Anion-exchange chromatography mass spectrometry provides extensive coverage of primary metabolic pathways revealing altered metabolism in IDH1 mutant cells

Targeted Determination of Tissue Energy Status by LC-MS/MS

(2019) Xiaorong Fu et al.   ANALYTICAL CHEMISTRY

Biological Role and Therapeutic Potential of IDH Mutations in Cancer

(2018) Matthew S. Waitkus et al.   CANCER CELL

Improving metabolome coverage and data quality: advancing metabolomics and lipidomics for biomarker discovery

(2018) Dajana Vuckovic   CHEMICAL COMMUNICATIONS

Isocitrate dehydrogenase 1–mutated human gliomas depend on lactate and glutamate to alleviate metabolic stress

(2018) Krissie Lenting et al.   FASEB JOURNAL

MetaboAnalyst 4.0: towards more transparent and integrative metabolomics analysis

(2018) Jasmine Chong et al.   NUCLEIC ACIDS RESEARCH

Transaminase Inhibition by 2-Hydroxyglutarate Impairs Glutamate Biosynthesis and Redox Homeostasis in Glioma

(2018) Samuel K. McBrayer et al.   CELL

HMDB 4.0: the human metabolome database for 2018

(2017) David S Wishart et al.   NUCLEIC ACIDS RESEARCH

In silico gene expression analysis reveals glycolysis and acetate anaplerosis in IDH1 wild-type glioma and lactate and glutamate anaplerosis in IDH1-mutated glioma

(2017) Mohammed Khurshed et al.   Oncotarget

Use of Ion Chromatography/Mass Spectrometry for Targeted Metabolite Profiling of Polar Organic Acids

(2016) Chris Petucci et al.   ANALYTICAL CHEMISTRY

Expression of Idh1R132H in the Murine Subventricular Zone Stem Cell Niche Recapitulates Features of Early Gliomagenesis

(2016) Chiara Bardella et al.   CANCER CELL

Fundamentals of cancer metabolism

(2016) R. J. DeBerardinis et al.   Science Advances

Avoiding Misannotation of In-Source Fragmentation Products as Cellular Metabolites in Liquid Chromatography–Mass Spectrometry-Based Metabolomics

(2015) Yi-Fan Xu et al.   ANALYTICAL CHEMISTRY

Targeted Metabolomic Analysis of Head and Neck Cancer Cells Using High Performance Ion Chromatography Coupled with a Q Exactive HF Mass Spectrometer

(2015) Shen Hu et al.   ANALYTICAL CHEMISTRY

Metabolomic Profiling of Anionic Metabolites in Head and Neck Cancer Cells by Capillary Ion Chromatography with Orbitrap Mass Spectrometry

(2014) Junhua Wang et al.   ANALYTICAL CHEMISTRY

Method validation strategies involved in non-targeted metabolomics

(2014) Shama Naz et al.   JOURNAL OF CHROMATOGRAPHY A

What a difference a hydroxyl makes: mutant IDH, (R)-2-hydroxyglutarate, and cancer

(2013) J.-A. Losman et al.   GENES & DEVELOPMENT

Current practice of liquid chromatography–mass spectrometry in metabolomics and metabonomics

(2013) Helen G. Gika et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Cellular Metabolism and Disease: What Do Metabolic Outliers Teach Us?

(2012) Ralph J. DeBerardinis et al.   CELL

Web-based inference of biological patterns, functions and pathways from metabolomic data using MetaboAnalyst

(2011) Jianguo Xia et al.   Nature Protocols

Profiling the effects of isocitrate dehydrogenase 1 and 2 mutations on the cellular metabolome

(2011) Z. J. Reitman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hydrophobicity and Charge Shape Cellular Metabolite Concentrations

(2011) Arren Bar-Even et al.   PLoS Computational Biology

Isocitrate Dehydrogenase 1 Codon 132 Mutation Is an Important Prognostic Biomarker in Gliomas

(2009) Marc Sanson et al.   JOURNAL OF CLINICAL ONCOLOGY

Cancer-associated IDH1 mutations produce 2-hydroxyglutarate

(2009) Lenny Dang et al.   NATURE

Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation

(2009) M. G. Vander Heiden et al.   SCIENCE

Substrate specificity and structure of human aminoadipate aminotransferase/kynurenine aminotransferase II

(2008) Qian Han et al.   BIOSCIENCE REPORTS