A novel PPARɣ ligand, PPZ023, overcomes radioresistance via ER stress and cell death in human non-small-cell lung cancer cells

The degradation pathway of a model misfolded protein is determined by aggregation propensity

(2018) Zhihao Sun et al.   MOLECULAR BIOLOGY OF THE CELL

Transcription Factor C/EBP Homologous Protein in Health and Diseases

(2017) Yuan Yang et al.   Frontiers in Immunology

The Role of the PERK/eIF2α/ATF4/CHOP Signaling Pathway in Tumor Progression During Endoplasmic Reticulum Stress

(2016) W. Rozpedek et al.   CURRENT MOLECULAR MEDICINE

Methamphetamine-mediated endoplasmic reticulum (ER) stress induces type-1 programmed cell death in astrocytes via ATF6, IRE1α and PERK pathways

(2016) Ankit Shah et al.   Oncotarget

Metformin, an Old Drug, Brings a New Era to Cancer Therapy

(2015) Huan He et al.   CANCER JOURNAL

Therapeutic Implications for Overcoming Radiation Resistance in Cancer Therapy

(2015) Byeong Kim et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Role of the unfolded protein response, GRP78 and GRP94 in organ homeostasis

(2015) Genyuan Zhu et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Regulated Cell Death: Signaling and Mechanisms

(2014) Avi Ashkenazi et al.   Annual Review of Cell and Developmental Biology

Type 2 diabetes and the risk of mortality among patients with prostate cancer

(2014) Leah Bensimon et al.   CANCER CAUSES & CONTROL

Curcumin induces apoptosis in human gastric carcinoma AGS cells and colon carcinoma HT-29 cells through mitochondrial dysfunction and endoplasmic reticulum stress

(2013) Aili Cao et al.   APOPTOSIS

Basic Mechanisms of Therapeutic Resistance to Radiation and Chemotherapy in Lung Cancer

(2013) Henning Willers et al.   CANCER JOURNAL

Non-small cell lung cancer cells survived ionizing radiation treatment display cancer stem cell and epithelial-mesenchymal transition phenotypes

(2013) Roberto Gomez-Casal et al.   Molecular Cancer

Cancer statistics, 2012

(2012) Rebecca Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Gene regulatory network of unfolded protein response genes in endoplasmic reticulum stress

(2012) Sayuri Takayanagi et al.   CELL STRESS & CHAPERONES

The role of endoplasmic reticulum stress and the unfolded protein response in fibrosis

(2012) Stefania Lenna et al.   CURRENT OPINION IN RHEUMATOLOGY

CHOP is a multifunctional transcription factor in the ER stress response

(2012) H. Nishitoh   JOURNAL OF BIOCHEMISTRY

Low-Dose Valproic Acid Enhances Radiosensitivity of Prostate Cancer through Acetylated p53-Dependent Modulation of Mitochondrial Membrane Potential and Apoptosis

(2011) X. Chen et al.   MOLECULAR CANCER RESEARCH

Combined treatment with the Cox-2 inhibitor niflumic acid and PPARγ ligand ciglitazone induces ER stress/caspase-8-mediated apoptosis in human lung cancer cells

(2010) Byeong Mo Kim et al.   CANCER LETTERS

Disulfide bonds in ER protein folding and homeostasis

(2010) Matthias J Feige et al.   CURRENT OPINION IN CELL BIOLOGY

Role of the Unfolded Protein Response Regulator GRP78/BiP in Development, Cancer, and Neurological Disorders

(2009) Miao Wang et al.   ANTIOXIDANTS & REDOX SIGNALING

Oxidative Folding: Cellular Strategies for Dealing with the Resultant Equimolar Production of Reactive Oxygen Species

(2009) Yuichiro Shimizu et al.   ANTIOXIDANTS & REDOX SIGNALING

Staurosporine induces apoptosis in human papillomavirus positive oral cancer cells at G2/M phase by disrupting mitochondrial membrane potential and modulation of cell cytoskeleton

(2009) Jayanta Sarkar et al.   ORAL ONCOLOGY

Regression of Drug-Resistant Lung Cancer by the Combination of Rosiglitazone and Carboplatin

(2008) G. D. Girnun et al.   CLINICAL CANCER RESEARCH

Antioxidants reduce endoplasmic reticulum stress and improve protein secretion

(2008) J. D. Malhotra et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

NF-κB-MediatedHER2Overexpression inRadiation-Adaptive Resistance

(2008) Ning Cao et al.   RADIATION RESEARCH