Article
Plant Sciences
Ylenia Pieracci, Martina Vento, Luisa Pistelli, Tiziana Lombardi, Laura Pistelli
Summary: This study investigated the germplasm conservation of Artemisia caerulescens through in vitro culture. It found that the volatile fraction of both in vitro shoots and different organs of the wild plant contained significant amounts of polyphenols and exhibited antioxidant activity, with oxygenated monoterpenes being the main chemical class of compounds in the essential oils.
Article
Chemistry, Applied
Gilson Celso Albuquerque Chagas Junior, Nelson Rosa Ferreira, Maria Beatriz A. Gloria, Luiza Helena da Silva Martins, Alessandra Santos Lopes
Summary: The use of starters, specifically a mixture of Saccharomyces cerevisiae and Pichia kudriavzevii, during cocoa fermentation can shorten the fermentation time, improve cocoa quality, and reduce the levels of putrefactive amines. This study shows that the combination of these two yeast species is a promising option for cocoa fermentation in order to produce high-quality cocoa efficiently.
Article
Biochemistry & Molecular Biology
Gilson Celso Albuquerque Chagas Junior, Nelson Rosa Ferreira, Eloisa Helena de Aguiar Andrade, Lidiane Diniz do Nascimento, Francilia Campos de Siqueira, Alessandra Santos Lopes
Summary: This study identified the volatile compounds in fermented and dried cocoa beans using three different yeast inoculants. Among them, P. kudriavzevii showed a high capacity for forming desirable compounds in chocolate, providing cocoa producers with an excellent alternative.
Article
Environmental Sciences
Alina Barbulescu
Summary: This article investigates the aerosol optical depth (AOD) measurements taken in the Arabian Gulf using Terra MODIS satellite data. Through Principal Component Analysis (PCA) and clustering algorithms, the study found that both regional and temporal tendencies of AOD data were stable and well-fitted.
Article
Engineering, Environmental
Yupeng Jiang, Xinhui Fang, Ying Ni, Jianzhong Huo, Qian Wang, Yuanyuan Liu, Xinrui Wang, Bin Ding
Summary: In this study, a novel Gd-MOF material was synthesized and functionalized for highly efficient and selective detection of epileptic curing drugs and biomarkers. The composite materials showed good luminescence performance and were successfully applied for detection in real biological samples.
CHEMICAL ENGINEERING JOURNAL
(2024)
Review
Microbiology
Alexander S. F. Berry, Camila Farias Amorim, Corbett L. Berry, Camille M. Syrett, Elise D. English, Daniel P. Beiting
Summary: With the increasing accessibility to high-throughput sequencing technology, the bottleneck in biomedical research has shifted to data analysis. This study describes a modular framework for teaching bioinformatics using publicly available RNA sequencing data sets from infectious disease studies, focusing on host-parasite interactions. Lessons learned from adapting the course for virtual learners during the COVID-19 pandemic are highlighted.
Article
Food Science & Technology
Aleksander Siger, Pawel Gornas
Summary: The tocopherol and tocotrienol profiles were studied in 418 plant oil samples, representing 31 families, 82 species, and 5 cross-species. Tocotrienols dominated in 15 species, while tocopherols dominated in 67 species. Gamma-T accounted for almost half (49.3%) of the total tocochromanol content, while alpha-T constituted one quarter (25.0%), and other tocochromanols were minor constituents. The presence of characteristic tocochromanol profiles in oils was related to the taxonomic plant origin. This study also demonstrated that both monocotyledonous and dicotyledonous families can be rich in tocotrienols. The usefulness of statistical tools such as PCA and HCA for differentiating plant samples based on their tocochromanol profile was shown.
FOOD RESEARCH INTERNATIONAL
(2023)
Article
Chemistry, Analytical
Francisco dos Santos Panero, Oscar Smiderle, Joao S. Panero, Fernando S. D. V. Faria, Pedro dos S. Panero, Anselmo F. R. Rodriguez
Summary: In this study, near-infrared spectroscopy and chemometric techniques were used to develop classification models for different commercial sesame cultivars. The results showed that it was possible to perform genotyping and classification of sesame cultivars and strains based on the near-infrared spectra. The study highlights the potential of these methods for forensic, fast, and non-destructive authentication of intact sesame seeds.
Article
Food Science & Technology
Chaoran Xia, Qiyuan Tian, Lingyu Kong, Xiaoqian Sun, Jingjing Shi, Xiaoqun Zeng, Daodong Pan
Summary: This study found that Limosilactobacillus fermentum (L. fermentum) RC4 can degrade nitrite (NIT) through metabolite degradation in a new manner. Liquid chromatography-mass spectrometry analysis identified 11 metabolites, including mesaconate, 3-methylthiopropionic acid, and trans-aconitic acid, which showed efficient NIT degradation abilities.
Article
Biochemical Research Methods
Bruna de Falco, Laura Grauso, Alberto Fiore, Giuliano Bonanomi, Virginia Lanzotti
Summary: Aromatic plants from the Mediterranean region were analyzed for their metabolites profile, total phenol content, and antioxidant activity using GC-MS metabolomics and chemometrics. Carob showed the highest values of TPC and antioxidant activity, indicating its potential for food and industrial applications.
PHYTOCHEMICAL ANALYSIS
(2022)
Article
Environmental Sciences
Ajay Kumar Taloor, Anjali Bala, Pankaj Mehta
Summary: A study was conducted in the Jammu plains of India to examine the suitability of drinking water and study the influence of local lithology on groundwater chemistry. 50 groundwater samples were collected during the post-monsoon and pre-monsoon seasons. The samples were dominated by Mg-Ca-HCO3 and Ca-Mg-HCO3 types. The overall groundwater quality was assessed using the Pollution Index of Groundwater (PIG), which indicated that the groundwater was suitable for domestic use except for a few samples requiring conventional treatment. Multivariate statistical analysis revealed that rock-water interactions and weathering of carbonate-bearing rocks significantly control groundwater chemistry. Additionally, trace elements were analyzed to assess the human health risk in the study area.
Article
Chemistry, Applied
Carla de Fatima Alves Nonato, Cicera Janaine Camilo, Debora Odilia Duarte Leite, Mario Gustavo Lucio Albuquerque da Abrega, Jaime Ribeiro-Filho, Irwin Rose Alencar de Menezes, Josean Fechine Tavares, Jose Galberto Martins da Costa
Summary: This study compared the chemical composition and antioxidant potential of essential oils from the Lippia genus through chemometric analysis. The results showed that the essential oils exhibited significant antioxidant activity, with different compounds in Lippia alba being effective in various antioxidant methods. The findings highlight the importance of Lippia compounds for protecting against oxidative stress and their potential use in food preservation.
Article
Chemistry, Applied
Nur Cebi, Muhammet Arici, Osman Sagdic
Summary: This research utilized FTIR, Raman, and GC-MS techniques combined with chemometrics to authenticate the quality of Rosa damascena essential oil. These techniques proved to be reliable, rapid, accurate, and cost-effective for quality evaluation of the essential oil.
Article
Agricultural Engineering
Ylenia Pieracci, Flavia Fulvio, Valeria Isca, Luisa Pistelli, Laura Bassolino, Massimo Montanari, Anna Moschella, Guido Flamini, Roberta Paris
Summary: The inflorescences of Cannabis sativa L. are a valuable by-product of industrial hemp cultivation, and the volatile fraction of these inflorescences has attracted attention for its applications in various fields. This study investigated the effect of phenological stage on the chemical composition and hydro-distillation yield of hemp-derived essential oil (EO). Two hemp varieties, Codimono (monoecious) and Fibrante (dioecious), were cultivated, and the flowering tops were collected at different stages. Analysis of the EO revealed that terpenes and phyto-cannabinoids were the major chemical classes, with sesquiterpene hydrocarbons being the most abundant components. The EO yield increased with phenological development, reaching its highest rate at seed harvest time.
INDUSTRIAL CROPS AND PRODUCTS
(2023)
Article
Spectroscopy
Celine Burnier, Virginie Favre, Genevieve Massonnet
Summary: This study aimed to optimize the parameters for polydimethylsiloxane (PDMS) analysis and detection by looking at resolution and number of scans. Experimental parameters were refined through a full factorial experimental design (FFD) and extended to a face centered central composite design (FCCD) for optimization. Repeatability of the results was investigated using principal component analysis (PCA) and hierarchical cluster analysis (HCA) to select the most relevant analytical parameters.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2021)
Article
Chemistry, Organic
Fan Zhang, Thomas P. Wyche, Yanlong Zhu, Doug R. Braun, Jia-Xuan Yan, Shaurya Chanana, Ying Ge, Ilia A. Guzei, Marc G. Chevrette, Cameron R. Currie, Michael G. Thomas, Scott R. Rajski, Tim S. Bugni
Article
Chemistry, Medicinal
Chris S. Thomas, Doug R. Braun, Jose Luis Olmos, Scott R. Rajski, George N. Phillips, David Andes, Tim S. Bugni
Article
Biochemistry & Molecular Biology
Vladimir Vinnik, Fan Zhang, Hyunjun Park, Taylor B. Cook, Kurt Throckmorton, Brian F. Pfleger, Tim S. Bugni, Michael G. Thomas
Summary: Siderophores are iron-chelating molecules produced by microorganisms and plants to acquire iron from the environment. A study on siderophore analogs from Agrobacterium fabrum strain C58 reveals unique molecular structures and substrate specificities, suggesting elaborate biosynthetic pathways in siderophore production. The presence of a distinct moiety in the analogs provides evidence for a potential mechanism involving L-DOPA in the formation of siderophores. Additionally, bioinformatic analyses indicate a wide distribution of siderophore-related molecules in various bacterial groups.
ACS CHEMICAL BIOLOGY
(2021)
Article
Multidisciplinary Sciences
Fan Zhang, Miao Zhao, Doug R. Braun, Spencer S. Ericksen, Jeff S. Piotrowski, Justin Nelson, Jian Peng, Gene E. Ananiev, Shaurya Chanana, Kenneth Barns, Jen Fossen, Hiram Sanchez, Marc G. Chevrette, Ilia A. Guzei, Changgui Zhao, Le Guo, Weiping Tang, Cameron R. Currie, Scott R. Rajski, Anjon Audhya, David R. Andes, Tim S. Bugni
Article
Medicine, Research & Experimental
Miao Zhao, Fan Zhang, Robert Zarnowski, Kenneth Barns, Ryley Jones, Jen Fossen, Hiram Sanchez, Scott R. Rajski, Anjon Audhya, Tim S. Bugni, David R. Andes
Summary: Turbinmicin is a broad-spectrum antifungal agent that targets biofilm growth. By disrupting extracellular vesicle delivery, turbinmicin impairs biofilm matrix assembly, making drug-resistant biofilms more susceptible to its fungicidal effects. Additionally, turbinmicin can potentiate the activity of other antifungal drugs.
JOURNAL OF CLINICAL INVESTIGATION
(2021)
Article
Biochemistry & Molecular Biology
Michelle A. Schorn, Stefan Verhoeven, Lars Ridder, Florian Huber, Deepa D. Acharya, Alexander A. Aksenov, Gajender Aleti, Jamshid Amiri Moghaddam, Allegra T. Aron, Saefuddin Aziz, Anelize Bauermeister, Katherine D. Bauman, Martin Baunach, Christine Beemelmanns, J. Michael Beman, Maria Victoria Berlanga-Clavero, Alex A. Blacutt, Helge B. Bode, Anne Boullie, Asker Brejnrod, Tim S. Bugni, Alexandra Calteau, Liu Cao, Victor J. Carrion, Raquel Castelo-Branco, Shaurya Chanana, Alexander B. Chase, Marc G. Chevrette, Leticia V. Costa-Lotufo, Jason M. Crawford, Cameron R. Currie, Bart Cuypers, Tam Dang, Tristan de Rond, Alyssa M. Demko, Elke Dittmann, Chao Du, Christopher Drozd, Jean-Claude Dujardin, Rachel J. Dutton, Anna Edlund, David P. Fewer, Neha Garg, Julia M. Gauglitz, Emily C. Gentry, Lena Gerwick, Evgenia Glukhov, Harald Gross, Muriel Gugger, Dulce G. Guillen Matus, Eric J. N. Helfrich, Benjamin-Florian Hempel, Jae-Seoun Hur, Marianna Iorio, Paul R. Jensen, Kyo Bin Kang, Leonard Kaysser, Neil L. Kelleher, Chung Sub Kim, Ki Hyun Kim, Irina Koester, Gabriele M. Koenig, Tiago Leao, Seoung Rak Lee, Yi-Yuan Lee, Xuanji Li, Jessica C. Little, Katherine N. Maloney, Daniel Maennle, Christian Martin H., Andrew C. McAvoy, Willam W. Metcalf, Hosein Mohimani, Carlos Molina-Santiago, Bradley S. Moore, Michael W. Mullowney, Mitchell Muskat, Louis-Felix Nothias, Ellis C. O'Neill, Elizabeth I. Parkinson, Daniel Petras, Jorn Piel, Emily C. Pierce, Karine Pires, Raphael Reher, Diego Romero, M. Caroline Roper, Michael Rust, Hamada Saad, Carmen Saenz, Laura M. Sanchez, Soren Johannes Sorensen, Margherita Sosio, Roderich D. Sussmuth, Douglas Sweeney, Kapil Tahlan, Regan J. Thomson, Nicholas J. Tobias, Amaro E. Trindade-Silva, Gilles P. van Wezel, Mingxun Wang, Kelly C. Weldon, Fan Zhang, Nadine Ziemert, Katherine R. Duncan, Max Cruesemann, Simon Rogers, Pieter C. Dorrestein, Marnix H. Medema, Justin J. J. van der Hooft
Summary: Genomics and metabolomics are commonly used to explore the diversity of specialized metabolites. The Paired Omics Data Platform aims to systematically document the connections between metabolome and (meta)genome data to aid in the identification of natural product biosynthetic origins and metabolite structures.
NATURE CHEMICAL BIOLOGY
(2021)
Article
Chemistry, Medicinal
Jia-Xuan Yan, Qihao Wu, Eric J. N. Helfrich, Marc G. Chevrette, Doug R. Braun, Heino Heyman, Gene E. Ananiev, Scott R. Rajski, Cameron R. Currie, Jon Clardy, Tim S. Bugni
Summary: Chemical investigations of a marine sponge-associated Bacillus led to the discovery of six new imidazolium-containing compounds. Their structures were elucidated and a plausible biosynthetic pathway was proposed. Among these compounds, only one displayed antibacterial activity.
Article
Chemistry, Organic
Fan Zhang, Rene F. Ramos Alvarenga, Kurt Throckmorton, Shaurya Chanana, Doug R. Braun, Jen Fossen, Miao Zhao, Sue McCrone, Mary Kay Harper, Scott R. Rajski, Warren E. Rose, David R. Andes, Michael G. Thomas, Tim S. Bugni
Summary: In this study, a novel marine-derived siderophore, Pseudonochelin (1), was discovered using genome mining and metabolomics technologies. It was found that 1 contained a previously unidentified 5-aminosalicylic acid unit. Through annotation of a putative biosynthetic gene cluster and bioinformatics analysis, the biosynthesis of 1 was proposed. Furthermore, 1 exhibited iron-dependent antibacterial activity both in vitro and in vivo.
Article
Microbiology
Shaurya Chanana, Doug R. Braun, Scott R. Rajski, Tim S. Bugni
MICROBIOLOGY RESOURCE ANNOUNCEMENTS
(2020)