Phenotypic and Functional Characterization of NK Cells in αβT-Cell and B-Cell Depleted Haplo-HSCT to Cure Pediatric Patients with Acute Leukemia

Key Aspects of the Immunobiology of Haploidentical Hematopoietic Cell Transplantation

(2020) Susanne H. C. Baumeister et al.   Frontiers in Immunology

Impact of KIR/HLA Incompatibilities on NK Cell Reconstitution and Clinical Outcome after T Cell–Replete Haploidentical Hematopoietic Stem Cell Transplantation with Posttransplant Cyclophosphamide

(2019) Catherine Willem et al.   JOURNAL OF IMMUNOLOGY

Presence of centromeric but absence of telomeric group B KIR haplotypes in stem cell donors improve leukaemia control after HSCT for childhood ALL

(2019) Florian Babor et al.   BONE MARROW TRANSPLANTATION

The Natural Cytotoxicity Receptors in Health and Disease

(2019) Alexander David Barrow et al.   Frontiers in Immunology

Killer Ig-Like Receptors (KIRs): Their Role in NK Cell Modulation and Developments Leading to Their Clinical Exploitation

(2019) Daniela Pende et al.   Frontiers in Immunology

PMN-MDSC are a new target to rescue graft-versus-leukemia activity of NK cells in haplo-HSC transplantation

(2019) Nicola Tumino et al.   LEUKEMIA

The Evolution of T Cell Depleted Haploidentical Transplantation

(2019) Franco Aversa et al.   Frontiers in Immunology

NK Cell Reconstitution in Paediatric Leukemic Patients after T-Cell-Depleted HLA-Haploidentical Haematopoietic Stem Cell Transplantation Followed by the Reinfusion of iCasp9-Modified Donor T Cells

(2019) Helena Stabile et al.   Journal of Clinical Medicine

Killer Cell Immunoglobulin-Like Receptor–Ligand Mismatch in Donor versus Recipient Direction Provides Better Graft-versus-Tumor Effect in Patients with Hematologic Malignancies Undergoing Allogeneic T Cell–Replete Haploidentical Transplantation Followed by Post-Transplant Cyclophosphamide

(2018) Anne Wanquet et al.   BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION

Selecting the Best Donor for Haploidentical Transplant: Impact of HLA, Killer Cell Immunoglobulin-Like Receptor Genotyping, and Other Clinical Variables

(2018) Scott R. Solomon et al.   BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION

Killer cell immunoglobulin-like receptor ligand mismatching and outcome after haploidentical transplantation with post-transplant cyclophosphamide

(2018) Avichai Shimoni et al.   LEUKEMIA

NK Cells Mediate a Crucial Graft-versus-Leukemia Effect in Haploidentical-HSCT to Cure High-Risk Acute Leukemia

(2018) Franco Locatelli et al.   TRENDS IN IMMUNOLOGY

Who is the best donor for haploidentical stem cell transplantation?

(2018) Piyanuch Kongtim et al.   SEMINARS IN HEMATOLOGY

Zoledronic acid boosts γδ T-cell activity in children receiving αβ+ T and CD19+ cell-depleted grafts from an HLA-haplo-identical donor

(2017) A. Bertaina et al.   OncoImmunology

Haploidentical hematopoietic transplantation for the cure of leukemia: from its biology to clinical translation

(2016) A. Mancusi et al.   BLOOD

Naive Donor NK Cell Repertoires Associated with Less Leukemia Relapse after Allogeneic Hematopoietic Stem Cell Transplantation

(2016) Andreas T. Björklund et al.   JOURNAL OF IMMUNOLOGY

Haploidentical transplants using ex vivo T-cell depletion

(2016) Massimo F. Martelli et al.   SEMINARS IN HEMATOLOGY

   T-cell reconstitution after HLA-haploidentical hematopoietic transplantation depleted of TCR-  +/CD19+ lymphocytes

(2015) I. Airoldi et al.   BLOOD

Inducible caspase-9 suicide gene controls adverse effects from alloreplete T cells after haploidentical stem cell transplantation

(2015) X. Zhou et al.   BLOOD

Analysis of memory-like natural killer cells in human cytomegalovirus-infected children undergoing   +T and B cell-depleted hematopoietic stem cell transplantation for hematological malignancies

(2015) L. Muccio et al.   HAEMATOLOGICA

Cytomegalovirus Infection Drives Adaptive Epigenetic Diversification of NK Cells with Altered Signaling and Effector Function

(2015) Heinrich Schlums et al.   IMMUNITY

Epigenetic Modification and Antibody-Dependent Expansion of Memory-like NK Cells in Human Cytomegalovirus-Infected Individuals

(2015) Jaewon Lee et al.   IMMUNITY

CD56dimCD57+NKG2C+ NK cell expansion is associated with reduced leukemia relapse after reduced intensity HCT

(2015) F Cichocki et al.   LEUKEMIA

Analysis of memory-like natural killer cells in human cytomegalovirus-infected children undergoing   +T and B cell-depleted hematopoietic stem cell transplantation for hematological malignancies

(2015) L. Muccio et al.   HAEMATOLOGICA

Both mature KIR+ and immature KIR- NK cells control pediatric acute B-cell precursor leukemia in NOD.Cg-Prkdcscid IL2rgtmWjl/Sz mice

(2014) A. Kubler et al.   BLOOD

KIR B haplotype donors confer a reduced risk for relapse after haploidentical transplantation in children with ALL

(2014) L. Oevermann et al.   BLOOD

HLA-haploidentical stem cell transplantation after removal of   + T and B cells in children with nonmalignant disorders

(2014) A. Bertaina et al.   BLOOD

Recognition of adult and pediatric acute lymphoblastic leukemia blasts by natural killer cells

(2014) G. F. Torelli et al.   HAEMATOLOGICA

Synergistic Polymorphism at Two Positions Distal to the Ligand-Binding Site Makes KIR2DL2 a Stronger Receptor for HLA-C Than KIR2DL3

(2014) A. K. Moesta et al.   JOURNAL OF IMMUNOLOGY

Human Cytomegalovirus Infection Promotes Rapid Maturation of NK Cells Expressing Activating Killer Ig-like Receptor in Patients Transplanted with NKG2C-/- Umbilical Cord Blood

(2014) M. Della Chiesa et al.   JOURNAL OF IMMUNOLOGY

At the Bench: Preclinical rationale for exploiting NK cells and γδ T lymphocytes for the treatment of high-risk leukemias

(2013) Håkan Norell et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Cellular and molecular basis of haploidentical hematopoietic stem cell transplantation in the successful treatment of high-risk leukemias: role of alloreactive NK cells

(2013) Franco Locatelli et al.   Frontiers in Immunology

Human Cytomegalovirus (CMV)-Induced Memory-like NKG2C+ NK Cells Are Transplantable and Expand In Vivo in Response to Recipient CMV Antigen

(2012) B. Foley et al.   JOURNAL OF IMMUNOLOGY

HLA-C–Dependent Prevention of Leukemia Relapse by Donor ActivatingKIR2DS1

(2012) Jeffrey M. Venstrom et al.   NEW ENGLAND JOURNAL OF MEDICINE

New Approaches to Graft Engineering for Haploidentical Bone Marrow Transplantation

(2012) Rupert Handgretinger   SEMINARS IN ONCOLOGY

Phenotypic and functional heterogeneity of human NK cells developing after umbilical cord blood transplantation: a role for human cytomegalovirus?

(2011) M. Della Chiesa et al.   BLOOD

Cytomegalovirus reactivation after allogeneic transplantation promotes a lasting increase in educated NKG2C+ natural killer cells with potent function

(2011) B. Foley et al.   BLOOD

Donor selection for natural killer cell receptor genes leads to superior survival after unrelated transplantation for acute myelogenous leukemia

(2010) S. Cooley et al.   BLOOD

Combined Genotypic and Phenotypic Killer Cell Ig-Like Receptor Analyses Reveal KIR2DL3 Alleles Displaying Unexpected Monoclonal Antibody Reactivity: Identification of the Amino Acid Residues Critical for Staining

(2010) M. Falco et al.   JOURNAL OF IMMUNOLOGY

Improved Survival with Inhibitory Killer Immunoglobulin Receptor (KIR) Gene Mismatches and KIR Haplotype B Donors after Nonmyeloablative, HLA-Haploidentical Bone Marrow Transplantation

(2009) Heather J. Symons et al.   BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION

Education of human natural killer cells by activating killer cell immunoglobulin-like receptors

(2009) C. Fauriat et al.   BLOOD

The B7 family member B7-H6 is a tumor cell ligand for the activating natural killer cell receptor NKp30 in humans

(2009) Cameron S. Brandt et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Human leukocyte antigens A23, A24, and A32 but not A25 are ligands for KIR3DL1

(2008) M. Stern et al.   BLOOD

Anti-leukemia activity of alloreactive NK cells in KIR ligand-mismatched haploidentical HSCT for pediatric patients: evaluation of the functional role of activating KIR and redefinition of inhibitory KIR specificity

(2008) D. Pende et al.   BLOOD