Retinal imaging in Alzheimer's and neurodegenerative diseases

Identification of early pericyte loss and vascular amyloidosis in Alzheimer’s disease retina

(2020) Haoshen Shi et al.   ACTA NEUROPATHOLOGICA

Developing retinal biomarkers for the earliest stages of Alzheimer's disease: What we know, what we don't, and how to move forward

(2020) Jessica Alber et al.   Alzheimers & Dementia

Evaluation of macular thickness and volume tested by optical coherence tomography as biomarkers for Alzheimer’s disease in a memory clinic

(2020) Domingo Sánchez et al.   Scientific Reports

A CNN-aided method to predict glaucoma progression using DARC (Detection of Apoptosing Retinal Cells)

(2020) Eduardo M. Normando et al.   EXPERT REVIEW OF MOLECULAR DIAGNOSTICS

Retinal nerve fiber layer thickness predicts CSF amyloid/tau before cognitive decline

(2020) Samuel Asanad et al.   PLoS One

Functional and morphological changes of the retinal vessels in Alzheimer’s disease and mild cognitive impairment

(2019) Giuseppe Querques et al.   Scientific Reports

A pilot study of fluorescence lifetime imaging ophthalmoscopy in preclinical Alzheimer’s disease

(2019) SriniVas R. Sadda et al.   EYE

Light-Induced Pupillary Responses in Alzheimer's Disease

(2019) Pratik S. Chougule et al.   Frontiers in Neurology

Identification of Retinal Biomarkers in Alzheimer’s Disease Using Optical Coherence Tomography: Recent Insights, Challenges, and Opportunities

(2019) Delia Cabrera DeBuc et al.   Journal of Clinical Medicine

Neuroinflammatory Processes, A1 Astrocyte Activation and Protein Aggregation in the Retina of Alzheimer’s Disease Patients, Possible Biomarkers for Early Diagnosis

(2019) Alfonso Grimaldi et al.   Frontiers in Neuroscience

In Vivo Assessment of Retinal Biomarkers by Hyperspectral Imaging: Early Detection of Alzheimer’s Disease

(2019) Swati S. More et al.   ACS Chemical Neuroscience

Non-invasive in vivo hyperspectral imaging of the retina for potential biomarker use in Alzheimer’s disease

(2019) Xavier Hadoux et al.   Nature Communications

Levels of Retinal Amyloid-β Correlate with Levels of Retinal IAPP and Hippocampal Amyloid-β in Neuropathologically Evaluated Individuals

(2019) Nina Schultz et al.   JOURNAL OF ALZHEIMERS DISEASE

Pupillometry evaluation of melanopsin retinal ganglion cell function and sleep-wake activity in pre-symptomatic Alzheimer’s disease

(2019) Angela J. Oh et al.   PLoS One

Estimation of lifetime risks of Alzheimer's disease dementia using biomarkers for preclinical disease

(2018) Ron Brookmeyer et al.   Alzheimers & Dementia

Forecasting the prevalence of preclinical and clinical Alzheimer's disease in the United States

(2018) Ron Brookmeyer et al.   Alzheimers & Dementia

NIA-AA Research Framework: Toward a biological definition of Alzheimer's disease

(2018) Clifford R. Jack et al.   Alzheimers & Dementia

A Decade of Blood Biomarkers for Alzheimer’s Disease Research: An Evolving Field, Improving Study Designs, and the Challenge of Replication

(2018) Liu Shi et al.   JOURNAL OF ALZHEIMERS DISEASE

High performance plasma amyloid-β biomarkers for Alzheimer’s disease

(2018) Akinori Nakamura et al.   NATURE

Inflammation, neurodegeneration and protein aggregation in the retina as ocular biomarkers for Alzheimer’s disease in the 3xTg-AD mouse model

(2018) Alfonso Grimaldi et al.   Cell Death & Disease

Potential Utility of Retinal Imaging for Alzheimer’s Disease: A Review

(2018) Huan Liao et al.   Frontiers in Aging Neuroscience

Association of Retinal Neurodegeneration on Optical Coherence Tomography With Dementia

(2018) Unal Mutlu et al.   JAMA Neurology

Association of Retinal Nerve Fiber Layer Thinning With Current and Future Cognitive Decline

(2018) Fang Ko et al.   JAMA Neurology

Longitudinal cognitive and biomarker changes in dominantly inherited Alzheimer disease

(2018) Eric McDade et al.   NEUROLOGY

Spectral-Domain OCT Measurements in Alzheimer’s Disease

(2018) Victor T.T. Chan et al.   OPHTHALMOLOGY

Different curcumin forms selectively bind fibrillar amyloid beta in post mortem Alzheimer’s disease brains: Implications for in-vivo diagnostics

(2018) Jurre den Haan et al.   Acta Neuropathologica Communications

Blood-based biomarkers for Alzheimer disease: mapping the road to the clinic

(2018) Harald Hampel et al.   Nature Reviews Neurology

Impact of mydriasis in fluorescence lifetime imaging ophthalmoscopy

(2018) SriniVas R. Sadda et al.   PLoS One

Association of Preclinical Alzheimer Disease With Optical Coherence Tomographic Angiography Findings

(2018) Bliss Elizabeth O’Bryhim et al.   JAMA Ophthalmology

Investigating Multimodal Diagnostic Eye Biomarkers of Cognitive Impairment by Measuring Vascular and Neurogenic Changes in the Retina

(2018) Delia Cabrera DeBuc et al.   Frontiers in Physiology

Melanopsin Retinal Ganglion Cells and Pupil: Clinical Implications for Neuro-Ophthalmology

(2018) Chiara La Morgia et al.   Frontiers in Neurology

Amyloid-beta and phosphorylated tau in post-mortem Alzheimer’s disease retinas

(2018) Jurre den Haan et al.   Acta Neuropathologica Communications

Altered Macular Microvasculature in Mild Cognitive Impairment and Alzheimer Disease

(2017) Hong Jiang et al.   JOURNAL OF NEURO-OPHTHALMOLOGY

Beta-amyloid sequelae in the eye: a critical review on its diagnostic significance and clinical relevance in Alzheimer’s disease

(2017) T M Shah et al.   MOLECULAR PSYCHIATRY

Vascular basement membranes as pathways for the passage of fluid into and out of the brain

(2016) Alan W. J. Morris et al.   ACTA NEUROPATHOLOGICA

Preclinical Alzheimer's disease: Definition, natural history, and diagnostic criteria

(2016) Bruno Dubois et al.   Alzheimers & Dementia

The retina as an early biomarker of neurodegeneration in a rotenone-induced model of Parkinson’s disease: evidence for a neuroprotective effect of rosiglitazone in the eye and brain

(2016) Eduardo Maria Normando et al.   Acta Neuropathologica Communications

Retinal amyloid peptides and complement factor H in transgenic models of Alzheimerʼs disease

(2016) Peter N. Alexandrov et al.   NEUROREPORT

Melanopsin retinal ganglion cell loss in Alzheimer disease

(2015) Chiara La Morgia et al.   ANNALS OF NEUROLOGY

The down syndrome biomarker initiative (DSBI) pilot: proof of concept for deep phenotyping of Alzheimer’s disease biomarkers in down syndrome

(2015) Michael S. Rafii et al.   Frontiers in Behavioral Neuroscience

Associations Between Biomarkers and Age in the Presenilin 1 E280A Autosomal Dominant Alzheimer Disease Kindred

(2015) Adam S. Fleisher et al.   JAMA Neurology

Retinal fluorescence lifetime imaging ophthalmoscopy measures depend on the severity of Alzheimer's disease

(2014) Susanne Jentsch et al.   ACTA OPHTHALMOLOGICA

The A4 Study: Stopping AD Before Symptoms Begin?

(2014) R. A. Sperling et al.   Science Translational Medicine

Developing novel blood-based biomarkers for Alzheimer's disease

(2013) Heather M. Snyder et al.   Alzheimers & Dementia

Long-Term In Vivo Imaging of Fibrillar Tau in the Retina of P301S Transgenic Mice

(2013) Christian Schön et al.   PLoS One

Toward defining the preclinical stages of Alzheimer’s disease: Recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease

(2011) Reisa A. Sperling et al.   Alzheimers & Dementia

Testing the Right Target and Right Drug at the Right Stage

(2011) R. A. Sperling et al.   Science Translational Medicine

Intracellular coenzymes as natural biomarkers for metabolic activities and mitochondrial anomalies

(2010) Ahmed A Heikal   Biomarkers in Medicine

Identification of amyloid plaques in retinas from Alzheimer's patients and noninvasive in vivo optical imaging of retinal plaques in a mouse model

(2010) Maya Koronyo-Hamaoui et al.   NEUROIMAGE