The clonal repopulation of HSPC gene modified with anti–HIV-1 RNAi is not affected by preexisting HIV-1 infection
出版年份 2020 全文链接
标题
The clonal repopulation of HSPC gene modified with anti–HIV-1 RNAi is not affected by preexisting HIV-1 infection
作者
关键词
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出版物
Science Advances
Volume 6, Issue 30, Pages eaay9206
出版商
American Association for the Advancement of Science (AAAS)
发表日期
2020-07-23
DOI
10.1126/sciadv.aay9206
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- HIV-1 remission following CCR5Δ32/Δ32 haematopoietic stem-cell transplantation
- (2019) Ravindra K. Gupta et al. NATURE
- The impact of aging on primate hematopoiesis as interrogated by clonal tracking
- (2018) Kyung-Rok Yu et al. BLOOD
- Causes and Consequences of Hematopoietic Stem Cell Heterogeneity
- (2018) Simon Haas et al. Cell Stem Cell
- Niches for Hematopoietic Stem Cells and Their Progeny
- (2018) Qiaozhi Wei et al. IMMUNITY
- Modeling the human bone marrow niche in mice: From host bone marrow engraftment to bioengineering approaches
- (2018) Ander Abarrategi et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Modeling Anti-HIV-1 HSPC-Based Gene Therapy in Humanized Mice Previously Infected with HIV-1
- (2018) Wannisa Khamaikawin et al. Molecular Therapy-Methods & Clinical Development
- Dynamics of genetically engineered hematopoietic stem and progenitor cells after autologous transplantation in humans
- (2018) Serena Scala et al. NATURE MEDICINE
- Geographic clonal tracking in macaques provides insights into HSPC migration and differentiation
- (2017) Chuanfeng Wu et al. JOURNAL OF EXPERIMENTAL MEDICINE
- A distinct hematopoietic stem cell population for rapid multilineage engraftment in nonhuman primates
- (2017) Stefan Radtke et al. Science Translational Medicine
- Dynamics and mechanisms of clonal expansion of HIV-1-infected cells in a humanized mouse model
- (2017) Yorifumi Satou et al. Scientific Reports
- Long-term persistence and function of hematopoietic stem cell-derived chimeric antigen receptor T cells in a nonhuman primate model of HIV/AIDS
- (2017) Anjie Zhen et al. PLoS Pathogens
- Efficient Ex Vivo Engineering and Expansion of Highly Purified Human Hematopoietic Stem and Progenitor Cell Populations for Gene Therapy
- (2017) Erika Zonari et al. Stem Cell Reports
- Humanized Mouse Models for Human Immunodeficiency Virus Infection
- (2017) Matthew D. Marsden et al. Annual Review of Virology
- What Integration Sites Tell Us about HIV Persistence
- (2016) Stephen H. Hughes et al. Cell Host & Microbe
- In Vivo Tracking of Human Hematopoiesis Reveals Patterns of Clonal Dynamics during Early and Steady-State Reconstitution Phases
- (2016) Luca Biasco et al. Cell Stem Cell
- Clonally expanded CD4+T cells can produce infectious HIV-1 in vivo
- (2016) Francesco R. Simonetti et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Propagating Humanized BLT Mice for the Study of Human Immunology and Immunotherapy
- (2016) Drake J. Smith et al. STEM CELLS AND DEVELOPMENT
- Multilineage polyclonal engraftment of Cal-1 gene-modified cells and in vivo selection after SHIV infection in a nonhuman primate model of AIDS
- (2016) Christopher W. Peterson et al. Molecular Therapy-Methods & Clinical Development
- Lack of viral control and development of combination antiretroviral therapy escape mutations in macaques after bone marrow transplantation
- (2015) Christopher W. Peterson et al. AIDS
- Mechanisms of blood homeostasis: lineage tracking and a neutral model of cell populations in rhesus macaques
- (2015) Sidhartha Goyal et al. BMC BIOLOGY
- Lentivirus-mediated Gene Transfer in Hematopoietic Stem Cells Is Impaired in SHIV-infected, ART-treated Nonhuman Primates
- (2015) Patrick M Younan et al. MOLECULAR THERAPY
- Development of a diverse human T-cell repertoire despite stringent restriction of hematopoietic clonality in the thymus
- (2015) Martijn H. Brugman et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- RNAi-Mediated CCR5 Knockdown Provides HIV-1 Resistance to Memory T Cells in Humanized BLT Mice
- (2015) Saki Shimizu et al. Molecular Therapy-Nucleic Acids
- Engineering Cellular Resistance to HIV-1 Infection In Vivo Using a Dual Therapeutic Lentiviral Vector
- (2015) Bryan P Burke et al. Molecular Therapy-Nucleic Acids
- Dynamics of HSPC Repopulation in Nonhuman Primates Revealed by a Decade-Long Clonal-Tracking Study
- (2014) Sanggu Kim et al. Cell Stem Cell
- Cellular barcoding: A technical appraisal
- (2014) Shalin H. Naik et al. EXPERIMENTAL HEMATOLOGY
- Engineering HIV-1-Resistant T-Cells from Short-Hairpin RNA-Expressing Hematopoietic Stem/Progenitor Cells in Humanized BLT Mice
- (2013) Gene-Errol E. Ringpis et al. PLoS One
- SSW Library: An SIMD Smith-Waterman C/C++ Library for Use in Genomic Applications
- (2013) Mengyao Zhao et al. PLoS One
- Lentiviral Hematopoietic Stem Cell Gene Therapy in Patients with Wiskott-Aldrich Syndrome
- (2013) A. Aiuti et al. SCIENCE
- Lentiviral Hematopoietic Stem Cell Gene Therapy Benefits Metachromatic Leukodystrophy
- (2013) A. Biffi et al. SCIENCE
- Counting stem cells: methodological constraints
- (2012) Leonid V Bystrykh et al. NATURE METHODS
- Isolation of Single Human Hematopoietic Stem Cells Capable of Long-Term Multilineage Engraftment
- (2011) F. Notta et al. SCIENCE
- HIV Status Does Not Affect the Outcome of Autologous Stem Cell Transplantation (ASCT) for Non-Hodgkin Lymphoma (NHL)
- (2010) Amrita Krishnan et al. BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION
- Evidence for the cure of HIV infection by CCR5 32/ 32 stem cell transplantation
- (2010) K. Allers et al. BLOOD
- Human hematopoietic stem/progenitor cells modified by zinc-finger nucleases targeted to CCR5 control HIV-1 in vivo
- (2010) Nathalia Holt et al. NATURE BIOTECHNOLOGY
- HIV-1 infects multipotent progenitor cells causing cell death and establishing latent cellular reservoirs
- (2010) Christoph C Carter et al. NATURE MEDICINE
- RNA-Based Gene Therapy for HIV with Lentiviral Vector-Modified CD34+ Cells in Patients Undergoing Transplantation for AIDS-Related Lymphoma
- (2010) D. L. DiGiusto et al. Science Translational Medicine
- Fast and accurate short read alignment with Burrows-Wheeler transform
- (2009) H. Li et al. BIOINFORMATICS
- Comparable survival between HIV+ and HIV- non-Hodgkin and Hodgkin lymphoma patients undergoing autologous peripheral blood stem cell transplantation
- (2009) J. L. Diez-Martin et al. BLOOD
- A highly efficient short hairpin RNA potently down-regulates CCR5 expression in systemic lymphoid organs in the hu-BLT mouse model
- (2009) S. Shimizu et al. BLOOD
- Phase 2 gene therapy trial of an anti-HIV ribozyme in autologous CD34+ cells
- (2009) Ronald T Mitsuyasu et al. NATURE MEDICINE
- Long-Term Control of HIV byCCR5Delta32/Delta32 Stem-Cell Transplantation
- (2009) Gero Hütter et al. NEW ENGLAND JOURNAL OF MEDICINE
- Hematopoietic Stem Cell Gene Therapy with a Lentiviral Vector in X-Linked Adrenoleukodystrophy
- (2009) N. Cartier et al. SCIENCE
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