Rerouting plant terpene biosynthesis enables momilactone pathway elucidation

Complete biosynthesis of cannabinoids and their unnatural analogues in yeast

(2019) Xiaozhou Luo et al.   NATURE

Momilactones A and B Are α-Amylase and α-Glucosidase Inhibitors

(2019) Nguyen Quan et al.   MOLECULES

Identification of key enzymes responsible for protolimonoid biosynthesis in plants: Opening the door to azadirachtin production

(2019) Hannah Hodgson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Repeated evolution of cytochrome P450-mediated spiroketal steroid biosynthesis in plants

(2019) Bastien Christ et al.   Nature Communications

Complete biosynthesis of noscapine and halogenated alkaloids in yeast

(2018) Yanran Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Missing enzymes in the biosynthesis of the anticancer drug vinblastine in Madagascar periwinkle

(2018) Lorenzo Caputi et al.   SCIENCE

A translational synthetic biology platform for rapid access to gram-scale quantities of novel drug-like molecules

(2017) James Reed et al.   METABOLIC ENGINEERING

Total biosynthesis of the cyclic AMP booster forskolin from Coleus forskohlii

(2017) Irini Pateraki et al.   eLife

LOCALIZER: subcellular localization prediction of both plant and effector proteins in the plant cell

(2017) Jana Sperschneider et al.   Scientific Reports

Expanding the Landscape of Diterpene Structural Diversity through Stereochemically Controlled Combinatorial Biosynthesis

(2016) Johan Andersen-Ranberg et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Trends in glyphosate herbicide use in the United States and globally

(2016) Charles M. Benbrook   Environmental Sciences Europe

Optimization of recombinant expression enables discovery of novel cytochrome P450 activity in rice diterpenoid biosynthesis

(2015) Naoki Kitaoka et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Monoterpene biosynthesis potential of plant subcellular compartments

(2015) Lemeng Dong et al.   NEW PHYTOLOGIST

Elucidation of the first committed step in betalain biosynthesis enables the heterologous engineering of betalain pigments in plants

(2015) Guy Polturak et al.   NEW PHYTOLOGIST

Completion of the seven-step pathway from tabersonine to the anticancer drug precursor vindoline and its assembly in yeast

(2015) Yang Qu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

De novo production of the plant-derived alkaloid strictosidine in yeast

(2015) Stephanie Brown et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Six enzymes from mayapple that complete the biosynthetic pathway to the etoposide aglycone

(2015) Warren Lau et al.   SCIENCE

Plant diterpene synthases: exploring modularity and metabolic diversity for bioengineering

(2015) Philipp Zerbe et al.   TRENDS IN BIOTECHNOLOGY

Manoyl Oxide (13R), the Biosynthetic Precursor of Forskolin, Is Synthesized in Specialized Root Cork Cells in Coleus forskohlii

(2014) I. Pateraki et al.   PLANT PHYSIOLOGY

The Role of Momilactones in Rice Allelopathy

(2013) Hisashi Kato-Noguchi et al.   JOURNAL OF CHEMICAL ECOLOGY

Steviol Glycosides: Chemical Diversity, Metabolism, and Function

(2013) Stijn Ceunen et al.   JOURNAL OF NATURAL PRODUCTS

High-level semi-synthetic production of the potent antimalarial artemisinin

(2013) C. J. Paddon et al.   NATURE

High-level diterpene production by transient expression in Nicotiana benthamiana

(2013) Kathleen Brückner et al.   Plant Methods

Characterization of CYP76M5–8 Indicates Metabolic Plasticity within a Plant Biosynthetic Gene Cluster

(2012) Qiang Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Absorption of momilactone A and B by Arabidopsis thaliana L. and the growth inhibitory effects

(2012) Hisashi Kato-Noguchi et al.   JOURNAL OF PLANT PHYSIOLOGY

Terpenoid biosynthesis in trichomes-current status and future opportunities

(2012) B. Markus Lange et al.   PLANT BIOTECHNOLOGY JOURNAL

CYP701A8: A Rice ent-Kaurene Oxidase Paralog Diverted to More Specialized Diterpenoid Metabolism

(2012) Q. Wang et al.   PLANT PHYSIOLOGY

The role of allelopathy in agricultural pest management

(2011) Muhammad Farooq et al.   PEST MANAGEMENT SCIENCE

Reconstitution of the Costunolide Biosynthetic Pathway in Yeast and Nicotiana benthamiana

(2011) Qing Liu et al.   PLoS One

Contribution of momilactone A and B to rice allelopathy

(2010) Hisashi Kato-Noguchi et al.   JOURNAL OF PLANT PHYSIOLOGY

Tissue-Adapted Invasion Strategies of the Rice Blast FungusMagnaporthe oryzae

(2010) Sylvain Marcel et al.   PLANT CELL

CYP99A3: functional identification of a diterpene oxidase from the momilactone biosynthetic gene cluster in rice

(2010) Qiang Wang et al.   PLANT JOURNAL

Nicotiana benthamiana as a Production Platform for Artemisinin Precursors

(2010) Teun W. J. M. van Herpen et al.   PLoS One

pEAQ: versatile expression vectors for easy and quick transient expression of heterologous proteins in plants

(2009) Frank Sainsbury et al.   PLANT BIOTECHNOLOGY JOURNAL

Diterpene Phytoalexins Are Biosynthesized in and Exuded from the Roots of Rice Seedlings

(2008) Tomonobu TOYOMASU et al.   BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY