标题
Synthetic group A streptogramin antibiotics that overcome Vat resistance
作者
关键词
-
出版物
NATURE
Volume 586, Issue 7827, Pages 145-150
出版商
Springer Science and Business Media LLC
发表日期
2020-09-24
DOI
10.1038/s41586-020-2761-3
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- OPLS3e: Extending Force Field Coverage for Drug-Like Small Molecules
- (2019) Katarina Roos et al. Journal of Chemical Theory and Computation
- A concise route to virginiamycin M2
- (2019) Qi Li et al. TETRAHEDRON
- Macromolecular structure determination using X-rays, neutrons and electrons: recent developments in Phenix
- (2019) Dorothee Liebschner et al. Acta Crystallographica Section D-Structural Biology
- Cryo-EM in drug discovery: achievements, limitations and prospects
- (2018) Jean-Paul Renaud et al. NATURE REVIEWS DRUG DISCOVERY
- cisTEM, user-friendly software for single-particle image processing
- (2018) Timothy Grant et al. eLife
- Antibiotic Resistance ABC-F Proteins: Bringing Target Protection into the Limelight
- (2018) Liam K. R. Sharkey et al. ACS Infectious Diseases
- Real-space refinement in PHENIX for cryo-EM and crystallography
- (2018) Pavel V. Afonine et al. Acta Crystallographica Section D-Structural Biology
- High resolution single particle cryo-electron microscopy using beam-image shift
- (2018) Anchi Cheng et al. JOURNAL OF STRUCTURAL BIOLOGY
- Improving Accuracy, Diversity, and Speed with Prime Macrocycle Conformational Sampling
- (2017) Dan Sindhikara et al. Journal of Chemical Information and Modeling
- Modular, Scalable Synthesis of Group A Streptogramin Antibiotics
- (2017) Qi Li et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Predictive compound accumulation rules yield a broad-spectrum antibiotic
- (2017) Michelle F. Richter et al. NATURE
- MotionCor2: anisotropic correction of beam-induced motion for improved cryo-electron microscopy
- (2017) Shawn Q Zheng et al. NATURE METHODS
- Madumycin II inhibits peptide bond formation by forcing the peptidyl transferase center into an inactive state
- (2017) Ilya A. Osterman et al. NUCLEIC ACIDS RESEARCH
- Mefloquine targets the Plasmodium falciparum 80S ribosome to inhibit protein synthesis
- (2017) Wilson Wong et al. Nature Microbiology
- Pristinamycin in the treatment of MSSA bone and joint infection
- (2016) Florent Valour et al. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
- A platform for the discovery of new macrolide antibiotics
- (2016) Ian B. Seiple et al. NATURE
- ABC-F Proteins Mediate Antibiotic Resistance through Ribosomal Protection
- (2016) Liam K. R. Sharkey et al. mBio
- High-resolution structure of the Escherichia coli ribosome
- (2015) Jonas Noeske et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- High-resolution structure of the Escherichia coli ribosome
- (2015) Jonas Noeske et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- The Evolving Role of Chemical Synthesis in Antibacterial Drug Discovery
- (2014) Peter M. Wright et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Synergy of Streptogramin Antibiotics Occurs Independently of Their Effects on Translation
- (2014) Jonas Noeske et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Potential for Reduction of Streptogramin A Resistance Revealed by Structural Analysis of Acetyltransferase VatA
- (2014) Peter J. Stogios et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- A proton wire to couple aminoacyl-tRNA accommodation and peptide-bond formation on the ribosome
- (2014) Yury S Polikanov et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Jaguar: A high-performance quantum chemistry software program with strengths in life and materials sciences
- (2013) Art D. Bochevarov et al. INTERNATIONAL JOURNAL OF QUANTUM CHEMISTRY
- Regio-selectively reduced streptogramin A analogue, 5,6-dihydrovirginiamycin M1exhibits improved potency against MRSA
- (2013) N.H. Hoang et al. LETTERS IN APPLIED MICROBIOLOGY
- Broad-substrate screen as a tool to identify substrates for bacterial Gcn5-relatedN-acetyltransferases with unknown substrate specificity
- (2012) Misty L. Kuhn et al. PROTEIN SCIENCE
- In vitro pharmacokinetic/pharmacodynamic activity of NXL103 versus clindamycin and linezolid against clinical Staphylococcus aureus and Streptococcus pyogenes isolates
- (2011) Celine Vidaillac et al. INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS
- Total Synthesis of (−)-Virginiamycin M2: Application of Crotylsilanes Accessed by Enantioselective Rh(II) or Cu(I) Promoted Carbenoid Si–H Insertion
- (2011) Jie Wu et al. JOURNAL OF ORGANIC CHEMISTRY
- The VSGB 2.0 model: A next generation energy model for high resolution protein structure modeling
- (2011) Jianing Li et al. PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS
- XDS
- (2010) Wolfgang Kabsch ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- Features and development ofCoot
- (2010) P. Emsley et al. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- Total Synthesis of (−)-Virginiamycin M2
- (2010) Jie Wu et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Binding and Action of CEM-101, a New Fluoroketolide Antibiotic That Inhibits Protein Synthesis
- (2010) B. Llano-Sotelo et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- electronic Ligand Builder and Optimization Workbench(eLBOW): a tool for ligand coordinate and restraint generation
- (2009) Nigel W. Moriarty et al. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- The A–Z of bacterial translation inhibitors
- (2009) Daniel N. Wilson CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY
- xia2: an expert system for macromolecular crystallography data reduction
- (2009) G. Winter JOURNAL OF APPLIED CRYSTALLOGRAPHY
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now