Integrated pharmaco-proteogenomics defines two subgroups in isocitrate dehydrogenase wild-type glioblastoma with prognostic and therapeutic opportunities
出版年份 2020 全文链接
标题
Integrated pharmaco-proteogenomics defines two subgroups in isocitrate dehydrogenase wild-type glioblastoma with prognostic and therapeutic opportunities
作者
关键词
-
出版物
Nature Communications
Volume 11, Issue 1, Pages -
出版商
Springer Science and Business Media LLC
发表日期
2020-07-03
DOI
10.1038/s41467-020-17139-y
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- The landscape of cancer cell line metabolism
- (2019) Haoxin Li et al. NATURE MEDICINE
- Neutralizing the Detrimental Effect of an N-Hydroxysuccinimide Quenching Reagent on Phosphopeptide in Quantitative Proteomics
- (2018) Yumi Kwon et al. ANALYTICAL CHEMISTRY
- Comprehensive and sensitive proteogenomics data analysis strategy based on complementary multi-stage database search
- (2018) Inamul Hasan Madar et al. INTERNATIONAL JOURNAL OF MASS SPECTROMETRY
- WHO 2016 Classification of gliomas
- (2018) P. Wesseling et al. NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY
- An anatomic transcriptional atlas of human glioblastoma
- (2018) Ralph B. Puchalski et al. SCIENCE
- PP242 Counteracts Glioblastoma Cell Proliferation, Migration, Invasiveness and Stemness Properties by Inhibiting mTORC2/AKT
- (2018) Carmen Mecca et al. Frontiers in Cellular Neuroscience
- Human glioblastoma arises from subventricular zone cells with low-level driver mutations
- (2018) Joo Ho Lee et al. NATURE
- Pharmacogenomic landscape of patient-derived tumor cells informs precision oncology therapy
- (2018) Jin-Ku Lee et al. NATURE GENETICS
- Overcoming therapeutic resistance in glioblastoma: the way forward
- (2017) Satoru Osuka et al. JOURNAL OF CLINICAL INVESTIGATION
- IDH1 Mutation and World Health Organization 2016 Diagnostic Criteria for Adult Diffuse Gliomas: Advances in Surgical Strategy
- (2017) Kensuke Tateishi et al. NEUROSURGERY
- Multi-pronged proteomic analysis to study the glioma pathobiology using cerebrospinal fluid samples
- (2017) Nikita Gahoi et al. Proteomics Clinical Applications
- A pathology atlas of the human cancer transcriptome
- (2017) Mathias Uhlen et al. SCIENCE
- Proteogenomic characterization and integrative analysis of glioblastoma multiforme
- (2017) Ying-Chun Song et al. Oncotarget
- Single-Cell RNA-Seq Analysis of Infiltrating Neoplastic Cells at the Migrating Front of Human Glioblastoma
- (2017) Spyros Darmanis et al. Cell Reports
- Glioblastoma Therapy Can Be Augmented by Targeting IDH1-Mediated NADPH Biosynthesis
- (2016) Daniel R. Wahl et al. CANCER RESEARCH
- Molecular Profiling Reveals Biologically Discrete Subsets and Pathways of Progression in Diffuse Glioma
- (2016) Michele Ceccarelli et al. CELL
- Hypoxia‐inducible factors: coupling glucose metabolism and redox regulation with induction of the breast cancer stem cell phenotype
- (2016) Gregg L Semenza EMBO JOURNAL
- Evaluation of Akt and RICTOR Expression Levels in Astrocytomas of All Grades
- (2016) Arthur William Alvarenga et al. JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY
- Proteogenomics connects somatic mutations to signalling in breast cancer
- (2016) Philipp Mertins et al. NATURE
- OmniPath: guidelines and gateway for literature-curated signaling pathway resources
- (2016) Dénes Türei et al. NATURE METHODS
- The MaxQuant computational platform for mass spectrometry-based shotgun proteomics
- (2016) Stefka Tyanova et al. Nature Protocols
- The Warburg Effect: How Does it Benefit Cancer Cells?
- (2016) Maria V. Liberti et al. TRENDS IN BIOCHEMICAL SCIENCES
- PKM2 and cancer: The function of PKM2 beyond glycolysis
- (2016) GAOCHAO DONG et al. Oncology Letters
- Metabolic Competition in the Tumor Microenvironment Is a Driver of Cancer Progression
- (2015) Chih-Hao Chang et al. CELL
- Cancer stem cells in glioblastoma
- (2015) Justin D. Lathia et al. GENES & DEVELOPMENT
- TCGAbiolinks: an R/Bioconductor package for integrative analysis of TCGA data
- (2015) Antonio Colaprico et al. NUCLEIC ACIDS RESEARCH
- Dynamic profiling of the protein life cycle in response to pathogens
- (2015) M. Jovanovic et al. SCIENCE
- The driver and passenger effects of isocitrate dehydrogenase 1 and 2 mutations in oncogenesis and survival prolongation
- (2014) Remco J. Molenaar et al. BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER
- Off-Line High-pH Reversed-Phase Fractionation for In-Depth Phosphoproteomics
- (2014) Tanveer S. Batth et al. JOURNAL OF PROTEOME RESEARCH
- Proteogenomic characterization of human colon and rectal cancer
- (2014) Bing Zhang et al. NATURE
- Compact variant-rich customized sequence database and a fast and sensitive database search for efficient proteogenomic analyses
- (2014) Heejin Park et al. PROTEOMICS
- Single-cell RNA-seq highlights intratumoral heterogeneity in primary glioblastoma
- (2014) A. P. Patel et al. SCIENCE
- The Somatic Genomic Landscape of Glioblastoma
- (2013) Cameron W. Brennan et al. CELL
- The mTORC1/mTORC2 inhibitor AZD2014 enhances the radiosensitivity of glioblastoma stem-like cells
- (2013) Jenna Kahn et al. NEURO-ONCOLOGY
- STAR: ultrafast universal RNA-seq aligner
- (2012) Alexander Dobin et al. BIOINFORMATICS
- Gross Total Resection of Glioma with the Intraoperative Fluorescence-guidance of Fluorescein Sodium
- (2012) Bo Chen et al. International Journal of Medical Sciences
- Cortactin in cell migration and cancer at a glance
- (2012) S. M. MacGrath et al. JOURNAL OF CELL SCIENCE
- Phase III Trial of Chemoradiotherapy for Anaplastic Oligodendroglioma: Long-Term Results of RTOG 9402
- (2012) Gregory Cairncross et al. JOURNAL OF CLINICAL ONCOLOGY
- Standards of care for treatment of recurrent glioblastoma—are we there yet?
- (2012) Michael Weller et al. NEURO-ONCOLOGY
- HIF-1α is critical for hypoxia-mediated maintenance of glioblastoma stem cells by activating Notch signaling pathway
- (2011) L Qiang et al. CELL DEATH AND DIFFERENTIATION
- Hexokinase 2 is a key mediator of aerobic glycolysis and promotes tumor growth in human glioblastoma multiforme
- (2011) Amparo Wolf et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Integrated Genomic Analysis Identifies Clinically Relevant Subtypes of Glioblastoma Characterized by Abnormalities in PDGFRA, IDH1, EGFR, and NF1
- (2010) Roel G.W. Verhaak et al. CANCER CELL
- Gene Expression Profile ofBRCAness That Correlates With Responsiveness to Chemotherapy and With Outcome in Patients With Epithelial Ovarian Cancer
- (2010) Panagiotis A. Konstantinopoulos et al. JOURNAL OF CLINICAL ONCOLOGY
- An ANOCEF genomic and transcriptomic microarray study of the response to radiotherapy or to alkylating first-line chemotherapy in glioblastoma patients
- (2010) François Ducray et al. Molecular Cancer
- Enrichment Map: A Network-Based Method for Gene-Set Enrichment Visualization and Interpretation
- (2010) Daniele Merico et al. PLoS One
- Systematic RNA interference reveals that oncogenic KRAS-driven cancers require TBK1
- (2009) David A. Barbie et al. NATURE
- Increased proteasome subunit protein expression and proteasome activity in colon cancer relate to an enhanced activation of nuclear factor E2-related factor 2 (Nrf2)
- (2009) A Arlt et al. ONCOGENE
- Successive and Selective Release of Phosphorylated Peptides Captured by Hydroxy Acid-Modified Metal Oxide Chromatography
- (2008) Yutaka Kyono et al. JOURNAL OF PROTEOME RESEARCH
- Comprehensive genomic characterization defines human glioblastoma genes and core pathways
- (2008) Roger McLendon et al. NATURE
Create your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create NowAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started