A Notch3-Marked Subpopulation of Vascular Smooth Muscle Cells Is the Cell of Origin for Occlusive Pulmonary Vascular Lesions

TNF Induces Obliterative Pulmonary Vascular Disease in a Novel Model of Connective Tissue Disease Associated Pulmonary Arterial Hypertension (CTD‐PAH)

(2020) Richard D. Bell et al.   Arthritis & Rheumatology

Phenotypically-Silent Bone Morphogenetic Protein Receptor 2 ( Bmpr2 ) Mutations Predispose Rats to Inflammation-Induced Pulmonary Arterial Hypertension by Enhancing The Risk for Neointimal Transformation

(2019) Wen Tian et al.   CIRCULATION

Th2 CD4 + T Cells Are Necessary and Sufficient for Schistosoma‐ Pulmonary Hypertension

(2019) Rahul Kumar et al.   Journal of the American Heart Association

Chronic Inflammation Within the Vascular Wall in Pulmonary Arterial Hypertension: More than a Spectator

(2019) Alice Huertas et al.   CARDIOVASCULAR RESEARCH

A Twist on Pulmonary Vascular Remodeling: Endothelial to Mesenchymal Transition?

(2018) Grazyna Kwapiszewska et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Dynamic and diverse changes in the functional properties of vascular smooth muscle cells in pulmonary hypertension

(2018) Kurt R Stenmark et al.   CARDIOVASCULAR RESEARCH

Mapping the Mouse Cell Atlas by Microwell-Seq

(2018) Xiaoping Han et al.   CELL

Pulmonary vascular endothelium: the orchestra conductor in respiratory diseases

(2018) Alice Huertas et al.   EUROPEAN RESPIRATORY JOURNAL

How does inflammation contribute to pulmonary hypertension?

(2018) Rahul Kumar et al.   EUROPEAN RESPIRATORY JOURNAL

Resident cell lineages are preserved in pulmonary vascular remodeling

(2018) Slaven Crnkovic et al.   JOURNAL OF PATHOLOGY

Integrin beta3 regulates clonality and fate of smooth muscle-derived atherosclerotic plaque cells

(2018) Ashish Misra et al.   Nature Communications

New and Emerging Therapies for Pulmonary Arterial Hypertension

(2018) Edda Spiekerkoetter et al.   Annual Review of Medicine

Pulmonary Venous Remodeling in Pulmonary Hypertension

(2018) Jane A. Leopold   CIRCULATION

A revised airway epithelial hierarchy includes CFTR-expressing ionocytes

(2018) Daniel T. Montoro et al.   NATURE

A molecular atlas of cell types and zonation in the brain vasculature

(2018) Michael Vanlandewijck et al.   NATURE

Pathology and pathobiology of pulmonary hypertension: state of the art and research perspectives

(2018) Marc Humbert et al.   EUROPEAN RESPIRATORY JOURNAL

Haemodynamic definitions and updated clinical classification of pulmonary hypertension

(2018) Gérald Simonneau et al.   EUROPEAN RESPIRATORY JOURNAL

Single-cell transcriptomics of 20 mouse organs creates a Tabula Muris

(2018) et al.   NATURE

Epidemiology and treatment of pulmonary arterial hypertension

(2017) Edmund M. T. Lau et al.   Nature Reviews Cardiology

NOTCH1 is a mechanosensor in adult arteries

(2017) Julia J. Mack et al.   Nature Communications

Endothelial dysfunction in pulmonary arterial hypertension: an evolving landscape (2017 Grover Conference Series)

(2017) Benoît Ranchoux et al.   Pulmonary Circulation

Global Pulmonary Vascular Remodeling in Pulmonary Hypertension Associated With Heart Failure and Preserved or Reduced Ejection Fraction

(2017) Ahmed U. Fayyaz et al.   CIRCULATION

Intrapulmonary Bronchopulmonary Anastomoses and Plexiform Lesions in Idiopathic Pulmonary Arterial Hypertension

(2016) Csaba Galambos et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Vascular Smooth Muscle Cells

(2016) Mark W. Majesky   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Endothelial-to-Mesenchymal Transition

(2016) Kurt R. Stenmark et al.   CIRCULATION

In Pulmonary Arterial Hypertension, Reduced BMPR2 Promotes Endothelial-to-Mesenchymal Transition via HMGA1 and Its Target SlugCLINICAL PERSPECTIVE

(2016) Rachel K. Hopper et al.   CIRCULATION

Prolyl-4 Hydroxylase 2 (PHD2) Deficiency in Endothelial Cells and Hematopoietic Cells Induces Obliterative Vascular Remodeling and Severe Pulmonary Arterial Hypertension in Mice and Humans Through Hypoxia-Inducible Factor-2αCLINICAL PERSPECTIVE

(2016) Zhiyu Dai et al.   CIRCULATION

Vascular Smooth Muscle Cells in Atherosclerosis

(2016) Martin R. Bennett et al.   CIRCULATION RESEARCH

Extensive Proliferation of a Subset of Differentiated, yet Plastic, Medial Vascular Smooth Muscle Cells Contributes to Neointimal Formation in Mouse Injury and Atherosclerosis ModelsNovelty and Significance

(2016) Joel Chappell et al.   CIRCULATION RESEARCH

BMPR2mutation status influences bronchial vascular changes in pulmonary arterial hypertension

(2016) Maria-Rosa Ghigna et al.   EUROPEAN RESPIRATORY JOURNAL

The Causal Role of IL-4 and IL-13 inSchistosoma mansoniPulmonary Hypertension

(2015) Rahul Kumar et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Endothelial-to-Mesenchymal Transition in Pulmonary Hypertension

(2015) B. Ranchoux et al.   CIRCULATION

Advanced CUBIC protocols for whole-brain and whole-body clearing and imaging

(2015) Etsuo A Susaki et al.   Nature Protocols

Interleukin-6/interleukin-21 signaling axis is critical in the pathogenesis of pulmonary arterial hypertension

(2015) Takahiro Hashimoto-Kataoka et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Smooth muscle cell progenitors are primed to muscularize in pulmonary hypertension

(2015) Abdul Q. Sheikh et al.   Science Translational Medicine

Inflammation and Immunity in the Pathogenesis of Pulmonary Arterial Hypertension

(2014) Marlene Rabinovitch et al.   CIRCULATION RESEARCH

Adventitial Fibroblasts Induce a Distinct Proinflammatory/Profibrotic Macrophage Phenotype in Pulmonary Hypertension

(2014) Karim C. El Kasmi et al.   JOURNAL OF IMMUNOLOGY

Defining a mesenchymal progenitor niche at single-cell resolution

(2014) M. E. Kumar et al.   SCIENCE

Transforming Growth Factor-β Signaling Promotes Pulmonary Hypertension Caused by Schistosoma Mansoni

(2013) Brian B. Graham et al.   CIRCULATION

Endothelial Fate Mapping in Mice With Pulmonary Hypertension

(2013) Lina Qiao et al.   CIRCULATION

FK506 activates BMPR2, rescues endothelial dysfunction, and reverses pulmonary hypertension

(2013) Edda Spiekerkoetter et al.   JOURNAL OF CLINICAL INVESTIGATION

A brief overview of mouse models of pulmonary arterial hypertension: problems and prospects

(2012) Jose Gomez-Arroyo et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Radial Construction of an Arterial Wall

(2012) Daniel M. Greif et al.   DEVELOPMENTAL CELL

Molecular pathogenesis of pulmonary arterial hypertension

(2012) Marlene Rabinovitch   JOURNAL OF CLINICAL INVESTIGATION

An artery-specific fluorescent dye for studying neurovascular coupling

(2012) Zhiming Shen et al.   NATURE METHODS

Chronic Allergic Inflammation Causes Vascular Remodeling and Pulmonary Hypertension in Bmpr2 Hypomorph and Wild-Type Mice

(2012) Elizabeth M. Mushaben et al.   PLoS One

Germ-layer and lineage-restricted stem/progenitors regenerate the mouse digit tip

(2011) Yuval Rinkevich et al.   NATURE

Notch Lineages and Activity in Intestinal Stem Cells Determined by a New Set of Knock-In Mice

(2011) Silvia Fre et al.   PLoS One

Inducible Cx40-Cre expression in the cardiac conduction system and arterial endothelial cells

(2010) Sabrina Beyer et al.   GENESIS

Notch3 signaling promotes the development of pulmonary arterial hypertension

(2009) Xiaodong Li et al.   NATURE MEDICINE

A robust and high-throughput Cre reporting and characterization system for the whole mouse brain

(2009) Linda Madisen et al.   NATURE NEUROSCIENCE

Induction of Vascular Remodeling in the Lung by Chronic House Dust Mite Exposure

(2008) Kristina Rydell-Törmänen et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Efficient temporally-controlled targeted mutagenesis in smooth muscle cells of the adult mouse

(2008) Olivia Wendling et al.   GENESIS

Pulmonary arterial remodeling induced by a Th2 immune response

(2008) Eleen Daley et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The branching programme of mouse lung development

(2008) Ross J. Metzger et al.   NATURE