Article
Multidisciplinary Sciences
Kay Boulton, Peter W. Wilson, Valerie R. Bishop, Jonathan H. Perez, Toby Wilkinson, Kris Hogan, Natalie Z. M. Homer, Christelle Robert, Jacqueline Smith, Simone L. Meddle, Ian C. Dunn, Kellie Watson
Summary: The study found that the diet and egg treatment of Japanese quail parents significantly affect the growth, reproductive capacity, and stress response of the first generation. Additionally, while maternal stress may have an impact on offspring, enhanced methyl diets appear to have positive effects on bird reproduction, growth, and stress function.
SCIENTIFIC REPORTS
(2021)
Article
Nutrition & Dietetics
Heleen Van Puyvelde, Nikos Papadimitriou, Joanna Clasen, David Muller, Carine Biessy, Pietro Ferrari, Jytte Halkjaer, Kim Overvad, Anne Tjonneland, Renee T. Fortner, Verena Katzke, Matthias B. Schulze, Paolo Chiodini, Giovanna Masala, Valeria Pala, Carlotta Sacerdote, Rosario Tumino, Marije F. Bakker, Antonio Agudo, Eva Ardanaz, Maria Dolores Chirlaque Lopez, Maria-Jose Sanchez, Ulrika Ericson, Bjorn Gylling, Therese Karlsson, Jonas Manjer, Julie A. Schmidt, Genevieve Nicolas, Corinne Casagrande, Elisabete Weiderpass, Alicia K. Heath, Lode Godderis, Koen Van Herck, Dirk De Bacquer, Marc J. Gunter, Inge Huybrechts
Summary: The study did not find strong evidence for an association between methyl-group donors involved in one-carbon metabolism and breast cancer risk. However, there was a potential U-shaped trend suggested for dietary folate intake and breast cancer risk. Further research is needed to clarify this association.
Article
Nutrition & Dietetics
Julie M. Petersen, Rashida S. Smith-Webb, Gary M. Shaw, Suzan L. Carmichael, Tania A. Desrosiers, Eirini Nestoridi, Anne Marie Darling, Samantha E. Parker, Maria D. Politis, Mahsa M. Yazdy, Martha M. Werler
Summary: The study showed that concurrent intake of multiple micronutrients can more effectively reduce the risk of neural tube defects, especially with simultaneous higher intakes of vitamin B6, vitamin B12, choline, betaine, and methionine.
AMERICAN JOURNAL OF CLINICAL NUTRITION
(2023)
Article
Biochemistry & Molecular Biology
Annie S. P. Yang, Youri M. van Waardenburg, Marga van de Vegte-Bolmer, Geert-Jan A. van Gemert, Wouter Graumans, Johannes H. W. de Wilt, Robert W. Sauerwein
Summary: The development of Plasmodium falciparum in hepatocytes is strongly influenced by the metabolic status of hepatocyte subtypes, with a selective preference for a minority of hepatocytes. Schizont growth is significantly enhanced by the uptake of glutamine synthetase (hGS), showcasing a novel import system. These findings underscore the importance of understanding detailed hepatocyte host-Plasmodium falciparum interactions and may provide new pathways for intervention strategies.
Article
Nutrition & Dietetics
Ting Chen, Na Tao, Sheng Yang, Dafang Cao, Xun Zhao, Donghong Wang, Jun Liu
Summary: The study found that higher dietary intake of specific one-carbon metabolism-related nutrients, such as betaine, choline, methionine, folate, and vitamin B-6, is associated with lower prevalence of fluorosis.
FRONTIERS IN NUTRITION
(2021)
Correction
Multidisciplinary Sciences
T. L. Chandler, S. J. Erb, William A. Myers, Pragney Deme, Norman J. Haughey, J. W. McFadden, H. M. White
Summary: The paper has been amended and the revised version can be accessed through a link at the top of the paper.
SCIENTIFIC REPORTS
(2021)
Article
Biology
Mahmoud Alagawany, Shaaban S. Elnesr, Mayada R. Farag, Karima El-Naggar, Ayman E. Taha, Asmaa F. Khafaga, Mahmoud Madkour, Heba M. Salem, Amira M. El-Tahan, Mohamed T. El-Saadony, Mohamed E. Abd El-Hack
Summary: Betaine functions as an osmolyte and methyl donor, helping animals cope with osmotic stress. Despite inconsistent research results, some key findings, such as improved growth performance and heat stress resistance, are repeatedly discovered. Therefore, the widespread use of betaine and methionine as feed supplements in poultry diets can enhance poultry production performance and meat quality.
JOURNAL OF THERMAL BIOLOGY
(2022)
Article
Nutrition & Dietetics
O. Chandani Dinesh, Thillayampalam Kankayaliyan, Meike Rademacher, Christopher Tomlinson, Robert F. Bertolo, Janet A. Brunton
Summary: Research found that supplemental GAA or creatine can reduce the utilization of arginine and methionine in piglets, and excess methionine is necessary for the conversion of GAA to creatine.
JOURNAL OF NUTRITION
(2021)
Article
Agronomy
Narda J. Trivino, Alejandro Rodriguez-Sanchez, Timothy Filley, James J. Camberato, Micaela Colley, Phillip Simon, Lori Hoagland
Summary: By studying carrot genotypes, it was found that different genotypes have varying abilities to decompose organic materials in the soil, and can stimulate the increase of specific bacterial communities, thereby promoting organic matter decomposition. This finding is helpful for selectively breeding carrot varieties with the ability to promote soil organic matter decomposition.
Article
Environmental Sciences
Jie Xu, Xin-Ling Wang, Han-Fang Zeng, Zhao-Yu Han
Summary: In this study, the regulatory effect and mechanism of methionine (Met) in alleviating heat stress-induced ferroptosis in bovine mammary epithelial cells were investigated. The results showed that Met increased the expression levels of GPX4, SLC7A11, and FTH1 by activating Nrf2, resulting in a decrease in LIP and lipid ROS levels, thus alleviating heat stress-induced ferroptosis. These findings highlight the significant role of Met in mitigating bovine mammary gland injury caused by heat stress.
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
(2023)
Article
Nutrition & Dietetics
Li Ding, Qinglin Yang, Zhongming Sun, Lu Liu, Zeyu Meng, Xun Zhao, Na Tao, Jun Liu
Summary: This study aimed to investigate the association between habitual dietary intake of one-carbon metabolism nutrients and hyperglycemia in a fluorosis area in China. The results showed that higher dietary intake of vitamin B-6, total choline, methyl-donor index, free choline, glycerol phosphorylcholine, and phosphocholine were associated with a lower incidence of hyperglycemia. Moreover, the associations were modified by the presence or absence of fluorosis.
FRONTIERS IN NUTRITION
(2022)
Article
Biochemistry & Molecular Biology
Eliab Estrada-Cortes, William Ortiz, Maria B. Rabaglino, Jeremy Block, Owen Rae, Elizabeth A. Jannaman, Yao Xiao, Peter J. Hansen
Summary: Provision of the methyl-donor choline to preimplantation embryos can alter their developmental program to increase gestation length, birth weight, and weaning weight, and cause postnatal changes in muscle DNA methylation associated with genes related to anabolic processes and cellular growth, highlighting the importance of embryo nutritional status for health and well-being after birth.
Article
Nutrition & Dietetics
Anthea Van Parys, Maria Sandvik Braekke, Therese Karlsson, Kathrine J. Vinknes, Grethe S. Tell, Teresa R. Haugsgjerd, Per Magne Ueland, Jannike Oyen, Jutta Dierkes, Ottar Nygard, Vegard Lysne
Summary: This study investigated the dietary intake of choline and its association with one-carbon metabolites and lipids in community-dwelling adults in Norway. The findings suggest that choline intake is correlated with the concentration of most metabolites involved in one-carbon and lipid metabolism.
JOURNAL OF NUTRITION
(2022)
Article
Nutrition & Dietetics
Aura (alex) P. Loinard-Gonzalez, Olga Malysheva, Kevin C. Klatt, Marie A. Caudill
Summary: This study investigated the impact of genetic variants in one-carbon metabolism genes on DHA status, and found that genotype may influence maternal and fetal DHA levels, highlighting the importance of considering genetic variants in one-carbon metabolic genes during pregnancy.
Article
Biochemistry & Molecular Biology
Eduardo Sanches, Yohan van de Looij, Dini Ho, Laura Modernell, Analina da Silva, Stephane Sizonenko
Summary: Combining early oral administration of lactoferrin with whole body hypothermia can enhance neuroprotection in neonatal hypoxic-ischemic encephalopathy, preventing lactate accumulation, reducing inflammation, and mitigating brain damage.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)