Patient-derived organoids and orthotopic xenografts of primary and recurrent gliomas represent relevant patient avatars for precision oncology
出版年份 2020 全文链接
标题
Patient-derived organoids and orthotopic xenografts of primary and recurrent gliomas represent relevant patient avatars for precision oncology
作者
关键词
-
出版物
ACTA NEUROPATHOLOGICA
Volume -, Issue -, Pages -
出版商
Springer Science and Business Media LLC
发表日期
2020-10-03
DOI
10.1007/s00401-020-02226-7
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Revealing and Harnessing Tumour-Associated Microglia/Macrophage Heterogeneity in Glioblastoma
- (2020) Yolanda Pires-Afonso et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Systematic Establishment of Robustness and Standards in Patient-Derived Xenograft Experiments and Analysis
- (2020) Yvonne A. Evrard et al. CANCER RESEARCH
- Challenges to curing primary brain tumours
- (2019) Kenneth Aldape et al. Nature Reviews Clinical Oncology
- Evolutionary Trajectories of IDHWT Glioblastomas Reveal a Common Path of Early Tumorigenesis Instigated Years ahead of Initial Diagnosis
- (2019) Verena Körber et al. CANCER CELL
- Drug Efficacy Comparison of 3D Forming and Preforming Sphere Models with a Micropillar and Microwell Chip Platform
- (2019) Il Doh et al. SLAS Discovery
- Molecular Pathology of Tumors of the Central Nervous System
- (2019) B W Kristensen et al. ANNALS OF ONCOLOGY
- Single-Cell Transcriptomics Uncovers Glial Progenitor Diversity and Cell Fate Determinants during Development and Gliomagenesis
- (2019) Qinjie Weng et al. Cell Stem Cell
- PI3K/AKT/mTOR Pathway Alterations Promote Malignant Progression and Xenograft Formation in Oligodendroglial Tumors
- (2019) Kensuke Tateishi et al. CLINICAL CANCER RESEARCH
- Stem cell-associated heterogeneity in Glioblastoma results from intrinsic tumor plasticity shaped by the microenvironment
- (2019) Anne Dirkse et al. Nature Communications
- Comprehensive Integration of Single-Cell Data
- (2019) Tim Stuart et al. CELL
- An Integrative Model of Cellular States, Plasticity, and Genetics for Glioblastoma
- (2019) Cyril Neftel et al. CELL
- Metascape provides a biologist-oriented resource for the analysis of systems-level datasets
- (2019) Yingyao Zhou et al. Nature Communications
- Deconvolution of transcriptomes and miRNomes by independent component analysis provides insights into biological processes and clinical outcomes of melanoma patients
- (2019) Petr V. Nazarov et al. BMC Medical Genomics
- Patient-derived xenografts of central nervous system metastasis reveal expansion of aggressive minor clones
- (2019) Ben Yi Tew et al. NEURO-ONCOLOGY
- Comprehensive genomic profiling of glioblastoma tumors, BTICs, and xenografts reveals stability and adaptation to growth environments
- (2019) Yaoqing Shen et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Molecular Evolution of IDH Wild-Type Glioblastomas Treated With Standard of Care Affects Survival and Design of Precision Medicine Trials: A Report From the EORTC 1542 Study
- (2019) Kaspar Draaisma et al. JOURNAL OF CLINICAL ONCOLOGY
- Longitudinal molecular trajectories of diffuse glioma in adults
- (2019) Floris P. Barthel et al. NATURE
- IDH mutant lower grade (WHO Grades II/III) astrocytomas can be stratified for risk by CDKN2A, CDK4 and PDGFRA copy number alterations
- (2019) Rui Ryan Yang et al. BRAIN PATHOLOGY
- A Patient-Derived Glioblastoma Organoid Model and Biobank Recapitulates Inter- and Intra-tumoral Heterogeneity
- (2019) Fadi Jacob et al. CELL
- Genomic and Phenotypic Characterization of a Broad Panel of Patient-Derived Xenografts Reflects the Diversity of Glioblastoma
- (2019) Rachael A. Vaubel et al. CLINICAL CANCER RESEARCH
- Novel, improved grading system(s) for IDH-mutant astrocytic gliomas
- (2018) Mitsuaki Shirahata et al. ACTA NEUROPATHOLOGICA
- Snakemake—a scalable bioinformatics workflow engine
- (2018) Johannes Köster et al. BIOINFORMATICS
- OUP accepted manuscript
- (2018) BIOINFORMATICS
- Computational approach to discriminate human and mouse sequences in patient-derived tumour xenografts
- (2018) Maurizio Callari et al. BMC GENOMICS
- Epidermal Growth Factor Receptor Extracellular Domain Mutations in Glioblastoma Present Opportunities for Clinical Imaging and Therapeutic Development
- (2018) Zev A. Binder et al. CANCER CELL
- The Immune Landscape of Cancer
- (2018) Vésteinn Thorsson et al. IMMUNITY
- DNA methylation-based classification of central nervous system tumours
- (2018) David Capper et al. NATURE
- Integrating single-cell transcriptomic data across different conditions, technologies, and species
- (2018) Andrew Butler et al. NATURE BIOTECHNOLOGY
- Discordant inheritance of chromosomal and extrachromosomal DNA elements contributes to dynamic disease evolution in glioblastoma
- (2018) Ana C. deCarvalho et al. NATURE GENETICS
- Primary glioblastoma cells for precision medicine: a quantitative portrait of genomic (in)stability during the first 30 passages
- (2018) Sathishkumar Baskaran et al. NEURO-ONCOLOGY
- Glioma through the looking GLASS: molecular evolution of diffuse gliomas and the Glioma Longitudinal Analysis Consortium
- (2018) et al. NEURO-ONCOLOGY
- A Distinct DNA Methylation Shift in a Subset of Glioma CpG Island Methylator Phenotypes during Tumor Recurrence
- (2018) Camila Ferreira de Souza et al. Cell Reports
- Using PDX for Preclinical Cancer Drug Discovery: The Evolving Field
- (2018) Juliet Williams Journal of Clinical Medicine
- Pharmacogenomic landscape of patient-derived tumor cells informs precision oncology therapy
- (2018) Jin-Ku Lee et al. NATURE GENETICS
- The DNA methylation landscape of glioblastoma disease progression shows extensive heterogeneity in time and space
- (2018) Johanna Klughammer et al. NATURE MEDICINE
- A biobank of patient-derived pediatric brain tumor models
- (2018) Sebastian Brabetz et al. NATURE MEDICINE
- PDX Finder: A portal for patient-derived tumor xenograft model discovery
- (2018) Nathalie Conte et al. NUCLEIC ACIDS RESEARCH
- Dianhydrogalactitol induces replication-dependent DNA damage in tumor cells preferentially resolved by homologous recombination
- (2018) Beibei Zhai et al. Cell Death & Disease
- Lack of functional normalisation of tumour vessels following anti-angiogenic therapy in glioblastoma
- (2017) Nina Obad et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- Patient-derived xenografts undergo mouse-specific tumor evolution
- (2017) Uri Ben-David et al. NATURE GENETICS
- EGFR heterogeneity and implications for therapeutic intervention in glioblastoma
- (2017) Eskil Eskilsson et al. NEURO-ONCOLOGY
- ClinVar: improving access to variant interpretations and supporting evidence
- (2017) Melissa J Landrum et al. NUCLEIC ACIDS RESEARCH
- Single-Cell RNA-Seq Analysis of Infiltrating Neoplastic Cells at the Migrating Front of Human Glioblastoma
- (2017) Spyros Darmanis et al. Cell Reports
- The 2016 World Health Organization Classification of Tumors of the Central Nervous System: a summary
- (2016) David N. Louis et al. ACTA NEUROPATHOLOGICA
- A Three-Dimensional Organoid Culture System Derived from Human Glioblastomas Recapitulates the Hypoxic Gradients and Cancer Stem Cell Heterogeneity of Tumors Found In Vivo
- (2016) Christopher G. Hubert et al. CANCER RESEARCH
- Molecular Profiling Reveals Biologically Discrete Subsets and Pathways of Progression in Diffuse Glioma
- (2016) Michele Ceccarelli et al. CELL
- Clonal evolution of glioblastoma under therapy
- (2016) Jiguang Wang et al. NATURE GENETICS
- Association between DNA Methylation in Whole Blood and Measures of Glucose Metabolism: KORA F4 Study
- (2016) Jennifer Kriebel et al. PLoS One
- Molecular crosstalk between tumour and brain parenchyma instructs histopathological features in glioblastoma
- (2016) Sébastien Bougnaud et al. Oncotarget
- CNVkit: Genome-Wide Copy Number Detection and Visualization from Targeted DNA Sequencing
- (2016) Eric Talevich et al. PLoS Computational Biology
- Next-generation sequencing in routine brain tumor diagnostics enables an integrated diagnosis and identifies actionable targets
- (2015) Felix Sahm et al. ACTA NEUROPATHOLOGICA
- Manta: rapid detection of structural variants and indels for germline and cancer sequencing applications
- (2015) Xiaoyu Chen et al. BIOINFORMATICS
- Highly Parallel Genome-wide Expression Profiling of Individual Cells Using Nanoliter Droplets
- (2015) Evan Z. Macosko et al. CELL
- Whole-genome and multisector exome sequencing of primary and post-treatment glioblastoma reveals patterns of tumor evolution
- (2015) Hoon Kim et al. GENOME RESEARCH
- CDKN2ALoss Is Associated With Shortened Overall Survival in Lower-Grade (World Health Organization Grades II–III) Astrocytomas
- (2015) Gerald F. Reis et al. JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY
- High-throughput screening using patient-derived tumor xenografts to predict clinical trial drug response
- (2015) Hui Gao et al. NATURE MEDICINE
- Babelomics 5.0: functional interpretation for new generations of genomic data
- (2015) Roberto Alonso et al. NUCLEIC ACIDS RESEARCH
- EGFRAmplification and Glioblastoma Stem-Like Cells
- (2015) Katrin Liffers et al. Stem Cells International
- Targetable Signaling Pathway Mutations Are Associated with Malignant Phenotype in IDH-Mutant Gliomas
- (2014) H. Wakimoto et al. CLINICAL CANCER RESEARCH
- Dynamics of genomic clones in breast cancer patient xenografts at single-cell resolution
- (2014) Peter Eirew et al. NATURE
- PyClone: statistical inference of clonal population structure in cancer
- (2014) Andrew Roth et al. NATURE METHODS
- Single-cell RNA-seq highlights intratumoral heterogeneity in primary glioblastoma
- (2014) A. P. Patel et al. SCIENCE
- EGFR Variant Heterogeneity in Glioblastoma Resolved through Single-Nucleus Sequencing
- (2014) J. M. Francis et al. Cancer Discovery
- U-251 revisited: genetic drift and phenotypic consequences of long-term cultures of glioblastoma cells
- (2014) Anja Torsvik et al. Cancer Medicine
- EGFR wild-type amplification and activation promote invasion and development of glioblastoma independent of angiogenesis
- (2013) Krishna M. Talasila et al. ACTA NEUROPATHOLOGICA
- Glioblastomas are composed of genetically divergent clones with distinct tumourigenic potential and variable stem cell-associated phenotypes
- (2013) Daniel Stieber et al. ACTA NEUROPATHOLOGICA
- Side population in human glioblastoma is non-tumorigenic and characterizes brain endothelial cells
- (2013) Anna Golebiewska et al. BRAIN
- The Somatic Genomic Landscape of Glioblastoma
- (2013) Cameron W. Brennan et al. CELL
- The Cancer Genome Atlas Pan-Cancer analysis project
- (2013) John N Weinstein et al. NATURE GENETICS
- Spontaneous loss of heterozygosity leading to homozygous R132H in a patient-derived IDH1 mutant cell line
- (2013) H. A. Luchman et al. NEURO-ONCOLOGY
- Serum-free culture success of glial tumors is related to specific molecular profiles and expression of extracellular matrix–associated gene modules
- (2013) Rutger K. Balvers et al. NEURO-ONCOLOGY
- A Novel, Diffusely Infiltrative Xenograft Model of Human Anaplastic Oligodendroglioma with Mutations in FUBP1, CIC, and IDH1
- (2013) Barbara Klink et al. PLoS One
- Intratumor heterogeneity in human glioblastoma reflects cancer evolutionary dynamics
- (2013) A. Sottoriva et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Patient-Specific Orthotopic Glioblastoma Xenograft Models Recapitulate the Histopathology and Biology of Human Glioblastomas In Situ
- (2013) Kyeung Min Joo et al. Cell Reports
- Increased mitochondrial activity in a novel IDH1-R132H mutant human oligodendroglioma xenograft model: in situ detection of 2-HG and α-KG
- (2013) Anna C Navis et al. Acta Neuropathologica Communications
- A beta-mixture quantile normalization method for correcting probe design bias in Illumina Infinium 450 k DNA methylation data
- (2012) Andrew E. Teschendorff et al. BIOINFORMATICS
- A program for annotating and predicting the effects of single nucleotide polymorphisms, SnpEff
- (2012) Pablo Cingolani et al. FLY
- Intratumoral heterogeneity of receptor tyrosine kinases EGFR and PDGFRA amplification in glioblastoma defines subpopulations with distinct growth factor response
- (2012) N. J. Szerlip et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Glioblastoma-Derived Epidermal Growth Factor Receptor Carboxyl-Terminal Deletion Mutants Are Transforming and Are Sensitive to EGFR-Directed Therapies
- (2011) J. Cho et al. CANCER RESEARCH
- Heterogeneity Maintenance in Glioblastoma: A Social Network
- (2011) R. Bonavia et al. CANCER RESEARCH
- Tumor invasion after treatment of glioblastoma with bevacizumab: radiographic and pathologic correlation in humans and mice
- (2011) J. F. de Groot et al. NEURO-ONCOLOGY
- An in vivo patient-derived model of endogenous IDH1-mutant glioma
- (2011) H. A. Luchman et al. NEURO-ONCOLOGY
- Maintenance of primary tumor phenotype and genotype in glioblastoma stem cells
- (2011) H. Wakimoto et al. NEURO-ONCOLOGY
- Anti-VEGF treatment reduces blood supply and increases tumor cell invasion in glioblastoma
- (2011) Olivier Keunen et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A reproducible brain tumour model established from human glioblastoma biopsies
- (2010) Jian Wang et al. BMC CANCER
- Identification of a CpG Island Methylator Phenotype that Defines a Distinct Subgroup of Glioma
- (2010) Houtan Noushmehr et al. CANCER CELL
- Integrated Genomic Analysis Identifies Clinically Relevant Subtypes of Glioblastoma Characterized by Abnormalities in PDGFRA, IDH1, EGFR, and NF1
- (2010) Roel G.W. Verhaak et al. CANCER CELL
- Differentiation Therapy Exerts Antitumor Effects on Stem-like Glioma Cells
- (2010) B. Campos et al. CLINICAL CANCER RESEARCH
- Immunohistochemical Expression of Stem Cell, Endothelial Cell, and Chemosensitivity Markers in Primary Glioma Spheroids Cultured in Serum-Containing and Serum-Free Medium
- (2010) Karina Christensen et al. NEUROSURGERY
- The Sequence Alignment/Map format and SAMtools
- (2009) H. Li et al. BIOINFORMATICS
- Phenotypic and Genotypic Characterization of Orthotopic Human Glioma Models and Its Relevance for the Study of Anti-glioma Therapy
- (2008) An Claes et al. BRAIN PATHOLOGY
- A novel eGFP-expressing immunodeficient mouse model to study tumor-host interactions
- (2008) Simone P. Niclou et al. FASEB JOURNAL
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started