Rapid intestinal glucuronidation and hepatic glucuronide recycling contributes significantly to the enterohepatic circulation of icaritin and its glucuronides in vivo

Application of ultra high-performance liquid chromatography tandem mass spectrometry to investigate the regioselective glucuronidation of icaritin in vitro

(2018) Yi Rong et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Human UDP-Glucuronosyltransferase 2B4 and 2B7 Are Responsible for Naftopidil Glucuronidation in Vitro

(2018) Xia-Wen Liu et al.   Frontiers in Pharmacology

Disposition of flavonoids via recycling: Direct biliary excretion of enterically or extrahepatically derived flavonoid glucuronides

(2016) Min Zeng et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Nuclear Multidrug Resistance-Related Protein 1 Is Highly Associated with Better Prognosis of Human Mucoepidermoid Carcinoma through the Suppression of Cell Proliferation, Migration and Invasion

(2016) Bo-Lei Cai et al.   PLoS One

Species- and gender-dependent differences in the glucuronidation of a flavonoid glucoside and its aglycone determined using expressed UGT enzymes and microsomes

(2015) Peimin Dai et al.   BIOPHARMACEUTICS & DRUG DISPOSITION

Hepatic Disposition of Gemfibrozil and Its Major Metabolite Gemfibrozil 1-O-β-Glucuronide

(2015) Emi Kimoto et al.   MOLECULAR PHARMACEUTICS

Erratum: Advances in targeted therapies for hepatocellular carcinoma in the genomic era

(2015) Josep M. Llovet et al.   Nature Reviews Clinical Oncology

Biodistribution evaluation of icaritin in rats by ultra-performance liquid chromatography–tandem mass spectrometry

(2014) Shuang-Qing Zhang   JOURNAL OF ETHNOPHARMACOLOGY

Chemopreventive strategies in hepatocellular carcinoma

(2013) Siddharth Singh et al.   Nature Reviews Gastroenterology & Hepatology

Organic anion transporting polypeptides OATP1B1 and OATP1B3 and their genetic variants influence the pharmacokinetics and pharmacodynamics of raloxifene

(2012) Tina Trdan Lušin et al.   Journal of Translational Medicine

Oral absorption and excretion of icaritin, an aglycone and also active metabolite of prenylflavonoids from the Chinese medicine Herba Epimedii in rats

(2012) Qi Chang et al.   PHYTOMEDICINE

Antitumor Activity of Artemisinin and Its Derivatives: From a Well-Known Antimalarial Agent to a Potential Anticancer Drug

(2011) Maria P. Crespo-Ortiz et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

Xenobiotic, Bile Acid, and Cholesterol Transporters: Function and Regulation

(2010) C. D. Klaassen et al.   PHARMACOLOGICAL REVIEWS

Tissue Distribution, Ontogeny, and Hormonal Regulation of Xenobiotic Transporters in Mouse Kidneys

(2009) X. Cheng et al.   DRUG METABOLISM AND DISPOSITION