Neuron‐specific deletion of CuZnSOD leads to an advanced sarcopenic phenotype in older mice

Molecular changes associated with spinal cord aging

(2020) Katarzyna M. Piekarz et al.   GeroScience

Mitochondrial oxidative stress impairs contractile function but paradoxically increases muscle mass via fibre branching

(2019) Bumsoo Ahn et al.   Journal of Cachexia Sarcopenia and Muscle

Redox responses in skeletal muscle following denervation

(2019) Mattia Scalabrin et al.   Redox Biology

Neuroprotection in Oxidative Stress-Related Neurodegenerative Diseases: Role of Endocannabinoid System Modulation

(2018) Janos Paloczi et al.   ANTIOXIDANTS & REDOX SIGNALING

Nestin-expressing progenitor cells: function, identity and therapeutic implications

(2018) Aurora Bernal et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Loss of mitochondrial protease ClpP protects mice from diet‐induced obesity and insulin resistance

(2018) Shylesh Bhaskaran et al.   EMBO REPORTS

Accelerated sarcopenia in Cu/Zn superoxide dismutase knockout mice

(2018) Sathyaseelan S. Deepa et al.   FREE RADICAL BIOLOGY AND MEDICINE

The Geropathology Grading Platform demonstrates that mice null for Cu/Zn-superoxide dismutase show accelerated biological aging

(2018) Timothy A. Snider et al.   GeroScience

Oxidative stress-induced dysregulation of excitation-contraction coupling contributes to muscle weakness

(2018) Rizwan Qaisar et al.   Journal of Cachexia Sarcopenia and Muscle

Aberrant redox signalling and stress response in age-related muscle decline: Role in inter- and intra-cellular signalling

(2018) Anne McArdle et al.   FREE RADICAL BIOLOGY AND MEDICINE

Role of nerve-muscle interactions and reactive oxygen species in regulation of muscle proteostasis with ageing

(2017) Aphrodite Vasilaki et al.   JOURNAL OF PHYSIOLOGY-LONDON

The effect of lengthening contractions on neuromuscular junction structure in adult and old mice

(2016) Aphrodite Vasilaki et al.   AGE

Role of reactive oxygen species in age-related neuromuscular deficits

(2016) Malcolm J. Jackson et al.   JOURNAL OF PHYSIOLOGY-LONDON

Dach2-Hdac9 signaling regulates reinnervation of muscle endplates

(2015) P. C. D. Macpherson et al.   DEVELOPMENT

Ablation of the Ferroptosis Inhibitor Glutathione Peroxidase 4 in Neurons Results in Rapid Motor Neuron Degeneration and Paralysis

(2015) Liuji Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Neuron specific reduction in CuZnSOD is not sufficient to initiate a full sarcopenia phenotype

(2015) Kavithalakshmi Sataranatarajan et al.   Redox Biology

The Role of Oxidative Stress in Neurodegenerative Diseases

(2015) Geon Ha Kim et al.   Experimental Neurobiology

Presynaptic NCAM Is Required for Motor Neurons to Functionally Expand Their Peripheral Field of Innervation in Partially Denervated Muscles

(2014) P. H. Chipman et al.   JOURNAL OF NEUROSCIENCE

CuZnSOD gene deletion targeted to skeletal muscle leads to loss of contractile force but does not cause muscle atrophy in adult mice

(2013) Yiqiang Zhang et al.   FASEB JOURNAL

Neuron-specific expression of CuZnSOD prevents the loss of muscle mass and function that occurs in homozygous CuZnSOD-knockout mice

(2013) Giorgos K. Sakellariou et al.   FASEB JOURNAL

Dietary restriction attenuates age-associated muscle atrophy by lowering oxidative stress in mice even in complete absence of CuZnSOD

(2012) Young C. Jang et al.   AGING CELL

Shared Resistance to Aging and ALS in Neuromuscular Junctions of Specific Muscles

(2012) Gregorio Valdez et al.   PLoS One

Role of superoxide-nitric oxide interactions in the accelerated age-related loss of muscle mass in mice lacking Cu,Zn superoxide dismutase

(2011) Giorgos K. Sakellariou et al.   AGING CELL

Skeletal muscle weakness due to deficiency of CuZn-superoxide dismutase is associated with loss of functional innervation

(2011) Lisa M. Larkin et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Absence of SOD1 leads to oxidative stress in peripheral nerve and causes a progressive distal motor axonopathy

(2011) Lindsey R. Fischer et al.   EXPERIMENTAL NEUROLOGY

The age-related failure of adaptive responses to contractile activity in skeletal muscle is mimicked in young mice by deletion of Cu,Zn superoxide dismutase

(2010) Aphrodite Vasilaki et al.   AGING CELL

Attenuation of age-related changes in mouse neuromuscular synapses by caloric restriction and exercise

(2010) G. Valdez et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Increased superoxide in vivo accelerates age-associated muscle atrophy through mitochondrial dysfunction and neuromuscular junction degeneration

(2009) Youngmok C. Jang et al.   FASEB JOURNAL

Preferential motor unit loss in the SOD1G93Atransgenic mouse model of amyotrophic lateral sclerosis

(2008) J. Hegedus et al.   JOURNAL OF PHYSIOLOGY-LONDON

Single-neuron labeling with inducible Cre-mediated knockout in transgenic mice

(2008) Paul Young et al.   NATURE NEUROSCIENCE