MIC26 and MIC27 cooperate to regulate cardiolipin levels and the landscape of OXPHOS complexes

Cristae undergo continuous cycles of membrane remodelling in a MICOS ‐dependent manner

(2020) Arun Kumar Kondadi et al.   EMBO REPORTS

Mutation in the MICOS subunit gene APOO (MIC26) associated with an X-linked recessive mitochondrial myopathy, lactic acidosis, cognitive impairment and autistic features

(2020) Cristiane Benincá et al.   JOURNAL OF MEDICAL GENETICS

Maintenance of Cardiolipin and Crista Structure Requires Cooperative Functions of Mitochondrial Dynamics and Phospholipid Transport

(2019) Rieko Kojima et al.   Cell Reports

Dimers of mitochondrial ATP synthase induce membrane curvature and self-assemble into rows

(2019) Thorsten B. Blum et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A MICOS-TIM22 Association Promotes Carrier Import into Human Mitochondria

(2019) Sylvie Callegari et al.   JOURNAL OF MOLECULAR BIOLOGY

Mic60 exhibits a coordinated clustered distribution along and across yeast and mammalian mitochondria

(2019) Stefan Stoldt et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Linking mitochondrial dynamics, cristae remodeling and supercomplex formation: How mitochondrial structure can regulate bioenergetics

(2019) Nicole Baker et al.   MITOCHONDRION

Mitochondrial cristae narrowing upon higher 2-oxoglutarate load

(2019) Andrea Dlasková et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Functional Interplay between Cristae Biogenesis, Mitochondrial Dynamics and Mitochondrial DNA Integrity

(2019) Arun Kumar Kondadi et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Individual cristae within the same mitochondrion display different membrane potentials and are functionally independent

(2019) Dane M Wolf et al.   EMBO JOURNAL

Who and how in the regulation of mitochondrial cristae shape and function

(2018) R. Quintana-Cabrera et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Cardiolipin synthesizing enzymes form a complex that interacts with cardiolipin-dependent membrane organizing proteins

(2018) Mauro Serricchio et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Assembly of the Mitochondrial Cristae Organizer Mic10 Is Regulated by Mic26–Mic27 Antagonism and Cardiolipin

(2018) Heike Rampelt et al.   JOURNAL OF MOLECULAR BIOLOGY

PINK1 Phosphorylates MIC60/Mitofilin to Control Structural Plasticity of Mitochondrial Crista Junctions

(2018) Pei-I Tsai et al.   MOLECULAR CELL

The cristae modulator Optic atrophy 1 requires mitochondrial ATP synthase oligomers to safeguard mitochondrial function

(2018) Rubén Quintana-Cabrera et al.   Nature Communications

The PRIDE database and related tools and resources in 2019: improving support for quantification data

(2018) Yasset Perez-Riverol et al.   NUCLEIC ACIDS RESEARCH

The short variant of the mitochondrial dynamin OPA1 maintains mitochondrial energetics and cristae structure

(2017) Hakjoo Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mic10, a Core Subunit of the Mitochondrial Contact Site and Cristae Organizing System, Interacts with the Dimeric F 1 F o -ATP Synthase

(2017) Heike Rampelt et al.   JOURNAL OF MOLECULAR BIOLOGY

INA complex liaises the F1Fo-ATP synthase membrane motor modules

(2017) Nataliia Naumenko et al.   Nature Communications

Mito-Morphosis: Mitochondrial Fusion, Fission, and Cristae Remodeling as Key Mediators of Cellular Function

(2016) Lena Pernas et al.   Annual Review of Physiology

Mitochondrial hepato-encephalopathy due to deficiency of QIL1/MIC13 (C19orf70), a MICOS complex subunit

(2016) Avraham Zeharia et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Hypoxic HepG2 cell adaptation decreases ATP synthase dimers and ATP production in inflated cristae by mitofilin down-regulation concomitant to MICOS clustering

(2016) Lydie Plecitá-Hlavatá et al.   FASEB JOURNAL

OPA1 functionally interacts with MIC60 but is dispensable for crista junction formation

(2016) Miguel Barrera et al.   FEBS LETTERS

MICOS and phospholipid transfer by Ups2–Mdm35 organize membrane lipid synthesis in mitochondria

(2016) Mari J. Aaltonen et al.   JOURNAL OF CELL BIOLOGY

OPA1 processing in cell death and disease – the long and short of it

(2016) Thomas MacVicar et al.   JOURNAL OF CELL SCIENCE

Distinct Roles of Mic12 and Mic27 in the Mitochondrial Contact Site and Cristae Organizing System

(2016) Ralf M. Zerbes et al.   JOURNAL OF MOLECULAR BIOLOGY

Mitochondrial Cristae: Where Beauty Meets Functionality

(2016) Sara Cogliati et al.   TRENDS IN BIOCHEMICAL SCIENCES

QIL1 mutation causes MICOS disassembly and early onset fatal mitochondrial encephalopathy with liver disease

(2016) Virginia Guarani et al.   eLife

Mic13 Is Essential for Formation of Crista Junctions in Mammalian Cells

(2016) Ruchika Anand et al.   PLoS One

Assembly of F1F0-ATP synthases

(2015) Thilo Rühle et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

The non-glycosylated isoform of MIC26 is a constituent of the mammalian MICOS complex and promotes formation of crista junctions

(2015) Sebastian Koob et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

MICOS coordinates with respiratory complexes and lipids to establish mitochondrial inner membrane architecture

(2015) Jonathan R Friedman et al.   eLife

QIL1 is a novel mitochondrial protein required for MICOS complex stability and cristae morphology

(2015) Virginia Guarani et al.   eLife

OPA1-dependent cristae modulation is essential for cellular adaptation to metabolic demand

(2014) D. A. Patten et al.   EMBO JOURNAL

The INA complex facilitates assembly of the peripheral stalk of the mitochondrial F1Fo-ATP synthase

(2014) O. Lytovchenko et al.   EMBO JOURNAL

Apolipoprotein O is mitochondrial and promotes lipotoxicity in heart

(2014) Annie Turkieh et al.   JOURNAL OF CLINICAL INVESTIGATION

Aim24 and MICOS modulate respiratory function, tafazzin-related cardiolipin modification and mitochondrial architecture

(2014) Max Emanuel Harner et al.   eLife

Mitochondrial Cristae Shape Determines Respiratory Chain Supercomplexes Assembly and Respiratory Efficiency

(2013) Sara Cogliati et al.   CELL

The connection between inner membrane topology and mitochondrial function

(2013) Carmen A. Mannella et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

APOOL Is a Cardiolipin-Binding Constituent of the Mitofilin/MINOS Protein Complex Determining Cristae Morphology in Mammalian Mitochondria

(2013) Tobias A. Weber et al.   PLoS One

STED super-resolution microscopy reveals an array of MINOS clusters along human mitochondria

(2013) D. C. Jans et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Supercomplex Assembly Determines Electron Flux in the Mitochondrial Electron Transport Chain

(2013) E. Lapuente-Brun et al.   SCIENCE

Proteolytic control of mitochondrial function and morphogenesis

(2012) Ruchika Anand et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Plasma apolipoprotein O level increased in the patients with acute coronary syndrome

(2012) Bi-lian Yu et al.   JOURNAL OF LIPID RESEARCH

Phosphatidylethanolamine and Cardiolipin Differentially Affect the Stability of Mitochondrial Respiratory Chain Supercomplexes

(2012) Lena Böttinger et al.   JOURNAL OF MOLECULAR BIOLOGY

Cardiolipin Affects the Supramolecular Organization of ATP Synthase in Mitochondria

(2011) Devrim Acehan et al.   BIOPHYSICAL JOURNAL

Dual Role of Mitofilin in Mitochondrial Membrane Organization and Protein Biogenesis

(2011) Karina von der Malsburg et al.   DEVELOPMENTAL CELL

The mitochondrial contact site complex, a determinant of mitochondrial architecture

(2011) Max Harner et al.   EMBO JOURNAL

A mitochondrial-focused genetic interaction map reveals a scaffold-like complex required for inner membrane organization in mitochondria

(2011) Suzanne Hoppins et al.   JOURNAL OF CELL BIOLOGY

During autophagy mitochondria elongate, are spared from degradation and sustain cell viability

(2011) Ligia C. Gomes et al.   NATURE CELL BIOLOGY

Macromolecular organization of ATP synthase and complex I in whole mitochondria

(2011) K. M. Davies et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural Diversity of Mitochondria

(2010) Carmen A. Mannella   Annals of the New York Academy of Sciences

Formation of cristae and crista junctions in mitochondria depends on antagonism between Fcj1 and Sue/g

(2009) Regina Rabl et al.   JOURNAL OF CELL BIOLOGY

Cristae formation—linking ultrastructure and function of mitochondria

(2008) Michael Zick et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Dimer ribbons of ATP synthase shape the inner mitochondrial membrane

(2008) Mike Strauss et al.   EMBO JOURNAL

Lipid extraction by methyl-tert-butyl ether for high-throughput lipidomics

(2008) Vitali Matyash et al.   JOURNAL OF LIPID RESEARCH