIS

The dominant-negative von Willebrand factor gene deletion p.P1127_C1948delinsR: molecular mechanism and modulation

(2010) C. Casari et al.   BLOOD

A cluster of mutations in the D3 domain of von Willebrand factor correlates with a distinct subgroup of von Willebrand disease: type 2A/IIE

(2010) R. Schneppenheim et al.   BLOOD

Endothelial von Willebrand factor regulates angiogenesis

(2010) R. D. Starke et al.   BLOOD

Response to desmopressin is influenced by the genotype and phenotype in type 1 von Willebrand disease (VWD): results from the European Study MCMDM-1VWD

(2008) G. Castaman et al.   BLOOD