A Comparative In Vitro Study of the Neuroprotective Effect Induced by Cannabidiol, Cannabigerol, and Their Respective Acid Forms: Relevance of the 5-HT1A Receptors

Cannabidiol attenuates behavioral changes in a rodent model of schizophrenia through 5-HT1A, but not CB1 and CB2 receptors

(2020) Naielly Rodrigues da Silva et al.   PHARMACOLOGICAL RESEARCH

From Cannabis sativa to Cannabidiol: Promising Therapeutic Candidate for the Treatment of Neurodegenerative Diseases

(2020) Tommaso Cassano et al.   Frontiers in Pharmacology

Neuroprotective and Neuromodulatory Effects Induced by Cannabidiol and Cannabigerol in Rat Hypo-E22 cells and Isolated Hypothalamus

(2020) Viviana di Giacomo et al.   Antioxidants

Antioxidant and Neuroprotective Effects Induced by Cannabidiol and Cannabigerol in Rat CTX-TNA2 Astrocytes and Isolated Cortexes

(2020) Viviana di Giacomo et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Cannabidiol Prevents the Expression of the Locomotor Sensitization and the Metabolic Changes in the Nucleus Accumbens and Prefrontal Cortex Elicited by the Combined Administration of Cocaine and Caffeine in Rats

(2020) José Pedro Prieto et al.   NEUROTOXICITY RESEARCH

Biological potential of varinic-, minor-, and acidic phytocannabinoids

(2020) Rafael Franco et al.   PHARMACOLOGICAL RESEARCH

Pharmacological data of cannabidiol- and cannabigerol-type phytocannabinoids acting on cannabinoid CB1, CB2 and CB1/CB2 heteromer receptors

(2020) Gemma Navarro et al.   PHARMACOLOGICAL RESEARCH

Cannabidiol Treatment Might Promote Resilience to Cocaine and Methamphetamine Use Disorders: A Review of Possible Mechanisms

(2019) Claudia Calpe-López et al.   MOLECULES

Antioxidant Therapies for Neuroprotection-A Review

(2019) Teleanu et al.   Journal of Clinical Medicine

Nicotine-Induced Neuroprotection in Rotenone In Vivo and In Vitro Models of Parkinson’s Disease: Evidences for the Involvement of the Labile Iron Pool Level as the Underlying Mechanism

(2018) Camila Mouhape et al.   NEUROTOXICITY RESEARCH

Cannabidiol as a Promising Strategy to Treat and Prevent Movement Disorders?

(2018) Fernanda F. Peres et al.   Frontiers in Pharmacology

Cannabigerol Action at Cannabinoid CB1 and CB2 Receptors and at CB1–CB2 Heteroreceptor Complexes

(2018) Gemma Navarro et al.   Frontiers in Pharmacology

Cannabidiol skews biased agonism at cannabinoid CB1 and CB2 receptors with smaller effect in CB1-CB2 heteroreceptor complexes

(2018) Gemma Navarro et al.   BIOCHEMICAL PHARMACOLOGY

The respiratory chain inhibitor rotenone affects peroxisomal dynamics via its microtubule-destabilising activity

(2017) Josiah B. Passmore et al.   HISTOCHEMISTRY AND CELL BIOLOGY

Pathology of Neurodegenerative Diseases

(2017) Brittany N. Dugger et al.   Cold Spring Harbor Perspectives in Biology

Binding and Signaling Studies Disclose a Potential Allosteric Site for Cannabidiol in Cannabinoid CB2 Receptors

(2017) Eva Martínez-Pinilla et al.   Frontiers in Pharmacology

Vitamin K2 suppresses rotenone-induced microglial activation in vitro

(2016) Yan-xia Yu et al.   ACTA PHARMACOLOGICA SINICA

Cannabidiol attenuates haloperidol-induced catalepsy and c-Fos protein expression in the dorsolateral striatum via 5-HT1A receptors in mice

(2016) Andreza B. Sonego et al.   BEHAVIOURAL BRAIN RESEARCH

An update on PPAR activation by cannabinoids

(2016) Saoirse Elizabeth O'Sullivan   BRITISH JOURNAL OF PHARMACOLOGY

Cannabidiol protects an in vitro model of the blood-brain barrier from oxygen-glucose deprivation via PPARγ and 5-HT1A receptors

(2016) William H Hind et al.   BRITISH JOURNAL OF PHARMACOLOGY

Cannabidiol induces rapid-acting antidepressant-like effects and enhances cortical 5-HT/glutamate neurotransmission: role of 5-HT1A receptors

(2016) Raquel Linge et al.   NEUROPHARMACOLOGY

Cannabidiol, neuroprotection and neuropsychiatric disorders

(2016) Alline C. Campos et al.   PHARMACOLOGICAL RESEARCH

Endocannabinoids and endocannabinoid-related mediators: Targets, metabolism and role in neurological disorders

(2016) Fabio Arturo Iannotti et al.   PROGRESS IN LIPID RESEARCH

Cannabis sativa: The Plant of the Thousand and One Molecules

(2016) Christelle M. Andre et al.   Frontiers in Plant Science

Cannabidiol is a negative allosteric modulator of the cannabinoid CB1 receptor

(2015) R B Laprairie et al.   BRITISH JOURNAL OF PHARMACOLOGY

The Endocannabinoid System and its Modulation by Phytocannabinoids

(2015) Vincenzo Di Marzo et al.   Neurotherapeutics

Antidepressant-Like and Anxiolytic-Like Effects of Cannabidiol: A Chemical Compound of Cannabis sativa

(2014) Alexandre Schier et al.   CNS & Neurological Disorders-Drug Targets

Neuroprotective Properties of Cannabigerol in Huntington’s Disease: Studies in R6/2 Mice and 3-Nitropropionate-lesioned Mice

(2014) Sara Valdeolivas et al.   Neurotherapeutics

Effects of cannabidiol on the function of α7-nicotinic acetylcholine receptors

(2013) Mohamed Mahgoub et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Mechanisms of cannabidiol neuroprotection in hypoxic–ischemic newborn pigs: Role of 5HT1A and CB2 receptors

(2013) M. Ruth Pazos et al.   NEUROPHARMACOLOGY

Astrocyte Activation: A Key Step in Rotenone Induced Cytotoxicity and DNA Damage

(2012) Supriya Swarnkar et al.   NEUROCHEMICAL RESEARCH

Effects of cannabinoids Δ(9)-tetrahydrocannabinol, Δ(9)-tetrahydrocannabinolic acid and cannabidiol in MPP+ affected murine mesencephalic cultures

(2012) Rudolf Moldzio et al.   PHYTOMEDICINE

Distinct Effects of Rotenone, 1-methyl-4-phenylpyridinium and 6-hydroxydopamine on Cellular Bioenergetics and Cell Death

(2012) Samantha Giordano et al.   PLoS One

Hydrogen Peroxide as a Signaling Molecule

(2011) Elizabeth Veal et al.   ANTIOXIDANTS & REDOX SIGNALING

Cannabidiol, a non-psychotropic component of cannabis, attenuates vomiting and nausea-like behaviour via indirect agonism of 5-HT1A somatodendritic autoreceptors in the dorsal raphe nucleus

(2011) EM Rock et al.   BRITISH JOURNAL OF PHARMACOLOGY

Cost of disorders of the brain in Europe 2010

(2011) Anders Gustavsson et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

Oxidative stress in health and disease: The therapeutic potential of Nrf2 activation

(2011) Brooks M. Hybertson et al.   MOLECULAR ASPECTS OF MEDICINE

Phytocannabinoids as novel therapeutic agents in CNS disorders

(2011) Andrew J. Hill et al.   PHARMACOLOGY & THERAPEUTICS

Mechanisms Underlying Inflammation in Neurodegeneration

(2010) Christopher K. Glass et al.   CELL

After cellular internalization, quercetin causes Nrf2 nuclear translocation, increases glutathione levels, and prevents neuronal death against an oxidative insult

(2010) Florencia Arredondo et al.   FREE RADICAL BIOLOGY AND MEDICINE

Inflammation in neurodegenerative diseases

(2010) Sandra Amor et al.   IMMUNOLOGY

Pretreatment with Natural Flavones and Neuronal Cell Survival after Oxidative Stress: A Structure−Activity Relationship Study

(2010) Carolina Echeverry et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

5-HT1Areceptors are involved in the cannabidiol-induced attenuation of behavioural and cardiovascular responses to acute restraint stress in rats

(2009) Leonardo B.M. Resstel et al.   BRITISH JOURNAL OF PHARMACOLOGY

Antidepressant-like effects of cannabidiol in mice: possible involvement of 5-HT1A receptors

(2009) TV Zanelati et al.   BRITISH JOURNAL OF PHARMACOLOGY

Oxidative stress in developmental brain disorders

(2009) Masaharu Hayashi   NEUROPATHOLOGY

Non-psychotropic plant cannabinoids: new therapeutic opportunities from an ancient herb

(2009) Angelo A. Izzo et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Secondary metabolism in cannabis

(2008) Isvett Josefina Flores-Sanchez et al.   PHYTOCHEMISTRY REVIEWS

Involvement of 5HT1A receptors in the anxiolytic-like effects of cannabidiol injected into the dorsolateral periaqueductal gray of rats

(2008) Alline Cristina Campos et al.   PSYCHOPHARMACOLOGY

The diverse CB1and CB2receptor pharmacology of three plant cannabinoids: Δ9-tetrahydrocannabinol, cannabidiol and Δ9-tetrahydrocannabivarin

(2007) R G Pertwee   BRITISH JOURNAL OF PHARMACOLOGY