Increased marrow adipogenesis does not contribute to age‐dependent appendicular bone loss in female mice

Deletion of PPARγ in Mesenchymal Lineage Cells Protects Against Aging-Induced Cortical Bone Loss in Mice

(2020) Jay Cao et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Scientists rise up against statistical significance

(2019) Valentin Amrhein et al.   NATURE

Aging and lineage allocation changes of bone marrow skeletal (stromal) stem cells

(2019) Jan O. Nehlin et al.   BONE

Congenital lipodystrophy induces severe osteosclerosis

(2019) Wei Zou et al.   PLoS Genetics

The Quest for Osteoporosis Mechanisms and Rational Therapies: How Far We've Come, How Much Further We Need to Go

(2018) Stavros C Manolagas   JOURNAL OF BONE AND MINERAL RESEARCH

Lack of Adipocytes Alters Hematopoiesis in Lipodystrophic Mice

(2018) Anne Wilson et al.   Frontiers in Immunology

Mechanisms of marrow adiposity and its implications for skeletal health

(2017) Annegreet G. Veldhuis-Vlug et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Bone marrow adipocytes promote the regeneration of stem cells and haematopoiesis by secreting SCF

(2017) Bo O. Zhou et al.   NATURE CELL BIOLOGY

Targeting cellular senescence prevents age-related bone loss in mice

(2017) Joshua N Farr et al.   NATURE MEDICINE

Bone marrow adipocytes

(2017) Mark C. Horowitz et al.   Adipocyte

Protein Phosphatase PP5 Controls Bone Mass and the Negative Effects of Rosiglitazone on Bone through Reciprocal Regulation of PPARγ (Peroxisome Proliferator-activated Receptor γ) and RUNX2 (Runt-related Transcription Factor 2)

(2016) Lance A. Stechschulte et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Suppression of Sclerostin Alleviates Radiation-Induced Bone Loss by Protecting Bone-Forming Cells and Their Progenitors Through Distinct Mechanisms

(2016) Abhishek Chandra et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Intermittent Administration of Rapamycin Extends the Life Span of Female C57BL/6J Mice

(2016) Sebastian I. Arriola Apelo et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

PPAR-γ regulates pharmacological but not physiological or pathological osteoclast formation

(2016) Wei Zou et al.   NATURE MEDICINE

An Insulin-Sensitizing Thiazolidinedione, Which Minimally Activates PPARγ, Does Not Cause Bone Loss

(2015) Tomohiro Fukunaga et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Clearance of senescent cells by ABT263 rejuvenates aged hematopoietic stem cells in mice

(2015) Jianhui Chang et al.   NATURE MEDICINE

Highly Selective In Vivo Labeling of Subcutaneous White Adipocyte Precursors with Prx1-Cre

(2015) Joan Sanchez-Gurmaches et al.   Stem Cell Reports

Age-related Marrow Adipogenesis Is Linked to Increased Expression of RANKL

(2014) Sunao Takeshita et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Adult Cartilage-Specific Peroxisome Proliferator–Activated Receptor Gamma Knockout Mice Exhibit the Spontaneous Osteoarthritis Phenotype

(2013) Faezeh Vasheghani et al.   AMERICAN JOURNAL OF PATHOLOGY

Cdc42 and aging of hematopoietic stem cells

(2013) Hartmut Geiger et al.   CURRENT OPINION IN HEMATOLOGY

Dysapoptosis of Osteoblasts and Osteocytes Increases Cancellous Bone Formation But Exaggerates Cortical Porosity With Age

(2013) Robert L Jilka et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Initial Responses of Articular Tissues in a Murine High-Fat Diet-Induced Osteoarthritis Model: Pivotal Role of the IPFP as a Cytokine Fountain

(2013) Munetaka Iwata et al.   PLoS One

Osteoblast-Targeted suppression of PPARγ increases osteogenesis through activation of mTOR signaling

(2013) Hongli Sun et al.   STEM CELLS

Failure to generate bone marrow adipocytes does not protect mice from ovariectomy-induced osteopenia

(2012) Urszula T. Iwaniec et al.   BONE

Loss of wnt/β-catenin signaling causes cell fate shift of preosteoblasts from osteoblasts to adipocytes

(2012) Lige Song et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Standardized nomenclature, symbols, and units for bone histomorphometry: A 2012 update of the report of the ASBMR Histomorphometry Nomenclature Committee

(2012) David W Dempster et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Estrogen receptor-α signaling in osteoblast progenitors stimulates cortical bone accrual

(2012) Maria Almeida et al.   JOURNAL OF CLINICAL INVESTIGATION

Primary human bone marrow adipocytes support TNF-α-induced osteoclast differentiation and function through RANKL expression

(2011) Hisataka Goto et al.   CYTOKINE

Osteoblast connexin43 modulates skeletal architecture by regulating both arms of bone remodeling

(2011) Marcus Watkins et al.   MOLECULAR BIOLOGY OF THE CELL

PGC1β Mediates PPARγ Activation of Osteoclastogenesis and Rosiglitazone-Induced Bone Loss

(2010) Wei Wei et al.   Cell Metabolism

Basic methods in histopathology of joint tissues

(2010) N. Schmitz et al.   OSTEOARTHRITIS AND CARTILAGE

The OARSI histopathology initiative – recommendations for histological assessments of osteoarthritis in the mouse

(2010) S.S. Glasson et al.   OSTEOARTHRITIS AND CARTILAGE

Increased Lipid Oxidation Causes Oxidative Stress, Increased Peroxisome Proliferator-activated Receptor-γ Expression, and Diminished Pro-osteogenic Wnt Signaling in the Skeleton

(2009) Maria Almeida et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Fat and Beyond: The Diverse Biology of PPARγ

(2008) Peter Tontonoz et al.   Annual Review of Biochemistry