标题
LSD
1 inhibition induces differentiation and cell death in Merkel cell carcinoma
作者
关键词
-
出版物
EMBO Molecular Medicine
Volume -, Issue -, Pages -
出版商
EMBO
发表日期
2020-10-07
DOI
10.15252/emmm.202012525
参考文献
相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。- The nf-core framework for community-curated bioinformatics pipelines
- (2020) Philip A. Ewels et al. NATURE BIOTECHNOLOGY
- Merkel cell polyomavirus activates LSD1-mediated blockade of non-canonical BAF to regulate transformation and tumorigenesis
- (2020) Donglim Esther Park et al. NATURE CELL BIOLOGY
- Ordino: a visual cancer analysis tool for ranking and exploring genes, cell lines, and tissue samples
- (2019) Marc Streit et al. BIOINFORMATICS
- Targeting NOTCH activation in small cell lung cancer through LSD1 inhibition
- (2019) Arnaud Augert et al. Science Signaling
- g:Profiler: a web server for functional enrichment analysis and conversions of gene lists (2019 update)
- (2019) Uku Raudvere et al. NUCLEIC ACIDS RESEARCH
- The cellular basis of mechanosensory Merkel-cell innervation during development
- (2019) Blair A Jenkins et al. eLife
- Quantification of experimentally induced nucleotide conversions in high-throughput sequencing datasets
- (2019) Tobias Neumann et al. BMC BIOINFORMATICS
- Metascape provides a biologist-oriented resource for the analysis of systems-level datasets
- (2019) Yingyao Zhou et al. Nature Communications
- Improved CUT&RUN chromatin profiling tools
- (2019) Michael P Meers et al. eLife
- Conversion of Sox2-dependent Merkel cell carcinoma to a differentiated neuron-like phenotype by T antigen inhibition
- (2019) Alexis Harold et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- LSD1 Inhibition Promotes Epithelial Differentiation through Derepression of Fate-Determining Transcription Factors
- (2019) Shaun Egolf et al. Cell Reports
- Re-programing Chromatin with a Bifunctional LSD1/HDAC Inhibitor Induces Therapeutic Differentiation in DIPG
- (2019) Jamie N. Anastas et al. CANCER CELL
- LSD1/KDM1A inhibitors in clinical trials: advances and prospects
- (2019) Yuan Fang et al. Journal of Hematology & Oncology
- ORY-1001, a Potent and Selective Covalent KDM1A Inhibitor, for the Treatment of Acute Leukemia
- (2018) Tamara Maes et al. CANCER CELL
- LSD1 Ablation Stimulates Anti-tumor Immunity and Enables Checkpoint Blockade
- (2018) Wanqiang Sheng et al. CELL
- LSD1 activates a lethal prostate cancer gene network independently of its demethylase function
- (2018) Archana Sehrawat et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- SLAM-seq defines direct gene-regulatory functions of the BRD4-MYC axis
- (2018) Matthias Muhar et al. SCIENCE
- Targeting the CoREST complex with dual histone deacetylase and demethylase inhibitors
- (2018) Jay H. Kalin et al. Nature Communications
- Enhancer Activation by Pharmacologic Displacement of LSD1 from GFI1 Induces Differentiation in Acute Myeloid Leukemia
- (2018) Alba Maiques-Diaz et al. Cell Reports
- The biology and treatment of Merkel cell carcinoma: current understanding and research priorities
- (2018) Paul W. Harms et al. Nature Reviews Clinical Oncology
- The Pfam protein families database in 2019
- (2018) Sara El-Gebali et al. NUCLEIC ACIDS RESEARCH
- Neuroendocrine Key Regulator Gene Expression in Merkel Cell Carcinoma
- (2018) Emil Chteinberg et al. NEOPLASIA
- Insulinoma-associated 1: A novel nuclear marker in Merkel cell carcinoma (cutaneous neuroendocrine carcinoma)
- (2017) Patrick S. Rush et al. JOURNAL OF CUTANEOUS PATHOLOGY
- Benzoisoquinolinediones as Potent and Selective Inhibitors of BRPF2 and TAF1/TAF1L Bromodomains
- (2017) Léa Bouché et al. JOURNAL OF MEDICINAL CHEMISTRY
- Prediction of potent shRNAs with a sequential classification algorithm
- (2017) Raphael Pelossof et al. NATURE BIOTECHNOLOGY
- An improved ATAC-seq protocol reduces background and enables interrogation of frozen tissues
- (2017) M Ryan Corces et al. NATURE METHODS
- Thiol-linked alkylation of RNA to assess expression dynamics
- (2017) Veronika A Herzog et al. NATURE METHODS
- Epigenetic plasticity and the hallmarks of cancer
- (2017) William A. Flavahan et al. SCIENCE
- TGF-β Family Signaling in Neural and Neuronal Differentiation, Development, and Function
- (2017) Emily A. Meyers et al. Cold Spring Harbor Perspectives in Biology
- Avelumab in patients with chemotherapy-refractory metastatic Merkel cell carcinoma: a multicentre, single-group, open-label, phase 2 trial
- (2016) Howard L Kaufman et al. LANCET ONCOLOGY
- Targeting the cancer epigenome for therapy
- (2016) Peter A. Jones et al. NATURE REVIEWS GENETICS
- PD-1 Blockade with Pembrolizumab in Advanced Merkel-Cell Carcinoma
- (2016) Paul T. Nghiem et al. NEW ENGLAND JOURNAL OF MEDICINE
- deepTools2: a next generation web server for deep-sequencing data analysis
- (2016) Fidel Ramírez et al. NUCLEIC ACIDS RESEARCH
- Response rates and durability of chemotherapy among 62 patients with metastatic Merkel cell carcinoma
- (2016) Jayasri G. Iyer et al. Cancer Medicine
- A DNA Hypomethylation Signature Predicts Antitumor Activity of LSD1 Inhibitors in SCLC
- (2015) Helai P. Mohammad et al. CANCER CELL
- The Distinctive Mutational Spectra of Polyomavirus-Negative Merkel Cell Carcinoma
- (2015) Paul William Harms et al. CANCER RESEARCH
- Ectopic Atoh1 expression drives Merkel cell production in embryonic, postnatal and adult mouse epidermis
- (2015) S. M. Ostrowski et al. DEVELOPMENT
- NeuroD1 reprograms chromatin and transcription factor landscapes to induce the neuronal program
- (2015) A. Pataskar et al. EMBO JOURNAL
- A Specific LSD1/KDM1A Isoform Regulates Neuronal Differentiation through H3K9 Demethylation
- (2015) Benoit Laurent et al. MOLECULAR CELL
- Pharmacological targeting of the Wdr5-MLL interaction in C/EBPα N-terminal leukemia
- (2015) Florian Grebien et al. Nature Chemical Biology
- Structure and Property Guided Design in the Identification of PRMT5 Tool Compound EPZ015666
- (2015) Kenneth W. Duncan et al. ACS Medicinal Chemistry Letters
- Embryonic maturation of epidermal Merkel cells is controlled by a redundant transcription factor network
- (2014) C. N. Perdigoto et al. DEVELOPMENT
- MS Amanda, a Universal Identification Algorithm Optimized for High Accuracy Tandem Mass Spectra
- (2014) Viktoria Dorfer et al. JOURNAL OF PROTEOME RESEARCH
- Interplay between the Cancer Genome and Epigenome
- (2013) Hui Shen et al. CELL
- Polycomb subunits Ezh1 and Ezh2 regulate the Merkel cell differentiation program in skin stem cells
- (2013) Evan S Bardot et al. EMBO JOURNAL
- Smart-seq2 for sensitive full-length transcriptome profiling in single cells
- (2013) Simone Picelli et al. NATURE METHODS
- An Optimized microRNA Backbone for Effective Single-Copy RNAi
- (2013) Christof Fellmann et al. Cell Reports
- STAR: ultrafast universal RNA-seq aligner
- (2012) Alexander Dobin et al. BIOINFORMATICS
- The Histone Demethylase KDM1A Sustains the Oncogenic Potential of MLL-AF9 Leukemia Stem Cells
- (2012) William J. Harris et al. CANCER CELL
- Inhibiting Interactions of Lysine Demethylase LSD1 with Snail/Slug Blocks Cancer Cell Invasion
- (2012) G. Ferrari-Amorotti et al. CANCER RESEARCH
- Inhibition of the LSD1 (KDM1A) demethylase reactivates the all-trans-retinoic acid differentiation pathway in acute myeloid leukemia
- (2012) Tino Schenk et al. NATURE MEDICINE
- Control of neuronal differentiation by sumoylation of BRAF35, a subunit of the LSD1-CoREST histone demethylase complex
- (2012) M. Ceballos-Chavez et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Universal and Confident Phosphorylation Site Localization Using phosphoRS
- (2011) Thomas Taus et al. JOURNAL OF PROTEOME RESEARCH
- LSD1 regulates the balance between self-renewal and differentiation in human embryonic stem cells
- (2011) Antonio Adamo et al. NATURE CELL BIOLOGY
- Specific inhibition of NF-Y subunits triggers different cell proliferation defects
- (2011) Paolo Benatti et al. NUCLEIC ACIDS RESEARCH
- The CHR promoter element controls cell cycle-dependent gene transcription and binds the DREAM and MMB complexes
- (2011) Gerd A. Müller et al. NUCLEIC ACIDS RESEARCH
- Merkel Cell Polyomavirus-Infected Merkel Cell Carcinoma Cells Require Expression of Viral T Antigens
- (2010) R. Houben et al. JOURNAL OF VIROLOGY
- Simple Combinations of Lineage-Determining Transcription Factors Prime cis-Regulatory Elements Required for Macrophage and B Cell Identities
- (2010) Sven Heinz et al. MOLECULAR CELL
- Selective inhibition of BET bromodomains
- (2010) Panagis Filippakopoulos et al. NATURE
- The Sequence Alignment/Map format and SAMtools
- (2009) H. Li et al. BIOINFORMATICS
- Jalview Version 2--a multiple sequence alignment editor and analysis workbench
- (2009) A. M. Waterhouse et al. BIOINFORMATICS
- Systematic identification of cell cycle-dependent yeast nucleocytoplasmic shuttling proteins by prediction of composite motifs
- (2009) S. Kosugi et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Recent developments in the MAFFT multiple sequence alignment program
- (2008) K. Katoh et al. BRIEFINGS IN BIOINFORMATICS
- Clonal Integration of a Polyomavirus in Human Merkel Cell Carcinoma
- (2008) H. Feng et al. SCIENCE
Create your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create NowBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started