Integrated multiomics analysis of hepatoblastoma unravels its heterogeneity and provides novel druggable targets

New insights into diagnosis and therapeutic options for proliferative hepatoblastoma

(2018) Katarzyna B. Hooks et al.   HEPATOLOGY

The landscape of genomic alterations across childhood cancers

(2018) Susanne N. Gröbner et al.   NATURE

Prognostic implication of NQO1 overexpression in hepatocellular carcinoma

(2017) Lijuan Lin et al.   HUMAN PATHOLOGY

Multilineage communication regulates human liver bud development from pluripotency

(2017) J. Gray Camp et al.   NATURE

Downregulation of NAD(P)H:quinone oxidoreductase 1 inhibits proliferation, cell cycle and migration of cholangiocarcinoma cells

(2017) Siriwoot Butsri et al.   Oncology Letters

The Children's Hepatic tumors International Collaboration (CHIC): Novel global rare tumor database yields new prognostic factors in hepatoblastoma and becomes a research model

(2016) Piotr Czauderna et al.   EUROPEAN JOURNAL OF CANCER

Genomic analysis of hepatoblastoma identifies distinct molecular and prognostic subgroups

(2016) Pavel Sumazin et al.   HEPATOLOGY

DNA methylation landscape of hepatoblastomas reveals arrest at early stages of liver differentiation and cancer-related alterations

(2016) Mariana Maschietto et al.   Oncotarget

LOLA: enrichment analysis for genomic region sets and regulatory elements in R and Bioconductor

(2015) Nathan C. Sheffield et al.   BIOINFORMATICS

A Phase I Trial of DFMO Targeting Polyamine Addiction in Patients with Relapsed/Refractory Neuroblastoma

(2015) Giselle L. Saulnier Sholler et al.   PLoS One

Genetic and epigenetic regulation of gene expression in fetal and adult human livers

(2014) Marc Bonder et al.   BMC GENOMICS

Exome sequencing of hepatoblastoma reveals novel mutations and cancer genes in the Wnt pathway and ubiquitin ligase complex

(2014) Deshui Jia et al.   HEPATOLOGY

The genomic landscape of hepatoblastoma and their progenies with HCC-like features

(2014) Melanie Eichenmüller et al.   JOURNAL OF HEPATOLOGY

The DDBJ Japanese Genotype-phenotype Archive for genetic and phenotypic human data

(2014) Yuichi Kodama et al.   NUCLEIC ACIDS RESEARCH

DFMO/eflornithine inhibits migration and invasion downstream of MYCN and involves p27Kip1 activity in neuroblastoma

(2013) DANA-LYNN T. KOOMOA et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Dose-dense cisplatin-based chemotherapy and surgery for children with high-risk hepatoblastoma (SIOPEL-4): a prospective, single-arm, feasibility study

(2013) József Zsiros et al.   LANCET ONCOLOGY

An empirical Bayesian framework for somatic mutation detection from cancer genome sequencing data

(2013) Yuichi Shiraishi et al.   NUCLEIC ACIDS RESEARCH

NAD(P)H:quinone oxidoreductase 1 (NQO1) in the sensitivity and resistance to antitumor quinones

(2011) David Siegel et al.   BIOCHEMICAL PHARMACOLOGY

Complete Surgical Resection Is Curative for Children With Hepatoblastoma With Pure Fetal Histology: A Report From the Children's Oncology Group

(2011) Marcio H. Malogolowkin et al.   JOURNAL OF CLINICAL ONCOLOGY

ConsensusClusterPlus: a class discovery tool with confidence assessments and item tracking

(2010) Matthew D. Wilkerson et al.   BIOINFORMATICS

Organogenesis and Development of the Liver

(2010) Karim Si-Tayeb et al.   DEVELOPMENTAL CELL

Identification ofptproas a novel target gene of Wnt signaling and its potential role as a receptor for Wnt

(2010) Minseong Kim et al.   FEBS LETTERS

Successful Treatment of Childhood High-Risk Hepatoblastoma With Dose-Intensive Multiagent Chemotherapy and Surgery: Final Results of the SIOPEL-3HR Study

(2010) József Zsíros et al.   JOURNAL OF CLINICAL ONCOLOGY

Outcome of hepatoblastomas treated using the Japanese Study Group for Pediatric Liver Tumor (JPLT) protocol-2: report from the JPLT

(2010) Tomoro Hishiki et al.   PEDIATRIC SURGERY INTERNATIONAL

Dicoumarol enhances doxorubicin-induced cytotoxicity in p53 wild-type urothelial cancer cells through p38 activation

(2009) Yoshiyuki Matsui et al.   BJU INTERNATIONAL

Telomerase modulates Wnt signalling by association with target gene chromatin

(2009) Jae-Il Park et al.   NATURE

Hepatic Stem-like Phenotype and Interplay of Wnt/β-Catenin and Myc Signaling in Aggressive Childhood Liver Cancer

(2008) Stefano Cairo et al.   CANCER CELL