Bone-Targeted Extracellular Vesicles from Mesenchymal Stem Cells for Osteoporosis Therapy

Exosomes Secreted by Young Mesenchymal Stem Cells Promote New Bone Formation During Distraction Osteogenesis in Older Rats

(2020) Yachao Jia et al.   CALCIFIED TISSUE INTERNATIONAL

Treating osteoporosis to prevent fractures: current concepts and future developments

(2019) Mattias Lorentzon   JOURNAL OF INTERNAL MEDICINE

Extracellular vesicles from human umbilical cord blood ameliorate bone loss in senile osteoporotic mice

(2019) Yin Hu et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Long-Term Drug Therapy and Drug Discontinuations and Holidays for Osteoporosis Fracture Prevention

(2019) Howard A. Fink et al.   ANNALS OF INTERNAL MEDICINE

On resin click-chemistry-mediated synthesis of novel enkephalin analogues with potent anti-nociceptive activity

(2019) Azzurra Stefanucci et al.   Scientific Reports

Advancement of Peptide Nanobiotechnology via Emerging Microfluidic Technology

(2019) Chan et al.   Micromachines

Large-scale generation of functional mRNA-encapsulating exosomes via cellular nanoporation

(2019) Zhaogang Yang et al.   Nature Biomedical Engineering

NRP-1 targeted and cargo-loaded exosomes facilitate simultaneous imaging and therapy of glioma in vitro and in vivo

(2018) Gang Jia et al.   BIOMATERIALS

Longitudinal Effects of Teriparatide or Zoledronic Acid on Bone Modeling- and Remodeling-Based Formation in the SHOTZ Study

(2018) David W Dempster et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Technical challenges of working with extracellular vesicles

(2018) Marcel I. Ramirez et al.   Nanoscale

Romosozumab versus Alendronate and Fracture Risk in Women with Osteoporosis

(2018)   NEW ENGLAND JOURNAL OF MEDICINE

A Prospective, Controlled, Multicenter Study to Evaluate the Clinical Outcome of Implant Treatment in Women with Osteoporosis/Osteopenia: 5-Year Results

(2018) A. Temmerman et al.   JOURNAL OF DENTAL RESEARCH

Synthesis of next generation dual-responsive cross-linked nanoparticles and their application to anti-cancer drug delivery

(2018) Christina Schwarzenböck et al.   Nanoscale

The Activity of Peptides of the Calcitonin Family in Bone

(2018) Dorit Naot et al.   PHYSIOLOGICAL REVIEWS

C-Terminal Residue of Ultrashort Peptides Impacts on Molecular Self-Assembly, Hydrogelation, and Interaction with Small-Molecule Drugs

(2018) Kiat Hwa Chan et al.   Scientific Reports

Drug-Related Adverse Events of Osteoporosis Therapy

(2017) Moin Khan et al.   ENDOCRINOLOGY AND METABOLISM CLINICS OF NORTH AMERICA

Molecular Recognition-Based DNA Nanoassemblies on the Surfaces of Nanosized Exosomes

(2017) Shuo Wan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Mesenchymal stem cells release exosomes that transfer miRNAs to endothelial cells and promote angiogenesis

(2017) Min Gong et al.   Oncotarget

Exosomes derived from miR-140-5p-overexpressing human synovial mesenchymal stem cells enhance cartilage tissue regeneration and prevent osteoarthritis of the knee in a rat model

(2017) Shi-Cong Tao et al.   Theranostics

Extracellular vesicles for drug delivery

(2016) Pieter Vader et al.   ADVANCED DRUG DELIVERY REVIEWS

Delivery of Therapeutic Proteins via Extracellular Vesicles: Review and Potential Treatments for Parkinson’s Disease, Glioma, and Schwannoma

(2016) Justin Hall et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Alkaloids and Isoprenoids Modification by Copper(I)-Catalyzed Huisgen 1,3-Dipolar Cycloaddition (Click Chemistry): Toward New Functions and Molecular Architectures

(2016) Karol Kacprzak et al.   CHEMICAL REVIEWS

Influence of Skeletal and Local Bone Density on Dental Implant Stability in Patients with Osteoporosis

(2016) Joe Merheb et al.   Clinical Implant Dentistry and Related Research

Exosomes Secreted by Human-Induced Pluripotent Stem Cell-Derived Mesenchymal Stem Cells Repair Critical-Sized Bone Defects through Enhanced Angiogenesis and Osteogenesis in Osteoporotic Rats

(2016) Xin Qi et al.   International Journal of Biological Sciences

Recapitulating the Size and Cargo of Tumor Exosomes in a Tissue-Engineered Model

(2016) Aranzazu Villasante et al.   Theranostics

Hijacking the Cellular Mail: Exosome Mediated Differentiation of Mesenchymal Stem Cells

(2016) Raghuvaran Narayanan et al.   Stem Cells International

Engineering hybrid exosomes by membrane fusion with liposomes

(2016) Yuko T. Sato et al.   Scientific Reports

MSC Transplantation Improves Osteopenia via Epigenetic Regulation of Notch Signaling in Lupus

(2015) Shiyu Liu et al.   Cell Metabolism

Stabilization of Exosome-targeting Peptides via Engineered Glycosylation

(2015) Michelle E. Hung et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Exosomes as drug delivery vehicles for Parkinson's disease therapy

(2015) Matthew J. Haney et al.   JOURNAL OF CONTROLLED RELEASE

Exosomes released from human induced pluripotent stem cells-derived MSCs facilitate cutaneous wound healing by promoting collagen synthesis and angiogenesis

(2015) Jieyuan Zhang et al.   Journal of Translational Medicine

Effective Dystrophin Restoration by a Novel Muscle-Homing Peptide–Morpholino Conjugate in Dystrophin-Deficient mdx Mice

(2014) Xianjun Gao et al.   MOLECULAR THERAPY

Systemic exosomal siRNA delivery reduced alpha-synuclein aggregates in brains of transgenic mice

(2014) J. Mark Cooper et al.   MOVEMENT DISORDERS

Identification of Serum microRNA Biomarkers for Tuberculosis Using RNA-seq

(2014) Hongtai Zhang et al.   PLoS One

A doxorubicin delivery platform using engineered natural membrane vesicle exosomes for targeted tumor therapy

(2013) Yanhua Tian et al.   BIOMATERIALS

Click Chemistry for Drug Development and Diverse Chemical–Biology Applications

(2013) Prakasam Thirumurugan et al.   CHEMICAL REVIEWS

Electroporation-induced siRNA precipitation obscures the efficiency of siRNA loading into extracellular vesicles

(2013) Sander A.A. Kooijmans et al.   JOURNAL OF CONTROLLED RELEASE

A delivery system targeting bone formation surfaces to facilitate RNAi-based anabolic therapy

(2012) Ge Zhang et al.   NATURE MEDICINE

Directing mesenchymal stem cells to bone to augment bone formation and increase bone mass

(2012) Min Guan et al.   NATURE MEDICINE

Delivery of siRNA to the mouse brain by systemic injection of targeted exosomes

(2011) Lydia Alvarez-Erviti et al.   NATURE BIOTECHNOLOGY