Article
Chemistry, Multidisciplinary
Fang Lu, Yurong Ma, Hui Huang, Yue Zhang, Hui Kong, Yan Zhao, Huihua Qu, Qingguo Wang, Yang Liu, Zhenhui Kang
Summary: Research has found that semi-carbonized nanodots prepared from natural plants show good effectiveness in the treatment and inhibition of stress gastric ulcers, reducing inflammation and oxidative stress, protecting the gastric mucosa, and regulating neuroendocrine responses, energy metabolism, and intestinal flora structure, thereby alleviating the occurrence of stress-induced gastric ulcers.
Article
Chemistry, Multidisciplinary
Niall M. C. Mulkerns, William H. Hoffmann, Javier Ramos-Soriano, Noelia de la Cruz, Teodoro Garcia-Millan, Robert L. Harniman, Ian D. Lindsay, Annela M. Seddon, M. Carmen Galan, Henkjan Gersen
Summary: A practical method based on measuring the refractive index of nanoparticles in suspension is proposed for determining the ratio of functionalisation layer volume to particle volume. The method is successfully applied to different nanoparticles and shows the ability to detect differences in surface functionalisation or composition of nanosized particles. This non-destructive and rapid method is well-suited for industrial particle characterisation and biological applications.
Article
Chemistry, Multidisciplinary
Chun-Yan Shih, Wei-Lun Huang, I-Ting Chiang, Wu-Chou Su, Hsisheng Teng
Summary: Nitrogen-doped graphene oxide dots (NGODs) can serve as an efficient photosensitizer for Photodynamic therapy (PDT) by producing H2O2 under white-light irradiation in the presence of ascorbic acid (AA). The unique structure of NGODs restricts the transfer of photogenerated electrons for H2O2 production, showing high potential for effective and accurate deployment in PDT.
Article
Nanoscience & Nanotechnology
Wenyu Wang, Yang Zhu, Xiaorong Zhu, Yafei Zhao, Zhenggang Xue, Can Xiong, Zhiyuan Wang, Yunteng Qu, Junjie Cheng, Min Chen, Manman Liu, Fangyao Zhou, Haoran Zhang, Zheng Jiang, Yidong Hu, Huang Zhou, Huijuan Wang, Yafei Li, Yangzhong Liu, Yuen Wu
Summary: This study successfully constructed Ru single-atom enzymes with superior activity and stability by using carbon dots as the carrier material, leading to a lethal effect on cancer cells. The Ru single-atom enzymes exhibit excellent peroxidase-like activity, activating H2O2 to produce reactive oxygen species that cause damage to cancer cells.
ACS APPLIED MATERIALS & INTERFACES
(2021)
Article
Chemistry, Multidisciplinary
Arphaphon Sichamnan, Nararat Yong, Siwapech Sillapaprayoon, Wittaya Pimtong, I-Ming Tang, Weerakanya Maneeprakorn, Weeraphat Pon-On
Summary: Multifunctional biocompatible magneto-fluorescence nanoparticles were successfully fabricated in this study, showing great potential as a fluorescent sensor and for magnetic hyperthermia applications. The nanoparticles combine CoMnF@Si and fluorescent CDots, providing a versatile and non-toxic nanomaterial for various biomedical applications.
Article
Environmental Sciences
Trisita Ghosh, Suvendu Nandi, Swarup Krishna Bhattacharyya, Suman Kumar Ghosh, Mahitosh Mandal, Pallab Banerji, Narayan Ch Das
Summary: This study developed photoluminescent heteroatom-doped carbon dots for cancer cell imaging through a simple hydrothermal procedure. The carbon dots exhibited spherical shape with an average diameter of 3.5 nm. They showed low cytotoxicity and good compatibility with normal glial cells, and were able to emit green fluorescence inside cells with imaging-trackable ability.
ENVIRONMENTAL RESEARCH
(2023)
Article
Green & Sustainable Science & Technology
A. Khan, P. Ezati, J. -t. Kim, J. -w. Rhim
Summary: Carbon quantum dots (CQDs) are widely used in various industries due to their non-toxic, biocompatibility, antibacterial, and tunable photoluminescence properties. The integration of CQD sensing platforms with food packaging could provide a means to allow real-time monitoring of the quality change of packaged foods. This review summarizes recent research and developments on CQD-based sensors in the food industry and outlines the potential challenges and prospects of real-time intelligent sensing of food quality changes.
MATERIALS TODAY SUSTAINABILITY
(2023)
Article
Biotechnology & Applied Microbiology
Hailong Huang, Hao Ge, Zhipeng Ren, Zhijian Huang, Min Xu, Xianghui Wang
Summary: In this study, a series of carbon dots with different particle sizes and doped with elements were prepared using various pretreatment methods based on natural cellulose hydrogel. The smallest CD-4a showed potential for detecting Hg2+ with a detection limit of 0.2 μM.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2021)
Article
Biotechnology & Applied Microbiology
Xiaoke Wang, Tong Wu, Yingxin Yang, Long Zhou, Shuxian Wang, Jiaxing Liu, Yafang Zhao, Meiling Zhang, Yan Zhao, Huihua Qu, Hui Kong, Yue Zhang
Summary: This study demonstrates the potential of carbon dots derived from Pollen Typhae (PT-CDs) as a novel relieving strategy for acute kidney injury (AKI). PT-CDs showed significant activity in improving BUN and CRE levels, urine volume, kidney index, and histopathological morphology in a rat model of rhabdomyolysis-induced AKI. The interventions of PT-CDs also reduced inflammatory reaction and oxidative stress, which may contribute to their anti-AKI activities. Cytotoxicity assay and biosafety evaluation confirmed the high biocompatibility of PT-CDs.
JOURNAL OF NANOBIOTECHNOLOGY
(2023)
Article
Polymer Science
Monique Cotrim, Rodrigo Orefice
Summary: Carbon quantum dots (CDs) synthesized from silk by a microwave-assisted method were incorporated into PCL/silk matrix to create fluorescent nanofiber yarns. The inclusion of CDs not only imparted fluorescence to the yarns, but also led to a decrease in fiber diameter, an increase in strength, and good biocompatibility. These yarns have the potential for multifunctional applications in biotextiles, such as antiviral, antibacterial, and biosensing capabilities.
POLYMERS FOR ADVANCED TECHNOLOGIES
(2021)
Article
Spectroscopy
Asha Kumari, Arun Sharma, Rahul Sharma, Udayabanu Malairaman, Ragini Raj Singh
Summary: Fluorescent characteristics, cytotoxicity behavior, and antimicrobial activity of NIR-emitting CdTe QDs were extensively studied. Encapsulation with polymers prevents toxic consequences and allows easy modification according to biological environment, making these QDs suitable for bioimaging and distribution. The QDs showed attractive optical properties and demonstrated inhibition against bacterial strains.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2021)
Article
Agricultural Engineering
Seungjae Min, Parya Ezati, Jong-Whan Rhim
Summary: Carbon dots (CD) synthesized using hydrothermal method with potato peel as functional fillers were applied in food packaging films. The CD showed strong antioxidant and antimicrobial activity, low cytotoxicity, and improved properties of gelatin film. The CD-added gelatin films have great potential as a value-added, low-cost, safe, and functional nanofiller for packaging applications.
INDUSTRIAL CROPS AND PRODUCTS
(2022)
Article
Engineering, Environmental
Monikankana Saikia, Abhishek Hazarika, Kallol Roy, Puja Khare, Anjum Dihingia, Rituraj Konwar, Binoy K. Saikia
Summary: In this study, high quantum yield fluorescent carbon quantum dots (CQDs) were efficiently synthesized from petroleum coke and kitchen tea residues using a simple and environmentally friendly method. The resulting CQDs exhibited excellent water solubility, fluorescence properties, and biocompatibility. They also showed antioxidant properties and antibacterial effects against different bacterial strains. Moreover, the waste-derived CQDs were found to enhance plant growth, indicating their potential as nanofertilizers.
JOURNAL OF ENVIRONMENTAL CHEMICAL ENGINEERING
(2023)
Article
Food Science & Technology
Shanshan Mei, Bofei Fu, Xianjie Su, Hongbin Chen, Hetong Lin, Zongping Zheng, Congjie Dai, Da-Peng Yang
Summary: This study focuses on designing cost-effective and sustainable edible packaging films with multifunctional activities. By incorporating silk sericin, chitosan, and carbon dots, the bio-nanocomposite films demonstrated enhanced flexibility, antimicrobial, and antioxidant properties compared to films made solely of silk sericin. The components were well dispersed within the film matrix network, and the presence of carbon dots allowed the films to exhibit blue fluorescent emission, which could be used as an anticounterfeit label. Furthermore, the fruit-litchi test confirmed the effectiveness of the bio-nanocomposite film in preserving nutritional components. Overall, this study provides insights into the use of silk sericin and carbon dots for the preparation of environmentally friendly edible food packaging films and their application in effective fruit preservation.
LWT-FOOD SCIENCE AND TECHNOLOGY
(2022)
Article
Multidisciplinary Sciences
Savan K. Raj, Babita Choudhary, Anshul Yadav, Rajesh Patidar, Avinash Mishra, Vaibhav Kulshrestha
Summary: Brightly fluorescent Carbon Dots (CDs) were synthesized using green hydrothermal method. These CDs showed preferential interaction with Fe3+ and can act as nanoprobe for sensing Fe3+.
Article
Polymer Science
Sahin Demirci, S. Duygu Sutekin, Saliha B. Kurt, Olgun Guven, Nurettin Sahiner
Summary: PVAm microparticles were successfully synthesized using a unique method and treated with two different bifunctional crosslinkers. The effect of crosslinker types and pH on the hydrolytic degradation of PVAm particles was investigated, and blood compatibility of the particles was assessed. Furthermore, the antifungal and antibacterial efficacy of PVAm-based particles were tested against various yeast and bacterial strains.
Article
Engineering, Chemical
Sahin Demirci, Nurettin Sahiner
Summary: The concept of using a macroporous thermo-responsive polymer matrix for enzyme immobilization is explained. The immobilization of α-glucosidase within a p(NIPAM) cryogel is carried out under storage conditions, yielding high immobilization efficiency and activity recovery%. The prepared cryogel system exhibits better reuse and storage stability compared to native α-glucosidase enzyme.
CANADIAN JOURNAL OF CHEMICAL ENGINEERING
(2022)
Article
Engineering, Chemical
Sahin Demirci, Nurettin Sahiner
Summary: Cryogels are unique materials for enzyme immobilization due to their porous elastic structures and fast response times. This study focuses on the development of a p(Amphoteric) cryogel as a support for immobilizing α-Glucosidase enzyme. The cryogel exhibited high enzymatic activity, excellent pH tolerability, improved storage stability, and extraordinary reusability performances.
CHEMICAL ENGINEERING RESEARCH & DESIGN
(2022)
Article
Engineering, Electrical & Electronic
Sotir Sotirov, Sahin Demirci, Maria Marudova, Nurettin Sahiner
Summary: In this research, a Metal-Organic Framework (MOF) based on Trimesic Acid and Co(II) was developed as a sensing material for ammonia detection. The activated MOF showed a low detection limit of 60 ppm and exhibited excellent stability and reversibility in the cyclic test. The color detection of MOF upon exposure to NH3 was easily recoverable by interaction with acid.
IEEE SENSORS JOURNAL
(2022)
Article
Chemistry, Inorganic & Nuclear
Sahin Demirci, Yildiz Yildrim, Nurettin Sahiner
Summary: Zeolitic imidazolate framework particles were synthesized in water at room temperature using 2-methylimidazole as the organic linker. The colors of prepared ZIF particles varied depending on the metal ions used, and their antibacterial activities also showed differences.
INORGANICA CHIMICA ACTA
(2022)
Review
Peripheral Vascular Disease
Bruna Visniauskas, Isabella Kilanowski-Doroh, Benard O. Ogola, Alexandra B. Mcnally, Alec C. Horton, Ariane Imulinde Sugi, Sarah H. Lindsey
Summary: Cardiovascular disease (CVD) is the leading cause of death globally. Premenopausal women have a lower incidence of hypertension and other cardiovascular events than men, possibly due to the protective effects of 17-beta-estradiol (E2). This review summarizes the estrogen-mediated mechanisms underlying sex differences in hypertension and CVD and identifies knowledge gaps in this field.
JOURNAL OF HUMAN HYPERTENSION
(2023)
Article
Chemistry, Physical
Sahin Demirci, Selin S. Suner, Mustafa Yildiz, Nurettin Sahiner
Summary: In this study, polymeric ionic liquid (PIL) forms of polyethyleneimine (PEI) microgels were prepared and used as metal-free catalysts for hydrogen production from sodium borohydride (NaBH4) solution in methanol. The PEI-based PIL microgels exhibited excellent catalytic performances and regenerability, enabling hydrogen production at various temperatures and easy recovery of catalytic activities through regeneration treatments.
JOURNAL OF MOLECULAR LIQUIDS
(2022)
Article
Chemistry, Physical
Olgun Guven, Sahin Demirci, S. Duygu Sutekin, Betul Ari, Nurettin Sahiner
Summary: Hydrogels with reactive thiourea functional groups were prepared by radiation-induced crosslinking, and metal nanoparticles were prepared within the hydrogel matrix. The hydrogel composites were used as catalysts in a reduction reaction, and the factors affecting their catalytic activity were investigated.
RADIATION PHYSICS AND CHEMISTRY
(2022)
Article
Polymer Science
Mehtap Sahiner, Sahin Demirci, Nurettin Sahiner
Summary: Halloysite nanotubes (HNT) were coated with dopamine to form polydopamine-coated HNTs (PDOPA@HNT) with reduced surface area and pore size. Increasing the number of coatings decreased the surface area. The PDOPA@HNTs showed enhanced antioxidant properties and enzyme inhibition capabilities.
Article
Chemistry, Physical
Sahin Demirci, Nurettin Sahiner
Summary: In this study, Dex cryogels were prepared and used for immobilizing alpha-Glu enzyme via entrapment and covalent linking techniques. Entrapment of alpha-Glu enzyme resulted in a significant activity loss, while covalent linking maintained high activity and allowed for multiple usages and storage. Additionally, a Dex-Co metal nanoparticle composite was prepared to immobilize alpha-Glu enzyme for dual catalytic performance.
Article
Environmental Sciences
Sema Bagdat, Feyzullah Tokay, Sahin Demirci, Selehattin Yilmaz, Nurettin Sahiner
Summary: Super porous polyethyleneimine (PEI) cryogels were used as adsorbents to remove Cd(II), Co(II), Cr(III), Ni(II), Pb(II), and Zn(II) from contaminated waters. The optimum pH value and contact time for removing the analytes were determined as 4.0 and 90 min, respectively. The adsorption capacities of the sorbent ranged from 19.88 to 24.39 mg/g for target metal ion solutions with a concentration of 50 mg/L. The adsorption kinetics followed the pseudo-second-order model, and the adsorption isotherms followed the Langmuir isotherm model. The PEI cryogels showed selectivity and tolerance to high concentrations of different ions and successfully removed the target analytes from industrial wastewater samples with removal rates ranging from 80.35% to 99.89%.
JOURNAL OF ENVIRONMENTAL MANAGEMENT
(2023)
Article
Chemistry, Physical
Sahin Demirci, S. Duygu Sutekin, Olgun Guven, Nurettin Sahiner
Summary: Poly(2-aminoethyl methacrylate) (p(AEM)) microgels were synthesized and used for metal nanoparticle preparation. These microgels were then incorporated into p(AEM) based poly ionic liquid (PIL) microgels, which served as catalysts for hydrogen production from sodium borohydride (NaBH4) reactions. The catalytic activity and regeneration ability of the microgels were analyzed, showing promising results.
INTERNATIONAL JOURNAL OF HYDROGEN ENERGY
(2023)
Article
Chemistry, Analytical
Betul Ari, Mehtap Sahiner, Selin Sagbas Suner, Sahin Demirci, Nurettin Sahiner
Summary: Super-macroporous cryogel made from pullulan, a natural polysaccharide, was synthesized using a cryo-crosslinking technique. The hydrolytic degradation of the cryogel in different buffer solutions was evaluated, with faster degradation observed in pH 9.0 buffer solution. The cryogel demonstrated controlled drug release potential, with ciprofloxacin loaded and released in a physiological condition with high antimicrobial efficacy and low toxicity on fibroblast cells.
Article
Astronomy & Astrophysics
S. Demirci, T. Lappi, S. Schlichting
Summary: By calculating cross sections with fluctuating color charges Gaussian hot spots, we find that the existence of gluonic hot spots inside the proton affects the production cross sections, which are sensitive to the size of the target, the structure of the probe, and the transverse momentum transfer (t).
Article
Materials Science, Multidisciplinary
Sahin Demirci, Nurettin Sahiner
Summary: Graphitic carbon nitride and heteroatom-doped carbon nitride catalysts show higher catalytic performance in the dehydrogenation reaction of sodium borohydride in methanol compared to bare carbon nitride catalyst. The hydrogen generation rate and activation energy are improved for the reactions catalyzed by heteroatom-doped catalysts. Additionally, the heteroatom-doped catalysts exhibit good stability and activity in the reuse studies.
C-JOURNAL OF CARBON RESEARCH
(2022)
Article
Pharmacology & Pharmacy
Xueliang Xiu, Shichao Ma, Zhiyong Li, Zhipeng Li, Xuemei Li, Yangtao Ruan, Dezhao Li, Jianwei Wang, Fengsen Ma
Summary: Liposomes are promising delivery vehicles for drugs and vaccines. The use of microfluidic chips for liposome preparation is an effective method. However, traditional liposome preparation technologies hinder their industrial production and clinical application. This study presents a novel three-dimensional integrated microfluidic device for continuous liposome preparation and purification, which shows potential for industrial production of nano-pharmaceutical applications.
JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY
(2024)