The structure of the dynactin complex and its interaction with dynein

How cryo-EM is revolutionizing structural biology

(2015) Xiao-chen Bai et al.   TRENDS IN BIOCHEMICAL SCIENCES

In vitroreconstitution of a highly processive recombinant human dynein complex

(2014) Max A Schlager et al.   EMBO JOURNAL

Dynactin 3D Structure: Implications for Assembly and Dynein Binding

(2014) Hiroshi Imai et al.   JOURNAL OF MOLECULAR BIOLOGY

Dynactin integrity depends upon direct binding of dynamitin to Arp1

(2014) Frances Ka Yan Cheong et al.   MOLECULAR BIOLOGY OF THE CELL

Autoinhibition and cooperative activation mechanisms of cytoplasmic dynein

(2014) Takayuki Torisawa et al.   NATURE CELL BIOLOGY

Reconstitution of a hierarchical +TIP interaction network controlling microtubule end tracking of dynein

(2014) Christian Duellberg et al.   NATURE CELL BIOLOGY

Autoregulatory mechanism for dynactin control of processive and diffusive dynein transport

(2014) Suvranta K. Tripathy et al.   NATURE CELL BIOLOGY

Activation of cytoplasmic dynein motility by dynactin-cargo adapter complexes

(2014) R. J. McKenney et al.   SCIENCE

Beam-induced motion correction for sub-megadalton cryo-EM particles

(2014) Sjors HW Scheres   eLife

Dynactin helps target Polo-like kinase 1 to kinetochores via its left-handed beta-helical p27 subunit

(2013) Ting-Yu Yeh et al.   EMBO JOURNAL

Bicaudal-D uses a parallel, homodimeric coiled coil with heterotypic registry to coordinate recruitment of cargos to dynein

(2013) Y. Liu et al.   GENES & DEVELOPMENT

Electron counting and beam-induced motion correction enable near-atomic-resolution single-particle cryo-EM

(2013) Xueming Li et al.   NATURE METHODS

TRAK/Milton Motor-Adaptor Proteins Steer Mitochondrial Trafficking to Axons and Dendrites

(2013) Myrrhe van Spronsen et al.   NEURON

Dynein and Dynactin Leverage Their Bivalent Character to Form a High-Affinity Interaction

(2013) Amanda E. Siglin et al.   PLoS One

Cytoplasmic dynein heavy chain: the servant of many masters

(2013) Giampietro Schiavo et al.   TRENDS IN NEUROSCIENCES

Cytoplasmic dynein

(2012) Victoria J. Allan   BIOCHEMICAL SOCIETY TRANSACTIONS

Evolution of the eukaryotic dynactin complex, the activator of cytoplasmic dynein

(2012) Björn Hammesfahr et al.   BMC EVOLUTIONARY BIOLOGY

Structure of the Rigor Actin-Tropomyosin-Myosin Complex

(2012) Elmar Behrmann et al.   CELL

RELION: Implementation of a Bayesian approach to cryo-EM structure determination

(2012) Sjors H.W. Scheres   JOURNAL OF STRUCTURAL BIOLOGY

Dynactin's pointed-end complex is a cargo-targeting module

(2012) Ting-Yu Yeh et al.   MOLECULAR BIOLOGY OF THE CELL

BICD2, dynactin, and LIS1 cooperate in regulating dynein recruitment to cellular structures

(2012) Daniël Splinter et al.   MOLECULAR BIOLOGY OF THE CELL

iMOSFLM: a new graphical interface for diffraction-image processing withMOSFLM

(2011) T. Geoff G. Battye et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

REFMAC5 for the refinement of macromolecular crystal structures

(2011) Garib N. Murshudov et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Overview of theCCP4 suite and current developments

(2011) Martyn D. Winn et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Coupling viruses to dynein and kinesin-1

(2011) Mark P Dodding et al.   EMBO JOURNAL

Global quantification of mammalian gene expression control

(2011) Björn Schwanhäusser et al.   NATURE

Bicaudal-D and its role in cargo sorting by microtubule-based motors

(2009) Martin Dienstbier et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Protein structure prediction on the Web: a case study using the Phyre server

(2009) Lawrence A Kelley et al.   Nature Protocols

MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification

(2008) Jürgen Cox et al.   NATURE BIOTECHNOLOGY

Image processing for electron microscopy single-particle analysis using XMIPP

(2008) Sjors H W Scheres et al.   Nature Protocols