In-silico prediction of drug targets, biological activities, signal pathways and regulating networks of dioscin based on bioinformatics

Reverse docking: a powerful tool for drug repositioning and drug rescue

(2014) Prashant S Kharkar et al.   Future Medicinal Chemistry

Antioxidant sulforaphane and sensitizer trinitrobenzene sulfonate induce carboxylesterase-1 through a novel element transactivated by nuclear factor-E2 related factor-2

(2012) Yi-Tzai Chen et al.   BIOCHEMICAL PHARMACOLOGY

Searching for transcription factor binding sites in vector spaces

(2012) Chih Lee et al.   BMC BIOINFORMATICS

Dioscin induces cancer cell apoptosis through elevated oxidative stress mediated by downregulation of peroxiredoxins

(2012) Wang Zhiyu et al.   CANCER BIOLOGY & THERAPY

Mechanism investigation of dioscin against CCl 4 -induced acute liver damage in mice

(2012) Binan Lu et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

ESR1 gene status correlates with estrogen receptor protein levels measured by ligand binding assay and immunohistochemistry

(2012) Anne-Vibeke Laenkholm et al.   Molecular Oncology

Curcumin attenuates rat thoracic aortic aneurysm formation by inhibition of the c-Jun N-terminal kinase pathway and apoptosis

(2012) Jun Fan et al.   NUTRITION

Staphylococcus aureus Proteins Sbi and Efb Recruit Human Plasmin to Degrade Complement C3 and C3b

(2012) Tina K. Koch et al.   PLoS One

Inhibition of EGF/EGFR activation with naphtho[1,2-b]furan-4,5-dione blocks migration and invasion of MDA-MB-231 cells

(2012) Chi-Ying Hsieh et al.   TOXICOLOGY IN VITRO

Dioscin, a natural steroid saponin, shows remarkable protective effect against acetaminophen-induced liver damage in vitro and in vivo

(2012) Xiaoming Zhao et al.   TOXICOLOGY LETTERS

Enabling enrichment analysis with the Human Disease Ontology

(2011) Paea LePendu et al.   JOURNAL OF BIOMEDICAL INFORMATICS

An inverse docking approach for identifying new potential anti-cancer targets

(2011) Sam Z. Grinter et al.   JOURNAL OF MOLECULAR GRAPHICS & MODELLING

C-jun phosphorylation contributes to down regulation of neuronal nitric oxide synthase protein and motoneurons death in injured spinal cords following root-avulsion of the brachial plexus

(2011) L.-L. Wang et al.   NEUROSCIENCE

Paris chinensisdioscin induces G2/M cell cycle arrest and apoptosis in human gastric cancer SGC-7901 cells

(2011) Lin-Lin Gao   WORLD JOURNAL OF GASTROENTEROLOGY

Post-docking virtual screening of diverse binding pockets: Comparative study using DOCK, AMMOS, X-Score and FRED scoring functions

(2010) Tania Pencheva et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Evaluation of various inverse docking schemes in multiple targets identification

(2010) Liu Hui-fang et al.   JOURNAL OF MOLECULAR GRAPHICS & MODELLING

Application of Proteomic and Bioinformatic Techniques for Studying the Hepatoprotective Effect of Dioscin against CCl4-induced Liver Damage in Mice

(2010) Binan Lu et al.   PLANTA MEDICA

Supervised prediction of drug–target interactions using bipartite local models

(2009) Kevin Bleakley et al.   BIOINFORMATICS

The expression of inducible nitric oxide synthase in the human fallopian tube during the menstrual cycle and in ectopic pregnancy

(2009) Majedah Al-Azemi et al.   FERTILITY AND STERILITY

Predicting new molecular targets for known drugs

(2009) Michael J. Keiser et al.   NATURE

PDTD: a web-accessible protein database for drug target identification

(2008) Zhenting Gao et al.   BMC BIOINFORMATICS

Expression, essentiality, and a microtiter plate assay for mycobacterial GlmU, the bifunctional glucosamine-1-phosphate acetyltransferase and N-acetylglucosamine-1-phosphate uridyltransferase

(2008) Wenli Zhang et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Drug Target Identification Using Side-Effect Similarity

(2008) M. Campillos et al.   SCIENCE