标题
Cas9 gene therapy for Angelman syndrome traps Ube3a-ATS long non-coding RNA
作者
关键词
-
出版物
NATURE
Volume -, Issue -, Pages -
出版商
Springer Science and Business Media LLC
发表日期
2020-10-22
DOI
10.1038/s41586-020-2835-2
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- A bipartite boundary element restrictsUBE3Aimprinting to mature neurons
- (2019) Jack S. Hsiao et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Long-term evaluation of AAV-CRISPR genome editing for Duchenne muscular dystrophy
- (2019) Christopher E. Nelson et al. NATURE MEDICINE
- Loss of nuclear UBE3A causes electrophysiological and behavioral deficits in mice and is associated with Angelman syndrome
- (2019) Rossella Avagliano Trezza et al. NATURE NEUROSCIENCE
- Prenatal Treatment Path for Angelman Syndrome and Other Neurodevelopmental Disorders
- (2019) Mark J. Zylka Autism Research
- High levels of AAV vector integration into CRISPR-induced DNA breaks
- (2019) Killian S. Hanlon et al. Nature Communications
- A behavioral test battery for mouse models of Angelman syndrome: a powerful tool for testing drugs and novel Ube3a mutants
- (2018) Monica Sonzogni et al. Molecular Autism
- Alternative Polyadenylation Directs Tissue-Specific miRNA Targeting inCaenorhabditis elegansSomatic Tissues
- (2017) Stephen M. Blazie et al. GENETICS
- Alternative Polyadenylation Directs Tissue-Specific miRNA Targeting inCaenorhabditis elegansSomatic Tissues
- (2017) Stephen M. Blazie et al. GENETICS
- Autism spectrum disorder prevalence and associations with air concentrations of lead, mercury, and arsenic
- (2016) Aisha S. Dickerson et al. ENVIRONMENTAL MONITORING AND ASSESSMENT
- The search for true numbers of neurons and glial cells in the human brain: A review of 150 years of cell counting
- (2016) Christopher S. von Bartheld et al. JOURNAL OF COMPARATIVE NEUROLOGY
- Genome-scale deletion screening of human long non-coding RNAs using a paired-guide RNA CRISPR–Cas9 library
- (2016) Shiyou Zhu et al. NATURE BIOTECHNOLOGY
- Topoisomerase 1 Regulates Gene Expression in Neurons through Cleavage Complex-Dependent and -Independent Mechanisms
- (2016) Angela M. Mabb et al. PLoS One
- Ube3a reinstatement identifies distinct developmental windows in a murine Angelman syndrome model
- (2015) Sara Silva-Santos et al. JOURNAL OF CLINICAL INVESTIGATION
- In vivo genome editing using Staphylococcus aureus Cas9
- (2015) F. Ann Ran et al. NATURE
- Seizure-like activity in a juvenile Angelman syndrome mouse model is attenuated by reducingArcexpression
- (2015) Caleigh Mandel-Brehm et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Cas-OFFinder: a fast and versatile algorithm that searches for potential off-target sites of Cas9 RNA-guided endonucleases
- (2014) S. Bae et al. BIOINFORMATICS
- Highly restricted deletion of the SNORD116 region is implicated in Prader–Willi Syndrome
- (2014) Eric Bieth et al. EUROPEAN JOURNAL OF HUMAN GENETICS
- Improved vectors and genome-wide libraries for CRISPR screening
- (2014) Neville E Sanjana et al. NATURE METHODS
- A Quantitative Framework to Evaluate Modeling of Cortical Development by Neural Stem Cells
- (2014) Jason L. Stein et al. NEURON
- Small mosaic deletion encompassing the snoRNAs andSNURF-SNRPNresults in an atypical Prader-Willi syndrome phenotype
- (2013) Britt-Marie Anderlid et al. AMERICAN JOURNAL OF MEDICAL GENETICS PART A
- Topoisomerases facilitate transcription of long genes linked to autism
- (2013) Ian F. King et al. NATURE
- Truncation of Ube3a-ATS Unsilences Paternal Ube3a and Ameliorates Behavioral Defects in the Angelman Syndrome Mouse Model
- (2013) Linyan Meng et al. PLoS Genetics
- The SNORD115 (H/MBII-52) and SNORD116 (H/MBII-85) gene clusters at the imprinted Prader-Willi locus generate canonical box C/D snoRNAs
- (2012) M.-L. Bortolin-Cavaille et al. NUCLEIC ACIDS RESEARCH
- Topoisomerase inhibitors unsilence the dormant allele of Ube3a in neurons
- (2011) Hsien-Sung Huang et al. NATURE
- The snoRNA MBII-52 (SNORD 115) is processed into smaller RNAs and regulates alternative splicing
- (2010) Shivendra Kishore et al. HUMAN MOLECULAR GENETICS
- Loss of the imprinted snoRNA mbii-52 leads to increased 5htr2c pre-RNA editing and altered 5HT2CR-mediated behaviour
- (2009) Christine M. Doe et al. HUMAN MOLECULAR GENETICS
- A deletion of the HBII-85 class of small nucleolar RNAs (snoRNAs) is associated with hyperphagia, obesity and hypogonadism
- (2009) A. J. de Smith et al. HUMAN MOLECULAR GENETICS
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