Amino acids and the regulation of oxidative stress and immune function in dairy cattle

Enhanced supply of methionine or arginine alters mechanistic target of rapamycin signaling proteins, messenger RNA, and microRNA abundance in heat-stressed bovine mammary epithelial cells in vitro

(2019) A.A.K. Salama et al.   JOURNAL OF DAIRY SCIENCE

Phosphorylation of AKT serine/threonine kinase and abundance of milk protein synthesis gene networks in mammary tissue in response to supply of methionine in periparturient Holstein cows

(2019) Y.F. Ma et al.   JOURNAL OF DAIRY SCIENCE

Methionine supply during the periparturient period enhances insulin signaling, amino acid transporters, and mechanistic target of rapamycin pathway proteins in adipose tissue of Holstein cows

(2019) Y. Liang et al.   JOURNAL OF DAIRY SCIENCE

Immune system stimulation increases the plasma cysteine flux and whole-body glutathione synthesis rate in starter pigs1

(2019) Anoosh Rakhshandeh et al.   JOURNAL OF ANIMAL SCIENCE

Glutathione metabolism and nuclear factor erythroid 2-like 2 (NFE2L2)-related proteins in adipose tissue are altered by supply of ethyl-cellulose rumen-protected methionine in peripartal Holstein cows

(2019) Y. Liang et al.   JOURNAL OF DAIRY SCIENCE

Inflammation and oxidative stress transcription profiles due to in vitro supply of methionine with or without choline in unstimulated blood polymorphonuclear leukocytes from lactating Holstein cows

(2019) V. Lopreiato et al.   JOURNAL OF DAIRY SCIENCE

Hepatic 1-carbon metabolism enzyme activity, intermediate metabolites, and growth in neonatal Holstein dairy calves are altered by maternal supply of methionine during late pregnancy

(2019) A.S. Alharthi et al.   JOURNAL OF DAIRY SCIENCE

Short communication: Supply of methionine during late pregnancy enhances whole-blood innate immune response of Holstein calves partly through changes in mRNA abundance in polymorphonuclear leukocytes

(2019) A.S. Alharthi et al.   JOURNAL OF DAIRY SCIENCE

Serine prevented high-fat diet-induced oxidative stress by activating AMPK and epigenetically modulating the expression of glutathione synthesis-related genes

(2018) Xihong Zhou et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

The role of ASCT2 in cancer: A review

(2018) Yang Liu et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Rapid Communication: Jugular infusion of arginine has a positive effect on antioxidant mechanisms in lactating dairy cows challenged intravenously with lipopolysaccharide

(2018) F F Zhao et al.   JOURNAL OF ANIMAL SCIENCE

Methionine supply alters mammary gland antioxidant gene networks via phosphorylation of nuclear factor erythroid 2-like 2 (NFE2L2) protein in dairy cows during the periparturient period

(2018) L. Han et al.   JOURNAL OF DAIRY SCIENCE

Maternal supply of methionine during late pregnancy is associated with changes in immune function and abundance of microRNA and mRNA in Holstein calf polymorphonuclear leukocytes

(2018) C.B. Jacometo et al.   JOURNAL OF DAIRY SCIENCE

Ethyl-cellulose rumen-protected methionine alleviates inflammation and oxidative stress and improves neutrophil function during the periparturient period and early lactation in Holstein dairy cows

(2018) F. Batistel et al.   JOURNAL OF DAIRY SCIENCE

Varying the ratio of Lys:Met while maintaining the ratios of Thr:Phe, Lys:Thr, Lys:His, and Lys:Val alters mammary cellular metabolites, mammalian target of rapamycin signaling, and gene transcription

(2018) X. Dong et al.   JOURNAL OF DAIRY SCIENCE

Jugular arginine infusion relieves lipopolysaccharide-triggered inflammatory stress and improves immunity status of lactating dairy cows

(2018) F.F. Zhao et al.   JOURNAL OF DAIRY SCIENCE

Glycine Increases Insulin Sensitivity and Glutathione Biosynthesis and Protects against Oxidative Stress in a Model of Sucrose-Induced Insulin Resistance

(2018) Mohammed El-Hafidi et al.   Oxidative Medicine and Cellular Longevity

Cystathionine β-Synthase in Physiology and Cancer

(2018) Haoran Zhu et al.   Biomed Research International

Nutrients Mediate Intestinal Bacteria–Mucosal Immune Crosstalk

(2018) Ning Ma et al.   Frontiers in Immunology

Polyamines: Bio-Molecules with Diverse Functions in Plant and Human Health and Disease

(2018) Avtar K. Handa et al.   Frontiers in Chemistry

Effects of chronic heat stress on lactational performance and the transcriptomic profile of blood cells in lactating dairy goats

(2018) Alexandra Contreras-Jodar et al.   JOURNAL OF DAIRY RESEARCH

Methionine and choline supply during the peripartal period alter polymorphonuclear leukocyte immune response and immunometabolic gene expression in Holstein cows

(2018) Z. Zhou et al.   JOURNAL OF DAIRY SCIENCE

Nutrient-sensing kinase signaling in bovine immune cells is altered during the postpartum nutrient deficit: A possible role in transition cow inflammatory response

(2018) S. Mann et al.   JOURNAL OF DAIRY SCIENCE

Adaptations of hepatic lipid metabolism and mitochondria in dairy cows with mild fatty liver

(2018) Xiliang Du et al.   JOURNAL OF DAIRY SCIENCE

Role of Histamine in Modulating the Immune Response and Inflammation

(2018) Anna Cláudia Calvielli Castelo Branco et al.   MEDIATORS OF INFLAMMATION

Branched Chain Amino Acids

(2018) Michael Neinast et al.   Annual Review of Physiology

The degree of postpartum metabolic challenge in dairy cows is associated with peripheral blood mononuclear cell transcriptome changes of the innate immune system

(2018) Sabine Mann et al.   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY

Topotecan induces apoptosis via ASCT2 mediated oxidative stress in gastric cancer

(2018) Lai Wang et al.   PHYTOMEDICINE

Glutamate attenuates lipopolysaccharide-induced oxidative damage and mRNA expression changes of tight junction and defensin proteins, inflammatory and apoptosis response signaling molecules in the intestine of fish

(2017) Jun Jiang et al.   FISH & SHELLFISH IMMUNOLOGY

MenTORing Immunity: mTOR Signaling in the Development and Function of Tissue-Resident Immune Cells

(2017) Russell G. Jones et al.   IMMUNITY

Supplementation with rumen-protected methionine or choline during the transition period influences whole-blood immune response in periparturient dairy cows

(2017) M. Vailati-Riboni et al.   JOURNAL OF DAIRY SCIENCE

Ethyl-cellulose rumen-protected methionine enhances performance during the periparturient period and early lactation in Holstein dairy cows

(2017) F. Batistel et al.   JOURNAL OF DAIRY SCIENCE

Supplemental methionine, choline, or taurine alter in vitro gene network expression of polymorphonuclear leukocytes from neonatal Holstein calves

(2017) M.K. Abdelmegeid et al.   JOURNAL OF DAIRY SCIENCE

Serine alleviates oxidative stress via supporting glutathione synthesis and methionine cycle in mice

(2017) Xihong Zhou et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Choline and methionine differentially alter methyl carbon metabolism in bovine neonatal hepatocytes

(2017) Tawny L. Chandler et al.   PLoS One

Effects of dietary threonine and immune stress on growth performance, carcass trait, serum immune parameters, and intestinal muc2 and NF-κb gene expression in Pekin ducks from hatch to 21 days

(2017) Y Bi et al.   POULTRY SCIENCE

SAMTOR is anS-adenosylmethionine sensor for the mTORC1 pathway

(2017) Xin Gu et al.   SCIENCE

Dietary leucine improves flesh quality and alters mRNA expressions of Nrf2-mediated antioxidant enzymes in the muscle of grass carp ( Ctenopharyngodon idella )

(2016) Yu-Ping Deng et al.   AQUACULTURE

Whole-body and splanchnic amino acid metabolism in sheep during an acute endotoxin challenge

(2016) C. J. McNeil et al.   BRITISH JOURNAL OF NUTRITION

Effect of threonine deficiency on intestinal integrity and immune response to feed withdrawal combined with coccidial vaccine challenge in broiler chicks

(2016) Qian Zhang et al.   BRITISH JOURNAL OF NUTRITION

The CASTOR Proteins Are Arginine Sensors for the mTORC1 Pathway

(2016) Lynne Chantranupong et al.   CELL

Threonine modulates immune response, antioxidant status and gene expressions of antioxidant enzymes and antioxidant-immune-cytokine-related signaling molecules in juvenile blunt snout bream ( Megalobrama amblycephala )

(2016) Habte-Michael Habte-Tsion et al.   FISH & SHELLFISH IMMUNOLOGY

Changes in integrity of the gill during histidine deficiency or excess due to depression of cellular anti-oxidative ability, induction of apoptosis, inflammation and impair of cell-cell tight junctions related to Nrf2, TOR and NF-κB signaling in fish

(2016) Wei-Dan Jiang et al.   FISH & SHELLFISH IMMUNOLOGY

Effect of dietary threonine on laying performance and intestinal immunity of laying hens fed low-crude-protein diets during the peak production period

(2016) M. M. M. Azzam et al.   JOURNAL OF ANIMAL PHYSIOLOGY AND ANIMAL NUTRITION

Maternal rumen-protected methionine supplementation and its effect on blood and liver biomarkers of energy metabolism, inflammation, and oxidative stress in neonatal Holstein calves

(2016) C.B. Jacometo et al.   JOURNAL OF DAIRY SCIENCE

Circulating amino acids in blood plasma during the peripartal period in dairy cows with different liver functionality index

(2016) Z. Zhou et al.   JOURNAL OF DAIRY SCIENCE

Rumen-protected methionine compared with rumen-protected choline improves immunometabolic status in dairy cows during the peripartal period

(2016) Z. Zhou et al.   JOURNAL OF DAIRY SCIENCE

Better postpartal performance in dairy cows supplemented with rumen-protected methionine compared with choline during the peripartal period

(2016) Z. Zhou et al.   JOURNAL OF DAIRY SCIENCE

Hepatic Activity and Transcription of Betaine-Homocysteine Methyltransferase, Methionine Synthase, and Cystathionine Synthase in Periparturient Dairy Cows Are Altered to Different Extents by Supply of Methionine and Choline

(2016) Zheng Zhou et al.   JOURNAL OF NUTRITION

Arginine Relieves the Inflammatory Response and Enhances the Casein Expression in Bovine Mammary Epithelial Cells Induced by Lipopolysaccharide

(2016) Tianyou Wu et al.   MEDIATORS OF INFLAMMATION

Methionine and Choline Supply during the Periparturient Period Alter Plasma Amino Acid and One-Carbon Metabolism Profiles to Various Extents: Potential Role in Hepatic Metabolism and Antioxidant Status

(2016) Zheng Zhou et al.   Nutrients

Regulation of Nutritional Metabolism in Transition Dairy Cows: Energy Homeostasis and Health in Response to Post-Ruminal Choline and Methionine

(2016) Feifei Sun et al.   PLoS One

Dietary supplementation with l-glutamate and l-aspartate alleviates oxidative stress in weaned piglets challenged with hydrogen peroxide

(2015) Jielin Duan et al.   AMINO ACIDS

Effects of supplementation of rumen-protected choline on growth performance, meat quality and gene expression inlongissimus dorsimuscle of lambs

(2015) Huawei Li et al.   ARCHIVES OF ANIMAL NUTRITION

Branched-chain Amino Acids are Beneficial to Maintain Growth Performance and Intestinal Immune-related Function in Weaned Piglets Fed Protein Restricted Diet

(2015) M. Ren et al.   ASIAN-AUSTRALASIAN JOURNAL OF ANIMAL SCIENCES

Mucins: A biologically relevant glycan barrier in mucosal protection

(2015) Anthony P. Corfield   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Responses in whole-body amino acid kinetics to an acute, sub-clinical endotoxin challenge in lambs

(2015) S. O. Hoskin et al.   BRITISH JOURNAL OF NUTRITION

In vitro and in vivo protective effect of arginine against lipopolysaccharide induced inflammatory response in the intestine of juvenile Jian carp (Cyprinus carpio var. Jian)

(2015) Jun Jiang et al.   FISH & SHELLFISH IMMUNOLOGY

A deficiency or an excess of dietary threonine level affects weight gain, enzyme activity, immune response and immune-related gene expression in juvenile blunt snout bream (Megalobrama amblycephala)

(2015) Habte-Michael Habte-Tsion et al.   FISH & SHELLFISH IMMUNOLOGY

Invited review: Inflammation during the transition to lactation: New adventures with an old flame

(2015) B.J. Bradford et al.   JOURNAL OF DAIRY SCIENCE

l-Cysteine metabolism and its nutritional implications

(2015) Jie Yin et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Nitric oxide synthase in innate and adaptive immunity: an update

(2015) Christian Bogdan   TRENDS IN IMMUNOLOGY

Insight into the role of mTOR and metabolism in T cells reveals new potential approaches to preventing graft rejection

(2014) Ying-Chun Lo et al.   Current Opinion in Organ Transplantation

The impaired intestinal mucosal immune system by valine deficiency for young grass carp (Ctenopharyngodon idella) is associated with decreasing immune status and regulating tight junction proteins transcript abundance in the intestine

(2014) Jian-Bo Luo et al.   FISH & SHELLFISH IMMUNOLOGY

Smartamine M and MetaSmart supplementation during the peripartal period alter hepatic expression of gene networks in 1-carbon metabolism, inflammation, oxidative stress, and the growth hormone–insulin-like growth factor 1 axis pathways

(2014) J.S. Osorio et al.   JOURNAL OF DAIRY SCIENCE

Biomarkers of inflammation, metabolism, and oxidative stress in blood, liver, and milk reveal a better immunometabolic status in peripartal cows supplemented with Smartamine M or MetaSmart

(2014) J.S. Osorio et al.   JOURNAL OF DAIRY SCIENCE

Amino Acids and Immune Response: A Role for Cysteine, Glutamine, Phenylalanine, Tryptophan and Arginine in T-cell Function and Cancer?

(2014) Angelos K. Sikalidis   PATHOLOGY & ONCOLOGY RESEARCH

Ratio of lysine to methionine alters expression of genes involved in milk protein transcription and translation and mTOR phosphorylation in bovine mammary cells

(2014) Xuemei Nan et al.   PHYSIOLOGICAL GENOMICS

Effects of Arginine Concentration on the In Vitro Expression of Casein and mTOR Pathway Related Genes in Mammary Epithelial Cells from Dairy Cattle

(2014) Mengzhi Wang et al.   PLoS One

Therapeutic Effects of Glutamic Acid in Piglets Challenged with Deoxynivalenol

(2014) Miaomiao Wu et al.   PLoS One

Impairment of innate immune responses in cirrhotic patients and treatment by branched-chain amino acids

(2014) Ikuo Nakamura   WORLD JOURNAL OF GASTROENTEROLOGY

Glycine metabolism in animals and humans: implications for nutrition and health

(2013) Weiwei Wang et al.   AMINO ACIDS

Precursors for liver gluconeogenesis in periparturient dairy cows

(2013) M. Larsen et al.   Animal

Dietary l-arginine supplementation attenuates lipopolysaccharide-induced inflammatory response in broiler chickens

(2013) Jianzhuang Tan et al.   BRITISH JOURNAL OF NUTRITION

Influence of different histidine sources and zinc supplementation of broiler diets on dipeptide content and antioxidant status of blood and meat

(2013) W. Kopeć et al.   BRITISH POULTRY SCIENCE

Glutathione defense mechanism in liver injury: Insights from animal models

(2013) Y. Chen et al.   FOOD AND CHEMICAL TOXICOLOGY

Immune system stimulation increases the optimal dietary methionine to methionine plus cysteine ratio in growing pigs1

(2013) N. Litvak et al.   JOURNAL OF ANIMAL SCIENCE

Supplemental Smartamine M or MetaSmart during the transition period benefits postpartal cow performance and blood neutrophil function

(2013) J.S. Osorio et al.   JOURNAL OF DAIRY SCIENCE

Use of the Liver Activity Index and Other Metabolic Variables in the Assessment of Metabolic Health in Dairy Herds

(2013) Giuseppe Bertoni et al.   VETERINARY CLINICS OF NORTH AMERICA-FOOD ANIMAL PRACTICE

Nutritional management of the transition cow in the 21st century ? a paradigm shift in thinking

(2013) J. R. Roche et al.   Animal Production Science

Functional welfare ? using biochemical and molecular technologies to understand better the welfare state of peripartal dairy cattle

(2013) J. J. Loor et al.   Animal Production Science

Systems Physiology in Dairy Cattle: Nutritional Genomics and Beyond

(2013) Juan J. Loor et al.   Annual Review of Animal Biosciences

The immune modifying effects of amino acids on gut-associated lymphoid tissue

(2013) Megan R Ruth et al.   Journal of Animal Science and Biotechnology

Nutrition, immune function and health of dairy cattle

(2012) K. L. Ingvartsen et al.   Animal

Regulation of Immune Responses by mTOR

(2012) Jonathan D. Powell et al.   Annual Review of Immunology

Effect of l-arginine on intestinal mucosal immune barrier function in weaned pigs after Escherichia coli LPS challenge

(2012) HL Zhu et al.   Innate Immunity

Effect of parenteral administration of glutamine on autophagy of liver cell and immune responses in weaned calves

(2012) Z. Y. Hu et al.   JOURNAL OF ANIMAL PHYSIOLOGY AND ANIMAL NUTRITION

Zn2+ and l-isoleucine induce the expressions of porcine β-defensins in IPEC-J2 cells

(2012) Xiangbing Mao et al.   MOLECULAR BIOLOGY REPORTS

Glutamine and Leucine Provide Enhanced Protective Immunity Against Mucosal Infection with Herpes Simplex Virus Type 1

(2012) Erdenebileg Uyangaa et al.   Immune Network

Induction of β-defensins by l-isoleucine as novel immunotherapy in experimental murine tuberculosis

(2011) C. E. Rivas-Santiago et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Effects of supplementation with 2-hydroxy-4-(methylthio)-butanoic acid isopropyl ester on splanchnic amino acid metabolism and essential amino acid mobilization in postpartum transition Holstein cows

(2011) K.F. Dalbach et al.   JOURNAL OF DAIRY SCIENCE

Improvements of immune status, intestinal integrity and gain performance in the early-weaned calves parenterally supplemented with l-alanyl-l-glutamine dipeptide

(2011) Yuxiang Zhou et al.   VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY

Control of immune response by amino acid metabolism

(2010) Ursula Grohmann et al.   IMMUNOLOGICAL REVIEWS

Overview of the immune response

(2010) David D. Chaplin   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Innate immunity

(2009) Stuart E. Turvey et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Effects of providing two forms of supplemental methionine to periparturient Holstein dairy cows on feed intake and lactational performance

(2009) R.S. Ordway et al.   JOURNAL OF DAIRY SCIENCE

Intestinal mucin dynamics: Response of broiler chicks and White Pekin ducklings to dietary threonine

(2009) N. L. Horn et al.   POULTRY SCIENCE

Arginine metabolism and nutrition in growth, health and disease

(2008) Guoyao Wu et al.   AMINO ACIDS

Dietary Histidine Ameliorates Murine Colitis by Inhibition of Proinflammatory Cytokine Production From Macrophages

(2008) Ayatoshi Andou et al.   GASTROENTEROLOGY

Optimal Concentrations of Lysine, Methionine, and Threonine in Milk Replacers for Calves Less than Five Weeks of Age

(2008) T.M. Hill et al.   JOURNAL OF DAIRY SCIENCE

Effects of Inflammatory Conditions on Liver Activity in Puerperium Period and Consequences for Performance in Dairy Cows

(2008) G. Bertoni et al.   JOURNAL OF DAIRY SCIENCE