Andrographis paniculata Extract Relieves Pain and Inflammation in Monosodium Iodoacetate-Induced Osteoarthritis and Acetic Acid-Induced Writhing in Animal Models

Inhibition of MMPs and ADAM/ADAMTS

(2019) Charles J. Malemud   BIOCHEMICAL PHARMACOLOGY

A double‐blind, randomized, placebo‐controlled study to assess the efficacy of Andrographis paniculata standardized extract (ParActin®) on pain reduction in subjects with knee osteoarthritis

(2019) Juan L. Hancke et al.   PHYTOTHERAPY RESEARCH

The Pharmacology of Pain Associated With the Monoiodoacetate Model of Osteoarthritis

(2019) João de Sousa Valente   Frontiers in Pharmacology

Ficus deltoidea Prevented Bone Loss in Preclinical Osteoporosis/Osteoarthritis Model by Suppressing Inflammation

(2018) Nur Adeelah Che Ahmad Tantowi et al.   CALCIFIED TISSUE INTERNATIONAL

Evaluation of the novel avocado/soybean unsaponifiable Arthrocen to alter joint pain and inflammation in a rat model of osteoarthritis

(2018) Ramin Goudarzi et al.   PLoS One

Avocado soybean unsaponifiables ameliorates cartilage and subchondral bone degeneration in mono-iodoacetate-induced knee osteoarthritis in rats

(2018) Aliaa S.A. Al-Afify et al.   TISSUE & CELL

Peripheral Mechanisms Contributing to Osteoarthritis Pain

(2018) Delfien Syx et al.   Current Rheumatology Reports

Andrographis paniculata diterpenoids and ethanolic extract inhibit TNFα-induced ICAM-1 expression in EA.hy926 cells

(2018) Hung-Chih Lin et al.   PHYTOMEDICINE

Andrographolide Benefits Rheumatoid Arthritis via Inhibiting MAPK Pathways

(2017) Zun-zhong Li et al.   INFLAMMATION

Herb-drug interaction of Andrographis paniculata (Nees) extract and andrographolide on pharmacokinetic and pharmacodynamic of naproxen in rats

(2017) Aishwarya Balap et al.   JOURNAL OF ETHNOPHARMACOLOGY

Mori Folium water extract alleviates articular cartilage damages and inflammatory responses in monosodium iodoacetate-induced osteoarthritis rats

(2017) Jin-Woo Jeong et al.   Molecular Medicine Reports

Andrographis paniculata (Chuān Xīn Lián) for symptomatic relief of acute respiratory tract infections in adults and children: A systematic review and meta-analysis

(2017) Xiao-Yang Hu et al.   PLoS One

Inhibitory effects of andrographolide on activated macrophages and adjuvant-induced arthritis

(2017) Swati Gupta et al.   INFLAMMOPHARMACOLOGY

Anti-inflammatory effects of ursodeoxycholic acid by lipopolysaccharide-stimulated inflammatory responses in RAW 264.7 macrophages

(2017) Wan-Kyu Ko et al.   PLoS One

Cartilage damage and bone erosion are more prominent determinants of functional impairment in longstanding experimental arthritis than synovial inflammation

(2016) Silvia Hayer et al.   Disease Models & Mechanisms

Andrographis Paniculata shows anti-nociceptive effects in an animal model of sensory hypersensitivity associated with migraine

(2016) Rosaria Greco   FUNCTIONAL NEUROLOGY

Osteoarthritis and all-cause mortality in worldwide populations: grading the evidence from a meta-analysis

(2016) Dan Xing et al.   Scientific Reports

Osteoarthritis pain

(2015) Serge Perrot   BEST PRACTICE & RESEARCH IN CLINICAL RHEUMATOLOGY

An in vitro study of anti-inflammatory activity of standardised Andrographis paniculata extracts and pure andrographolide

(2015) Mitchell Low et al.   BMC Complementary and Alternative Medicine

The Role of Changes in Extracellular Matrix of Cartilage in the Presence of Inflammation on the Pathology of Osteoarthritis

(2013) Maricela Maldonado et al.   Biomed Research International

Inflammation in osteoarthritis

(2011) Mary B. Goldring et al.   CURRENT OPINION IN RHEUMATOLOGY

Grape seed proanthocyanidin extract ameliorates monosodium iodoacetate-induced osteoarthritis

(2011) Yun Ju Woo et al.   EXPERIMENTAL AND MOLECULAR MEDICINE

Study of anti-inflammatory activities of the pure compounds from Andrographis paniculata (burm.f.) Nees and their effects on gene expression

(2010) Warisara Parichatikanond et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Anti-inflammatory Activity of New Compounds from Andrographis paniculata by NF-κB Transactivation Inhibition

(2010) Wen-Wan Chao et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

The analgesic and anti-inflammatory effect of WIN-34B, a new herbal formula for osteoarthritis composed of Lonicera japonica Thunb and Anemarrhena asphodeloides BUNGE in vivo

(2010) Moonkyu Kang et al.   JOURNAL OF ETHNOPHARMACOLOGY

Effect of an extract of Andrographis paniculata leaves on inflammatory and allergic mediators in vitro

(2010) C.V. Chandrasekaran et al.   JOURNAL OF ETHNOPHARMACOLOGY

Isolation and identification of bioactive compounds in Andrographis paniculata (Chuanxinlian)

(2010) Wen-Wan Chao et al.   Chinese Medicine

Analgesic, antipyretic, anti-inflammatory and toxic effects of andrographolide derivatives in experimental animals

(2009) Supawadee Suebsasana et al.   ARCHIVES OF PHARMACAL RESEARCH

Mitochondrial DNA damage is involved in apoptosis caused by pro-inflammatory cytokines in human OA chondrocytes

(2009) J. Kim et al.   OSTEOARTHRITIS AND CARTILAGE

Andrographolide reduces IL-2 production in T-cells by interfering with NFAT and MAPK activation

(2008) María D. Carretta et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

The effect of hyaluronic acid on IL-1β-induced chondrocyte apoptosis in a rat model of osteoarthritis

(2008) Pang-Hu Zhou et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Identification of opticin, a member of the small leucine-rich repeat proteoglycan family, in human articular tissues: a novel target for MMP-13 in osteoarthritis

(2008) J. Monfort et al.   OSTEOARTHRITIS AND CARTILAGE

The contribution of the synovium, synovial derived inflammatory cytokines and neuropeptides to the pathogenesis of osteoarthritis

(2007) Saski Sutton et al.   VETERINARY JOURNAL