Ovarian stiffness increases with age in the mammalian ovary and depends on collagen and hyaluronan matrices

Single-Cell Transcriptomic Atlas of Primate Ovarian Aging

(2020) Si Wang et al.   CELL

Low Molecular Weight Hyaluronan Induces an Inflammatory Response in Ovarian Stromal Cells and Impairs Gamete Development In Vitro

(2020) Jennifer E. Rowley et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Ovulation and ovarian wound healing are impaired with advanced reproductive age

(2020) Jamie N. Mara et al.   Aging-US

Mechanical stress accompanied with nuclear rotation is involved in the dormant state of mouse oocytes

(2019) Go Nagamatsu et al.   Science Advances

Metformin Abrogates Age-Associated Ovarian Fibrosis

(2019) Curtis W. McCloskey et al.   CLINICAL CANCER RESEARCH

Tissue-specific Fixation Methods Are Required for Optimal In Situ Visualization of Hyaluronan in the Ovary, Kidney, and Liver

(2019) Jennifer E. Rowley et al.   JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY

Biomechanics and mechanical signaling in the ovary: a systematic review

(2018) Jaimin S. Shah et al.   JOURNAL OF ASSISTED REPRODUCTION AND GENETICS

Molecular organization and mechanical properties of the hyaluronan matrix surrounding the mammalian oocyte

(2018) Antonietta Salustri et al.   MATRIX BIOLOGY

Targeting extracellular matrix stiffness to attenuate disease: From molecular mechanisms to clinical trials

(2018) Marsha C. Lampi et al.   Science Translational Medicine

Label-free analysis of physiological hyaluronan size distribution with a solid-state nanopore sensor

(2018) Felipe Rivas et al.   Nature Communications

Ovarian Follicular Theca Cell Recruitment, Differentiation, and Impact on Fertility: 2017 Update

(2017) JoAnne S Richards et al.   ENDOCRINE REVIEWS

Dysregulated Collagen Homeostasis by Matrix Stiffening and TGF-β1 in Fibroblasts from Idiopathic Pulmonary Fibrosis Patients: Role of FAK/Akt

(2017) Alícia Giménez et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Micromechanical Analysis of the Hyaluronan-Rich Matrix Surrounding the Oocyte Reveals a Uniquely Soft and Elastic Composition

(2016) Xinyue Chen et al.   BIOPHYSICAL JOURNAL

Multi-modal magnetic resonance elastography for noninvasive assessment of ovarian tissue rigidity in vivo

(2015) Charles D. Wood et al.   Acta Biomaterialia

Lineage specification of ovarian theca cells requires multicellular interactions via oocyte and granulosa cells

(2015) Chang Liu et al.   Nature Communications

Hyaluronan – A Functional and Structural Sweet Spot in the Tissue Microenvironment

(2015) James Monslow et al.   Frontiers in Immunology

The Nano-Scale Mechanical Properties of the Extracellular Matrix Regulate Dermal Fibroblast Function

(2014) Volker F. Achterberg et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Promoting extracellular matrix remodeling via ascorbic acid enhances the survival of primary ovarian follicles encapsulated in alginate hydrogels

(2013) David Tagler et al.   BIOTECHNOLOGY AND BIOENGINEERING

Follicle microenvironment-associated alterations in gene expression in the mouse oocyte and its polar body

(2013) Ze-Xu Jiao et al.   FERTILITY AND STERILITY

High-molecular-mass hyaluronan mediates the cancer resistance of the naked mole rat

(2013) Xiao Tian et al.   NATURE

Involvement of hyaluronan synthesis in ovarian follicle growth in rats

(2013) Noriyuki Takahashi et al.   REPRODUCTION

Isolated primate primordial follicles require a rigid physical environment to survive and grow in vitro

(2012) J.E. Hornick et al.   HUMAN REPRODUCTION

Hyal-1 but not hyal-3 deficiency has an impact on ovarian folliculogenesis and female fertility by altering the follistatin/activin/Smad3 pathway and the apoptotic process

(2011) Karine Dumaresq-Doiron et al.   JOURNAL OF CELLULAR PHYSIOLOGY

RNAscope

(2011) Fay Wang et al.   JOURNAL OF MOLECULAR DIAGNOSTICS

Glycomic analyses of ovarian follicles during development and atresia

(2011) Nicholas Hatzirodos et al.   MATRIX BIOLOGY

Rapid and precise scanning helium ion microscope milling of solid-state nanopores for biomolecule detection

(2011) Jijin Yang et al.   NANOTECHNOLOGY

The Timing of the Age at Which Natural Menopause Occurs

(2011) Ellen B. Gold   OBSTETRICS AND GYNECOLOGY CLINICS OF NORTH AMERICA

A macrophage and theca cell-enriched stromal cell population influences growth and survival of immature murine follicles in vitro

(2011) Candace M Tingen et al.   REPRODUCTION

Oxidative Damage Increases and Antioxidant Gene Expression Decreases with Aging in the Mouse Ovary

(2010) J. Lim et al.   BIOLOGY OF REPRODUCTION

Ovarian Aging: Mechanisms and Clinical Consequences

(2009) F. J. Broekmans et al.   ENDOCRINE REVIEWS

Age-associated increase in aneuploidy and changes in gene expression in mouse eggs

(2008) Hua Pan et al.   DEVELOPMENTAL BIOLOGY

Implications of Polycystic Ovary Syndrome on Oocyte Development

(2008) Daniel Dumesic et al.   SEMINARS IN REPRODUCTIVE MEDICINE