Three pleiotropic loci associated with bone mineral density and lean body mass

Joint Association Analysis Identified 18 New Loci for Bone Mineral Density

(2019) Yu-Fang Pei et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Two functional variants at 6p21.1 were associated with lean mass

(2019) Yu-Fang Pei et al.   Skeletal Muscle

Life-Course Genome-wide Association Study Meta-analysis of Total Body BMD and Assessment of Age-Specific Effects

(2018) Carolina Medina-Gomez et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Joint study of two genome-wide association meta-analyses identified 20p12.1 and 20q13.33 for bone mineral density

(2018) Yu-Fang Pei et al.   BONE

An atlas of genetic influences on osteoporosis in humans and mice

(2018) John A. Morris et al.   NATURE GENETICS

Identification of 153 new loci associated with heel bone mineral density and functional involvement of GPC6 in osteoporosis

(2017) John P Kemp et al.   NATURE GENETICS

Large meta-analysis of genome-wide association studies identifies five loci for lean body mass

(2017) M. Carola Zillikens et al.   Nature Communications

Bivariate genome-wide association meta-analysis of pediatric musculoskeletal traits reveals pleiotropic effects at the SREBF1/TOM1L2 locus

(2017) Carolina Medina-Gomez et al.   Nature Communications

3DSNP: a database for linking human noncoding SNPs to their three-dimensional interacting genes

(2016) Yiming Lu et al.   NUCLEIC ACIDS RESEARCH

Meta-analysis of Correlated Traits via Summary Statistics from GWASs with an Application in Hypertension

(2015) Xiaofeng Zhu et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Phosphoprotein phosphatase 1CB (PPP1CB), a novel adipogenic activator, promotes 3T3-L1 adipogenesis

(2015) Young-Lai Cho et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Osteoporosis and sarcopenia in older age

(2015) M.H. Edwards et al.   BONE

Bivariate Genome-Wide Association Study ImplicatesATP6V1G1as a Novel Pleiotropic Locus Underlying Osteoporosis and Age at Menarche

(2015) Li-Jun Tan et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Whole‐genome sequencing identifies EN1 as a determinant of bone density and fracture

(2015) Hou‐Feng Zheng et al.   NATURE

FISH: fast and accurate diploid genotype imputation via segmental hidden Markov model

(2014) Lei Zhang et al.   BIOINFORMATICS

Efficient multivariate linear mixed model algorithms for genome-wide association studies

(2014) Xiang Zhou et al.   NATURE METHODS

Meta-analysis of genome-wide association data identifies novel susceptibility loci for obesity

(2013) Y.-F. Pei et al.   HUMAN MOLECULAR GENETICS

Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture

(2013) Sonja I Berndt et al.   NATURE GENETICS

The association between fat and lean mass and bone mineral density: The Healthy Twin Study

(2012) Joo-Hyun Park et al.   BONE

Suggestion of GLYAT gene underlying variation of bone size and body lean mass as revealed by a bivariate genome-wide association study

(2012) Yan-Fang Guo et al.   HUMAN GENETICS

Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture

(2012) Karol Estrada et al.   NATURE GENETICS

Regulation of Lean Mass, Bone Mass, and Exercise Tolerance by the Central Melanocortin System

(2012) Theodore P. Braun et al.   PLoS One

Bivariate genome-wide association study suggests that the DARC gene influences lean body mass and age at menarche

(2012) Rong Hai et al.   Science China-Life Sciences

Genome-wide association study of copy number variation identified gremlin1 as a candidate gene for lean body mass

(2011) Rong Hai et al.   JOURNAL OF HUMAN GENETICS

Sarcopenia: An Undiagnosed Condition in Older Adults. Current Consensus Definition: Prevalence, Etiology, and Consequences. International Working Group on Sarcopenia

(2011) Roger A. Fielding et al.   Journal of the American Medical Directors Association

HaploReg: a resource for exploring chromatin states, conservation, and regulatory motif alterations within sets of genetically linked variants

(2011) L. D. Ward et al.   NUCLEIC ACIDS RESEARCH

Bivariate Genome-Wide Association Analyses of Femoral Neck Bone Geometry and Appendicular Lean Mass

(2011) Lu Sun et al.   PLoS One

Robust relationship inference in genome-wide association studies

(2010) Ani Manichaikul et al.   BIOINFORMATICS

Association between fat intake, physical activity and mortality depending on genetic variation in FTO

(2010) E Sonestedt et al.   INTERNATIONAL JOURNAL OF OBESITY

An investigation into the relationship between soft tissue body composition and bone mineral density in a young adult twin sample

(2010) Leonie H Bogl et al.   JOURNAL OF BONE AND MINERAL RESEARCH

An Association Test for Multiple Traits Based on the Generalized Kendall’s Tau

(2010) Heping Zhang et al.   JOURNAL OF THE AMERICAN STATISTICAL ASSOCIATION

Genome-wide Association and Replication Studies Identified TRHR as an Important Gene for Lean Body Mass

(2009) Xiao-Gang Liu et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Inactivation of the Fto gene protects from obesity

(2009) Julia Fischer et al.   NATURE

Powerful Bivariate Genome-Wide Association Analyses Suggest the SOX6 Gene Influencing Both Obesity and Osteoporosis Phenotypes in Males

(2009) Yao-Zhong Liu et al.   PLoS One

Sarcopenia: Its assessment, etiology, pathogenesis, consequences and future perspectives

(2008) Y. Rolland et al.   Journal of Nutrition Health & Aging