标题
New insights into the mechanism of dynein motor regulation by lissencephaly-1
作者
关键词
-
出版物
eLife
Volume 9, Issue -, Pages -
出版商
eLife Sciences Publications, Ltd
发表日期
2020-07-22
DOI
10.7554/elife.59737
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- LIS1 promotes the formation of activated cytoplasmic dynein-1 complexes
- (2020) Zaw Min Htet et al. NATURE CELL BIOLOGY
- Lis1 activates dynein motility by modulating its pairing with dynactin
- (2020) Mohamed M. Elshenawy et al. NATURE CELL BIOLOGY
- Pac1/LIS1 stabilizes an uninhibited conformation of dynein to coordinate its localization and activity
- (2020) Matthew G. Marzo et al. NATURE CELL BIOLOGY
- Lis1 co‐localizes with actin in the phagocytic cup and regulates phagocytosis
- (2020) Aditya Chhatre et al. Cytoskeleton
- LIS1 regulates cargo-adapter–mediated activation of dynein by overcoming its autoinhibition in vivo
- (2019) Rongde Qiu et al. JOURNAL OF CELL BIOLOGY
- Microtubules gate tau condensation to spatially regulate microtubule functions
- (2019) Ruensern Tan et al. NATURE CELL BIOLOGY
- Structure of the dynein-2 complex and its assembly with intraflagellar transport trains
- (2019) Katerina Toropova et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Analysis of 17 genes detects mutations in 81% of 811 patients with lissencephaly
- (2018) Nataliya Di Donato et al. GENETICS IN MEDICINE
- The cytoplasmic dynein transport machinery and its many cargoes
- (2018) Samara L. Reck-Peterson et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Cryo-electron tomography reveals that dynactin recruits a team of dyneins for processive motility
- (2018) Danielle A. Grotjahn et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Cryo-electron tomography reveals that dynactin recruits a team of dyneins for processive motility
- (2018) Danielle A. Grotjahn et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Dynein–Dynactin–NuMA clusters generate cortical spindle-pulling forces as a multi-arm ensemble
- (2018) Masako Okumura et al. eLife
- Cryo-EM shows how dynactin recruits two dyneins for faster movement
- (2018) Linas Urnavicius et al. NATURE
- The cryo-EM structure of intraflagellar transport trains reveals how dynein is inactivated to ensure unidirectional anterograde movement in cilia
- (2018) Mareike A. Jordan et al. NATURE CELL BIOLOGY
- Differential effects of the dynein-regulatory factor Lissencephaly-1 on processive dynein-dynactin motility
- (2017) Pedro A. Gutierrez et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Two populations of cytoplasmic dynein contribute to spindle positioning in C. elegans embryos
- (2017) Ruben Schmidt et al. JOURNAL OF CELL BIOLOGY
- Neuropathological Hallmarks of Brain Malformations in Extreme Phenotypes Related to DYNC1H1 Mutations
- (2017) Annie Laquerriere et al. JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY
- WD40 repeat domain proteins: a novel target class?
- (2017) Matthieu Schapira et al. NATURE REVIEWS DRUG DISCOVERY
- Intraflagellar transport dynein is autoinhibited by trapping of its mechanical and track-binding elements
- (2017) Katerina Toropova et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Intraflagellar transport dynein is autoinhibited by trapping of its mechanical and track-binding elements
- (2017) Katerina Toropova et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Lissencephaly-1 is a context-dependent regulator of the human dynein complex
- (2017) Janina Baumbach et al. eLife
- Review: Structure and mechanism of the dynein motor ATPase
- (2016) Helgo Schmidt et al. BIOPOLYMERS
- Tyrosination of α‐tubulin controls the initiation of processive dynein–dynactin motility
- (2016) Richard J McKenney et al. EMBO JOURNAL
- Nuclear migration events throughout development
- (2016) Courtney R. Bone et al. JOURNAL OF CELL SCIENCE
- The mammalian dynein–dynactin complex is a strong opponent to kinesin in a tug-of-war competition
- (2016) Vladislav Belyy et al. NATURE CELL BIOLOGY
- Load-induced enhancement of Dynein force production by LIS1–NudE in vivo and in vitro
- (2016) Babu J. N. Reddy et al. Nature Communications
- Severe NDE1-mediated microcephaly results from neural progenitor cell cycle arrests at multiple specific stages
- (2016) David J. Doobin et al. Nature Communications
- α-Tubulin Tyrosination and CLIP-170 Phosphorylation Regulate the Initiation of Dynein-Driven Transport in Neurons
- (2016) Jeffrey J. Nirschl et al. Cell Reports
- Dynein motors: How AAA+ ring opening and closing coordinates microtubule binding and linker movement
- (2015) Helgo Schmidt BIOESSAYS
- Cdk1 Activates Pre-mitotic Nuclear Envelope Dynein Recruitment and Apical Nuclear Migration in Neural Stem Cells
- (2015) Alexandre D. Baffet et al. DEVELOPMENTAL CELL
- The dynein cortical anchor Num1 activates dynein motility by relieving Pac1/LIS1-mediated inhibition
- (2015) Lindsay G. Lammers et al. JOURNAL OF CELL BIOLOGY
- Cytoplasmic dynein regulates its attachment to microtubules via nucleotide state-switched mechanosensing at multiple AAA domains
- (2015) Matthew P. Nicholas et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The structure of the dynactin complex and its interaction with dynein
- (2015) L. Urnavicius et al. SCIENCE
- Joined at the hip: kinetochores, microtubules, and spindle assembly checkpoint signaling
- (2015) Carlos Sacristan et al. TRENDS IN CELL BIOLOGY
- Allosteric Communication in the Dynein Motor Domain
- (2014) Gira Bhabha et al. CELL
- Astral microtubules control redistribution of dynein at the cell cortex to facilitate spindle positioning
- (2014) Mihoko Tame et al. CELL CYCLE
- In vitroreconstitution of a highly processive recombinant human dynein complex
- (2014) Max A Schlager et al. EMBO JOURNAL
- SUN proteins facilitate the removal of membranes from chromatin during nuclear envelope breakdown
- (2014) Yagmur Turgay et al. JOURNAL OF CELL BIOLOGY
- Reconstitution of a hierarchical +TIP interaction network controlling microtubule end tracking of dynein
- (2014) Christian Duellberg et al. NATURE CELL BIOLOGY
- The AAA3 domain of cytoplasmic dynein acts as a switch to facilitate microtubule release
- (2014) Mark A DeWitt et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Activation of cytoplasmic dynein motility by dynactin-cargo adapter complexes
- (2014) R. J. McKenney et al. SCIENCE
- Reconstitution of dynein transport to the microtubule plus end by kinesin
- (2014) Anthony J Roberts et al. eLife
- Lis1 regulates dynein by sterically blocking its mechanochemical cycle
- (2014) Katerina Toropova et al. eLife
- The scaffold protein Nde1 safeguards the brain genome during S phase of early neural progenitor differentiation
- (2014) Shauna L Houlihan et al. eLife
- Dynein Recruitment to Nuclear Pores Activates Apical Nuclear Migration and Mitotic Entry in Brain Progenitor Cells
- (2013) Daniel Jun-Kit Hu et al. CELL
- Cortical Dynein and Asymmetric Membrane Elongation Coordinately Position the Spindle in Anaphase
- (2013) Tomomi Kiyomitsu et al. CELL
- LIS1 controls mitosis and mitotic spindle organization via the LIS1–NDEL1–dynein complex
- (2013) Hyang Mi Moon et al. HUMAN MOLECULAR GENETICS
- Lissencephaly-1 promotes the recruitment of dynein and dynactin to transported mRNAs
- (2013) Carly I. Dix et al. JOURNAL OF CELL BIOLOGY
- Systematic dissection of dynein regulators in mitosis
- (2013) Jonne A. Raaijmakers et al. JOURNAL OF CELL BIOLOGY
- Ordered Recruitment of Dynactin to the Microtubule Plus-End is Required for Efficient Initiation of Retrograde Axonal Transport
- (2013) A. J. Moughamian et al. JOURNAL OF NEUROSCIENCE
- Nudel/NudE and Lis1 promote dynein and dynactin interaction in the context of spindle morphogenesis
- (2013) Shusheng Wang et al. MOLECULAR BIOLOGY OF THE CELL
- Mutations in TUBG1, DYNC1H1, KIF5C and KIF2A cause malformations of cortical development and microcephaly
- (2013) Karine Poirier et al. NATURE GENETICS
- The Phosphatase PP4c Controls Spindle Orientation to Maintain Proliferative Symmetric Divisions in the Developing Neocortex
- (2013) Yunli Xie et al. NEURON
- Dynein and Dynactin Leverage Their Bivalent Character to Form a High-Affinity Interaction
- (2013) Amanda E. Siglin et al. PLoS One
- Lis1 Acts as a “Clutch” between the ATPase and Microtubule-Binding Domains of the Dynein Motor
- (2012) Julie Huang et al. CELL
- Connecting the nucleus to the cytoskeleton by SUN–KASH bridges across the nuclear envelope
- (2012) Erin C Tapley et al. CURRENT OPINION IN CELL BIOLOGY
- Astral microtubule asymmetry provides directional cues for spindle positioning in budding yeast
- (2012) Steven M. Markus et al. EXPERIMENTAL CELL RESEARCH
- Intrinsic Disorder in Dynein Intermediate Chain Modulates Its Interactions with NudE and Dynactin
- (2012) Afua Nyarko et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- A novel patch assembly domain in Num1 mediates dynein anchoring at the cortex during spindle positioning
- (2012) Xianying Tang et al. JOURNAL OF CELL BIOLOGY
- Lis1 is an initiation factor for dynein-driven organelle transport
- (2012) Martin J. Egan et al. JOURNAL OF CELL BIOLOGY
- Mutations inDYNC1H1cause severe intellectual disability with neuronal migration defects
- (2012) Marjolein H Willemsen et al. JOURNAL OF MEDICAL GENETICS
- BICD2, dynactin, and LIS1 cooperate in regulating dynein recruitment to cellular structures
- (2012) Daniël Splinter et al. MOLECULAR BIOLOGY OF THE CELL
- Chromosome- and spindle-pole-derived signals generate an intrinsic code for spindle position and orientation
- (2012) Tomomi Kiyomitsu et al. NATURE CELL BIOLOGY
- Microtubule attachment and spindle assembly checkpoint signalling at the kinetochore
- (2012) Emily A. Foley et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Human Mutations in NDE1 Cause Extreme Microcephaly with Lissencephaly
- (2011) Fowzan S. Alkuraya et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Quantitative analysis of Pac1/LIS1-mediated dynein targeting: Implications for regulation of dynein activity in budding yeast
- (2011) Steven M. Markus et al. Cytoskeleton
- Regulated Offloading of Cytoplasmic Dynein from Microtubule Plus Ends to the Cortex
- (2011) Steven M. Markus et al. DEVELOPMENTAL CELL
- Mitotic Spindle Orientation in Asymmetric and Symmetric Cell Divisions during Animal Development
- (2011) Xavier Morin et al. DEVELOPMENTAL CELL
- Controlled and stochastic retention concentrates dynein at microtubule ends to keep endosomes on track
- (2011) Martin Schuster et al. EMBO JOURNAL
- Mutually Exclusive Cytoplasmic Dynein Regulation by NudE-Lis1 and Dynactin
- (2011) Richard J. McKenney et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- A lateral belt of cortical LGN and NuMA guides mitotic spindle movements and planar division in neuroepithelial cells
- (2011) Elise Peyre et al. JOURNAL OF CELL BIOLOGY
- The N-terminal coiled-coil of Ndel1 is a regulated scaffold that recruits LIS1 to dynein
- (2011) Eliza Żyłkiewicz et al. JOURNAL OF CELL BIOLOGY
- A Nup133-dependent NPC-anchored network tethers centrosomes to the nuclear envelope in prophase
- (2011) Stéphanie Bolhy et al. JOURNAL OF CELL BIOLOGY
- High-resolution imaging reveals indirect coordination of opposite motors and a role for LIS1 in high-load axonal transport
- (2011) Julie Y. Yi et al. JOURNAL OF CELL BIOLOGY
- A Cdk5-Dependent Switch Regulates Lis1/Ndel1/Dynein-Driven Organelle Transport in Adult Axons
- (2011) J. P. Pandey et al. JOURNAL OF NEUROSCIENCE
- Functional interaction between dynein light chain and intermediate chain is required for mitotic spindle positioning
- (2011) Melissa D. Stuchell-Brereton et al. MOLECULAR BIOLOGY OF THE CELL
- In Vivo Roles of the Basic Domain of Dynactin p150 in Microtubule Plus-End Tracking and Dynein Function
- (2011) Xuanli Yao et al. TRAFFIC
- LIS1 and NudE Induce a Persistent Dynein Force-Producing State
- (2010) Richard J. McKenney et al. CELL
- Functional Dissection of LIS1 and NDEL1 Towards Understanding the Molecular Mechanisms of Cytoplasmic Dynein Regulation
- (2010) Takayuki Torisawa et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Identification of a Novel Dynein Binding Domain in Nudel Essential for Spindle Pole Organization inXenopusEgg Extract
- (2010) Shusheng Wang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The microtubule plus-end localization of Aspergillus dynein is important for dynein-early-endosome interaction but not for dynein ATPase activation
- (2010) J. Zhang et al. JOURNAL OF CELL SCIENCE
- Ric-8A and Gi Recruit LGN, NuMA, and Dynein to the Cell Cortex To Help Orient the Mitotic Spindle
- (2010) G. E. Woodard et al. MOLECULAR AND CELLULAR BIOLOGY
- A de novo paradigm for mental retardation
- (2010) Lisenka E L M Vissers et al. NATURE GENETICS
- Kinesin 3 and cytoplasmic dynein mediate interkinetic nuclear migration in neural stem cells
- (2010) Jin-Wu Tsai et al. NATURE NEUROSCIENCE
- Asymmetric cell division: recent developments and their implications for tumour biology
- (2010) Juergen A. Knoblich NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Bicaudal D2, Dynein, and Kinesin-1 Associate with Nuclear Pore Complexes and Regulate Centrosome and Nuclear Positioning during Mitotic Entry
- (2010) Daniël Splinter et al. PLOS BIOLOGY
- Motor- and Tail-Dependent Targeting of Dynein to Microtubule Plus Ends and the Cell Cortex
- (2009) Steven M. Markus et al. CURRENT BIOLOGY
- Opposing effects of Ndel1 and 1 or 2 on cytoplasmic dynein through competitive binding to Lis1
- (2009) C. Ding et al. JOURNAL OF CELL SCIENCE
- Spindle orientation during asymmetric cell division
- (2009) Karsten H. Siller et al. NATURE CELL BIOLOGY
- Neuronal migration disorders
- (2009) Renzo Guerrini et al. NEUROBIOLOGY OF DISEASE
- Emerging roles for myosin II and cytoplasmic dynein in migrating neurons and growth cones
- (2009) Richard B. Vallee et al. TRENDS IN CELL BIOLOGY
- Function of dynein in budding yeast: Mitotic spindle positioning in a polarized cell
- (2009) Jeffrey K. Moore et al. CELL MOTILITY AND THE CYTOSKELETON
- Neuroepithelial Stem Cell Proliferation Requires LIS1 for Precise Spindle Orientation and Symmetric Division
- (2008) Jessica Yingling et al. CELL
- LIS1 and NDEL1 coordinate the plus-end-directed transport of cytoplasmic dynein
- (2008) Masami Yamada et al. EMBO JOURNAL
- Lis1–Nde1-dependent neuronal fate control determines cerebral cortical size and lamination
- (2008) Ashley S. Pawlisz et al. HUMAN MOLECULAR GENETICS
- Lis1 and Ndel1 influence the timing of nuclear envelope breakdown in neural stem cells
- (2008) Sachin Hebbar et al. JOURNAL OF CELL BIOLOGY
- Dynactin Function in Mitotic Spindle Positioning
- (2008) Jeffrey K. Moore et al. TRAFFIC
- Arp11 Affects Dynein–Dynactin Interaction and is Essential for Dynein Function in Aspergillus nidulans
- (2008) Jun Zhang et al. TRAFFIC
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