Patient ancestry significantly contributes to molecular heterogeneity of systemic lupus erythematosus

Dissecting racial disparities in multiple myeloma

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Dissecting racial disparities in multiple myeloma—clues from differential immunoglobulin levels

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Association between changes in gene signatures expression and disease activity among patients with systemic lupus erythematosus

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The Missing Diversity in Human Genetic Studies

(2019) Giorgio Sirugo et al.   CELL

Genomic Identification of Low-Density Granulocytes and Analysis of Their Role in the Pathogenesis of Systemic Lupus Erythematosus

(2019) Brian J. Kegerreis et al.   JOURNAL OF IMMUNOLOGY

Disease severity is linked to an increase in autoantibody diversity in IgG4‐related disease

(2019) Hang Liu et al.   Arthritis & Rheumatology

Selective Histone Deacetylase 6 Inhibition Normalizes B Cell Activation and Germinal Center Formation in a Model of Systemic Lupus Erythematosus

(2019) Jingjing Ren et al.   Frontiers in Immunology

HLAand autoantibodies define scleroderma subtypes and risk in African and European Americans and suggest a role for molecular mimicry

(2019) Pravitt Gourh et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Progression of whole-blood transcriptional signatures from interferon-induced to neutrophil-associated patterns in severe influenza

(2018) Jake Dunning et al.   NATURE IMMUNOLOGY

The Representation of Gender and Race/Ethnic Groups in Randomized Clinical Trials of Individuals with Systemic Lupus Erythematosus

(2018) Titilola Falasinnu et al.   Current Rheumatology Reports

Genetic fine mapping of systemic lupus erythematosus MHC associations in Europeans and African Americans

(2018) Ken B Hanscombe et al.   HUMAN MOLECULAR GENETICS

Up-Regulation of TLR7-Mediated IFN-α Production by Plasmacytoid Dendritic Cells in Patients With Systemic Lupus Erythematosus

(2018) Kei Sakata et al.   Frontiers in Immunology

Identification of alterations in macrophage activation associated with disease activity in systemic lupus erythematosus

(2018) Adam C. Labonte et al.   PLoS One

Gene Expression and Pharmacodynamic Changes in 1,760 Systemic Lupus Erythematosus Patients From Two Phase III Trials of BAFF Blockade With Tabalumab

(2017) Robert W. Hoffman et al.   Arthritis & Rheumatology

Genetic Ancestry and Natural Selection Drive Population Differences in Immune Responses to Pathogens

(2016) Yohann Nédélec et al.   CELL

Personalized Immunomonitoring Uncovers Molecular Networks that Stratify Lupus Patients

(2016) Romain Banchereau et al.   CELL

Oxidized mitochondrial nucleoids released by neutrophils drive type I interferon production in human lupus

(2016) Simone Caielli et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Race-related differences in antibody responses to the inactivated influenza vaccine are linked to distinct pre-vaccination gene expression profiles in blood

(2016) Raj Kurupati et al.   Oncotarget

Efficacy and safety of subcutaneous tabalumab, a monoclonal antibody to B-cell activating factor, in patients with systemic lupus erythematosus: results from ILLUMINATE-2, a 52-week, phase III, multicentre, randomised, double-blind, placebo-controlled study

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Efficacy and safety of subcutaneous tabalumab in patients with systemic lupus erythematosus: results from ILLUMINATE-1, a 52-week, phase III, multicentre, randomised, double-blind, placebo-controlled study

(2015) D A Isenberg et al.   ANNALS OF THE RHEUMATIC DISEASES

limma powers differential expression analyses for RNA-sequencing and microarray studies

(2015) Matthew E. Ritchie et al.   NUCLEIC ACIDS RESEARCH

Ethnicity-specific epigenetic variation in naïve CD4+ T cells and the susceptibility to autoimmunity

(2015) Patrick Coit et al.   Epigenetics & Chromatin

The contribution of natural selection to present-day susceptibility to chronic inflammatory and autoimmune disease

(2014) Jessica F Brinkworth et al.   CURRENT OPINION IN IMMUNOLOGY

MHC associations with clinical and autoantibody manifestations in European SLE

(2014) D L Morris et al.   GENES AND IMMUNITY

Type I Interferon in the Pathogenesis of Lupus

(2014) M. K. Crow   JOURNAL OF IMMUNOLOGY

Associations between race, sex and immune response variations to rubella vaccination in two independent cohorts

(2014) Iana H. Haralambieva et al.   VACCINE

Prevalence and Incidence of Systemic Lupus Erythematosus in a Population-Based Registry of American Indian and Alaska Native People, 2007-2009

(2014) Elizabeth D. Ferucci et al.   Arthritis & Rheumatology

GSVA: gene set variation analysis for microarray and RNA-Seq data

(2013) Sonja Hänzelmann et al.   BMC BIOINFORMATICS

Blood-Informative Transcripts Define Nine Common Axes of Peripheral Blood Gene Expression

(2013) Marcela Preininger et al.   PLoS Genetics

The Incidence and Prevalence of Systemic Lupus Erythematosus, 2002-2004: The Georgia Lupus Registry

(2013) S. Sam Lim et al.   Arthritis & Rheumatology

Population-Based Incidence and Prevalence of Systemic Lupus Erythematosus: The Michigan Lupus Epidemiology and Surveillance Program

(2013) Emily C. Somers et al.   Arthritis & Rheumatology

Activation of the Interferon Pathway is Dependent Upon Autoantibodies in African-American SLE Patients, but Not in European-American SLE Patients

(2013) Kichul Ko et al.   Frontiers in Immunology

Differences between Male and Female Systemic Lupus Erythematosus in a Multiethnic Population

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Autoantibodies associated with RNA are more enriched than anti-dsDNA antibodies in circulating immune complexes in SLE

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Two Major Autoantibody Clusters in Systemic Lupus Erythematosus

(2012) Kathryn H. Ching et al.   PLoS One

Mycophenolic acid counteracts B cell proliferation and plasmablast formation in patients with systemic lupus erythematosus

(2012) Sebastian Eickenberg et al.   ARTHRITIS RESEARCH & THERAPY

Hydroxychloroquine is associated with impaired interferon-alpha and tumor necrosis factor-alpha production by plasmacytoid dendritic cells in systemic lupus erythematosus

(2012) Karim Sacre et al.   ARTHRITIS RESEARCH & THERAPY

Influenza vaccination responses in human systemic lupus erythematosus: Impact of clinical and demographic features

(2011) Sherry R. Crowe et al.   ARTHRITIS AND RHEUMATISM

B lymphocyte stimulator levels in systemic lupus erythematosus: Higher circulating levels in African American patients and increased production after influenza vaccination in patients with low baseline levels

(2011) Lauren L. Ritterhouse et al.   ARTHRITIS AND RHEUMATISM

A phase III, randomized, placebo-controlled study of belimumab, a monoclonal antibody that inhibits B lymphocyte stimulator, in patients with systemic lupus erythematosus

(2011) Richard Furie et al.   ARTHRITIS AND RHEUMATISM

Mycophenolic Acid Differentially Impacts B Cell Function Depending on the Stage of Differentiation

(2011) J. L. Karnell et al.   JOURNAL OF IMMUNOLOGY

Netting Neutrophils Induce Endothelial Damage, Infiltrate Tissues, and Expose Immunostimulatory Molecules in Systemic Lupus Erythematosus

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Efficacy and safety of belimumab in patients with active systemic lupus erythematosus: a randomised, placebo-controlled, phase 3 trial

(2011) Sandra V Navarra et al.   LANCET

The role of antimalarial agents in the treatment of SLE and lupus nephritis

(2011) Senq-J Lee et al.   Nature Reviews Nephrology

Netting Neutrophils Are Major Inducers of Type I IFN Production in Pediatric Systemic Lupus Erythematosus

(2011) G. S. Garcia-Romo et al.   Science Translational Medicine

Network analysis of associations between serum interferon-α activity, autoantibodies, and clinical features in systemic lupus erythematosus

(2010) Corinna E. Weckerle et al.   ARTHRITIS AND RHEUMATISM

A Distinct Subset of Proinflammatory Neutrophils Isolated from Patients with Systemic Lupus Erythematosus Induces Vascular Damage and Synthesizes Type I IFNs

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Epidemiology of systemic lupus erythematosus in Asia

(2010) E. Osio-Salido et al.   LUPUS

Trait-stratified genome-wide association study identifies novel and diverse genetic associations with serologic and cytokine phenotypes in systemic lupus erythematosus

(2010) Silvia N Kariuki et al.   ARTHRITIS RESEARCH & THERAPY

Efficacy and safety of rituximab in moderately-to-severely active systemic lupus erythematosus: The randomized, double-blind, phase ii/iii systemic lupus erythematosus evaluation of rituximab trial

(2009) Joan T. Merrill et al.   ARTHRITIS AND RHEUMATISM

Interferon signature gene expression is correlated with autoantibody profiles in patients with incomplete lupus syndromes

(2009) Q.-Z. Li et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Reduced Neutrophil Count in People of African Descent Is Due To a Regulatory Variant in the Duffy Antigen Receptor for Chemokines Gene

(2009) David Reich et al.   PLoS Genetics

WGCNA: an R package for weighted correlation network analysis

(2008) Peter Langfelder et al.   BMC BIOINFORMATICS

Dysfunctional interferon-α production by peripheral plasmacytoid dendritic cells upon Toll-like receptor-9 stimulation in patients with systemic lupus erythematosus

(2008) Seung-Ki Kwok et al.   ARTHRITIS RESEARCH & THERAPY