The overexpression of TDP-43 in astrocytes causes neurodegeneration via a PTP1B-mediated inflammatory response
出版年份 2020 全文链接
标题
The overexpression of TDP-43 in astrocytes causes neurodegeneration via a PTP1B-mediated inflammatory response
作者
关键词
-
出版物
Journal of Neuroinflammation
Volume 17, Issue 1, Pages -
出版商
Springer Science and Business Media LLC
发表日期
2020-10-14
DOI
10.1186/s12974-020-01963-6
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- (2019) Fredrik Bergenheim et al. Stem Cell Research & Therapy
- Energy metabolism in ALS: an underappreciated opportunity?
- (2018) Tijs Vandoorne et al. ACTA NEUROPATHOLOGICA
- Current anti-diabetic agents and their molecular targets: A review
- (2018) Nagaraju Kerru et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Astrocytes expressing ALS-linked mutant FUS induce motor neuron death through release of tumor necrosis factor-alpha
- (2018) Azadeh Kia et al. GLIA
- TDP-43 interacts with mitochondrial proteins critical for mitophagy and mitochondrial dynamics
- (2018) Stephani A. Davis et al. NEUROSCIENCE LETTERS
- Oxidative stress and altered mitochondrial protein expression in the absence of amyloid-β and tau pathology in iPSC-derived neurons from sporadic Alzheimer's disease patients
- (2018) Julian H. Birnbaum et al. Stem Cell Research
- Linking hnRNP Function to ALS and FTD Pathology
- (2018) Maria D. Purice et al. Frontiers in Neuroscience
- Role of Glial Immunity in Lifespan Determination: A Drosophila Perspective
- (2018) Ilias Kounatidis et al. Frontiers in Immunology
- Cerebrospinal Fluid Inflammatory Cytokine Aberrations in Alzheimer's Disease, Parkinson's Disease and Amyotrophic Lateral Sclerosis: A Systematic Review and Meta-Analysis
- (2018) Xi Chen et al. Frontiers in Immunology
- Extracellular TDP-43 aggregates target MAPK/MAK/MRK overlapping kinase (MOK) and trigger caspase-3/IL-18 signaling in microglia
- (2017) María M. Leal-Lasarte et al. FASEB JOURNAL
- Genetic mutations in RNA-binding proteins and their roles in ALS
- (2017) Katannya Kapeli et al. HUMAN GENETICS
- Mutant TDP-43 does not impair mitochondrial bioenergetics in vitro and in vivo
- (2017) Hibiki Kawamata et al. Molecular Neurodegeneration
- Neuroprotective Effects of Protein Tyrosine Phosphatase 1B Inhibition against ER Stress-Induced Toxicity
- (2017) Yu-Mi Jeon et al. MOLECULES AND CELLS
- Enhancing Mitofusin/Marf ameliorates neuromuscular dysfunction in Drosophila models of TDP-43 proteinopathies
- (2017) Bilal Khalil et al. NEUROBIOLOGY OF AGING
- Neuroprotection by IFN-γ via astrocyte-secreted IL-6 in acute neuroinflammation
- (2017) Lijie Sun et al. Oncotarget
- Inflammatory responses and inflammation-associated diseases in organs
- (2017) Linlin Chen et al. Oncotarget
- Retrotransposon activation contributes to neurodegeneration in a Drosophila TDP-43 model of ALS
- (2017) Lisa Krug et al. PLoS Genetics
- Sporadic ALS Astrocytes Induce Neuronal Degeneration In Vivo
- (2017) Kun Qian et al. Stem Cell Reports
- Deficiency of PTP1B Attenuates Hypothalamic Inflammation via Activation of the JAK2-STAT3 Pathway in Microglia
- (2017) Taku Tsunekawa et al. EBioMedicine
- Increased peripheral blood inflammatory cytokine levels in amyotrophic lateral sclerosis: a meta-analysis study
- (2017) Yang Hu et al. Scientific Reports
- A novel role for protein tyrosine phosphatase 1B as a positive regulator of neuroinflammation
- (2016) Gyun Jee Song et al. Journal of Neuroinflammation
- NSC-34 Motor Neuron-Like Cells Are Unsuitable as Experimental Model for Glutamate-Mediated Excitotoxicity
- (2016) Blandine Madji Hounoum et al. Frontiers in Cellular Neuroscience
- Attenuation of synaptic toxicity and MARK4/PAR1-mediated Tau phosphorylation by methylene blue for Alzheimer’s disease treatment
- (2016) Wenchao Sun et al. Scientific Reports
- From animal models to human disease: a genetic approach for personalized medicine in ALS
- (2016) Vincent Picher-Martel et al. Acta Neuropathologica Communications
- Comparative Analysis of Protein Tyrosine Phosphatases Regulating Microglial Activation
- (2016) Gyun Jee Song et al. Experimental Neurobiology
- TDP-43 activates microglia through NF-κB and NLRP3 inflammasome
- (2015) Weihua Zhao et al. EXPERIMENTAL NEUROLOGY
- TDP-43 Proteinopathy and ALS: Insights into Disease Mechanisms and Therapeutic Targets
- (2015) Emma L. Scotter et al. Neurotherapeutics
- DrosophilaCentral Nervous System Glia
- (2015) Marc R. Freeman Cold Spring Harbor Perspectives in Biology
- PPAR gamma activation is neuroprotective in a Drosophila model of ALS based on TDP-43
- (2014) Archi Joardar et al. HUMAN MOLECULAR GENETICS
- Opposing roles of p38 and JNK in a Drosophila model of TDP-43 proteinopathy reveal oxidative stress and innate immunity as pathogenic components of neurodegeneration
- (2014) Lihong Zhan et al. HUMAN MOLECULAR GENETICS
- Pivotal role of protein tyrosine phosphatase 1B (PTP1B) in the macrophage response to pro-inflammatory and anti-inflammatory challenge
- (2014) P G Través et al. Cell Death & Disease
- Motor neurons and glia exhibit specific individualized responses to TDP-43 expression in a Drosophila model of amyotrophic lateral sclerosis
- (2013) P. S. Estes et al. Disease Models & Mechanisms
- Expression of ALS-linked TDP-43 mutant in astrocytes causes non-cell-autonomous motor neuron death in rats
- (2013) Jianbin Tong et al. EMBO JOURNAL
- The ALS disease-associated mutant TDP-43 impairs mitochondrial dynamics and function in motor neurons
- (2013) Wenzhang Wang et al. HUMAN MOLECULAR GENETICS
- Therapeutic modulation of eIF2α phosphorylation rescues TDP-43 toxicity in amyotrophic lateral sclerosis disease models
- (2013) Hyung-Jun Kim et al. NATURE GENETICS
- Differentiated NSC-34 motoneuron-like cells as experimental model for cholinergic neurodegeneration
- (2013) Oliver Maier et al. NEUROCHEMISTRY INTERNATIONAL
- Mitochondrial dysfunctions in Parkinson's disease
- (2013) C.A. Gautier et al. REVUE NEUROLOGIQUE
- Mitochondrial dysfunction in human TDP-43 transfected NSC34 cell lines and the protective effect of dimethoxy curcumin
- (2012) Jinsheng Lu et al. BRAIN RESEARCH BULLETIN
- Altered astrocytic response to activation in SOD1G93Amice and its implications on amyotrophic lateral sclerosis pathogenesis
- (2012) Chen Benkler et al. GLIA
- A harmonized classification system for FTLD-TDP pathology
- (2011) Ian R. A. Mackenzie et al. ACTA NEUROPATHOLOGICA
- Assessing bioenergetic function in response to oxidative stress by metabolic profiling
- (2011) Brian P. Dranka et al. FREE RADICAL BIOLOGY AND MEDICINE
- Deregulation of TDP-43 in amyotrophic lateral sclerosis triggers nuclear factor κB–mediated pathogenic pathways
- (2011) Vivek Swarup et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Regulation of Choline Acetyltransferase Expression by 17β-Oestradiol in NSC-34 Cells and in the Spinal Cord
- (2011) S. Johann et al. JOURNAL OF NEUROENDOCRINOLOGY
- Accumulation of Transactive Response DNA Binding Protein 43 in Mild Cognitive Impairment and Alzheimer Disease
- (2011) Cyntia Tremblay et al. JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY
- SOD1 and TDP-43 animal models of amyotrophic lateral sclerosis: recent advances in understanding disease toward the development of clinical treatments
- (2011) Peter I. Joyce et al. MAMMALIAN GENOME
- Astrocytes from familial and sporadic ALS patients are toxic to motor neurons
- (2011) Amanda M Haidet-Phillips et al. NATURE BIOTECHNOLOGY
- Mitochondrial dysfunction in ALS
- (2011) Mauro Cozzolino et al. PROGRESS IN NEUROBIOLOGY
- TNFα increases hypothalamic PTP1B activity via the NFκB pathway in rat hypothalamic organotypic cultures
- (2011) Yoshihiro Ito et al. REGULATORY PEPTIDES
- Roles of activated astrocyte in neural stem cell proliferation and differentiation
- (2011) Fu-wu Wang et al. Stem Cell Research
- Wild-Type Human TDP-43 Expression Causes TDP-43 Phosphorylation, Mitochondrial Aggregation, Motor Deficits, and Early Mortality in Transgenic Mice
- (2010) Y.-F. Xu et al. JOURNAL OF NEUROSCIENCE
- A Drosophila model for TDP-43 proteinopathy
- (2010) Y. Li et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Altered distributions of Gemini of coiled bodies and mitochondria in motor neurons of TDP-43 transgenic mice
- (2010) X. Shan et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- TDP-43 transgenic mice develop spastic paralysis and neuronal inclusions characteristic of ALS and frontotemporal lobar degeneration
- (2010) Hans Wils et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Non–cell autonomous toxicity in neurodegenerative disorders: ALS and beyond
- (2009) Hristelina Ilieva et al. JOURNAL OF CELL BIOLOGY
- PTP1B is a negative regulator of interleukin 4-induced STAT6 signaling
- (2008) X. Lu et al. BLOOD
- Astrocytes as determinants of disease progression in inherited amyotrophic lateral sclerosis
- (2008) Koji Yamanaka et al. NATURE NEUROSCIENCE
- Development and Characterisation of a Glutamate-Sensitive Motor Neurone Cell Line
- (2003) Christopher J. Eggett et al. JOURNAL OF NEUROCHEMISTRY
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