Heme-Dependent ER Stress Apoptosis: A Mechanism for the Selective Toxicity of the Dihydroartemisinin, NSC735847, in Colorectal Cancer Cells
出版年份 2020 全文链接
标题
Heme-Dependent ER Stress Apoptosis: A Mechanism for the Selective Toxicity of the Dihydroartemisinin, NSC735847, in Colorectal Cancer Cells
作者
关键词
-
出版物
Frontiers in Oncology
Volume 10, Issue -, Pages -
出版商
Frontiers Media SA
发表日期
2020-06-17
DOI
10.3389/fonc.2020.00965
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Cancer statistics, 2019
- (2019) Rebecca L. Siegel et al. CA-A CANCER JOURNAL FOR CLINICIANS
- Prostaglandin D2-ethanolamide induces skin cancer apoptosis by suppressing the activity of cellular antioxidants
- (2019) Ahmed E.M. Elhassanny et al. PROSTAGLANDINS & OTHER LIPID MEDIATORS
- Clinicopathologic and Racial/Ethnic Differences of Colorectal Cancer Among Adolescents and Young Adults
- (2019) Andreana N. Holowatyj et al. Clinical and Translational Gastroenterology
- Artesunate shows potent anti-tumor activity in B-cell lymphoma
- (2018) Thea Kristin Våtsveen et al. Journal of Hematology & Oncology
- Efficacy and safety of artemisinin-based combination therapy, and molecular markers for artemisinin and piperaquine resistance in Mainland Tanzania
- (2018) Mwaka A. Kakolwa et al. MALARIA JOURNAL
- Heme Induces Endoplasmic Reticulum Stress (HIER Stress) in Human Aortic Smooth Muscle Cells
- (2018) Tamás Gáll et al. Frontiers in Physiology
- Lifestyle-Related Factors in the Self-Management of Chemotherapy-Induced Peripheral Neuropathy in Colorectal Cancer: A Systematic Review
- (2017) Tess M. E. Derksen et al. Evidence-based Complementary and Alternative Medicine
- Artemisinin as an anticancer drug: Recent advances in target profiling and mechanisms of action
- (2017) Yin Kwan Wong et al. MEDICINAL RESEARCH REVIEWS
- Synthesis and Evaluation of the Novel Prostamide, 15-Deoxy, Δ 12,14 -Prostamide J 2 , as a Selective Antitumor Therapeutic
- (2017) Daniel A. Ladin et al. MOLECULAR CANCER THERAPEUTICS
- From ancient herb to modern drug: Artemisia annua and artemisinin for cancer therapy
- (2017) Thomas Efferth SEMINARS IN CANCER BIOLOGY
- Combination therapy in combating cancer
- (2017) Reza Bayat Mokhtari et al. Oncotarget
- Pathophysiology of Chemotherapy-Induced Peripheral Neuropathy
- (2017) Hana Starobova et al. Frontiers in Molecular Neuroscience
- Trial watch: Immunogenic cell death induction by anticancer chemotherapeutics
- (2017) Abhishek D. Garg et al. OncoImmunology
- Mechanistic Investigation of the Specific Anticancer Property of Artemisinin and Its Combination with Aminolevulinic Acid for Enhanced Anticolorectal Cancer Activity
- (2017) Jigang Wang et al. ACS Central Science
- Anticancer activity of a novel small molecule tubulin inhibitor STK899704
- (2017) Krisada Sakchaisri et al. PLoS One
- Profiling of Multiple Targets of Artemisinin Activated by Hemin in Cancer Cell Proteome
- (2016) Yiqing Zhou et al. ACS Chemical Biology
- Mechanism-Guided Design and Synthesis of a Mitochondria-Targeting Artemisinin Analogue with Enhanced Anticancer Activity
- (2016) Chong-Jing Zhang et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Compounds Triggering ER Stress Exert Anti-Melanoma Effects and Overcome BRAF Inhibitor Resistance
- (2016) Michaël Cerezo et al. CANCER CELL
- Artemisinin-Derived Dimers: Potent Antimalarial and Anticancer Agents
- (2016) Tony Fröhlich et al. JOURNAL OF MEDICINAL CHEMISTRY
- Clinical and non-clinical safety of artemisinin derivatives in pregnancy
- (2016) Caroline Gomes et al. REPRODUCTIVE TOXICOLOGY
- Dihydroartemisinin-Induced Apoptosis is Associated with Inhibition of Sarco/Endoplasmic Reticulum Calcium ATPase Activity in Colorectal Cancer
- (2015) Min Lu et al. CELL BIOCHEMISTRY AND BIOPHYSICS
- Monitoring of efficacy and safety of artemisinin-based anti-malarials for treatment of uncomplicated malaria: a review of evidence of implementation of anti-malarial therapeutic efficacy trials in Tanzania
- (2015) Alex Shayo et al. MALARIA JOURNAL
- Anandamide-induced endoplasmic reticulum stress and apoptosis are mediated by oxidative stress in non-melanoma skin cancer: Receptor-independent endocannabinoid signaling
- (2015) Eman Soliman et al. MOLECULAR CARCINOGENESIS
- Colorectal cancer
- (2015) Ernst J. Kuipers et al. Nature Reviews Disease Primers
- A Randomised, Double Blind, Placebo-Controlled Pilot Study of Oral Artesunate Therapy for Colorectal Cancer
- (2015) Sanjeev Krishna et al. EBioMedicine
- Endoplasmic reticulum stress associated responses in cancer
- (2014) Wen-An Wang et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Endoplasmic Reticulum Stress in Malignancy
- (2014) Hanna J. Clarke et al. CANCER CELL
- Efficacy and safety of artemisinin combination therapy (ACT) for non-falciparum malaria: a systematic review
- (2014) Benjamin J Visser et al. MALARIA JOURNAL
- Management of advanced colorectal cancer, part 1
- (2013) R. J. Cersosimo AMERICAN JOURNAL OF HEALTH-SYSTEM PHARMACY
- ER stress-induced cell death mechanisms
- (2013) Renata Sano et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Discovery of 7-Methyl-5-(1-{[3-(trifluoromethyl)phenyl]acetyl}-2,3-dihydro-1H-indol-5-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine (GSK2606414), a Potent and Selective First-in-Class Inhibitor of Protein Kinase R (PKR)-like Endoplasmic Reticulum Kinase (PERK)
- (2012) Jeffrey M. Axten et al. JOURNAL OF MEDICINAL CHEMISTRY
- A Novel, “Double-Clamp” Binding Mode for Human Heme Oxygenase-1 Inhibition
- (2012) Mona N. Rahman et al. PLoS One
- Dihydroartemisinin Exerts Its Anticancer Activity through Depleting Cellular Iron via Transferrin Receptor-1
- (2012) Qian Ba et al. PLoS One
- Spectrum of Cellular Responses to Pyriplatin, a Monofunctional Cationic Antineoplastic Platinum(II) Compound, in Human Cancer Cells
- (2011) K. S. Lovejoy et al. MOLECULAR CANCER THERAPEUTICS
- Primary colon cancer: ESMO Clinical Practice Guidelines for diagnosis, adjuvant treatment and follow-up
- (2010) R. Labianca et al. ANNALS OF ONCOLOGY
- Dihydroartemisinin induces apoptosis in HL-60 leukemia cells dependent of iron and p38 mitogen-activated protein kinase activation but independent of reactive oxygen species
- (2010) Jin-Jian Lu et al. CANCER BIOLOGY & THERAPY
- Iron enhances generation of free radicals by Artemisinin causing a caspase-independent, apoptotic death inLeishmania donovanipromastigotes
- (2010) Rupashree Sen et al. FREE RADICAL RESEARCH
- Reactive oxygen species in cancer
- (2010) Geou-Yarh Liou et al. FREE RADICAL RESEARCH
- The anti-cancer activity of dihydroartemisinin is associated with induction of iron-dependent endoplasmic reticulum stress in colorectal carcinoma HCT116 cells
- (2010) Jin-Jian Lu et al. INVESTIGATIONAL NEW DRUGS
- The Role of Heme and the Mitochondrion in the Chemical and Molecular Mechanisms of Mammalian Cell Death Induced by the Artemisinin Antimalarials
- (2010) Amy E. Mercer et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Artesunate Activates Mitochondrial Apoptosis in Breast Cancer Cells via Iron-catalyzed Lysosomal Reactive Oxygen Species Production
- (2010) Anne Hamacher-Brady et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Targeting the endoplasmic reticulum-stress response as an anticancer strategy
- (2009) Sandra J.M. Healy et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Artemisinin dimer anticancer activity correlates with heme-catalyzed reactive oxygen species generation and endoplasmic reticulum stress induction
- (2009) Luke H. Stockwin et al. INTERNATIONAL JOURNAL OF CANCER
- Targeting cancer cells by ROS-mediated mechanisms: a radical therapeutic approach?
- (2009) Dunyaporn Trachootham et al. NATURE REVIEWS DRUG DISCOVERY
- Heme Mediates Cytotoxicity from Artemisinin and Serves as a General Anti-Proliferation Target
- (2009) Shiming Zhang et al. PLoS One
- Adenoviral endoplasmic reticulum-targeted mda-7/interleukin-24 vector enhances human cancer cell killing
- (2008) A. Pataer et al. MOLECULAR CANCER THERAPEUTICS
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started